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Journal of
Geriatric Medicine and Gerontology ISSN: 2469-5858

Citation

Toosizadeh N, Ehsani H, Taleban S, Golden T, Tirambulo C, et al. (2018) Screening Colonoscopy Adverse Events in Aging Adults: Does Frailty Matter?. J Geriatr Med Gerontol 4:055. doi.org/10.23937/2469-5858/1510055

Copyright

© 2018 Toosizadeh N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2469-5858/1510055

Screening Colonoscopy Adverse Events in Aging Adults: Does Frailty Matter?

Toosizadeh N1,2,3, Ehsani H1,3, Taleban S1,4, Golden T1,5, Tirambulo C1 and Mohler J1,2,3*

1Arizona Center on Aging, College of Medicine, University of Arizona, Tucson, Arizona, USA

2Division of Geriatrics, General Internal Medicine and Palliative Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA

3Division of Biomedical Engineering, College of Engineering, University of Arizona, Tucson, Arizona, USA

4Division of Gastroenterology & Hepatology, College of Medicine, University of Arizona, Tucson, Arizona, USA

5Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona, USA

Abstract

Screening colonoscopy is beneficial in screening for colorectal cancer, though it is not without risks, which increase with increasing age. The objectives of this prospective feasibility and outcomes study was to assess the effectiveness of the upper-extremity frailty (UEF) test to risk stratify adults ≥ 50 years of age undergoing routine screening colonoscopy.

Socio-demographic data, the Charlson Comorbidity Index (CCI), and UEF clinical frailty syndrome classification (non-frail versus pre-frail/frail) were assessed prior to colonoscopy, and acute colonoscopy outcomes were stratified into three severity categories. Logistic regression and ANOVA/ANCOVA were employed.

41% of non-frail had one or more complications, versus 70% of pre-frail/frail group. Those in the pre-frail/frail group had nearly three times the number of acute colonoscopy complications (OR 2.84, p = 0.01) when compared to the non-frail. Chronological age, and comorbidity score (CCI) failed to predict complication outcomes. UEF frailty was useful in predicting acute complications in screening colonoscopy.