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Journal of Dermatology Research and Therapy is an international open access journal that delivers a focused, peer-reviewed, valuable collection of cases in all disciplines of dermatology including but not limited to Allergy Testing, Cosmetic Dermatology, Cryosurgery, Dermatopathology, Hair Transplantation, Immunodermatology, Intralesional Treatment, Laser Therapy, Mohs Surgery, Pediatric Dermatology, Photodynamic Therapy, Phototherapy, Psoriasis, Skin Cancers, Skin Lesions, Sweating Disorders, Systemic Therapies, Teledermatology, Topical Therapies, Tumescent Liposuction, Vitiligo Surgery, etc. It acts as a source of information for professionals and researchers in all the aspects of skin disorders.

Journal of Dermatology Research and Therapy is to encourage the publication of new information by providing a platform for reporting unique and rare cases of dermatology, diagnosis, management and clinic-pathologic correlations. The journal considers all the latest advances in the form outstanding research articles, letters, reviews, cases, commentaries, etc. in all aspects of dermatological Science.


Articles

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Some case reports and series presumed a link between malignancy and relapsing polychondritis. The most frequent described neoplasms have been hematological disorders especially myelodysplastic syndromes. Less commonly have also been reported solid neoplasms as colorectal cancer like our patient. We suggest that patients with RP should be monitored more carefully even .. read more


10.23937/2469-5750/1510041

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Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign condition featuring nodular or papular lesions of the dermis, subcutaneous tissue, and adjacent lymph nodes, commonly affecting the head and neck. The etiology is unknown, but case reports have thus far demonstrated an idiopathic origin. We describe here a case of ALHE .. read more


10.23937/2469-5750/1510040

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Dermatitis herpetiformis (DH) is an autoimmune bullous disease characterized by intensely pruritic, chronic, and recurrent vesicles on extensor surfaces such as the elbows, knees, and buttocks. The collection of neutrophils at the papillary tips is the typical histopathological finding, and a characteristic diagnostic feature is granular immunoglobulin A deposition in the .. read more


10.23937/2469-5750/1510039

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Skin cancer frequently occurs at or around the tip of the nose. Repair of small surface defects after resection of skin cancer therefore form an everyday problem to the plastic surgeon. The nose has a number of characteristics that make it unique when planning for reconstruction of surgical defects. The skin .. read more


10.23937/2469-5750/1510038

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Although several therapeutic agents are available for psoriatic arthritis (PsA), each has limitations. Acthar® Gel (repository corticotropin injection) is FDA-approved for treatment of acute episodes or exacerbation of PsA, but no clinical trials have investigated it for those uses. This 28-week, prospective, single-center, open-label trial included subjects with moderately to severely .. read more


10.23937/2469-5750/1510037

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Biomaterials comprise a scientific field where synthetic materials are developed for pertinent biological functions, yielding a wide diversity of new products. Although widely employed, they still require improvement for therapeutic purposes. The objective of this study was to develop poly (N-2-vinyl-pyrrolidone) (PVP), poly (vinyl alcohol) (PVAl), clay, and N-methyl glucamine hydrogels .. read more


10.23937/2469-5750/1510036

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Skin is the external organ of human body that provides protection against environmental stress. Direct and indirect damage causes skin aging. Scientists have been struggling to explore the mechanisms of skin aging and to think of ways to delay this course. The role of mast cell in regulating skin aging has .. read more


10.23937/2469-5750/1510035

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SLE patients from 34 centers in nine Latin American countries with a recent diagnosis (≤ 2 years) were studied. Socioeconomic-demographic characteristics and clinical features according to the presence of cutaneous manifestations were examined by univariable and multivariable logistic regression analyses. Their predictive value for the occurrence of other clinical manifestations was .. read more


10.23937/2469-5750/1510034

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A 53-year-old man with a history of poliomyelitis underwent left total hip arthroplasty in December 2011. His past medical history was not significant except the medical conditions described disease. The patient had developed a sore on right perianal area since March 2013 (Figure 1A), and infected sore lesion was extended to .. read more


10.23937/2469-5750/1510033

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Oily skin presents shine in excess, as well as increased pores and acne. For this reason, people with oily skin have more difficulty using cosmetics in general. This is the first report in literature to evaluate amulti-purpose dermatological emulsion containing Melaleuca alternifolia Cheel (Myrtaceae) (tea tree) oil and resveratrol for oily .. read more


10.23937/2469-5750/1510032

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Fluoroscopy induced chronic radiation dermatitis (FICRD) is a rare complication which can be difficult to diagnose and treat. Recently fluoroscopy use has increased and the diagnostic and the theuropathic fluoroscopy procedures are becoming more complex; therefore incidence of FICRD is rising. Because of presentation often occurs after months or years patients .. read more


10.23937/2469-5750/1510031

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We report a case of subintrant push of erythema nodosum caused by the Imatinib (Glivec) administration in a patient aged of 34 years old and followed for chronic myeloid leukemia. The drug provocation test was positive. In front of the recurrent, the painful character, the significant functional deficiency caused by the .. read more


10.23937/2469-5750/1510030

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Esophagitis dissecans superficialis (EDS) is a rare endoscopic finding characterized by sloughing of the esophageal mucosal lining, which has been infrequently associated with autoimmune bullous dermatoses. We report a case of a 77-year-old man who presented with diffuse mucocutaneous bullous lesions and odynophagia. Direct immunofluorescence of a skin biopsy confirmed a .. read more


10.23937/2469-5750/1510029

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Pressure ulcers are a frequent occurrence in the bedridden elderly, especially those who are over 65 years old. The healing of pressure ulcers is particularly difficult for these individuals as most of them may have different kinds of chronic illnesses and a low metabolism. Also, the healing process is complicated as .. read more


10.23937/2469-5750/1510028

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An increase of risk of malignancies such as lymphoma and non-melanoma skin cancer has been reported with the chronic use of immunomodulators in inflammatory bowel disease, particularly thiopurines. A case of a patient with ulcerative colitis after several years in immunosuppressive therapy developing multiple non-melanocytic skin neoplasms is described below. .. read more


10.23937/2469-5750/1510027

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Rosacea and Parkinson's disease (PD) are two completely different pathologies, with different outcomes, that share a common interesting feature as their proposed originating factor. Both conditions show inflammation as a pre-dominant aspect of their pathogenesis, having an important role in the excessive breakdown of connective tissue components. Metalloproteinases (MMPs) and Toll-like .. read more


10.23937/2469-5750/1510026

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The diaper rash is a common medical query in pediatric offices. Most of the time it is due to a contact dermatitis or mild infection that only requires local care for its resolution. The appearance of more severe lesions, such as ulcers, and the resistance to conventional therapy should make us .. read more


10.23937/2469-5750/1510025

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It is very likely that dermatologists will see patients who have both skin concerns and concomitant dry eye syndrome. Over 25 million Americans have some form of dry eye, and symptoms related to dry eye are one of the leading causes of visits to ophthalmologists. Dry eye syndrome can often be .. read more


10.23937/2469-5750/1510024

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Acne vulgaris is a multifactorial disease of the pilosebaceous unit as a result of androgen-induced increased sebum production, altered keratinisation, inflammation, and hair follicle bacterial colonisation by Propionibacterium acnes (P. acnes). The clinical features of acne include seborrhea, comedones, and papules and pustules. Nodules and cysts are seen in severe nodulocystic .. read more


10.23937/2469-5750/1510023

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Ten patients (8 male, 2 female) with a median age at diagnosis of 45 years were included. The median duration of the presence of skin lesions before diagnosis was 11 years. The most common sites of involvement were head and neck (80%), trunk and extremities (80-90%). Clinical features included patches and .. read more


10.23937/2469-5750/1510022

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Follicular mucinosis (FM), also known as alopecia mucinosa, is a rare inflammatory disorder that characteristically presents as follicular papules or infiltrated plaques with prominent follicular openings associated with alopecia. Histologically, the disorder is characterized by mucin deposition in the follicular epithelium and sebaceous glands. FM was classified in two distinct entities: .. read more


10.23937/2469-5750/1510021

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Melanoma is a highly aggressive tumour with poor prognosis in the metastatic stage that arises and evolves due to a myriad of genetic and epigenetic events. Among these, the interaction between epigenetic alterations (i.e., DNA methylation, histone modifications, mRNA silencing by miRNAs and nucleosome repositioning) has been recently identified as playing .. read more


10.23937/2469-5750/1510020

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Malignant melanoma is a serious health problem once the current chemotherapy exhibits resistance to traditional drugs. Several challenges must be overcome during drug design in order to increase the efficacy and safety of the new drugs. Therefore, the specific chemical release of cytotoxic agents near to the target is an attractive .. read more


10.23937/2469-5750/1510019

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Pyoderma gangrenosum (PG) is an uncommon disease characterized by necrotic ulcers that are often associated with underlying systemic disease. PG can occur at the surgical site following surgery, including orthopedic surgery, and may be commonly mistaken for postoperative infection, delaying diagnosis and resulting in wound deterioration and subsequent sequelae. Previously, 20 .. read more


10.23937/2469-5750/1510018

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Multicolour FISH was performed using a commercially available probeset (Abbott Laboratories, Abbott Park, IL), on formalin-fixed, paraffin-embedded tissue samples from 40 tumours: 20 benign melanocytic nevi, and 20 metastatic melanomas within lymph nodes, as determined by histologic assessment. Fluorescent signals for each probe were enumerated by 2 observers in 30 cells .. read more


10.23937/2469-5750/1510017

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Different approaches have been described for botulinum toxin (BTX-A) injections for face rejuvenation. Most techniques are based on the experience of the injecting physician and his/her learning curve. We describe a simplified approach to achieve accurate reproducible symmetric results with physicians of variable experience levels. .. read more


10.23937/2469-5750/1510016

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Erosive pustular dermatosis (EPD) is a cutaneous inflammatory condition, characterized by chronically non-healing lesions with sterile pustules and hyperkeratotic crusted erosions. Although rare, severe cases have been referred by dermatologists to plastic surgeons for management. The aim of this paper was to describe the presentation and management of extensive EPD as .. read more


10.23937/2469-5750/1510015

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Myostatin is a protein well described for its role in decelerating muscle anabolism. Most studies targeting the Myostatin pathway were performed in muscle wasting diseases. Recent studies unveil a potential approach to interfere with the Myostatin pathway to facilitate wound healing. We therefore reviewed the present literature for aiming the Myostatin .. read more


10.23937/2469-5750/1510014

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Over 3 million skin cancers are diagnosed in the United States each year. While the incidence of skin cancer is lower in patients of Hispanic descent, a recent report by the Center for Disease Control (CDC) found melanoma incidence rates to be significantly higher in Hispanic women under the age of .. read more


10.23937/2469-5750/1510013

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Severe obesity is commonly associated with dermatologic disorders such as intertrigo, psoriasis and hidradenitis suppurativa (HS). HS is a chronic inflammatory skin disease characterized by clusters of nodules, cysts, and abscesses that commonly affects hair bearing areas such as axilla, groin and perianal regions. Treatments of HS are complicated and vary .. read more


10.23937/2469-5750/1510012

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Morphea, Bullous morphea, Hemorrhagic bullous morphea, Hemmorrhagicmorhea, Localized scleroderma, Bullous localized scleroderma. Bullous morphea is a rare form of localized scleroderma (morphea) characterized by bullae on or around an atrophic morphea plaque. The cause of bullae formation in morphea is multifactorial, with lymphatic obstruction from the sclerodermatous process being considered as .. read more


10.23937/2469-5750/1510011

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A 31 year-old Korean woman presented with an asymptomatic, solitary, 0.5 cm-sized, skin-colored, firm, immovable mass on the antitragus of the left ear for one year (Figure 1A). She denied of previous trauma or infection. We initially suspected the mass as a dermatofibroma or nevus, because of its clinical manifestation. We .. read more


10.23937/2469-5750/1510010

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Few studies have examined sun sensitivity risk factors for cutaneous melanoma specifically in populations of Spanish descent. Previous searches were conducted in PUBMED for articles on melanoma and sun exposure through 2008. Over 300 articles were reviewed and relevant data was abstracted. These abstract forms were subsequently reviewed for studies in .. read more


10.23937/2469-5750/1510009

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Telogen effluvium (TE) is a hair disorder characterized by abrupt onset, diffuse, self-limited and excessive shedding of club hairs. The purpose of this study was to investigate serum zinc, vitamin B12 and folic acid levels as well as parameters of iron metabolism and thyroid functions in patients with chronic telogen effluvium .. read more


10.23937/2469-5750/1510008

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Jessner's lymphocytic infiltration of the skin (JLIS) is a skin condition of unknown an etiology characterized by erythematouspapules, plaques, and/or nodules located on the head, neck and upper back. Lesions usually are asymptomatic and resolve without scarring. JLIS can be similar in appearance to other benign lymphocytic infiltrates which include for .. read more


10.23937/2469-5750/1510007

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A patient with a severe form of Epidermolysis Bullosa (EB) presented after an above knee amputation and groin dissection for a 57 cm Squamous Cell Sarcinoma (SCC) of the skin and underlying soft tissue of the right leg. Five of 19 nodes were involved with SCC metastases. Standard care would involve .. read more


10.23937/2469-5750/1510006

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Mucormycosis is a potentially fatal systemic fungal infection. Risk factors include immunosuppression, organ transplantation, and diabetes mellitus. Rhinocerebral mucormycosis is the most common presentation in diabetic patients, whereas pulmonary mucormycosis is the most common presentation in patients with hematologic neoplasms. We describe an immunocompromised leukemia patient with painful ecchymotic plaques on .. read more


10.23937/2469-5750/1510005

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Vancomycin therapy is associated with several hypersensitivity reactions, the most common being the non-immunologically mediated 'red man syndrome'. Fever, rash, neutropenia, and other manifestations have also been variably associated with a vancomycin hypersensitivity reaction that is likely immunologically mediated. Here we report a 45-year old man who developed diffuse oral aphthous-like .. read more


10.23937/2469-5750/1510004

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Exogenous ochronosis is a rare condition of paradoxical skin darkening seen with use of the skin lightening agent hydroquinone. Incidence has been highest in patients with darker skin types, prolonged use, and higher concentration treatment, but has been reported with low dose (2%) as well. Here we present a rare case .. read more


10.23937/2469-5750/1510003

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This comparative split face clinical study was carried out in Laser Research Unit, College of Medicine, University of Kufa, Iraq; for the period from October 2012 to December 2013. Each patient's face was divided into two halves, each half was treated with one of the two laser devices used in this .. read more


10.23937/2469-5750/1510002

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Background: Dermoscopy, diagnostic cytology, confocal microscopy are used to improve diagnostic accuracy. Frozen section techniques have been used to control margins but not for diagnosis. Objectives: We used a new frozen section technique called immediate cutaneous diagnosis for nonmelanoma skin cancer, assessing its feasibility and accuracy in obtaining a result within .. read more


10.23937/2469-5750/1510001

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International Journal of Anesthetics and Anesthesiology (ISSN: 2377-4630)
International Journal of Blood Research and Disorders   (ISSN: 2469-5696)
International Journal of Brain Disorders and Treatment (ISSN: 2469-5866)
International Journal of Cancer and Clinical Research (ISSN: 2378-3419)
International Journal of Clinical Cardiology (ISSN: 2469-5696)
Journal of Clinical Gastroenterology and Treatment (ISSN: 2469-584X)
Clinical Medical Reviews and Case Reports (ISSN: 2378-3656)
Journal of Dermatology Research and Therapy (ISSN: 2469-5750)
International Journal of Diabetes and Clinical Research (ISSN: 2377-3634)
Journal of Family Medicine and Disease Prevention (ISSN: 2469-5793)
Journal of Genetics and Genome Research (ISSN: 2378-3648)
Journal of Geriatric Medicine and Gerontology (ISSN: 2469-5858)
International Journal of Immunology and Immunotherapy (ISSN: 2378-3672)
International Journal of Medical Nano Research (ISSN: 2378-3664)
International Journal of Neurology and Neurotherapy (ISSN: 2378-3001)
International Archives of Nursing and Health Care (ISSN: 2469-5823)
International Journal of Ophthalmology and Clinical Research (ISSN: 2378-346X)
International Journal of Oral and Dental Health (ISSN: 2469-5734)
International Journal of Pathology and Clinical Research (ISSN: 2469-5807)
International Journal of Pediatric Research (ISSN: 2469-5769)
International Journal of Respiratory and Pulmonary Medicine (ISSN: 2378-3516)
Journal of Rheumatic Diseases and Treatment (ISSN: 2469-5726)
International Journal of Sports and Exercise Medicine (ISSN: 2469-5718)
International Journal of Stem Cell Research & Therapy (ISSN: 2469-570X)
International Journal of Surgery Research and Practice (ISSN: 2378-3397)
Trauma Cases and Reviews (ISSN: 2469-5777)
International Archives of Urology and Complications (ISSN: 2469-5742)
International Journal of Virology and AIDS (ISSN: 2469-567X)
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