Journal of Geriatric Medicine and Gerontology is an international, open access, peer reviewed journal that publishes wide variety of information in areas of clinical, preventative, curative and social aspects of illness in old age. The main objective of the journal is to set a forum for publication, education, and exchange of opinions, and to promote research and publications globally. The Journal provides a platform for all clinicians, surgeons and health professionals to contribute their findings and help raise awareness among community in various aspects of gerontology. We aim to publish highest quality clinical content via open access platform providing the readers free, immediate and unlimited access.
Journal of Geriatric Medicine and Gerontology is an open journal focusing on Aging Demographics, Biogerontology, Aging Process, Geroscience, Aging Population, Biological Theories of Aging, Genetics Factors, Social Geronotology, Psychological Gerontology, Environmental Gerontology, Nutrition and Aging, Aging and Memory, Aging Portfolio, Biological Clock and Epigenetic Clock, Elderly Care, Life Extension, Geriatric Medicine, Geriatric Giants, Cardiogeriatrics, Geriatric Dentistry, Geriatric Dermatology, Geriatric Diagnostic Imaging, Geriatric Emergency Medicine, Geriatric Nephrology, Geriatric Neurology, Geriatric Oncology, Geriatric Pharmacotherapy, Psychogeriatrics, Preventive Geriatrics, Geriatric Rehabilitation, Geriatric Rheumatology, Geriatric General Surgery, Geriatric Trauma, Geriatric Nutrition, Geriatric Podiatry, etc. The journal accepts various manuscript formats such as Original Article, Reviews, Mini Reviews, Short Communications, Case Reports, Perspectives/Opinions, Letters, Short Note and Commentaries. All articles published in the journal are subject to a rigorous peer review process. It encourages authors to publish their experimental and theoretical results in detail to disseminate the updated research findings.
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2469-5858/1510105
Robert J Fischer, MD, Kimberly K Morris, MD, Luke A McCorkel, BA, MA, Steven M Case, RN, BSN, CCM, ACM-RN, Hieu H Pham, RN, BSN and Brian G Henneman, PE
Article Type: Original Article | First Published: December 05, 2020
Determine LTCF risk factors for a COVID-19 outbreak and recommend strategies for closing gaps in facility preparedness through a multidisciplinary team assessment carried out on site. Data was obtained during visits to 14LTCFs, completion of a standard assessment tool through interviews with site staff and leadership and tours of the facility campus. In all five dimensions of preparedness (staffing, professional medical support, infection control, engineering controls and testing), the degree of...
Open Access DOI:10.23937/2469-5858/1510104
Daniel J Greenberg, DO and Christine Carosella, MD
Article Type: Case Report | First Published: December 05, 2020
Most patients with coronavirus disease 2019 (COVID-19) experience fever, cough, and malaise. Neurologic manifestations are receiving more recognition. One systematic review found the most frequent findings included headache (20.1%) and smell and taste dysfunction (59.2% and 50.8%, respectively). Impaired consciousness, defined as agitation or confusion, occurred 5.1%, and was more common in severe or critical patients (11.9%). Further, cases of asymptomatic infection may be as high as 40% to 45%...
Open Access DOI:10.23937/2469-5858/1510103
Yuan Zong, Masashi Tanaka, Masaaki Muramatsu and Tomio Arai
Article Type: Case Study | First Published: November 25, 2020
Werner Syndrome (WS) is a rare autosomal recessive disorder characterized by symptoms of premature aging, including elevated risk of malignancies. The causative WRN gene encodes a DNA helicase, which maintains the integrity of the human genome. While WS patients have functional null mutations in both alleles of the WRN gene, phenotypes of heterozygote carriers have not been described. Cellular assays showed that heterozygote carriers also have genetic instability to a lesser extent. To this end ...
Open Access DOI:10.23937/2469-5858/1510102
Noelia Carolina Del Castillo Salazar, Martin Luis Figueroa Velásquez, Jesús Ojino Sosa-García, and José Ángel González Sánchez
Article Type: Original Article | First Published: November 21, 2020
We analyzed the open data of COVID-19 from the Mexican government from March 19th to June 19th, 2020. A total of 141,009 cases were included, where 7,394 patients were aged over 65 years with a positive RT-PCR test for SARS-CoV-2. We investigated symptoms, comorbidities, pneumonia diagnosis, the need of hospitalization, orotracheal intubation, and intensive care unit [ICU] admission. The data were analyzed with SPSS version 25.0 for Windows. In a population aged over 65 years, 57% (n = 3,899) we...
Open Access DOI:10.23937/2469-5858/1510101
Joseph O Nnodim, MD, PhD, FACP, AGSF, Chinomso V Nwagwu, MD and Ijeoma Nnodim Opara, MD, FAAP
Article Type: Structured Review | First Published: October 23, 2020
Human beings propel themselves through their environment primarily by walking. This activity is a sensitive indicator of overall health and self-efficacy. Impairments in gait lead to loss of functional independence and are associated with increased fall risk. This structured review examines the basic biology of gait in term of its kinematic properties and control. It describes the common gait disorders in advanced age and proposes a scheme for their recognition and evaluation in the regular ambu...
Open Access DOI:10.23937/2469-5858/1510100
Antony Soares Dionísio, João Filipe Gomes and Manuel Teixeira Marques Veríssimo
Article Type: Original Research | First Published: October 22, 2020
The main purpose of this study is to assess the prevalence of elder abuse in Portugal, more specifically in a central hospital in Coimbra and its impact on victims’ health. The analysis of the results concludes that 36% of the participants report experiencing at least one indicator of abuse. There is a relation between the number of abuse indicators and the female gender, low educational level, depressive symptoms, increased functional dependence and health status. Mistreatment in the elderly ...
Open Access DOI:10.23937/2469-5858/1510099
Robert J Fischer, MD
Article Type: Case Report | First Published: September 30, 2020
Recurrent viral shedding (RVS) in COVID-19, between four and 31 days following a test of cure, has been noted in the medical literature. Here we describe a case of recurrent and protracted viral shedding in a nursing home patient admitted to the hospital. Following symptomatic COVID-19 and viral shedding for 36 days with subsequent test of cure, a further positive RT-PCR was obtained 45 days later when the formerly symptomatic patient was readmitted for urgent urinary tract surgery. The total ti...
Open Access DOI:10.23937/2469-5858/1510098
Nicholas J Thompson, MD, Margaret E Richter, BA, Margaret T Dillon, AuD, and Harold C Pillsbury, MD
Article Type: Review Article | First Published: September 30, 2020
Older adults who qualify for cochlear implantation demonstrate significant improvements in speech recognition and quality of life with cochlear implant use. Cochlear implantation is a safe and effective procedure for patients with hearing loss, with some additional medical considerations specific to older adult patients. The indications for cochlear implantation have expanded from cases of bilateral severe- to-profound hearing loss to cases of normal-to-moderate low-frequency hearing sensitivity...
Open Access DOI:10.23937/2469-5858/1510097
Andrea Ferrazza, Claudia Bellini, Ingrid Bordanzi, Marialuigia Praitano and Rita Vedovello
Article Type: Original Article | First Published: September 18, 2020
Long term care facilities are the homes of elderly people worldwide; due to vulnerability and rapid spread of infection (droplets or fomites) the risk of severe outcomes from outbreaks of COVID-19 is of concern. We analyzed data of cases from the beginning of the epidemic, confronting clinically suspected patients (absence of nasopharyngeal testing -T0) with symptomatic COVID-19 patients (availability of rRT-PCR testing - T1); all data were censored after complete nasopharyngeal swab SARS-CoV-2 ...
Open Access DOI:10.23937/2469-5858/1510096
Pooja Nair, Aileen Nguyen, Nishita Nigam and Abraham Kanal
Article Type: Perspective Piece | First Published: August 20, 2020
Delirium is a frequently encountered condition in hospital medicine and can be associated with extended hospitalizations as well as higher rates of morbidity and mortality, with significant impact on the elderly population. The COVID-19 pandemic is expected to increase the burden of delirium amongst hospitalized patients. Thus far, evidence-based interventions that have been shown to be effective in preventing and reducing the morbidity associated with this condition include early screening and ...
Open Access DOI:10.23937/2469-5858/1510095
Fabiana Tezza, MD, PhD, Angela Susana, MD, Jacopo Monticelli, MD, Lucia AC Leone, MD and Sofia Barbar, MD
Article Type: Case Report | First Published: July 22, 2020
About 40% of SARS-CoV-2 positive patients are asymptomatic but infectious. More common symptoms are fever, dry cough and dyspnea but some patients might experience also myalgia, diarrhea, anosmia and ageusia. Severe cases present a severe pneumonia that could exitate in an acute respiratory distress syndrome (ARDS) characterized by acute hypoxemic respiratory failure and bilateral lung infiltrates...
Open Access DOI:10.23937/2469-5858/1510094
Antoine Briantais, Margaux Froidefond, Julie Seguier, Laure Swiader and Jean Marc Durand
Article Type: Case Report | First Published: July 22, 2020
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common worldwide distributed hereditary red cells enzymatic defect, with a prevalence of 400 million affected subjects. It is a benign haematologic disorder, acute haemolytic crisis triggered by exposition to oxidative agents such as fava beans, drugs or infections might be its most common life-threatening clinical presentation. Although G6PD deficiency is X-linked recessive disorder, females are expected to have normal G6PD level. ...
Open Access DOI:10.23937/2469-5858/1510093
Pallavi Shah, Alhareth Alsayed, Waseem Ahmed, Shreya Desai, Mohamed Shanshal and Janos Molnar
Article Type: Original Research | First Published: July 11, 2020
Current guidelines for colorectal cancer recommend starting screening at age 50 until 75 years. The primary objective was to compare survival in patients 50-74 years-old versus older patients. Retrospective chart reviews were performed on patients who underwent screening, diagnostic or surveillance colonoscopy at JAL FHCC. 213 patients were included with 51% of the patients aged 50-74 years and 49% aged 75 years or older. Survival time was higher in the younger group with mean survival time (MST...
Open Access DOI:10.23937/2469-5858/1510092
Kalpana P Padala, MD, MS, Ashlyn M Jendro, MS, Kerrie B Wilson, MS, Prasad R Padala, MD, MS
Article Type: Review Article | First Published: June 29, 2020
Technology use has been recommended as a way to assess and mitigate loneliness. This advice is more applicable now during the COVID pandemic. It is known that social networks mitigate the detrimental effects of loneliness by enhancing physical and mental health. Unfortunately, even in normal circumstances, it is difficult for older adults to maintain social networks. Although face-to-face interaction is the ideal way of social networking, literature supports that technology has a role in combati...
Open Access DOI:10.23937/2469-5858/1510090
Wells TS, Karl JL, Bhattarai GR, Nickels LD and Yeh CS
Article Type: Original Research | First Published: June 11, 2020
The primary objective was to explore falls risk associated with hearing impairment (HI), vision impairment (VI), and hearing aid use among older adults. Participants (4,414) were categorized into six groups: no HI or VI, aided and unaided dual sensory impairment (DSI), aided and unaided HI only, and VI only. Falls risk included falling, being unsteady, and worried about falling. Individuals with DSI had the highest falls risk, generally followed by VI only and then HI only. The use of hearing ai...
Open Access DOI:10.23937/2469-5858/1510091
Davide Moro, Giacomo Gastaldi, Dina Zekry and Christine Serratrice
Article Type: Original Research | First Published: June 11, 2020
We report the case of a 75-year-old woman, admitted to the emergency geriatrics unit because of asthenia, non-bloody watery diarrhoea, vomitus and flu-like symptoms, started two days earlier. She had also rhinorrhoea without dyspnea, abdominal or chest pain. As far as she knew, she had no contact with Covid-19 infected individuals. She had no relevant medical history and no known allergies. She was non-smoker and had no history of alcohol consumption. She is married, the couple has a son and she...
Open Access DOI:10.23937/2469-5858/1510089
Michelle C N Dorneles, Denis F Souza, Ercilhana G B Freitas and Sebastião R Ferreira-Filho
Article Type: Research Article | First Published: April 24, 2020
Aging and hypertension are common factors in increased central arterial stiffness and the prevalence of atrial fibrillation (AF). Individualized weighing of the risk-benefit of anticoagulation is recommended in patients with AF who have low established risk scores or, conversely, are at increased risk for bleeding. Parameters of arterial stiffness and wave reflection could improve risk stratification....
Open Access DOI:10.23937/2469-5858/1510088
Atsushi Hamuro, MD, PhD, Minoru Honda, Hideki Kawaguchi and Hoai Noguchi
Article Type: Short Note | First Published: April 23, 2020
Chronic constipation is a common gastrointestinal disorder and it impairs patients’ quality of life (QOL). Because of their reduced cognitive function, dementia patients often find it difficult to verbalize the abdominal discomfort caused by constipation and bloating, and it can lead to ileus and loss of appetite. Although stimulant and osmotic laxatives, and enemas are commonly used to treat constipation, it has been reported that they can cause dependency, cathartic colon, and hemorrhoids...
Open Access DOI:10.23937/2469-5858/1510087
Sarah Pakzad, Paul Bourque and Nader Fallah
Article Type: Research Article | First Published: April 03, 2020
According to Statistics Canada in 2014, 23.4% of Canadians aged between 45 and 64-years-old, and 47, 4% of adults aged 65 years and older were diagnosed with hypertension. Given the significant association between hypertension and cognitive decline, and consequently on frailty status, the contribution of Neurocognitive Frailty Index in the assessment of patient’s prognosis is of utmost importance. Hence, the prognostic utility of the Neurocognitive Frailty Index (NFI), a comprehensive measure ...
Open Access DOI:10.23937/2469-5858/1510085
Nienke E Dijkstra, MSc, Carolien GM Sino, PhD, Marieke J Schuurmans, PhD, Marcel L Bouvy, PhD, Aline Bouwes, PhD and Eibert R Heerdink, PhD
Article Type: Research Article | First Published: February 03, 2020
Home care professionals regularly observe drug-related problems during home care provision. Problems related to the process of the medication therapy could involve discrepancies in medication prescriptions between the hospital discharge letter and the medication administration record lists (MARL) or insufficient drug delivery. The objective of this study is to determine the potential clinical consequences of medication process problems observed by home care professionals, since those consequence...
Open Access DOI:10.23937/2469-5858/1510084
Brunilda Elezi, Erjona Abazaj, Marsida Kasa and Skender Topi
Article Type: Research Article | First Published: January 27, 2020
Frailty is considered often as a physical impairment in the elderly and its characteristics are weakness, weight loss, exhaustion, a decrease of the physical activity accumulating also comorbidity. It is considered the geriatric syndrome related to the aging process, declining of biological reserve that results in an increase of vulnerability for negative results including disability, hospitalization, and death. Frailty was defined as “a state of increased vulnerability on the stress factors d...
Open Access DOI:10.23937/2469-5858/1510083
Article Type: Research Article | First Published: January 22, 2020
Low BMI is a poor prognostic factor. Previous studies have reported that daily body activity (ADL) ability is difficult to improve if the body mass index (BMI) at admission is low, but the relationship between BMI at discharge and ADL ability has not been clarified. Therefore, we aimed to clarify that ADL ability is low when BMI at discharge is low. A cross-sectional study of patients who were admitted to an integrated community care ward and underwent rehabilitation. Patient information was in...
Open Access DOI:10.23937/2469-5858/1510082
Andrew Giaquinto, Pharm D, Ashmi A Philips, Pharm D, AAHIVP, Michael Casias, Pharm D, BCIDP, Navin Philips, Pharm D, BS, DPLA, and Geralyn M Prosswimmer, MD, FAAP
Article Type: Research Article | First Published: November 04, 2019
The purpose of this project was to conduct pharmacotherapeutic management of patients in the outpatient setting in a standardized manner. A CMR program was implemented at select ambulatory care sites within our healthcare system. This review identified and addressed medication-related concerns in order to optimize disease state management and attain positive patient outcomes. This prospective review included patients 80 years or older with polypharmacy concerns, categorized as having greater tha...
Open Access DOI:10.23937/2469-5858/1510081
Semra Gundogdu, Fatma Arikan and Gokhan Keser
Article Type: Research Article | First Published: November 01, 2019
The older adults, in particular, care more about quality of life than longevity. Therefore, initiatives for the elderly should focus on increasing the quality of their life. Many factors affect the older adults' quality of life, but their dependence level is the most important. This study examined the effect of dependence level on quality of life for older adults living in nursing homes. The sample of this descriptive, cross-sectional study included 109 older adults who lived in nursing homes. D...
Open Access DOI:10.23937/2469-5858/1510080
Satoru Sakuragi, Nobuhisa Kodera, Toshihiro Iida, Takashi Yamada, Mitsutaka Nakashima, Atsushi Mori, Yuji Koide, Tadashi Wada, Kenji Kawamoto, Machiko Tanakaya and Yusuke Katayama
Article Type: Research Article | First Published: November 01, 2019
Recent reports have indicated a marked impairment of physical function in patients with acute cardiac disease. In addition, further deterioration in physical activity has been found during hospitalization especially in elderly patients, which may be associated with poor outcome after discharge. In this study, we repeatedly measured gait speed (GS) during hospitalization and evaluated the association of change in GS with mortality after discharge. From January 2015 to October 2017, we enrolled 44...
Open Access DOI:10.23937/2469-5858/1510079
Sumeyra Mihrap ILTER, Ozlem OVAYOLU and Nimet OVAYOLU
Article Type: Research Article | First Published: October 26, 2019
The aim of this study is to investigate the relationship between foot care behaviors and metabolic control parameters of the elderly individuals diagnosed with diabetes. The study was carried out as a descriptive study in a training and research hospital between February and July 2017. The study was conducted with patients diagnosed with diabetes. Data of the research; the questionary form was obtained with some laboratory results from the foot care scale (FCS) and patient records. In this study...
Open Access DOI:10.23937/2469-5858/1510078
Karen Farrell and Akke Vellinga
Article Type: Narrative Review | First Published: October 18, 2019
Urinary incontinence (UI) is highly prevalent in elderly people residing in nursing homes. Care staff often lack the knowledge and management skills to effectively care for and treat residents with UI. The implementation of standardised treatment interventions at the individual or nursing home level can help to successfully manage and reduce UI in elderly residents. MEDLINE and PubMed were searched from 2005-2019 using selective search strategies, detailing interventions and randomised controlle...
Open Access DOI:10.23937/2469-5858/1510077
Recep Dincer, Halil Burc, Y Barbaros Baykal, Tolga Atay and Vecihi Kirdemir
Article Type: Research Article | First Published: October 03, 2019
Recent technological advancements and accumulating surgical experience have led to a higher interest in orthopedic minimally invasive surgery. This study aims to present the feasibility of posterior mini-incision for partial hip prosthesis compared with total hip prosthesis. In all patients, a mini-incision of 8.5-cm mean length was used. The mean surgical duration was 67.4 min, and the mean blood loss was 526 mL. We observed no neurovascular damage in any patient resulting from the limited expo...
Open Access DOI:10.23937/2469-5858/1510076
Selina Cheong Tingting, Goh Wen Yang, Ong Eng Hui, Siti Nurhana Abdul Karim, See Lin Li and Edward Chong Kah Chun
Article Type: Research Article | First Published: September 18, 2019
The complex interplay between altered pharmacokinetics and pharmacodynamics, greater multimorbidity and polypharmacy, are associated with increased risk of adverse drug reactions (ADR) in older adults. There remains a paucity of data on the association between frailty and ADRs. We aimed to determine the association between frailty and the prevalence, presentation and severity of ADRs among hospitalized older adults. This was a retrospective, cross-sectional study in an acute care hospital in Sin...
Open Access DOI:10.23937/2469-5858/1510075
Ruth E Taylor-Piliae, PhD, RN, FAHA, Chiu-Hsieh (Paul) Hsu, PhD, Hanne Dolan, MSN, RN, PhD Student, Nima Toosizadeh, PhD and Jane Mohler, NP-C, MPH, PhD4
Article Type: Research Article | First Published: September 16, 2019
A Matter of Balance (MOB) is a national community-based fall prevention program focusing on cognitive restructuring to manage concerns about falling, though does not include a balance-training component. A dual-task balance challenge (DTBC) comprising weight transfer using fixed and random ordering of ankle-reaching balance tasks was added to MOB, to determine of this would lead to reduced fall risk. The study aims were to assess acceptance, satisfaction, safety and adherence to the intervention...
Open Access DOI:10.23937/2469-5858/1510074
Jung-Ting Lin, Chin-Kai Huang, Lan-Yin Huang, Pei-Ying Wu and Yu-Fang Huang
Article Type: Research Article | First Published: September 12, 2019
Acute or chronic lower urinary tract symptoms (LUTS) may be secondary to labial fusion in menopause. Early detection and treatment may help prevent progression of the condition. A 61-year-old, nulligravida, postmenopausal woman without sexual experience presented with partial labial fusion accompanying urinary tract infection and urinary retention. There was no follow up and five years later, when a transurethral catheterization failed during surgery for head and neck cancer, complete labial fus...
Open Access DOI:10.23937/2469-5858/1510073
Kalen Hendra, MD, Catherine Sims, MD and Soheir Boshra, MD
Article Type: Research Article | First Published: September 11, 2019
Numerous studies have shown that music therapy (MT) and music listening (ML) can improve patient symptoms such as anxiety, pain, and relaxation. To investigate the effect of multiple ML sessions and the association between patient expectations and outcomes, patients were recruited from two nursing and rehabilitation centers in Roanoke, Virginia. Patients received three 30-minute ML sessions (experimental) or no intervention (control). Patient data included the Edmonton Symptom Assessment System ...
Open Access DOI:10.23937/2469-5858/1510072
Schurov Vladimir Alekseevich, MD and Melnikova Lyudmila Vasilievna
Article Type: Research Article | First Published: August 30, 2019
Treatment of patients with fractures of the bones of the leg in an outpatient setting occurs under conditions of a forced increase in the axial load on the injured lower limb. The aim of the study was to determine the conditions for the formation of periosteal callus of the shoulder and lower leg and to assess the effect on its formation of the time frame for fixation of bone fragments in people of different ages under the conditions of treatment in the outpatient setting. In patients with a leg...
Open Access DOI:10.23937/2469-5858/1510071
Arif YUKSEL, Can Ahmet KULAN, Rifat Reha BILGIN, Yaprak Ozum UNSAL, Nuri YURTMAN , Fehmi AKCICEK and Hatice ULUER
Article Type: Research Article | First Published: August 02, 2019
As one gets older, some changes occur in swallowing mechanisms. The non-symptomatic swallowing disorders associated with aging for no reason are called presbyphagia. Whether or not presbyphagia has any cause other than the mechanisms of aging is not clear. In our study, we investigated the association of presbyphagia with hypertension, diabetes, and obesity. Early detection of presbyphagia is important, and it is also important to reveal its association with common diseases encountered in societ...
Open Access DOI:10.23937/2469-5858/1510070
Prof. Jochanan E Naschitz, MD
Article Type: Research Article | First Published: May 02, 2019
Study Part I is a cross-sectional point of care assessment of data which might distinguish dehydrated from euhydrated subjects. Twelve potential markers of dehydration were evaluated: inadequate fluid intake, vomiting, diarrhea, bleeding, diuretic treatment, serum sodium, serum urea and creatinine, urea/creatinine ratio, estimated glomerular filtration rate, hemoglobin and serum albumin. Study Part II is a longitudinal survey of patients at risk of dehydration under changing clinical conditions....
Open Access DOI:10.23937/2469-5858/1510069
Article Type: Commentary | First Published: April 29, 2019
In the beginning of the century L. Boltzmann was the first to represent the increasing entropy process as a time flowing characteristic. Besides, he pointed at a possible time reversion process in micro systems. A symbol of aging of any system - alive or inanimate is the entropy increasing. Is this process reversible? For short periods - yes and biological systems represent examples of it. Unfortunately, any reversing of the entropy sign in these systems is possible only for short periods of tim...
Open Access DOI:10.23937/2469-5858/1510068
Satoru Sakuragi, Nobuhisa Kodera, Toshihiro Iida, Takashi Yamada, Mitsutaka Nakashima, Atsushi Mori, Yuji Koide, Tadashi Wada, Kenji Kawamoto, Machiko Tanakaya and Yusuke Katayama
Article Type: Original Article | First Published: April 24, 2019
Elderly patients have impaired physical function, which is further reduced by the incidence of hospitalization for heart failure. In these patients, nutritional status also deteriorates during hospitalization, which may cause impairment in their physical function. In this study, we repeatedly measured physical function using gait speed (GS) during hospitalization, and evaluated the factors including nutritional status that are associated with GS at discharge in elderly patients with acute heart ...
Open Access DOI:10.23937/2469-5858/1510067
Atilla Tutak, oznur Uludag, M Bahattin Pektas, Recai Kaya, Mevlut Dogukan, Ayse sahin Tutak
Article Type: Case Report | First Published: April 04, 2019
Geriatric age group; Increased sensitivity to anesthetic drugs, respiratory, general anesthesia due to cardiac complicatioans and cognitive dysfunction in the postoperative period is restricted. Combined spinal epidural anesthesia compared to general anesthesia and cardiac and respiratory stabilization, the extension of the duration of anesthesia, rapid mobilization, postoperative pain control, the advantages of early discharge and a reduction in costs. High doses of spinal or epidural anesthesi...
Open Access DOI:10.23937/2469-5858/1510066
David Sanchez-Teruel and Maria Auxiliadora Robles-Bello
Article Type: Research Article | First Published: April 03, 2019
Suicide attempts double death by suicide rates. To date it remains the only behavior that predicts more harmful future reattempts or deaths from suicide. However, few studies have analyzed the sociodemographic and clinical profiles of older adults who have suffered self-inflicted injuries or attempted suicide. To assess which sociodemographic and clinical variables are more predictive of a high-lethality or definitive future suicide reattempt in older adults who have suffered self-inflicted inju...
Open Access DOI:10.23937/2469-5858/1510065
Stephanie L Inat, Tiffany K Gill and Jodie C Avery
Article Type: Research Article | First Published: March 20, 2019
Faecal Incontinence (FI) is a common debilitating condition that, significantly decreases health-related quality of life (HRQoL). However, there is uncertainty about its prevalence and the factors that modulate the relationship between FI and HRQoL, which reduces the efficiency and effectiveness of clinical and public-health interventions. Data was taken from the 2004 representative cross-sectional population South Australian Health Omnibus, n = 3015 men and women aged 15 and over. The main outc...
Open Access DOI:10.23937/2469-5858/1510064
Ines Rego de Figueiredo, Rita Vieira Alves, Sara Guerreiro Castro, Filipa Lourenco, Ana Margarida Antunes, Manuela Martins, Heidi Gruner and Antonio Panarra
Article Type: Case Report | First Published: March 18, 2019
The diagnosis of a neck mass can present a challenge. In the adult the most common diagnosis is malignancy, and both primary and metastatic tumors should be considered. Other frequent options are infectious processes. We present the case of an 88-year-old female patient with a submandibular mass with inflammatory signs, unresponsive to antibiotic therapy, with fine needle aspiration biopsy showing an inflammatory lesion. The mass developed over a month with associated anorexia resulting in admis...
Open Access DOI:10.23937/2469-5858/1510063
Niele Silva de Moraes, Thais Priscila Biassi, GrazielleMecabo, Elvira Maria Guerra Shinohara, Maysa Seabra Cendoroglo, Thiago Xavier Carneiro and Maria Stella Figueiredo
Article Type: Research Article | First Published: March 14, 2019
The decline in haemoglobin (Hb) levels with advanced age is a widely known event. Nevertheless, it remains unclear whether this is a normal consequence of aging or a feature of age-related comorbidities. The World Health Organisation (WHO) definition of anaemia, although commonly used, was based on small epidemiological data and did not include individuals over 64-years-old. The aim of the present study is to evaluate haemoglobin levels and establish a reference range for a Brazilian population ...
Open Access DOI:10.23937/2469-5858/1510062
Jefferson Teixeira Oliveira, Mateus Silva Santos, Wesley Vieira Naves, Hygor Lima Costa, Andressa Santana Santos, Vivianny Aparecida Queiroz Freitas, Maria do Rosario Rodrigues Silva, Milton Camplesi Junior, Antonio Marcio Teodoro Cordeiro Silva and Fabio Silvestre Ataides
Article Type: Research Article | First Published: February 15, 2019
Onychomycosis is fungal nail infection, which can be associated with some factors, such as decreased nail growth and immunodeficiency, makes the elderly predisposed to onychomycosis. The objective of this study was to investigate the frequency of onychomycosis in elderly institutionalized, and to verify the effects that the infection had in their daily routine. This study was carried in gerontological complexes of Goiânia, Goias, Brazil, with 58 elderly who exhibited clinical suspicion of onych...
Open Access DOI:10.23937/2469-5858/1510061
Neide AP Nascimento, Patricia FP Moreira, Vanessa A Carvalho, Levy Aragao, Rosangela Villa Marin-Mio, Marise Lazaretti-Castro and Maysa S Cendoroglo
Article Type: RESEARCH ARTICLE | First Published: January 23, 2019
Global awareness on vitamin D deficiency and its consequences has been increasing. Furthermore, there is substantial agreement among all guidelines that serum 25(OH)D concentrations < 25-30 nmol/L should be avoided in all age groups. In addition, hypovitaminosis D is a world health problem, and Brazil has an elevated prevalence of hypovitaminosis D among its population. In general, a 25(OH)D level of less than 20 ng/mL has been associated with neuromuscular performance issues in elderly people i...
Open Access DOI:10.23937/2469-5858/1510060
Yun-Tai Chen, Yu-Liang Chen, Fu-Yang Ko and Lun-Chien Lo
Article Type: Short Review | First Published: January 23, 2019
Traditional Chinese Medicine (TCM) emphasizes the combination of: The physical, psychological, spiritual, social, and environmental aspects. These aspects encourage human beings to live in harmony with the rhythm of nature. We believe these principles match with up the ideas of holistic care, and the characteristics of TCM therapies are much gentler and safer for the elderly. Nowadays, significant evidence supports the effectiveness and safety of TCM for seniors' health care. In this short revie...
Open Access DOI:10.23937/2469-5858/1510059
NAHTIGAL KLEVISAR Mirijam, LUSA Lara, TERZIC Sara, MUELLER-PREMRU Manica, PIRS Mateja and STUPICA Dasa
Article Type: RESEARCH ARTICLE | First Published: January 21, 2019
The preference for empiric antibiotic therapy with carbapenems over non-carbapenems in all extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) colonized patients with sepsis warrants further investigation from an ecologic perspective; even more so in the elderly (≥ 65 years) because the proportion of ESBL-E in adults increases with patients' age. In this retrospective observational study, enrolling 547 ESBL-E colonized elderly patients with community-onset sepsis, hospitalized...
Open Access DOI:10.23937/2469-5858/1510058
Crystal Y Lumpkins, K Allen Greiner, Christine Daley, Jannette Berkley-Patton, Jinxiang Hu and Shana Palla
Article Type: Research Article | First Published: January 11, 2019
Colorectal cancer (CRC) incidence among low income populations is disproportionate when compared to the general population. Cancer screening studies show religion as a potentially influential factor in individual screening. The present study was an exploratory analysis of religious involvement (RI) among older safety-net clinic patients who participated in 90-day follow up calls during an intervention trial. Results show RI among participants (n = 185) did not significantly predict nor was assoc...
Open Access DOI:10.23937/2469-5858/1510057
Shu-yi Zhou, Ling-ling Zhu and Quan Zhou
Article Type: Research Article | First Published: December 03, 2018
Sporadic studies have investigated the influence of administration time (morning versus evening) on the efficacy and safety of once-daily medications. It is necessary to let clinicians know the developments during the last ten years. Focusing on chronotherapeutic topic, a literature search on randomized controlled trials (RCTs) of oral once-daily cardiovascular agents was conducted using PubMed, Cochrane Library, Scopus and Web of Science from Jan 01, 2008 to Sept 30, 2018....
Open Access DOI:10.23937/2469-5858/1510056
Elif Evrim EKIN, Hulya KURTUL YILDIZ and Muhittin Emre ALTUNRENDE
Article Type: Case Report | First Published: November 03, 2018
A 71-year-old man with low back pain for more than a year, cortical erosion and vertebral cyst formation of L4 vertebral body were diagnosed on lumbar MRI. There was no compression fracture or bone marrow edema. The fusiform unruptured aneurysmatic dilatation of abdominal aorta was seen adjacent to the vertebral cyst (Figure 1 and Figure 2). The vertebral cyst was thought to be associated with abdominal aortic aneurysm (AAA). The aortic wall defect or paraaortic hematoma was not established. Aft...
Open Access DOI:10.23937/2469-5858/1510055
Toosizadeh N, Ehsani H, Taleban S, Golden T, Tirambulo C and Mohler J
Article Type: Research Article | First Published: November 01, 2018
Socio-demographic data, the Charlson Comorbidity Index (CCI), and UEF clinical frailty syndrome classification (non-frail versus pre-frail/frail) were assessed prior to colonoscopy, and acute colonoscopy outcomes were stratified into three severity categories. Logistic regression and ANOVA/ANCOVA were employed. 41% of non-frail had one or more complications, versus 70% of pre-frail/frail group. Those in the pre-frail/frail group had nearly three times the number of acute colonoscopy complication...
Open Access DOI:10.23937/2469-5858/1510054
Viktor Ivanovitch Goudochnikov
Article Type: Review Article | First Published: September 29, 2018
An overview and commentary are presented on the role of stress and glucocorticoids in the pathogeny of age-related psychiatric and neurologic disorders, first of all depressive illness and Alzheimer's disease. The connections of these disorders with senescence-induced changes in bioregulation of hypothamo-pituitary-adrenal axis activity are discussed, focusing attention on biphasic glucocorticoid effects, gender differences, adverse effects of exogenous corticosteroids and the importance of stre...
Open Access DOI:10.23937/2469-5858/1510053
Antonia Kaltsatou, Glen P Kenny and Andreas D Flouris
Article Type: Review Article | First Published: September 29, 2018
The aim of this systematic review was to review the recent literature regarding the effect of heat waves on mortality in elderly adults. A systematic search of the literature, was conducted by two reviewers during March 2018, using three electronic databases (PubMed, Web of Science, and Scopus). The PRISMA guidelines were used for the quality assessment of the published studies. The literature search identified a total of 345 articles, while only 24 studies met the inclusion criteria and were in...
Open Access DOI:10.23937/2469-5858/1510052
Alice Powell, Martin Jude, Stephen Kerr, Jenna Mewburn, Katherine Mohr and Paul Finucane
Article Type: Research Article | First Published: August 10, 2018
The proportion of older people in the Australian population is increasing, heralding a change in how illness presents as well as the profile of people presenting with illness. This changing disease profile is most strikingly observed in conditions which disproportionately affect the old and particularly the oldest old. It is exemplified by stroke which is a leading cause of death and disability in Australia with 70% of stroke patients aged 65 and older....
Open Access DOI:10.23937/2469-5858/1510051
Beth Culross, Mary E Cramer and Shari Terry
Article Type: Case Report | First Published: August 08, 2018
The purpose of this case study is to share an innovative program developed for Registered Nurses (RNs) working in long-term care settings in the Midwest region of the United States and outcomes of the Geriatric Nurse Leadership Academy for Long-Term Care (Leadership Academy). In the United States, the growth of the population over the age of 65 and the need to quality and competent care in long term care has grown exponentially. The Leadership Academy was developed as one component of a research...
Open Access DOI:10.23937/2469-5858/1510050
Li Jiwu, Zhang Ping and Shao Liang
Article Type: Case Report | First Published: June 16, 2018
Coronary artery spasm is a sudden and intense vasoconstriction of single-or multi-vessel coronary artery. It may be triggered by several acute stress. This case reports 72-year-old male with salbutamol inhalation suffer fatal multi-vessel coronary artery spasm. After intracoronary administration of nitroglycerin, coronary artery spasm was relieved. It reminds us to be cautious of β-agonist administration in respiratory patients with coronary artery spasm risk....
Open Access DOI:10.23937/2469-5858/1510049
Vishal Dahya and Jessica Bishop-Royse
Article Type: Research Article | First Published: June 16, 2018
In the decade since the publication of Institute of Medicine reports on patient safety, much remains unknown about the patient-level characteristics that may increase or decrease vulnerabilities to postdischarge adverse events. We reviewed the patient safety literature to determine whether specific sociodemographic groups are vulnerable to postdischarge adverse events. We found substantial inconsistencies in how postdischarge adverse events were defined, which was largely driven by innovations a...
Open Access DOI:10.23937/2469-5858/1510048
Rut Correia, Jose Barroso and Antonieta Nieto
Article Type: Review Article | First Published: June 16, 2018
The study of age-related cognitive changes over the last years reveals a considerable variability in available results. The methodological heterogeneity observed in the aging field can significantly contribute to this observed variability, which creates a confusing scenario for beginners in this topic. The main aim of the present article is to extract a clear depiction of the current state of knowledge about age-related cognitive changes regardless of the methodological approach followed by rese...
Open Access DOI:10.23937/2469-5858/1510047
Erinne N Kennedy, Scott Troppy, Mark Bova and R Monina Klevens
Article Type: Research Article | First Published: June 11, 2018
Overuse of antibiotics has led to adverse events, including bacterial resistance and Clostridium difficile infections (CDI). Antibiotics prescribed by dentists have been implicated in CDI cases. An estimated 10% of outpatient antibiotics in the US are prescribed by dentists. ...
Open Access DOI:10.23937/2469-5858/1510046
Sengul Aycicek G, Cetiner TA, Arik G, Canbaz B, Sumer F, Kara O, Kucuk H and Ulger Z
Article Type: Case Report | First Published: June 06, 2018
Sixty five-year-old female patient admitted to our clinic with complaint of intermittent fever and abdominal pain for forty years. We learned that she has mouth and eye dryness. Laboratory examination revealed elevated levels of inflammatory parameters. In chest X-ray there was reticular appearance....
Open Access DOI:10.23937/2469-5858/1510045
Lydia Tsoutsoubi, Leonidas G Ioannou, Tania Amorim, Georgios I Tsianos, and Andreas D Flouris
Article Type: Short Note | First Published: June 04, 2018
The aim of this study was to investigate the impact of aging and sex on athletic performance during the 7-day Marathon des Sables (MdS) in the Sahara Desert. Anonymous data for age, sex, and average running speed (km/h) for all the athletes who registered in the MdS during the period 2000-2015 were retrieved from the official website of the race and other endurance websites....
Open Access DOI:10.23937/2469-5858/1510044
Juliana Lopes Aguiar, Delmas Luis Freitas Rodrigues, Givago da Silva Souza and Andre dos Santos Cabral
Article Type: Research Article | First Published: June 04, 2018
The perception of position and joint movement, muscular tension and length, adjacent static structures strength and compression such as dermis and epidermis are important variables utilized by central nervous system, both to elaborate and to correct the voluntary motor act, as well as to start motor patterns already set in neural engrams in ontogenetic development of central nervous system....
Open Access DOI:10.23937/2469-5858/1510043
Purwita Wijaya Laksmi, Siti Setiati, Tirza Z Tamin, Pradana Soewondo, Wasilah Rochmah, Nafrialdi and Joedo Prihartono
Article Type: Original Article | First Published: May 21, 2018
Frail elderly has an increased risk of having debilitating health outcomes that lead to poor health-related quality of life (HR-QoL). The central manifestation of frailty syndrome is the muscle functions. The aim of this study was to evaluate the correlation between muscle functions and HR-QoL among pre-frail elderly outpatients....
Open Access DOI:10.23937/2469-5858/1510042
Gizem Yalcin and Abdullah Yalcin
Article Type: Mini Review | First Published: May 02, 2018
Neurodegenerative diseases are progressive disorders that affect central nervous system and gradually worsen over time. Despite many experimental and clinical studies being performed, no effective cure has been found yet. Protein aggregation, excitotoxicity, neuronal death, inflammation, mitochondrial dysfunction, oxidative stress and metabolic syndrome are among the major role players in neurodegeneration. Increasing evidence demonstrates that metabolic syndrome is interrelated with many neurod...
Open Access DOI:10.23937/2469-5858/1510041
Miu Ka Ying Doris
Article Type: Original Article | First Published: April 30, 2018
Research studies have shown that visual ability is of considerable importance for daily living and social functioning. Loss of vision or its limitation can be hazardous to independent living and quality of life. Deficits in vision and the ability to respond to visual cues can cause incorrect sensory inputs and lead to difficulties in perceiving the geographical environment, hazards and moving stimuli....
Open Access DOI:10.23937/2469-5858/1510040
Leonidas G Ioannou, Lydia Tsoutsoubi, Tania Amorim, George Samoutis and Andreas D Flouris
Article Type: Short Note | First Published: March 10, 2018
The relationship between non-thermoneutral zone temperatures with increased mortality in elderly individuals is well established. However, less is known regarding the effect of night-time temperature on mortality in elderly individuals. The aim of this study was to investigate the association between night-time temperature and mortality in elderly people (≥ 70 years) in Cyprus....
Open Access DOI:10.23937/2469-5858/1510039
Warren Connolly, Sinead Healy-Evans, Christine Mc Carthy, Hina Butt, Tom Benicio, Tracey Keating, Dermot Power, Joseph Duggan and Chie Wei Fan
Article Type: Original Article | First Published: February 26, 2018
Nursing Home (NH) residents are frail, functionally dependent and have a high prevalence of dementia. NH residents who attended the Emergency Department present with advanced disease and are more likely to require admission compared to their community-dwelling counterparts....
Open Access DOI:10.23937/2469-5858/1510038
Mark B. Detweiler
Article Type: Commentary | First Published: February 24, 2018
Post-operative cognitive decline (POCD) in the elderly is well known to the anesthesiologists, but others are not as knowledgeable about this complex phenomenon and its causes. POCD is characterized by a slowing of brain processing speed, deficits in memory and executive function, in addition to other neuropsychological domains....
Open Access DOI:10.23937/2469-5858/1510037
Takao Suzuki, Seungwon Jeong, Yasuyuki Arai, Yusuke Inoue, Masahiko Fukuchi, Yoshimichi Kosaka and Hideki Ohta
Article Type: Original Article | First Published: January 26, 2018
The present study focused on "fever" as an indicator or surrogate of aspiration pneumonia, which is the most commonly encountered event in home medical care and frequently requires a decision of whether to continue or discontinue (admission to hospital) home medical care. We compared the outcome of a group that continued to receive home medical care during and after a fever-related event and a group that discontinued home medical care and was hospitalized. Our analysis showed that loss of the ab...
Open Access DOI:10.23937/2469-5858/1510036
Article Type: Review Article | First Published: December 01, 2017
Melatonin is a highly pleiotropic regulator molecule that influences numerous functions in many cell types. Its actions comprise direct and circadian oscillator-mediated effects. The levels of circulating melatonin typically decline in the course of aging....
Open Access DOI:10.23937/2469-5858/1510035
Aline Siqueira Fogal, Sylvia do Carmo Castro Franceschini, Giana Zarbato Longo and Andréia Queiroz Ribeiro
Article Type: Research Article | First Published: October 30, 2017
Body Mass Index (BMI) is an easily measurable indicator of body fat and with low cost. However, as an indicator of risk of development of chronic diseases in the elderly, it has limitations, as it does not reflect mainly the regional distribution of fat that occurs with the aging process....
Open Access DOI:10.23937/2469-5858/1510034
Andrew A Lawson, John H Mensher, Hendrika W Meischke and Elizabeth A Phelan
Article Type: Opinion | First Published: October 16, 2017
As the world population ages and older adults comprise a growing segment of the population, the public health community must formulate plans and work diligently to reduce health risks that compromise independence and quality of life for this age group....
Open Access DOI:10.23937/2469-5858/1510033
Ellen Cristina de Sousa e Silva Araujo, Valéria Pagotto and Erika Aparecida Silveira
Article Type: Research Article | First Published: August 31, 2017
Bone health and its relationships with several health outcomes of adults and elderly have been in the spotlight of recent research, as its consequences affect morbimortality. In literature, there is evidence that decreases in Bone Mineral Density (BMD) are due to the natural ageing process for both sexes, however more prevalent for women, with consequences such as increased risk of fractures, falls and incapacities in the female group....
Open Access DOI:10.23937/2469-5858/1510032
Pakzad S, Bourque P, Feldman H and Fallah N
Article Type: Research Article | First Published: August 31, 2017
Rapid demographical change in developing countries is much more than a transition. It is about increased health care utilization, dramatic vulnerability related to health changes, higher risk of institutionalization, and mortality. Chronological age is a very important factor in the aging process; however, people of the same chronological age are often dramatically different in their health, level of activity, quality of life, and survival....
Open Access DOI:10.23937/2469-5858/1510031
Ashwini Wagle, Clarie Hollenbeck and Jesus Dimas
Article Type: Research Article | First Published: July 15, 2017
Limited research has been conducted in the United States in which exposure to solar UVB light is studied in a natural setting as a strategy to improve vitamin D status in institutionalized older adults....
Open Access DOI:10.23937/2469-5858/1510030
Kilby P Osborn IV, Stephanie Nothelle, James E Slaven, KiannaMontz, SiuL Hui and Alexia M Torke
Article Type: Research Article | First Published: June 12, 2017
When older adults are hospitalized they have an increased risk of adverse outcomes and high healthcare utilization. In 2010 adults aged 65 and older made up 73% of hospital deaths compared to 27% for those less than 65 years of age. In 2007 the average Length of Stay (LOS) for patients 65 and older was 5.6 days compared to 5.1 days for those 45 to 64....
Open Access DOI:10.23937/2469-5858/1510029
Tania Amorim, Leonidas G Ioannou, FaniSpapi and Andreas D Flouris
Article Type: Research Article | First Published: June 09, 2017
Climate change is estimated to affect global temperature, leading to an increased number of extreme weather events across the globe. Mortality during these extreme events has been shown to be increased. Indeed, the association between extremely low or high ambient temperatures and daily deaths across several regions of the world has been extensively reported....
Open Access DOI:10.23937/2469-5858/1510028
Mitsuhiro Kamimura, Atsuto Mouri, Tatsuya Ibe, Munehisa Hukusumi and Yoichiro Hamamoto
Article Type: Letter to Editor | First Published: June 02, 2017
Aspiration is the main cause of pneumonia in the elderly, especially in those with cerebrovascular disease. Angiotensin-Converting Enzyme (ACE) inhibitors are known to prevent aspiration, especially in Asian populations, and their suggested mechanism of action involves the promotion of the release of substance P from the glossopharyngeal and vagal nerves, resulting in an improvement in impaired swallowing processes and the cough reflex....
Open Access DOI:10.23937/2469-5858/1510027
Jianfeng Luo, Hanzhang Xu, Ye Zhang, Naiqing Zhao and Bei Wu
Article Type: Research Article | First Published: May 21, 2017
Emerging large number of patients with chronic diseases, present special challenges for modern health system. Self-treatment may be an alternative approach to meet the healthcare demand, and currently of great interest in many countries. However, whether self-treatment can decrease the use of formal health care, especially outpatient visits, is still not clear. No empirical study has been conducted to examine the relationship between self-treatment and outpatient visits of individuals with chron...
Open Access DOI:10.23937/2469-5858/1510026
V Dougoud Chauvin, MG Fradley, L Chen, J Kim, CM Walko, M Sehovic and M Extermann
Article Type: Research Article | First Published: May 18, 2017
The treatment of choice for newly diagnosed patients with advanced Diffuse Large B Cell Lymphoma (DLBCL) is R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone). However older patients frequently have concomitant cardiac comorbidities that preclude the use of these agents....
Open Access DOI:10.23937/2469-5858/1510025
Ma Teresa Ortega Majan, Diego Judez Legaristi and Antonio Hernandez Torres
Article Type: Research Article | First Published: April 21, 2017
Because there are mineral-rich medicinal waters in natural thermal spas. Their mechanical, thermal and psychotropic properties should be harnessed and the transmineralisation resulting from absorption through the skin of the ions they contain is fundamental. The main objective of this study was to determine whether the possible improvement in quality of life following balneotherapy can be maintained for at least two months after undergoing various thermal treatments....
Open Access DOI:10.23937/2469-5858/1510024
Maria-José Molina-Garrido, Carmen Guillén-Ponce and Alfonso Muriel
Article Type: Protocol Study | First Published: March 09, 2017
This study aims to identify the presence of frailty in elderly cancer patients by analysing their functional reserve. In order to do so, a prospective study of oncological patients over the age of 70 years, assessed on an outpatient basis at the Hospital Virgen de la Luz of Cuenca has been conducted, and data regarding functional reserve at various levels in the body have been collected....
Open Access DOI:10.23937/2469-5858/1510023
Pakzad S, Bourque P, Tahir L, Bhalla D, French C, Savoie V and Sepehry AA
Article Type: Research Article | First Published: March 03, 2017
Evidence shows that subjective memory complaints (SMCs) could represent an important therapeutic period for people at risk for sustaining future cognitive decline, but current knowledge on the behaviour profile of the SMCs is scarce. Thus, to better understand the SMCs' help-seeking behaviour from health care professionals, a cross-sectional study using a correlational and comparative model was implemented....
Open Access DOI:10.23937/2469-5858/1510022
Wolfgang Trapp, Robert Meyrer, Goran Hajak and Stefan Lautenbacher
Article Type: Short Communication | First Published: February 16, 2017
Little is known whether tests used for the diagnosis of dementia syndromes are sensitive to time of day effects. In a sample of 145 participants, no such effect (test administration either in the morning from 9.30 to 11.30 a.m. or in the afternoon from 2.30 to 4.30 p.m.) could be found for most subtests of a neurocognitive test battery (CERAD-Plus) used for the detection of dementia syndromes....
Open Access DOI:10.23937/2469-5858/1510021
Michael J Phelan, Ruth A Mulnard, Daniel L Gillen and Steven S Schreiber
Article Type: Research Article | First Published: February 14, 2017
Disease-modifying treatments for Alzheimer's disease (AD) are currently unavailable and are the focus of an intensive research effort. We found vitamin B3, nicotinamide (NA), to significantly reduce pathology and improve behavior in AD transgenic mice. These results led us to conduct a double-blind, placebo-controlled randomized clinical trial of NA in mild to moderate AD....
Open Access DOI:10.23937/2469-5858/1510020
Wilbert S Aronow
Article Type: Editorial | First Published: October 17, 2016
The target SBP reached was 150 mmHg, and the lowest SBP reached was 143 mmHg. Median follow-up was 1.8 years. Compared to patients randomized to placebo, patients randomized to antihypertensive drug therapy had a 30% reduction in fatal or nonfatal stroke, a 39% reduction in fatal stroke, a 21% reduction in all-cause mortality, a 23% reduction in cardiovascular death, and a 64% reduction in heart failure....
Open Access DOI:10.23937/2469-5858/1510019
Regina Girones and Jose Luis Monroy
Article Type: Research Article | First Published: October 15, 2016
The optimal chemotherapy regimen to use with radiotherapy in stage III locally-advanced non-small-cell lung cancer (LA-NSCLC) is unknown. Considering the lack of clear data and guidelines for elderly patients, we designed this review to examine patterns of care for elderly patients with LA-NSCLC with a regional hospital database....
Open Access DOI:10.23937/2469-5858/1510018
Samantha Pereira Araujo, Thiago Souza Veiga Jardim, Ana Luiza Lima Sousa, Nayara Cristina Freitas e Silva, Weimar Kunz Sebba Barroso de Souza and Paulo Cesar Brandao Veiga Jardim
Article Type: Research Article | First Published: September 26, 2016
Blood pressure control and nutritional status did not influence health-related quality of life of very elderly hypertensive. Men have a better quality of life related to the physical aspects, and physically active individuals have a better health-related quality of life related to functional capacity. ...
Open Access DOI:10.23937/2469-5858/1510016
Sarah Pakzad, Paul Bourque, Lise Gallant, Denise Donovan and Amir A Sepehry
Article Type: Original Article | First Published: September 15, 2016
Aging is a major risk factor for dementia and evidence shows that community-dwelling elderly are underdiagnosed and undertreated. Family physicians (FP), as gatekeepers, play a crucial role in the diagnosis and management of dementia; hence an understanding of their perspective during this process is important. Currently, few studies have examined the Canadian FPs perspective towards dementia diagnosis using a validated questionnaire. Thus, a questionnaire to appraise FPs practices in the diagno...
Open Access DOI:10.23937/2469-5858/1510015
Article Type: Case Series | First Published: September 12, 2016
Background and purpose: Post-stroke mania is thought to be rare, and has been described after lesions in the territory of the left medial cerebral artery, biparietal cortex, and the left putamen. Methods: Case-study methodology was used to identify similarities and difference among six cases of post-stroke mania in a rural, community hospital over 1 year....
Open Access DOI:10.23937/2469-5858/1510014
David Bradley and Willa Hsueh
Article Type: Review Article | First Published: September 08, 2016
In the older patient population, rates of Type 2 Diabetes (T2D) and obesity are reaching epidemic proportions. In fact, older patients will soon constitute the majority of patients with T2D in most developed countries. The higher prevalence of T2D in older individuals is seen in both men and women and across racial and ethnic groups. However, certain ethnic groups are disproportionately affected and successful strategies must account for these fundamental differences....
Open Access DOI:10.23937/2469-5858/1510013
SR Gnanenthiran, A Yong and HC Lowe
Article Type: Brief Review | First Published: June 21, 2016
An 86-year-old independent but frail woman living at home, presented with recurrent chest pain and pulmonary oedema. Her past history included recurrent medically managed non ST elevation myocardial infarction, heart failure and steroid responsive idiopathic thrombocytopenia (ITP). The electrocardiogram demonstrated lateral ST depression and T wave inversion. High sensitivity troponin T rose from 39 ng/L to 65 ng/L. Echocardiogram demonstrated normal left ventricular ejection fraction and hypoki...
Open Access DOI:10.23937/2469-5858/1510012
Yaar Aga, Ximena Marincic, Christian Marin y Kall, Peter de Jaegere and Eduardo De Marchena
Article Type: Research Article | First Published: April 01, 2016
Transcatheter Aortic Valve Replacement (TAVR) has emerged as an alternative treatment modality for patients with severe aortic stenosis (AS) who are at high or extreme risk for surgical aortic valve replacement (SAVR). Previous studies have shown that TAVR results in substantial reductions in symptoms and mortality. Despite these health benefits, the assessment of quality of life (QOL) remains critical in these patients who often express quality of life over quantity of life....
Open Access DOI:10.23937/2469-5858/1510011
Paula Martinez Santos, Elena Batlle Lopez, Isidre Vilacosta, Beatriz Sanchez Sauce, Elena Espana Barrio, Julia Jimenez Valtierra, Raquel Campuzano Ruiz, Ma Dolores Martin Rios
Article Type: Original Article | First Published: February 27, 2016
Albumin serum levels and N-terminal pro-brain natriuretic peptide (NT proBNP) have shown to be useful in predicting outcome in patients with heart failure (HF) and systolic dysfunction. Carbohydrate antigen 125 (CA 125) has also been associated to a higher risk of mortality and rehospitalization in patients with HF and impaired left ventricular systolic function. The aim of this study was to evaluate the prognostic role of these biomarkers among acute decompensated HF with preserved ejection fra...
Open Access DOI:10.23937/2469-5858/1510010
An Examination of Self Perceptions of Nursing Assistants and the Effectiveness of Nursing Education Intervention to Improve Nursing Assistants' Knowledge of Mental Health Issues in an Elderly Population
Article Type: Review Literature | First Published: February 27, 2016
In 2014, an estimated 5.3 million people in the United States were diagnosed with Alzheimer's Disease (AD), a degenerative form of dementia generally associated with aging process which begins with memory loss and leads to disorientation, impaired judgment, behavioral changes, and difficulties in speaking, walking, and swallowing in later stages. As Americans age, the number of persons with this condition is anticipated to rise to 16 million by 2050....
Open Access DOI:10.23937/2469-5858/1510007
Golnar Alamdari and Luciana Lagana
Article Type: Research Article | First Published: December 31, 2015
In a high quality research study conducted earlier this year, Outcalt, Kroenke, Krebs, et al. emphasized that depression and post-traumatic stress disorder are often present in individuals living with chronic pain and typically have negative consequences on both the experience of pain and health outcomes, yet, the specific nature of the pain-depression-PTSD link remains unclear. This is especially applicable to older adults, a population that has seldom been studied on this topic....
Open Access DOI:10.23937/2469-5858/1510009
Beth Fairfield, Alberto Di Domenico, Rocco Palumbo and Nicola Mammarella
Article Type: Research Article | First Published: February 01, 2016
The aim of the present study was to examine serial visual processing of facial emotion in a group of younger and older adults. Participants performed a visual serial search task in which they searched displays of schematic faces with positive, negative or neutral mouth expressions. Our findings show that older adults did particularly well when detecting positive target faces....
Open Access DOI:10.23937/2469-5858/1510008
Michael David Richter and Leslie Dubin Kerr
Article Type: Review Article | First Published: January 18, 2016
Diffuse systemic sclerosis typically presents in persons aged 30-50 years. Although it is not uncommon to encounter the limited form of the disease in persons over the age of 65, diffuse disease in this age group is considered to be uncommon. Thus it is not considered as a diagnostic possibility in older adults who develop respiratory or gastrointestinal complaints....
Open Access DOI:10.23937/2469-5858/1510006
William F Rayburn, Greta B Raglan, Carla J Herman and Jay Schulkin
Article Type: Research Article | First Published: December 02, 2015
The population of older Americans is expected to represent 20 percent of the total U.S. population in the next 50 years, and older women will comprise the majority of that group. Thus, health care needs of this group are and will continue to be an increasing concern. Several factors such as diversity of the population, distinguishing between normal aging and disease, and the impact of socioeconomic concerns on physical and mental health are important for developing preventive and treatment strat...
Open Access DOI:10.23937/2469-5858/1510005
Lili Zhang, Xiaowei Liu, Bailing Wang, Qing Xu, Jianzhong Zhu, Feng Zhang and Chunhui Jin
Article Type: Communication | First Published: September 14, 2015
Mild cognitive impairment (MCI) is defined as the symptomatic predementia stage, characterized by cognitive impairment that is not severe enough to influence the usual activities of daily living. MCI is suggested to be a transitional state between healthy aging and clinically probable Alzheimer's disease (AD). Previous studies have identified that single nucleotide polymorphisms (SNPs) in the sortilin-related receptor, L (DLR class) A repeats containing (SORL1) gene are associated with amnestic ...
Open Access DOI:10.23937/2469-5858/1510004
Xin Qi Dong and Ge Li
Article Type: Original Article | First Published: September 05, 2015
Elder abuse, also referred to as elder mistreatment or elder maltreatment, is an important public health and human rights issue. The prevalence of elder abuse ranges from 2.2% to 61.1% around the world. The 2008 US National Elder Mistreatment Study suggests that more than 10% of the community-dwelling aging population reported elder abuse or potential neglect in the past year. Existing literature has shown that elder abuse may result in psychological distress, increased morbidity and mortality i...
Open Access DOI:10.23937/2469-5858/1510003
Joseph O. Nnodim and Raymond L. Yung
Article Type: Research Article | First Published: September 02, 2015
Balance impairment is common among older adults and estimates of its prevalence range between 20 and 50%. In basic terms, loss of balance occurs when the center of mass (CoM) falls out of alignment with the base of support (BoS). With about two-thirds of body mass about two-thirds of body height above a relatively narrow BoS, human bipedal stance and gait are inherently low in stability. Further, the BoS is about halved when standing on one leg, adding to the potential instability. It is therefo...
Open Access DOI:10.23937/2469-5858/1510002
Terminal Care in Older Patients in Hospital: Development of a Quality Indicator Set and its First Application in a Retrospective Comparison of Patients Treated in an Acute Geriatric Unit and a Palliative Care Unit of a Belgian University Hospital
Annelies Cools, Delphine Vaneechoutte, Nele Van Den Noortgate, Karen Versluys, Martine De Laat, Mirko Petrovic and Ruth Piers
Article Type: Research Article | First Published: August 26, 2015
During the last decades, there has been growing interest in high quality end-of-life care for the geriatric patient. This can be explained by the aging of the population, which leads to an increased number of frail, older patients who die in hospitals as a result of one or more chronic condition(s). The quality of end-of-life care for the geriatric patient is not optimal, characterized by inadequately treated symptoms and poor communication between health care professionals, patients and their f...
Open Access DOI:10.23937/2469-5858/1510001
Ruijia Chen and Xin Qi Dong
Article Type: Original Research Article | First Published: August 26, 2015
EM was first identified by British gerontologists in 1975 using the term 'granny battering', but it is not until recently that researchers have rigorously examined the issue. Epidemiologic research documents that more than one in ten older adults suffered from some kinds of mistreatment in the U.S, making it one of the most significant public health and human rights issues. EM is likely to impose an enormous burden on individual, families, and society....
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