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ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2378-2951/1410151

Prevalence and Clinical Correlates of Spontaneous Echo Contrast in Patients on Oral Anticoagulation Undergoing Catheter Ablation for Atrial Fibrillation

Christian Grebmer, Carsten Lennerz, Amir Brkic, Patrick Blazek, Severin Weigand, Verena Semmler, Marc Kottmaier, Felix Bourier, Lena Friedrich, Elena Risse, Stephanie Brooks, Marie Kornmayer, Marta Telishevska, Tilko Reents, Christof Kolb, Gabriele Hessling and Isabel Deisenhofer

Article Type: Research Article | First Published: June 19, 2019

Spontaneous echo contrast (SEC) in the left atrial appendage (LAA) is associated with an increased risk of cerebral embolism in patients with atrial fibrillation (AF). Novel oral anticoagulants (NOACs) are increasingly prescribed as first-line therapy and have shown a comparable benefit-risk ratio compared to vitamin K antagonists (VKAs). The aim of this study was to investigate whether NOACs decrease the incidence of SEC compared to VKA. ...

 Open Access DOI:10.23937/2378-2951/1410150

Unroofed Coronary Sinus Syndrome Presenting with Early Pulmonary Hypertension

Maria E Franco-Fuenmayor, MD, Numra A Aleem, MD, Jorge D Salazar, MD, and Ashraf M Aly, MD

Article Type: Case Report | First Published: June 13, 2019

Isolated partial or complete absence of the coronary sinus roof hemodynamically behaves like an atrial septal defect and rarely causes pulmonary hypertension. We report a case of unroofed coronary sinus (URCS) presenting with post-operative cyanosis due to pulmonary hypertensive crisis following surgical repair of a ventricular septal defect at 6 months of age. He had progressively decreased stamina with gradual increase in pulmonary pressure requiring surgical closure of the URCS by 6 years of age with resolution of symptoms and normalization of the RV pressure. ...

 Open Access DOI:10.23937/2378-3656/1410271

Case Report: Necrotizing Fasciitis due to Cryptococcus Infection in Non-HIV Non-Organ Transplant

Rbab Taha, Mohamed Alama, Hessa Aljhdali, Ayaz khan and Reham Kaki

Article Type: Case Report | First Published: June 12, 2019

We are presenting 67-year-old female, known to have diabetes for 10 years, not compliance to medication. Presented with 3 weeks history of isolated right lower limb and left thigh pain. Then she started to develop redness and swelling in same areas. She had also History of dry cough for one week. Admitted as a case of necrotizing fasciitis based on clinical laboratory and radiological features. She was treated empirically with vancomycin and meropenem and went for debridement twice. Histopathology and culture showed Cryptococcus neoformans. Investigations were done to rule out other immune sys...

 Open Access DOI:10.23937/2572-4053.1510022

Novel Anti-Snoring Mouthpiece to Reduce Snoring in At-Home Study

Jonathan Greenburg, DDS, Jesse Cozean, MBA and Colette Cozean, PhD

Article Type: Clinical Trial | First Published: June 10, 2019

Habitual snoring affects millions of individuals and their partners, but often goes unresolved due to the high cost of care and other barriers to treatment. The purpose of this study was to evaluate the effectiveness of a novel intraoral device that restrains the tongue in an overthe- counter setting in a population of habitual snorers. Individuals who self-reported snoring enrolled in the study and were sent an investigational device. After signing the informed consent, they completed an initial questionnaire about their symptoms and another following 10 days of using the device....

 Open Access DOI:10.23937/2378-3516/1410110

Association of Pulmonary Function with Waist Circumference (WC) and Body Mass Index (BMI) among the Students of Management & Science University, Malaysia

Aniruddha Bhattacharjee, Aye Aye Myat, Shakunthala VT and Rajeev Sharma

Article Type: Research Article | First Published: June 10, 2019

Obesity is rapidly escalating in Malaysia in all age groups. Prevalence of obesity and overweight is increasing in adults and in children in both developed and developing countries. Obesity is a risk factor for many conditions including respiratory disorders regardless of BMI. However, studies investigating pulmonary functions in obese adolescents in Malaysia are few. Hence, the present study was aimed to investigate pulmonary function variables in the adolescent obese students of management and science university (MSU) in Malaysia. To evaluate the effect of obesity on pulmonary function among...

 Open Access DOI:10.23937/2378-3656/1410270

Of Philosophy, Ethics and Moral about Euthanasia: The Discomfort between Modernity and Postmodernity

Euler Renato Westphal, Woryk Schoeder Nowak and Caciano Vinicius Krenchinski

Article Type: Research Article | First Published: June 10, 2019

To define euthanasia, as well as orthanasia, misthanasia and dysthanasia, to start from this, to discuss the different philosophical, ethical and moral visions that surround the subject. Exploratory qualitative study which defined from the existing literature the pertinent concepts and from them brought discussions about euthanasia....

 Open Access DOI:10.23937/2378-3672/1410036

S-Nitrosoglutathione Modulates Expansion of Activated CD4CD25 Cells by Apoptosis under Inflammatory Condition

Subhajit Dasgupta

Article Type: Research Article | First Published: June 08, 2019

The regulation checkpoints of CD4CD25 expansion in presence and absence of transcription factor FOXP3 are critical to maintain balance between inflammatory TH17 and anti-inflammatory FOXP3CD4CD25 Treg cells. We investigated impact of potent inflammatory mediator nitric oxide NO(.) on commitment of normal spleen T cells following activation. The single cell suspension of healthy C57BL/6 mice splenic CD4 cells was stimulated by plate-bound antiCD3/antiCD28 antibodies in presence of cytokine cocktail IL2, IL6, TGFβ and anti-IL4, anti-IFN γ antibodies with and without GSNO for 72h. The results s...

 Open Access DOI:10.23937/2643-4474/1710016

Psychogenic Hemiplegia after Cervical Spine Discectomies and Fusion

Siavash S Haghighi

Article Type: Case Report | First Published: June 08, 2019

A case report of psychogenic hemiplegia following a two level anterior cervical discectomies and fusion was contradicted by a thorough electrophysiological findings. To report an unusual case of post-operative hemiplegia in spite of normal electrophysiological and noncompromising radiographic findings. Conversion disorder with sensory or motor system symptoms is a subtype which includes symptoms such as impaired motor balance, paraplegia, muscle weakness, and urinary retention....

 Open Access DOI:10.23937/2474-3690/1510040

Lactate Dehydrogenase in Hypertensive Disorders in Pregnancy: Severity or Diagnosis Marker?

Fernando Vazquez-Alaniz, Jose Manuel Salas-Pacheco, Ada Agustina Sandoval-Carrillo, Osmel La-llave-Leon, Edna Madai-Mendez Hernandez, Marcelo Barraza-Salas, Eda Guadalupe Ramirez- Valles, Norma Urtiz-Estrada, Mario Lumbreras Marquez, Jose Miguel Montes-Herrera and Cesar Yhamel Sanchez-Bernal

Article Type: Research Article | First Published: June 06, 2019

Lactate dehydrogenase has had an exciting journey as a utility marker in different illnesses, but currently, its clinical utility has been relegated to confirm hemolysis, as a tumor marker, and as a diagnostic biomarker of preeclampsia. The findings of lactate dehydrogenase concentrations taking reference values to healthy persons are not consistent when these are related to hypertensive disorders in pregnancy, mainly to begin symptoms or little severity presentation. The goal in this work was to evaluate the maternal serum concentration of lactate dehydrogenase and its utility as a severity o...

 Open Access DOI:10.23937/2643-4091/1710009

The Effect on Disc Height and Sagittal Alignment in 56 Consecutive Patients Undergoing Lateral Access Surgery

Donald A Deinlein, Sakthivel Rajaram, Jorge L Perez and Mason B Frazier

Article Type: Research Article | First Published: June 06, 2019

The lateral approach to the spine, for spinal fusion, has gained interest from spine surgeons in recent years. The approach is less invasive, with less blood loss, decreased morbidity, and decreases length of stay in the hospital. The procedure has been shown to allow indirect decompression of the spinal canal and the intervertebral foramen. Segmental interbody arthrodesis may result in improved coronal and sagittal balance....

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