Smoking Habit in Adult Population from Maracaibo City, Venezuela
Valmore Bermúdez1, Edgar Miquilena1, Juan Salazar1*, Robys González1, Luis Carlos Olivar1, María José Calvo1, Roberto Añez1, José R. Rivas-Ríos1 and Joselyn Rojas1,2
1Endocrine and Metabolic Disease Research Center "Dr. Felix Gomez", University of Zulia, Venezuela
2Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, USA
*Corresponding author: Juan Salazar, MD, Endocrine and Metabolic Research Center "Dr. Felix Gomez", School of Medicine, University of Zulia, Maracaibo, Venezuela, E-mail: firstname.lastname@example.org
Int J Respir Pulm Med, IJRPM-3-061, (Volume 3, Issue 4), Research Article; ISSN: 2378-3516
Received: July 25, 2016 | Accepted: November 03, 2016 | Published: November 06, 2016
Citation: Bermúdez V, Miquilena E, Salazar J, González R, Olivar LC, et al. (2016) Smoking Habit in Adult Population from Maracaibo City, Venezuela. Int J Respir Pulm Med 3:061. 10.23937/2378-3516/1410061
Copyright: © 2016 Bermúdez V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The aim of this study was to determinate the epidemiology of smoking in adults from Maracaibo.
Materials and methods: A descriptive, cross-sectional research study, framed in the study Prevalence of Metabolic Syndrome in Maracaibo city conformed by 2,212 adults of both genders; based on the medical information the individuals were classified in smokers, non-smokers and former smokers. Quantitative variables were expressed as medians and qualitative variables as absolute and relative frequencies, using χ2 for significance and Z test for difference of proportions.
Results: In general analysis 14.8% were smokers, 15.4% were former smokers, and the remaining individuals were non-smoking (69.8%). Cigarette is the most prevalent tobacco derivative (98.7%). The higher proportion of cigarette smokers are male (χ2 = 36.70; p < 0.01), however the proportion of women between 40-59 years matched the men's proportion (χ2 = 143.20; p < 0.01). Smoking was associated with marital status (χ2 = 45.67; p < 0.01), academic status (χ2 = 17.07; p = 0.01), occupation (χ2 = 32.04; p < 0.01), type of employment (χ2 = 138.25; p < 0.01) alcohol consumption (χ2 = 99.15; p < 0.01) and Body Mass Index Classification (χ2 = 38.5; p < 0.01).
Conclusion: Smoking is an important public health issue in our population, associated with certain sociodemographic and metabolic conditions, additional studies are needed to evaluate, in a multi-variant context, the individual influence of the associated factors.
Smoking, Consumption patterns, Smokers, Former smokers, Employment status
Tobacco consumption is one of the leading causes of preventable death worldwide, representing approximately 6 million deaths per year [1,2]. Forward-looking statements are even more alarming estimating that by 2030 the annual deaths attributable to smoking will increase to 8 million . The harmful effects of smoking in the human body depends directly on the amount of cigarettes and timing of smoking , as well as the changes in lifestyle of those who smoke , with special influence on mortality from chronic and degenerative diseases such as cervical cancer , lung  and cardiovascular diseases , which represent 63% of all deaths worldwide [3,6].In this way, it produces a significant economic impact due to public spending demand and according to the latest report, it had increased to more than two billion dollars by 2009 .
The understanding of the deleterious effects of tobacco over smoker's health has led to some measures that help controlling this habit. The WHO Framework Convention Tobacco Control (FCTC)  has become one of the most rapidly embraced treaties in the history of the United Nations, as the first step in the global fight against the epidemic of smoking. In this treaty are summarized all the measures to stop this epidemic. In accordance to those measures our country has increase tobacco prices by higher taxes as one of the most effective individual ways to reduce the tobacco consumption and encourage consumers to quit. In addition, they have been banned certain forms of advertising and promotion, however direct advertising in national print media and internet outlets are allowed .
In despite of these efforts, the Pan American Health Organization reported in 2011 that in Venezuela 33.9% of the population over 15-years-old are smokers , 61.6% represented by males and 38, 4% by females. While these statistics are similar to the prevalence of smoking reported in the US (29%), it is considerably higher than those reported by the organizations in Latin American countries like Mexico (16%) and Colombia (17%). These reports lead to the implementation of tobacco smoke exposures law in public and closed work places throughout the country, creating completely smoke-free environments . Although smoking is still a public health problem in our country, epidemiological data in Maracaibo is limited. Therefore, the aim of this study was to determine the prevalence of smoking and the associated sociodemographic characteristics in adults from Maracaibo.
Materials and Methods
Individuals were included in the study after being consented, gathering a complete medical history, physical examination and obtained blood samples by a trained staff. Every procedure was approved by the ethics committee of the Endocrine and Metabolic Diseases Research Center "Dr. Felix Gomez".
The Maracaibo City Metabolic Syndrome Prevalence Study was a cross sectional, randomized and multistage sampling study which aimed to identify and assess the epidemiological behavior of metabolic syndrome and its associated risk factors in 2,230 individuals over 18 years . For the analysis of smoking habits, 9 individuals were excluded due to unclear information about age of onset or smoking time consumption, resulting in a preliminary sample of 2,221 individuals. After reviewing the use of tobaccos derivatives, it was found that only 9 individuals (0.4%) consumed cigars which were excluded from statistical analysis, ending with a final sample of 2,212 subjects.
During collecting information, the main demographic characteristics and ethnic group were asked. Marital status was classified into five categories: single, married, cohabiting, divorced and widowed. The employment condition was classified into two categories: employed and unemployed. The educational status was classified as: a) unlearned: individuals without learning b) elementary school: those with basic and middle education c) high school d) College/University: those who had technical, colleges or university study or degree. Socioeconomic status was classified according to the categories proposed by Mendez-Castellano . This tool allows stratification of the population according to four variables: occupation of the head of household, educational level of the subject's parents, income source, and housing conditions. Each of these items is rated in a Likert-type scale from 1 to 5 (1 representing the best possible scenarios and 5 the worst). The scores for each item are tallied into a total integrated score ranging from 4 to 20 points, categorized as follows: Stratum I or High Class (4-6 points); Stratum II or Middle-High Class (7-9 points); Stratum III or Middle Class (10-12 points); Stratum IV or Relative Poverty (13-16 points), and Stratum V or Critical Poverty (17-20 points).
Blood pressure (BP) was taken with individual sitting down with their feet on the floor, determined through the auscultatory method with a calibrated mercury sphygmomanometer, identifying Korotkoff's phases I and V systolic and diastolic BP, respectively. Results were classified by the Eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-8) guidelines .
A bioelectric scale was used to obtain weight (Tanita, TBF-310 GS Body Composition Analyzer, Tokyo, Japan). Height was measured using a calibrated metric measurement tape, with the subject standing up barefoot. Body Mass Index (BMI) was calculated with the following formula: [weight/height2], according to their BMI, subjects were sorted in 3 categories: (a) BMI ≤ 24.9; (b) 25-29.9; and (c) ≥ 30 kg/m2 .
Tobacco habit description
We inquired about the use of cigarettes, cigars, pipe and chewing tobacco requested in detail the age of onset, frequency, time consumption and time without smoking. The frequency of cigarette consumption was express in cigarettes per day  and the others variables were expressed in years. The pattern of cigarette smoking was defined as  : a) non-Smoker to every individual who denied their consumption or have consumed < 100 cigarettes during their lifetime, b) Smoker to those individuals who have consumed ≥ 100 cigarettes during their life, or if tobacco consumption has been suspended for a period not exceeding 1 year prior the study, c) Former Smoker who has consumed a number ≥ 100 cigarettes during their lifetime, but has stopped the habit for a time period ≥ 1 year prior to the study.
The International Physical Activity Questionnaire (IPAQ) was used as a method to quantifying physical activity [17,18], taking into account the following domains: work, transportation, household/gardening and leisure-time. Through this questionnaire was determined the consumed metabolic equivalents (METS) calculated according to the average result of time for each activity and the sum of these 4 scores were formulated.
Based on the total score of METs/min/week obtained, those with 0 METs per domain were considered physically inactive. Individuals with some degree of physical activity (≥ 1 MET) were categorized into quintiles according to gender, obtaining a total of six categories: physical inactivity (METs = 0), very low (Q1), low (Q2), moderate (Q3), high (Q4) and very High (Q5).
For the assessment of alcohol consumption, individuals were asked about the amount of alcohol intake monthly, defining drinkers as those who consumed at least one drink per month. These individuals were asked to report an approximate average amount and frequency of alcohol intake. After this estimation, a current consumer was defined as the consumption of ≥ 1 gram (g) of alcoholic beverages per day .
The metabolic syndrome was defined by the criteria from the IDF/NHLBI/AHA/WHF/IAS/IASO-2009 consensus , whereas subjects having the following characteristics were operatively classified as having Type 2 diabetes mellitus: a) a previously established diagnosis and b) those without personal history but with fasting glucose ≥ 126 mg/dL. By the other hand, non-diabetic subjects were classified as follows: a) norm glycemic: individuals with fasting glucose < 100 mg/dL; and b) impaired fasting Glucose: fasting glucose in the range of 100-126 mg/dL .
Data were evaluated by using the Statistic al Package for Social Sciences (SPSS) v.20 (SPSS Inc. Chicago, IL). Quantitative variables were expressed as median (p25-p75), being compared using the Mann-Whitney U test (when 2 groups were compared) or Kruskal-Wallis (when 3 or more groups were compared). The qualitative variables were expressed as absolute and relative frequencies, using Chi-square and proportions Z test to determine the respectively association and differences of proportions, being statistical significant when p < 0.05.
Prevalence of tobacco derivatives consumption
The preliminary sample consisted of 2,221 individuals, distributed in 1170 women (52.7%) and 1051 men (47.3%); whose average age were 38-years-old (25-51 years old). From this sample, 30.1% (n = 668) reported having smoked cigarette in their lives; while consumption of cigars represented only 0.4% (n = 9). After excluding individuals who consumed only cigars, the final sample was 2,212 individuals (52.7% women and 47.3% men), of which 69.8% were non-smokers (n = 1,544), 14.8% were smokers (n = 328) and 15.4% former smokers (n = 340), male group were predominant in the smokers and former smokers groups (χ2 = 36.694; p < 0.001); (Figure 1- Panel A).
Figure 1: Cigarette consumption according to sex and age groups in the adult population. Maracaibo, Venezuela. View Figure 1
The average age of non-smokers individuals was 35-years-old (24-48 years old), in contrast with 40-years-old (28-50 years old) for smokers, and 48-years-old (36-56 years old) in former smokers (p < 0.01). The frequency of daily consumption for the smokers was 6 cigarettes/day (2-10) very similar to former smoker with a frequency of 4 cigarettes/day (2-10) p = 0.28. The average time for consumption in smokers was 16 years (6-28 years), significantly superior to the 10 years (4-20 years) observed in former smokers (p < 0.001). All other features concerning the consumption pattern are described in table 1.
Table 1: Smoking pattern characteristics in the adult population. Maracaibo, Venezuela. View Table 1
Cigarette consumption according to age groups
When analyzing cigarette smoking pattern according to age, it was shown that 40-49 and 50-59 years old groups age have the highest percentage of individuals that consumed cigarettes (18.8% [n = 8] and 18.9% [n = 68] respectively). Moreover, individuals in the groups age of 50-59 and ≥ 60 years old showed the highest percentage of former smokers (28.1% [n = 105] and 24.1% [n = 57] respectively, χ2 = 143.19; p < 0.001); figure 1- Panel B. However, it is important to point out that the frequency of smokers is higher among males before 40-years-old while from this age onwards, frequency is equal between genders (Figure 2).
Figure 2: Current cigarette consumption according to gender and age groups in adults. Maracaibo, Venezuela. View Figure 2
Cigarette consumption according to socio demographic variables and psychobiological habits
Among psychobiological variables, alcohol consumption was associated with smoking, showing higher coexistence of both habits in the population 54.0% (n = 177), a higher proportion than the one found in the former smokers (39.4%; n = 134) and non-smokers (26.7%; n = 413); χ2 = 99.147, p < 0.001. In regards to marital status, the highest proportion of non-smokers was observed in singles with 46.3% (n = 710), while married individuals were the largest proportion of former smokers with 52.2% (n = 179), (χ2 = 45.67; p < 0.001). Another variable associated with smoking was the educational status, where individuals who had completed only high school are current smokers with a rate of 35.6% (n = 118) and those who finished a technical/college career had 35.2% (n = 544) for non-smoker and 38.4% (n = 133) for former smokers y (χ2 = 17.07; p < 0.001); table 2. After evaluating cigarette consumption based on occupation, a significant statistical association was observed (χ2 = 132.85; p < 0.001), showing higher percentages for smokers and former smokers individuals who worked in the area of transportation 50.6% (= 40); workmen 45.1% (n = 134) traders 41.7% (n = 68); craft men 36.5% (n = 23); meanwhile, students were the category that showed the lowest percentage with 13.4%. The others categories are show in table 3.
Table 2: Social demographic and clinical characteristics of cigarette smoking patterns in adults. Maracaibo, Venezuela.. View Table 2
Table 3: Working occupation according to cigarette smoking pattern in adults. Maracaibo, Venezuela. View Table 3
Cigarette consumption and clinical metabolic alterations
Regarding the analysis of clinical metabolic alterations, overweight and obesity were more frequent in the former smokers in comparisons with current smokers (χ2 = 132.85; p < 0.001). A similar behave was observed in hypertensive individuals, subjects with metabolic syndrome and impairment fasting glucose. In those subjects with diabetes, the proportions between current and former smokers were similar (current smokers: 16.8% vs former smokers: 15.7%), table 4.
Table 4: Clinical and metabolic alterations according to cigarette smoking pattern in adults. Maracaibo, Venezuela. View Table 4
Cigarette smoking is a major public health problem worldwide [3,22]. The importance of epidemiological surveillance is not only in the partnership it has with several pathologies that impact negatively on the physical and mental well-being of consumers , but also the trained personnel required and the public expense of caring for those affected as a result of complications from this habit. Despite the implementation of policies aimed to decreasing tobacco consumption, the morbidity and mortality rates remain alarming as confirmed by WHO in 2011 . The prevalence of this habit has been extensively studied worldwide, finding wide regional variations. The frequency in our city (14.8%) was similar to that observed in the National Health Interview Survey (NHIS), a study conducted in American individuals over 18 years of age, where it was estimated that 19% of the population consumed cigarettes . However, data published by the Latin American Consortium for the Study of Obesity (LASO)  states that smoking is more prevalent in Latin America in contrast with the US population according to data released by the NHANES 1999-2004 (25.8% vs. 21.0%) .
In studies individually designs for Latin American countries the polls have become a very important element for collecting data relating to smoking. In Brazil, Almeida, et al.  have collected data from nearly 40,000 subjects (≥ 15 mean age) reporting a prevalence of 17.5% for cigarette smoking by 2008. Furthermore, these data collection tools have allowed doing a practical follow up to the population over time, as reported in an Argentinean study  with a sample of 34,372 adults, which reported a smoking prevalence ranging between 29.7% and 27.1% over the time period between 2005 and 2009. Although epidemiological studies concerning about the epidemiological behavior of smoking in our country are limited, WHO estimates its prevalence at 19.4% by 2011 .
When assessing their distribution by gender, our data is similar to the worldwide data [1,29]. Sreeramareddy, et al.  in a study conducted with 15,190 individuals of both genders from Nepal, they found a higher proportion of male smokers compared to females (56.5% CI: 54.1-58.8 vs. 19.6% CI: 18.3-21.0). However, projections indicated that the number of women smokers could increase to approximately 532 million by 2025 . This behavior is observed in our population, specifically in subjects older than 40 years, where the frequency of smoking women equals men. This could be due to several factors that potentially boost consumption of cigarettes in this group of women, including greater access to cigarettes, rising purchasing power, greater autonomy, social determinants such as marital status (increased frequency in divorced women or widows), and changes in the socio-cultural paradigms which traditionally prevented them from smoking and today it is a more socially acceptable habit, a phenomenon particularly noticeable in developing countries .
One of the key points in tobacco control includes the use of measures aimed to decreasing the availability of cigarettes to young people [33,34], because approximately 1 in 5 individuals started cigarette smoking among 18-21 years old  and less than 2% initiates over 27-years-old . In our study, the median age of onset of this habit was 19-years-old (16-25 years) for smokers, similar results to those reported in Malaysia  Kuwait  and Thailand . However, there is a concern about the average age of first use among young consumers because it is diminishing, meaning a decrease in the age when consumption begins. As for the distribution of cigarette smoking by age groups, our results resemble the findings of Li, et al. , who stated that the largest proportion of current consumers individuals are between 45 and 64-years-old.
Meanwhile, in our population it was observed that the education of the individual is strongly associated with smoking, similar to the results of Li, et al. , who reported that the prevalence of cigarette smoking was higher among subjects who attended high school (63.2%), which coincides with our study (35.6%) and lower in those who were graduates in college, university or have postgraduate degrees (44%) similar to the behavior reported in the study by Zhang, et al. , specifically in the male group. The cause of this behavior in individuals with a superior educational status may be due to the intellectual differences that cause disparity in the capacity to know the harmful effects of smoking on health and possibly reduced vulnerability to advertising campaigns .
Marital status is another factor associated with smoking that influences the epidemiological behavior for this habit and previous published studies were agree with our findings , where the highest percentage of smokers was conform by divorced followed by singles individuals, while widows were identified as the group with fewer smokers. Also, in our analysis an association between employment status and smoking were found, the result showed that those employees were the most in the category of smokers, unlike that seen in Britain where it was found that unemployed seeking work were those with an increased incidence of smoking . In assessing by occupations it was reported that 33% of individuals with manual and routine occupations smoked, similar to those that showed our population in which these activities were most prevalent with respect to active consumption of smoking and ex-smoker . With respect to physical activity, no association was found in our population; several studies have reported that physical activity increases the likelihood to smoking cessation in young individuals  however, in adults the results have been controversial .
In regards to the associated metabolic factors, the higher prevalence of obesity and metabolic syndrome in former smoker individuals demonstrated not only the effect in the body weight gain after quit smoking, this is possibly related to a higher caloric intake linked to changes in the central nervous system neurotransmitters . Also it has an effect over metabolic parameters like lipids, insulin resistance and inflammation as it was previously reported and that can be directly influence by tobacco consumption . It is important to be determinate in further research studies in our population if a reversion in the smoking habit exists and how long it takes to be evident.
Finally, due to the high prevalence of chronic diseases previously reported in our city [47,48], including metabolic syndrome with an incidence of 42% in the population, it is important to know the frequency of various modifiable cardio metabolic risk factors, with the purpose of establishing national public health strategies aimed to reducing the incidence of the associated diseases and morbidity and mortality rates. Tobacco consumption represents one of the most important psychobiological habits due to its relationship with different chronic diseases and considering the very few data available in our city, this study shows the main epidemiological characteristics associated, representing one of the biggest studies in the region. However, new analysis is needed in order to determinate the impact of each variable in a multi-variant context as well as research studies that analyses the causality with cardio metabolic diseases.
This study was funded by the Council of Scientific, Humanistic and Technological Development (COUNTS) under No. CC-0437-10-21-09-10 and Fundacite-Zulia under No. FZ-0058-2007.
Conflict of Interest
The authors have no conflicts of interest to declare.
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