Journal of

Dermatology Research and TherapyISSN: 2469-5750

Current Issue

 Open Access DOI:10.23937/2469-5750/1510078

Albumin, Important Therapy & When to Use It in Ten Patients (Adult & Child): Case Report

Nathasia and Sukmawati Tansil Tan

Article Type: Case Report | First Published: February 03, 2020

Toxic epidermal necrolysis (TEN) is a life-threatening drug reaction that requires immediate medical treatment. Mortality due to TEN cases is quite high until now and the main cause reported is multiple organ dysfunction syndrome. A 7-year-old child, was diagnosed TEN with 86% blistered skin, after receiving Metampiron. Given 20% albumin 50 ml from the first day treated until 20 days, also fluid resucitation, steroids, antibiotics, vitamin C, neurobion, paracetamol, antihistamines, oral hygiene,...

 Open Access DOI:10.23937/2469-5750/1510077

Comparative Study of the Online Over-The-Counter Hair Loss Products

Abdullah Alyoussef

Article Type: Original Article | First Published: January 04, 2020

There are tremendous amount of the overthe- counter (OTC) hair loss products available online and widely purchase all over the world by many consumers. We conducted this study to evaluate some popular and widely used OTC hair loss products that are introduced by famous online retailer websites. Most of hair loss products are natural products, vitamins, minerals, amino acids and proteins. The products found in the top sellers are different between the online retailers regarding their type, side, ...

 Open Access DOI:10.23937/2469-5750/1510076

The Role of the CD57+ T-Lymphocytes in Various Malignancies and Their Potential Contribution to the Increased Frequency and Aggressiveness of Cscc in OTR

Shaikah Al-Aojan

Article Type: Mini Review | First Published: December 30, 2019

Organ transplant recipients (OTR) have 100-fold increased risk for cutaneous squamous cell carcinoma (cSCC) compared to the general population. Modified immune surveillance mechanisms may contribute to the perceived differences in incidence, clinical behavior and increased aggressiveness of cSCC in OTR. It could also provide some insight into the pathogenesis of cSCC in various disorders characterized by low immunity such as HIV, hematological malignancies and immune-mediated inflammatory disord...

 Open Access DOI:10.23937/2469-5750/1510075

A New Way to Inhibit IL-17 in Psoriasis: Real-Life Use of Brodalumab Goes Beyond Clinical Trials Expectations

Mario Valenti, Paola Facheris, Giulia Pavia, Alessandra Narcisi, Riccardo Borroni and Antonio Costanzo

Article Type: CASE SERIES | First Published: December 30, 2019

Psoriasis is a common inflammatory skin disease that is estimated to affect about 2-4% of the population, with rates varying across ethnic groups and geographical regions. Biotechnological (more commonly called biologic drugs) drugs have shown great results in treating severe forms of psoriasis. Biologic agents that specifically block the IL-17 pathway have shown promising results with regard to efficacy and safety. Specific IL-17 inhibitors are represented by Secukinumab and Ixekizumab, fully h...

 Open Access DOI:10.23937/2469-5750/1510062

Seborrheic Keratoses of the Penis: About a Rare Case

Salma Salim, Jamila Bouhelab, Asmae Benzekri and Badredine Hassam

Article Type: Case Report | First Published: September 26, 2018

Seborrheic keratoses (SK) are very common benign epidermal tumors. Their pathogenesis has been detected already in 2006 and includes several aetiological factors. The participation of human papilloma virus (HPV) is being discussed. SK of the penis is extremely rare and may be misdiagnosed. Histopathology will help in the diagnosis. Seborrheic keratoses (SK) are very common benign epidermal tumors. Their pathogenesis has been detected already in 2006 and includes several aetiological factors. The...

 Open Access DOI:10.23937/2469-5750/1510061

Resveratrol, Blueberry, Cranberry and Raspberry Exhibit Protection Effect to Photodamaged Hair

Julia de Souza Gomes, Marina Silva Rita, Joao Marcos da Cunha Altomare, Nadia Rezende Barbosa Raposo, Marcos Antonio Fernandes Brandao and Hudson Caetano Polonini

Article Type: RESEARCH ARTICLE | First Published: September 07, 2018

When hair is exposed to the sun there may occur protein degradation, which alters its physical appearance. Thus, beneficial hair adjuvants with addition of natural sunscreens are sought for cosmetics development. In this study, we developed hair conditioning products containing blueberry, raspberry, cranberry and resveratrol in different proportions, incorporated into TrichoCond®. In vitro photoprotection capacities of the products and cystine content of the hair samples after treatments were d...

 Open Access DOI:10.23937/2469-5750/1510060

T/NK Lymphoma Nasal Type with Fatal Outcome

Youssef Zemmez, Jaouad El Azhari, Badreddine Hassam and Nadia Ismaili

Article Type: Case Report | First Published: August 23, 2018

T/NK-cell lymphoma of nasal-type was described in 1933 as a malignant medio-facial granuloma. The diagnosis of this rare condition is clinical and immunohistopathological. We report an original case of cutaneous T/NK lymphoma of the nasal type revealed by cutaneous ulcerations....

 Open Access DOI:10.23937/2469-5750/1510059

Management of Keloid Scars: Surgical Versus Medical Therapy

Abdulhadi Jfri and Ali Alajmi

Article Type: Research Article | First Published: August 04, 2018

Keloids are benign fibroproliferative tumors that occur as a response to any kind of injury to the skin to susceptible individuals. Keloid tissue extends beyond the margins of the wound which distinguish it from hypertrophic lesions. Keloids tend to grow symptomless, but still can often cause pain or itching. They have a functional, aesthetic, or psychosocial impact on patients, as highlighted by quality-of-life studies....

 Open Access DOI:10.23937/2469-5750/1510058

Histomorphometric Evaluation of Intraepithelial Papillary Capillaries in Oral Lichen Planus: A Histopathological Study

Kazuhiro Hasegawa, Hiroyuki Sakamaki, Masahiro Higuchi, Masaaki Suemitsu, Chieko Taguchi, Ko Ito, Miyuki Morikawa, Tadahiko Utsunomiya, Toshirou Kondoh and Kayo Kuyama

Article Type: Original Article | First Published: July 30, 2018

Definitive diagnosis of oral lichen planus (OLP) is important for planning treatment. The problems and difficulties of diagnosing OLP based on histopathological features were showing inter- and intra-observer variability. In terms of pathological diagnosis on OLP, microvascular appearance was not highly valued. Comparative histomorphometric analysis of intraepithelial papillary capillary loops (IPCLs) of OLP was performed to investigate the potential for use as diagnostic criteria....

 Open Access DOI:10.23937/2469-5750/1510057

Psoriasiform Sarcoidosis Presenting in Pregnancy and Treatment Considerations

Christian A Albornoz, Jordan V Wang and Matthew Keller

Article Type: Case Report | First Published: July 04, 2018

Cutaneous sarcoidosis is a common presentation for patients with sarcoidosis. Rarely, patients can present with psoriasiform lesions mimicking chronic plaque psoriasis. Here, we present a case of psoriasiform sarcoidosis in a pregnant patient. Pregnancy represents a unique challenge to systemic treatments if topical management fails. Tumor necrosis factor alpha inhibitors warrant special consideration during pregnancy....

Volume 4
Issue 2