International Journal of Pediatric Research (IJPR) is an international peer-reviewed journal committed to promoting the best standards of scientific discoveries and scientific knowledge in the field of pediatrics. IJPR publishes articles on all the aspects related to child health. It acts a best source of information for the pediatricians, child health experts and practitioners.

International Journal of Pediatric Research is a newly launched journal which provides elaborate author benefits along with reliable copy rights policy. We are open to invite experts to join our Editorial board of IJPR. All articles published in the journal will be subjected to a stringent peer review process. It encourages authors to publish their experimental and theoretical results in as much detailed as possible.

Journal Information

Title: International Journal of Pediatric Research

ISSN: 2469-5769

Editor-in-chief: Maria Cristina Azcona San Julian

NLM title abbreviation: Int J Pediatr Res

ICV: 87.93

ISO abbreviation: Int J Pediatr Res

Other titles: IJPR

Category: General Medicine

DOI: 10.23937/2469-5769

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email:

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI


 Open Access DOI:10.23937/2469-5769/1510125

Tetanus in Children Seen at the University Hospital of Professeur Zafisaona Gabriel Mahajanga Madagascar

Ranaivo NAR, Rahariniainasoa A, Ranaivoson H, Rakotohasinoro CA and Andrianarimanana KD

Article Type: Research Article | First Published: 2024/03/20

Tetanus remains a public health problem in developing countries where vaccination coverage is still low, including Madagascar. The aim of this study was to describe the epidemio-clinical aspect of tetanus in children. This was a retrospective descriptive study over a 5-year period, including all children aged between 1 month and 15 years hospitalized for tetanus in the Pediatrics Department of University Hospital Professeur Zafisaona Gabriel (PZaGa) Mahajanga....

 Open Access DOI:10.23937/2469-5769/1510124

Asparaginase-Associated Necrotizing Pancreatitis Successfully Treated with Octreotide: A Case Report and Review of the Literature

Giulia Angela Restivo, MD, Angela Guarina, MD, Barbara Torrente, MD, Sara Genuardi, MD, Piero Farruggia, MD and Paolo D'Angelo, MD

Article Type: Case Report | First Published: 2024/02/15

Pancreatitis is a common adverse reaction to asparaginase and a reason for drug discontinuation in patients with acute lymphoblastic leukemia. Diagnostic criteria include elevated pancreatic enzymes, abdominal symptoms and/or imaging findings suggestive of pancreatitis. There is no specific treatment, but in a few reports, octreotide seems to be an effective drug in reducing acute complications and mortality. Here we describe the case of a child who developed asparaginase-induced necrotizing pan...

 Open Access DOI:10.23937/2469-5769/1510123

Physical Activity Levels of Children and Young People in an Inpatient Setting: A Systematic Review

Kieren James Lock, Colin Hamilton and David Young

Article Type: Review Article | First Published: 2024/02/10

CYP with physical health conditions had significantly lower PA levels than recommendations during inpatient admissions. In contrast, individuals with Anorexia Nervosa (AN) met WHO guidelines for Moderate to Vigorous PA. Fidgeting was observed to be higher in admitted AN patients compared to community, suggesting a potential compensatory mechanism for reduced step count. Notably, hospitalisation itself resulted in a decline in PA levels....

 Open Access DOI:10.23937/2469-5769/1510122

Descriptive Epidemiology of Home-Based Management of Diarrhea in Children Under Five Years: The Case of Northern Ghana

Abdul-Manan Sumani, Benjamin Tommy Bavug, Abdul-Wahid Mahamuda, Husein Abdul-Karim, Abukari Salifu and Al-kabir Mustapha Tahiru

Article Type: Original Article | First Published: 2023/12/28

An institutional based retrospective cross-sectional study design was employed in the study. Data was taken from August 8, 2022 to September 7, 2022 at the child welfare clinic using koboCollect toolbox. Data was extracted from the koboCollect toolbox into Microsoft excel, cleaned and later imported into IBM SPSS statistics version 22 (SPSS) for analysis....

 Open Access DOI:10.23937/2469-5769/1510121

Vertical Transmission of Scrub Typhus in Newborn: A Case Report

Foram A Patel, Bharat Muliya and Dhruti Pandya

Article Type: Case Report | First Published: 2023/12/26

Scrub typhus is an acute febrile mite-born rickettsial infection caused by Orientia tsutsugamushi (formerly called Rickettsia tsutsugamushi ). This infection is very uncommon in neonates. We report a case of 8-day-old newborn presenting with clinical features mimicking severe sepsis but were subsequently diagnosed with primary scrub typhus infection. The timely treatment resulted in dramatic response and complete recovery....

 Open Access DOI:10.23937/2469-5769/1510120

Apnea of Prematurity in the Southern U.S.: The Role of Remote Patient Monitoring Once Discharged to Home

Emily Avery, MPH

Article Type: Review Article | First Published: 2023/10/09

Apnea of prematurity is one of the most common challenges in preterm infants, contributing to the U.S.’s high infant mortality rate. There is a growing need for alignment of remote patient monitoring techniques and at-home care for infants diagnosed with apnea of prematurity, especially in the South where accessibility to health services is lacking....

 Open Access DOI:10.23937/2469-5769/1510119

The Effect of Daytime Sleepiness Experienced by Adolescents Aged 13-18 on Quality of Life

Çiğdem Müge HAYLI, Dilek DEMİR KÖSEM, Neşe ATAMAN BOR, Mehmet ZEKİ AVCI and Mira Rana GÖKDOĞAN

Article Type: Research Article | First Published: 2023/09/21

The data needed for the research were gathered online between 22 October 2022 and 25 February 2023. Adolescents aged 13 to 18-years-old made up the research study. Epworth Sleepiness Scale (ESS) and Quality of Life Scale (SF-36) were used in collecting research data for 420 adolescents between the ages of 13 and 18 years who participated voluntarily and were selected by convenience sampling method from improbable samples, with written consent from their parents, by online survey method. ...

 Open Access DOI:10.23937/2469-5769/1510118

COVID-19 in Children: A Review of Epidemiology, Mode of Transmission, Clinical Presentation, Diagnosis, and Management

Manali Ulhas Desai, MBBS, MPH, PhD

Article Type: Mini Review | First Published: 2023/07/27

COVID-19 disease is a primarily respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmitted by inhaling infected droplets. The primary animal reservoir for the coronavirus virus is the bat. For this review, we searched PubMed on April 30, 2023, with the search strategy: "COVID-19" OR "Coronavirus" AND "Children" AND "Clinical symptoms" AND "Diagnosis" AND "Management." We got 19 search results....

 Open Access DOI:10.23937/2469-5769/1510117

The Frequency and Precipitating Factors for Breakthrough Seizures in Children with Epilepsy

Abdullah Aldosari, Ahmed Alghamdi, Ayidh Alharthi, Abdullah Albuhayri, Suhaib Ghurab, Mohammed Alghamdi and Mufleh Aldosari

Article Type: Original Article | First Published: 2023/06/22

This retrospective study reviewed the charts of children with epilepsy who were followed up in the pediatric neurology clinic of King Fahad Hospital in Al-Baha region, Saudi Arabia, between January 2015 and August 2022. Children between 1 to 14 years of age who had epilepsy, as per the International League against Epilepsy (ILAE) definition, and received anti-seizure medication with a seizure-free period of at least two months before breakthrough seizure episode, were included in the study. ...

 Open Access DOI:10.23937/2469-5769/1510116

Spontaneous Seroma and Septal Hematoma in Children

Valentina Proietti, Juan Dib, Julian Simkim, Juan Carlos Razetti, Federico Herranz, and Carlos Santiago Ruggeri

Article Type: Cases Series | First Published: 2023/06/17

Clinical cases of three pediatric patients who had bilateral spontaneous serous collections and septal hematoma located in the anterior sector of the nasal septum are described. None had a history of trauma or infection, and all were immunocompetent; one was diagnosed with hemophilia type B....

 Open Access DOI:10.23937/2469-5769/1510115

Factors Associated with Neonatal Mortality at Kyeshero Hospital, Goma, North Kivu, DRC

Endanda Zawadi E, Tshivwadi Tshilomb A, Tongota Ntwali J, Mulangu Mutombo A, Imani Musimwa P, Buhoro Baabo G, Mumbere Hangi S, Kyembwa Mwindulwa L, Musafiri Mugisho A, Kabamba Nzaji M and Luboya Numbi Oscar

Article Type: Research Article | First Published: 2023/06/09

The neonatal mortality rate is still a significant public health problem in Sub-Saharan African countries and an indicator of the quality of prenatal and perinatal care. This study aimed to determine the neonatal intra-hospital neonatal mortality rate and the maternal and neonatal risk factors associated with neonatal mortality in Kyeshero Hospital....

 Open Access DOI:10.23937/2469-5769/1510114

Study of Auditory Function Changes in Patients with Down Syndrome

Zoya Ismail Nezha, MD, Youssef Youssef and Yaser Ali

Article Type: Cross-sectional Study | First Published: April 12, 2023

The study involved 30 patients with Down syndrome between 3-18 years-old who had visited ENT clinic in Tishreen University Hospital (TUH) during the period from June 2021 to June 2022. A detailed history was taken, a comprehensive examination of the ear, nose and throat, and auditory tests were taken in each patient case, and the results of these tests were recorded for all patients....

 Open Access DOI:10.23937/2469-5769/1510113

Appearance of Bronchiolitis in Children with Congenital Heart Disease

Randriamanga RLiD , Rakotomalala RLH, Rakotomamonjy HL and Robinson AL

Article Type: Research Article | First Published: March 23, 2023

Bronchiolitis is a viral respiratory infection that is usually mild in infants less than one-year-old but can be serious and fatal in children with underlying heart disease. Our objective was to describe the epidemiological - clinical, therapeutic and evolutionary aspect of the bronchiolitis and heart disease association seen at the Tsaralalàna mother child hospital center. This was a retrospective case-control study over a 5-year period from January 2016 to January 2021; 1 case was matched to ...

 Open Access DOI:10.23937/2469-5769/1510112

Trends and Non-Clinical Predictors of Respiratory Syncytial Virus (RSV) and Influenza Diagnosis in an Urban Pediatric Population

Marina Oktapodas Feiler, PhD, MS, Recai Yucel, PhD, Zhiqing Liu, Mary Caserta, MD, B. Paige Lawrence, PhD, Carter H Pason, Dwight J Hardy, PhD, Kelly Thevenet- Morrison, MS, Ann Dozier, PhD, MS and Todd A Jusko, PhD, MS

Article Type: Original Manuscript | First Published: March 05, 2023

To evaluate the demographic, maternal, and community-level predictors of pediatric respiratory syncytial virus (RSV) and influenza diagnosis among an urban population of children residing in Rochester, NY. A test-negative case-control design was used to investigate various non-clinical determinants of RSV and influenza diagnosis among 1,808 children aged 0-14 years who presented to the University of Rochester Medical Center (URMC) or an affiliated health clinic in Rochester, NY between 2012-2019...

 Open Access DOI:10.23937/2469-5769/1510111

Study of Clinicopathological Profile and Outcome of Patients with Septic Shock in PICU of Tertiary Care Hospital

Bansude A, Sanjay Natu, Kulkarni K and Deshpande

Article Type: Original Article | First Published: February 25, 2023

Sepsis is a leading cause of morbidity, mortality and health care utilization for children worldwide. Mortality for children with sepsis ranges from 4% to as high as 50%, depending on the severity of illness, risk factors and geographic location. The majority of the children who died from sepsis suffer from refractory shock and/or multiple organ dysfunction syndromes, with many deaths occurring within an initial 48 to 72 hours of treatment....

 Open Access DOI:10.23937/2469-5769/1510110

Effect of Music on Infant Stress as Measured by Cortisol Levels and Premature Infant Pain Profile: A Systematic Review with Meta-analysis

Marissa Elizabeth L Lim, MD, MS and Francisco Jr E Anacleto

Article Type: Review Article | First Published: February 24, 2023

Marissa Elizabeth L Lim, MD, MS, Department of Physiology, College of Medicine, University of the Philippines, Manila, Philippines, Tel: 09178651389...

 Open Access DOI:10.23937/2469-5769/1510109

First Step in Developing a Pediatric Sedation Team: Evaluation of Procedural Sedations Performed for Imaging and Procedures in an Academic Children’s Hospital

Rebecca Morgis, BS, Radhika Sood and Angel Lorrine Schuster, MD

Article Type: Original Article | First Published: February 15, 2023

Procedural sedation for children is often necessary because it helps limit pain and anxiety and increases the chance of a successful procedure or diagnostic image. A pediatric sedation team (PST), made of an interdisciplinary team can help ensure safe and timely sedations. Our Children’s Hospital (CH) does not have a PST and our goal is to establish one. For this study, our objective was to evaluate sedations performed throughout the CH as part of a longitudinal project to create a PST....

 Open Access DOI:10.23937/2469-5769/1510108

Risk Factor of Cerebral Vasculopathy in Children with Sickle Cell Disease in Madagascar

Andrianarivony RT, Randriamanga RL, Tsifiregna RL, Ravelomanana L and Razafiarisoa N

Article Type: Research Article | First Published: February 05, 2023

Sickle cell disease is a genetic disease that is common in Madagascar with serious complications. The cerebral vasculopathies are among the most dreadful complications by its morbid mortalities. In Madagascar, these cerebral vasculopathies in children with sickle cell disease are not sufficiently studied, and the risk factors are still unknown, hence the goal of our study....

 Open Access DOI:10.23937/2469-5769/1510107

Utilization of Integrated Community Case Management of Common Childhood Illness and Associated Factors among Mothers/Caregivers in Wonsho District, Sidaama Region: Ethiopia

Ribato Rikiba and Asegid Regas

Article Type: Research Article | First Published: February 03, 2023

Integrated Community Case Management (ICCM) is a community care strategy which seeks to extend case management of childhood illness beyond health facilities to the community level so that more children have access to lifesaving treatments. It is one of the high impact programs and interventions for child survival and provided by community health workers (CHWs) at the lowest level health units or in the community during home visits that can increase coverage of specific treatments and lead to sub...

 Open Access DOI:10.23937/2469-5769/1510106

Strategies for Improving Viral Suppression among Children Living with HIV Considered to be Failing First-Line Antiretroviral Therapy in Akwa Ibom, Nigeria: A before - after Study

Uduak Akpan, Kufre-Abasi Ukpong, Esther Nwanja, Otoyo Toyo, Christa Walker, Iheanyichukwu Elechi, Pius Nwaokoro, Olusola Sanwo, Titilope Badru, Augustine Idemudia, Satish Pandey, Hadiza Khamufo and Moses Bateganya

Article Type: Original Article | First Published: January 22, 2023

The study report the results of a quality improvement (QI) program implemented to improve viral suppression (VS) in a cohort of children living with HIV who had viremia (viral load [VL] ≥ 1,000 copies/mL) despite being on effective antiretroviral therapy (ART). The Meeting Targets and Maintaining Epidemic Control (EPIC) project’s quality assurance/ quality improvement team monitors quality across HIV/ AIDS thematic areas. Epic collaborated with the state pediatric task force supporting pedia...

 Open Access DOI:10.23937/2469-5769/1510105

Atypical Respiratory Distress Syndrome in Children Affected with COVID-19

Samia Tilouche, MD, Sameh Ghorbel, MD, Emna Sfar, MD, Najoua Kahloul, MD, Mohamed Mahjoub, MD, Najla Soyah, MD, Naila Hannachi, MD, Jihene Bouguila and Lamia Boughamoura, MD

Article Type: Case Report | First Published: January 20, 2023

Early research and data on Coronavirus disease 2019 (COVID-19) have proven that pediatric clinical forms are not serious in many cases. However, the disease can progress to acute respiratory distress syndrome (ARDS) and multi-organ dysfunction and lead to death. In the present paper, we report one of the first Tunisian critical pediatric cases, a 6-year-old girl with an atypical ARDS secondary to severe acute respiratory syndrome coronavirus 2 (SARS- CoV2) that was supported by non invasive ven...

 Open Access DOI:10.23937/2469-5769/1510104

Ventricular Conduction Disorders in Pediatrics: Bundle Branch Blocks- Update

Garcia Cuesta A, Villanueva García A, Uberos Fernández J and Blanca Jover E

Article Type: Review Article | First Published: January 16, 2023

The interruption of the cardiac conduction system that occurs in the ventricles, anatomically after the electrical impulse leaves the atrioventricular node, generates bundle branch block. With a particular electrocardiographic morphology, specific measurable and revealing of its topography, it may be related to underlying cardiac pathology, although it also exists in hearts without pathology. Compared to adults, there are more frequent patterns of presentation in the paediatric age, such as righ...

 Open Access DOI:10.23937/2469-5769/1510103

Hip Dysplasia in Congenital Zika Syndrome: A 5 Year Follow- Up

Andréa F Magalhães iD , Carla ACT Caldas iD and Vinícius I de Lucca

Article Type: Original Research | First Published: January 08, 2023

Children with Congenital Zika Syndrome (CZS) usually have severe neurological impairment with extrapyramidal involvement mainly spastic quadriplegia, so we believe they would have the same spasticity-related abnormalities, such as high prevalence of hip subluxation, as children with other aetiologies of cerebral palsy (CP). The aim of this study was to investigate hip status and describe the radiographic measures, Reimer’s migration percentage (MP) and acetabular index (AI) in infants diagnose...

 Open Access DOI:10.23937/2469-5769/1510102

Meeting the Needs of Children in Pediatric Hospitals: An Analysis of Professional Roles

Emily P Finley and Holly H Hoffman, PhD

Article Type: Original Research | First Published: December 10, 2022

Every year millions of children experience being a patient in a hospital setting. When hospitalization is required, many challenges related to coping skills and development face children and families. Examples include being taken out of their typical setting, managing new information, and limited social interactions. This study gathered insights from 203 healthcare professionals (child life specialists, social workers, and counsellors) who work with pediatric patients....

 Open Access DOI:10.23937/2469-5769/1510101

Knowledge, Attitudes and Practices of Mothers on Neonatal Danger Signs

Ramamonjinirina TP, Tsifiregna RL, Rabemananjara A, Rakotondravelo SM and Rabesandratana N

Article Type: Research Article | First Published: October 13, 2022

Neonatal mortality is still a public health problem. The objective of our study was to evaluate the knowledge, attitude and practices of mothers in the Fianarantsoa Level 2 Basic Health-care Centers, face to neonatal danger signs. This was a prospective cross-sectional study of pregnant women of the second gestational age and above (parity ≥ 1), who came for prenatal consultation in public health centers, on their knowledge, attitudes, and practices in front of neonatal danger signs. The surve...

 Open Access DOI:10.23937/2469-5769/1510100

Tension Pneumothorax in 5-Months Old Infant - An Atypical Presentation of CPAM Type I

Dorotea Keretic, Andro Gliha, Stjepan Visnjic, Andrija Car, Ivan Petracic, Josip Pejic, Ana Tripalo Batos, Monika Ulamec, Leon Romcevic and Antonija Gojenovic

Article Type: Case report | First Published: June 24, 2022

Congenital pulmonary airway malformation or CPAM is a rare anomaly which affects specifically one and usually lower lung lobe. In most cases it is detected during prenatal life with foetal ultrasound, but it`s not uncommon to find CPAM in background of frequent respiratory infections in childhood, rarely even in adulthood. In this paper, our aim is to present an atypical presentation of CPAM type I which we had difficulties to diagnose....

 Open Access DOI:10.23937/2469-5769/1510099

High Prevalence of Neonatal Respiratory Distress and its Possible Etiologies in NICU in Syria

Fareeda Wasfy Bijow, MD, Oday Jouni, MD and Adnan Dayoub, MD

Article Type: Original Article | First Published: July 18, 2022

Neonatal Respiratory Distress (NRD) is one of the most causes of hospitalization in Neonatal Intensive Care Units (NICU) worldwide in both preterm and full-term neonates. Its prevalence and etiologies vary according to several geographic, ethnic and service factors. We aimed to determine Prevalence and etiologies of NRD in NICU in Tishreen University Hospital in Lattakia, Syria....

 Open Access DOI:10.23937/2469-5769/1510098

Etiological Classification of Short Stature in Children over 5 Years Old

Suhad Abdullah, Ahmed Chreitah and Youssef Zreik

Article Type: Original Article | First Published: June 30, 2022

Short stature is a common problem in childhood, which may be a normal variant of growth or the result of pathologic conditions. Determination of the etiological factors would lead to more appropriate assessment and clinical approach for patients. The aim of this study is to describe the etiologies of short stature among children....

 Open Access DOI:10.23937/2469-5769/1510097

The Atopic Diseases in Children Having Eosinophilic Gastroenteritis

Reman Ali Ali, Ali Mohammed, and Maamoun Hakim

Article Type: Original Article | First Published: May 30, 2022

Eosinophilic gastroenteritis is a chronic antigen mediated inflammatory disease that may occur in any part of the intestine, with a significant increase in the incidence in the last years. It might correlate to the increasing in atopic diseases....

 Open Access DOI:10.23937/2469-5769/1510096

Determinants of Community-Acquired Pneumonia among under-Five Children in Tehulederie District, Northeast Ethiopia

Getahun Ali, Alemayehu Shimeka and Ayalew Kassaw

Article Type: Research Article | First Published: May 30, 2022

Pneumonia is the leading cause of mortality and morbidity in under-five children which accounting two million under-five deaths each year globally. Half of these deaths occur in Sub-Saharan Africa. Regardless of this fact, efforts to identify determinants of pneumonia have been limited in the study area....

 Open Access DOI:10.23937/2469-5769/1510095

Variants in TBCK cause Global Developmental Delay, Dysmorphism, Hypotonia

Maha Alotaibi and Shaza M Aloulou

Article Type: Case Series | First Published: April 25, 2022

A protein kinase domain, a Rhodanase-like domain, and the Tre-2/Bub2/Cdc16 (TBC) domain are all encoded by the TBCK gene. By modulating the mammalian target of rapamycin (mTOR) signaling pathway, the encoded protein is hypothesized to play a role in actin organization, cell growth, and cell proliferation. Has a role in the organization of the actin cytoskeleton. This protein may also play a role in the transcriptional control of mTOR complex components. And it’s found practically everywhere, i...

 Open Access DOI:10.23937/2469-5769/1510094

Paracetamol Poisoning: Need to Remember Nephrotoxicity

Inês Rosinha, Marta Machado, Carolina Cordinhã, Carmen Do Carmo and Clara Gomes

Article Type: Case Series | First Published: April 11, 2022

Paracetamol overdose is an important cause of drug toxicity and pediatric overdose emergencies remain a significant global issue. Paracetamol is a known toxin to several tissues, but extrahepatic manifestations are not so well established as hepatotoxicity. Acute kidney injury occurs in up to 2% of paracetamol overdoses, generally coexisting with hepatotoxicity. A 14-year-old female adolescent presented to the emergency department 24 hours after a purposeful overdose of 22.5 grams of paracetamol...

 Open Access DOI:10.23937/2469-5769/1510093

Pediatric Abusive Head Trauma: A Case Series in a Tertiary Hospital

Andreia Marinhas, Ana Isabel Martins, Anabela Fazendeiro, Patrícia Lourenço, Filomena Freitas, Marta Machado and Beatriz Maia Vale

Article Type: Case Series | First Published: March 30, 2022

Characterise cases of Abusive Head Trauma (AHT) over an 8-year period in a tertiary hospital in Portugal, including the main demographic and clinical characteristics, as well as long-term follow-up and sequelae. Retrospective review of all cases of AHT admitted between 1st of January 2013 and 31st of December 2020 in a Portuguese pediatric tertiary hospital. We characterize all cases descriptively, about demographic, clinical and social characteristics. Between 2013 and 2020, 7 cases of abusive ...

 Open Access DOI:10.23937/2469-5769/1510092

Transition from Pediatric to Adult Care of Pediatric Patients with Chronic Disease: Experiences and Perspectives of Pediatricians and Internists at a Private Tertiary Hospital in the Philippines

Maria Anna F Perez, MD, Rosa Maria Nancho, MD, FPPS, FPSAMS, FiFePAG and Rhea Salonga-Quimpo, MD, FPPS, FCNSP, FPNA

Article Type: Original Article | First Published: March 30, 2022

The improving survival rates and life expectancy of patients with pediatric-onset chronic diseases led to a rise in the number of individuals requiring transition to adult care. A successful Health Care Transition (HCT) is vital in ensuring therapy adherence, continuity of care, and positive health outcomes. Both pediatricians and internists are key stakeholders in the transition process and have equally valuable input in improving HCT policies and programs. Pediatricians and internists in activ...

 Open Access DOI:10.23937/2469-5769/1510091

Clinical Manifestations in the Pediatric Patient with Post- COVID-19 Syndrome: A New Challenge for the Preservation of Functional Capacity

Ana María Zuleta-Monsalve, Carol Juliana Parra-Navarro, Kelly Marcela Ceron- Benavides, Yenny Alexandra Moreno-Giraldo and Maria Paz Bolaño-Romero

Article Type: Editorial | First Published: March 16, 2022

The COVID-19 pandemic has raised numerous questions about the prognosis of those affected by this disease, especially in children. Based on cases described in the literature, Nakra, et al. investigated a severe condition about which little is currently known: Multisystemic inflammatory syndrome in children associated with COVID-19. The authors hypothesized pathogenic mechanisms, and reported which were the most frequent clinical manifestations, taking into account that this syndrome can present ...

 Open Access DOI:10.23937/2469-5769/1510090

A Text Message Intervention for Weight Management in Childhood Obesity at the Pediatric Office

Ala Elayyan, MD, MPH, FAAP, CNSC, Dipl. of ABOM

Article Type: Research Article | First Published: March 09, 2022

Childhood overweight and obesity is a major public health problem affecting one-third of children and adolescents in the United States, it has been linked to significant health risks and comorbid conditions in children and adults as it has direct associations with chronic health problems in children and adults not limited to diabetes, dyslipidemia, heart disease, non-alcoholic fatty liver disease, and many others. Childhood obesity is usually diagnosed and managed at the primary care office but ...

 Open Access DOI:10.23937/2469-5769/1510089

Effectiveness of Polyethylene Glycol 3350 versus Lactulose in Management of Functional Constipation in Children

Hanin Ahmed Mansour, MD, Ali Ibrahim and Ali Mohammad

Article Type: Research Article | First Published: March 09, 2022

Constipation is one of the common problems in childhood. Recently, Polyethylene Glycol (PEG 3350) has been suggested as a good alternative laxative to Lactulose as a treatment option in pediatric constipation. The current study aimed to compare the efficacy of two laxatives (PEG 3350 and Lactulose) in the management of functional constipation and evaluate the side effects. In an open-label clinical trial, 1-13 year-old children with functional constipation according to ROME IV criteria and the p...

 Open Access DOI:10.23937/2469-5769/1510088

Perinatal Risk Factors and Early Onset of Neonatal Sepsis

Fedaa Noah Noah, MD, Leen Jamel Doya, MD and Oday Jouni

Article Type: Observational Descriptive Study | First Published: February 21, 2022

Neonatal sepsis contributes significantly to neonatal morbidity and mortality and is an ongoing major global public health challenge particularly in developing countries. The study aims to determine the prevalence of early neonatal infections and risk factors associated with neonatal intensive care. In a cross-sectional study that included all newborns admitted to the neonatal intensive care of Tishreen University Hospital from October 2019 for one year and who fulfilled clinical and laboratory ...

 Open Access DOI:10.23937/2469-5769/1510087

Newborn Resuscitation Scale Up and Retention Program Associated with Improved Neonatal Outcomes in Western Nepal

Naresh Pratap KC, Ranjan Dhungana, Emily Gamboa, Siena F Davis, Michael K Visick and Robert B Clark, MD, MPH

Article Type: Original Article | First Published: February 07, 2022

The adoption of Helping Babies Breathe (HBB) tool has improved the outcomes of neonatal resuscitation following intrapartum events. Perinatal asphyxia however remains a leading cause of neonatal morbidity and mortality in Nepal. HBB training has proven effective, but a major challenge is maintaining resuscitation skills over time. Safa Sanaulo Nepal (SSN) designed an evidence-based strategy for scaling up training and sustaining long-term retention. This paper describes the implementation of SSN...

 Open Access DOI:10.23937/2469-5769/1510086

Decision Making Surrounding Mode of Initial Enteral Feeding in Critically Ill Pediatric Patients

Arianne M Maya, BS, Kathleen R Ehresmann, MD, Moiz M Mustafa, MD, Janice A Taylor, MD, MEd, Shawn D Larson, MD, Saleem Islam, MD, MPH and Robin T Petroze, MD, MPH

Article Type: Original Article | First Published: January 21, 2022

Wide practice variation and weak guidelines exist when considering enteral feeding options and the decision to proceed with gastric or postpyloric enteral feeding in critically ill infants and children. The purpose of this pilot study is to explore provider decision making in early feeding of critically ill pediatric patients, review the indications for choice of enteral feeding access, and qualitatively explore the role of institutional culture in medical decision making. In-person structured i...

 Open Access DOI:10.23937/2469-5769/1510085

Shiga Toxin Producing Escherichia coli Infections and Associated Haemolytic Uraemic Syndrome in New Zealand Children: Twenty Three Years of Epidemiology and Clinical Observations

William Wong, MB, ChB, FRACP

Article Type: Original Article | First Published: January 10, 2022

The epidemiology of childhood haemolytic uraemic syndrome in New Zealand was on active surveillance from January 1, 1998 to December 31, 2020. The aim of this study is to describe the demographic, epidemiological and some clinical features of childhood Shiga toxin producing E. coli infections (STEC) and its association with diarrhoea associated haemolytic uremic syndrome (D+HUS) over past 23 years. The New Zealand Paediatric Surveillance Unit (NZPSU) sent out a monthly report card to all practis...

 Open Access DOI:10.23937/2469-5769/1510084

Dose-Delivery Time Interval of Morphine in Labour and its Impact on the Likelihood of Adverse Neonatal Outcomes

Ranatunga M and Doctor TN

Article Type: Original Article | First Published: December 26, 2021

To find the effect that time between dosage of morphine and delivery of the baby has on the incidence of need for neonatal resuscitation. Retrospective analysis of 659 births at The Northern Hospital, Epping, Victoria, featuring use of morphine in labour. Time between morphine dose and delivery of baby was recorded for each birth, known as the dose-delivery interval (DDI). Four equally distributed categories were created based on quartiles of DDI. Various neonatal outcomes were compared between ...

 Open Access DOI:10.23937/2469-5769/1510083

Lead Poisoning in Pediatric Groups: A Global Burden of Disease

AB Adeyiga

Article Type: Review Article | First Published: December 17, 2021

Lead poisoning is a major public health issues that affect pediatric age group with different multi-organ damage. In children for instance, it has been discovered that there is no small level or appreciable quantity of lead exposure that is safe for children because of developmental growth and cognitive development at this very crucial stage of life. Children are at very high risk because of their handto- mouth explorative behaviors at this developmental age thereby leading to unintentional inge...

 Open Access DOI:10.23937/2469-5769/1510082

Complementary and Alternative Medicine among Inpatient Pediatric Under One Year of Age in Baghdad City-Iraq

Suadad J Al-Daboony, MBCHB-FICMS(CM)

Article Type: Cross-Sectional Study | First Published: December 16, 2021

Complementary & alternative medicine popular in Iraq, its use from many age group but shortage of data is available about uses of traditional medicine in pediatric. The aim of this study to measure the prevalence of complementary and alternative medicine CAM (one type of CAM called saqua) use in acutely sick children (complaining from gastro intestinal symptom) and factors associated with it. This is a cross-sectional study, hospital-based study in a tertiary center of Baghdad City- Iraq from t...

 Open Access DOI:10.23937/2469-5769/1510080

Essential Newborn Care in the Municipality of Kara (North Togo) in 2019

Segbedji KAR, Tchagbele O-B, Talboussouma SM, Agrigna H, Kombieni K, Atakouma YD and Azoumah KD

Article Type: Original Article | First Published: October 08, 2021

Every newborn at birth needs an adequate essential care provided by qualified personnel in order to reduce neonatal morbidity and mortality. The aim of this study was to evaluate the practice of essential newborn care (ENC) in two tertiary hospitals in the City of Kara (North Togo). It was a prospective and descriptive study about ENC, carried out from March 1st to May 30th of 2019. The study was focused on newborns after their immediate vaginal delivery, their mothers and the hospital personnel...

 Open Access DOI:10.23937/2469-5769/1510079

Assessment of Magnitude and Associated Factors of Immunization Drop Out Rate for Children Aged 12-23 Months In Abobo District South West Ethiopia

Ayalew Kassaw, BSC, MPH IN RH, Abebe Gebere Mariam, BSC, MPH, PHD, Alemi Kebede, BSC, MPH IN RH, and Fassikaw Kebede, BSC, MPH (Epidemiology)

Article Type: Research Article | First Published: September 20, 2021

Vaccination is the epicenters of preventive care for good children health outcomes in each nation. Nevertheless, numbers of factors have been hindering the attainment of targets to provide complete vaccination in different nations. The aim of this study is to assessed predictors of immunizations in 12-23 months aged children in Abobo District, Gambela regions south west Ethiopia. A community based cross-sectional study was employed in 436 pairs of mothers to children aged 12-23 months from 12 ma...

 Open Access DOI:10.23937/2469-5769/1510078

The Use of Hypnosis for the Treatment of Nocturnal Enuresis: Myth or Reality?

Anna Maria Della Grotta, MD and Alessandro Boscarelli, MD

Article Type: Commentary | First Published: August 30, 2021

Nocturnal enuresis is a common condition which may be cause of considerable psychological distress especially in children. Despite poor evidence across the literature, hypnosis could have an important role as first-line treatment option for primary monosymptomatic nocturnal enuresis. Nocturnal enuresis, also called bed-wetting or night-time incontinence, is a common condition which may be cause of considerable psychological distress especially in children. Nocturnal enuresis refers to the involu...

 Open Access DOI:10.23937/2469-5769/1510076

Serum 25-Hydroxyvitamin D Levels of Apparently Healthy Nigerian Children Aged 1-24 Months

Akeredolu FD, Akuse RM, Mado SM and Yusuf R

Article Type: Original Article | First Published: July 23, 2021

The role of vitamin D in promoting health and contributing to disease is an emerging area of research interest that has important health care and public health implications. As the health relevance of vitamin D outside bone health is now being explored globally, scanty data is available about the vitamin D status of healthy Nigerian children. Because Infants and young children have a relatively low supply of foods rich in vitamin D and may also have inadequate exposure to sunlight, they are at r...

 Open Access DOI:10.23937/2469-5769/1510075

Lactate Dehydrogenase Level as an Early Predictor of Transient Tachypnea of the Newborn Duration and Complications

Mada Osefori, MD, Leen Jamel Doya, MD, Bana Nezha, MD and Adnan Dayoub

Article Type: Cross Sectional Study | First Published: June 11, 2021

Transient tachypnea of the newborn (TTNB) is a common cause of respiratory distress in the postnatal period. It is rarely associated with serious complications that need intensive care. Prediction of the complications during the first hours of hospitalization is very difficult, so the purpose of the current study is to investigate the relationship between lactate dehydrogenase (LDH) level in blood and the course of Transient tachypnea of the newborn (the duration of hospitalization, and the inci...

 Open Access DOI:10.23937/2469-5769/1510074

Bacteremia in Pediatric Gastroenterology Patients with Central Venous Catheters Presenting to the Emergency Department

Courtney E Brennan, MD, Choo Phei Wee, MS, Jared Schiff, MD and Alan L Nager, MD, MHA

Article Type: Original Research | First Published: April 21, 2021

Medical records were retrospectively reviewed for gastroenterology patients presenting to a single, Pediatric Emergency Department with fever and a CVC from April 1, 2014 to December 31, 2016. The primary outcome measure is a positive blood culture. Additional variables studied include age, sex, history of prematurity, primary GI diagnosis, type of CVC and when it was inserted, the presence or absence of an enteral feeding tube, the use of total parenteral nutrition (TPN), weight, ED presenting ...

 Open Access DOI:10.23937/2469-5769/1510073

Neonatal Hyperbilirubinemia in Low-Income African Countries

Adam C Gamber, Ethan M Toth, Hendrik J Vreman and Tina M Slusher

Article Type: Review Article | First Published: February 19, 2021

Neonatal hyperbilirubinemia, also known as jaundice, is a significant cause of neonate death and disability in low- and middle-income countries (LMICs). Lack of adequate healthcare facilities, unreliable diagnostic- and treatment equipment, limited parental knowledge, and inconsistent- or absent treatment protocols all contribute to exceptionally high rates of morbidity and mortality especially in Sub-Saharan Africa. This review summarizes the etiology and treatment of neonatal hyperbilirubinemi...

 Open Access DOI:10.23937/2469-5769/1510072

The Usefulness of High Sensitivity C-Reactive Protein (hs- CRP) to Differentiate between Severe and Non-Severe Dengue in Children

Aaradhana, Bineeta Kashyap, Krishna Singhla and Rahul Sharma

Article Type: Original Research | First Published: December 31, 2020

High sensitivity CRP (Hs-CRP) has not been studied in children with dengue so far. We conducted this descriptive cross-sectional study to compare hs-CRP levels between a group of 31 children under 12 year of age with dengue (positive NS1 antigen and/IgM ELISA for dengue) and healthy comparison group and between severe and non-severe dengue cases. Hs-CRP levels were assessed in sera of hospitalized dengue cases and healthy controls. Median (IQR) hs-CRP levels were 46.59 (34.8, 67.0) mg/L and 0.53...

 Open Access DOI:10.23937/2469-5769/1510071

Novel Technique of Wire-Guided Retrograde Esophageal Dilatation in Infants Using Feeding Tubes: The “DRIFT” Technique

Ravi Patcharu, MS, MCh, Karunesh Chand, MS, MCh and Badal Parikh, MD

Article Type: Research Article | First Published: November 05, 2020

Esophageal dilatation is the modality of choice for managing anastomotic stricture after primary repair of esophageal atresia (EA). Balloon dilatation over guide wire is the preferred technique with minimal chances of mucosal erosion. In some cases of tight strictures, safe antegrade dilatation becomes impossible if the guidewire cannot be negotiated across the stricture. In such situations, retrograde dilatation is a safer alternative to avoid another thoracotomy for stricture resection and ana...

 Open Access DOI:10.23937/2469-5769/1510070

Our Experience Treatment Inhalation Injury in Children in Uzbekistan

Babur M Shakirov, PhD and Noila Ashurova, MD

Article Type: Research Article | First Published: October 23, 2020

Thermal inhalation injury is one of the factors aggravating the course of burn disease and resulting in patient’s death. According to literary data, damage to respiratory tract occurs approximately in 30% of cases with severe burn injury. Thermal inhalation injury severity can be determined not so much by airway burns but by toxic inhalation damage to the lungs and whole body with high toxic gaseous and vaporized chemical components of smoke. During a 3 year period 28 children with deep burns ...

 Open Access DOI:10.23937/2469-5769/1510069

Highly Sensitive Cardiac Troponin T as a Biomarker of Myocardial Injury in Acyanotic Congenital Heart Disease

Rishika Das, RN Mandal, Anurag Agarwal, Sumod Kurian and Bhawna Mahajan

Article Type: Original Article | First Published: October 14, 2020

An observational cross sectional study was conducted at a tertiary care center over a period of one year (April 2017 to March 2018). Stable children with ACHD aged between 6 months to 5 years were selected as cases and age matched children without ACHD as controls. Echocardiography was done in all the patients with clinical findings of ACHD. A total of 83 children (55 cases and 28 controls) were enrolled. The severity of the ACHD was determined by the defect size and the pressure gradient across...

 Open Access DOI:10.23937/2469-5769/1510068

Results in Neurodevelopment after Open Cardiac Surgery in Pediatric Patients

Adriana Nieto-Sanjuanero, Arturo Alejandro García-Ramírez, Ramón Gerardo Sánchez-Cortés, Joshua Rodrigo De la O-Vega, Arturo Gerardo Garza-Alatorre and Manuel Enrique De la O-Cavazos

Article Type: Original Article | First Published: October 03, 2020

Heart diseases are considered among the most frequent congenital malformations; they have a great impact on pediatric morbidity and mortality. Children with congenital heart disease present motor and neurocognitive deficits, as well as specific functions such as attention and executive functions can be affected. It is an observational, analytical, retrospective, and cohort study, in which 10 postoperative cardiac surgery patients with the use of an extracorporeal pump were recruited regardless o...

 Open Access DOI:10.23937/2469-5769/1510067

Cronobacter sakazakii in Infant Food Contamination and Its Survival Strategies in Hostile Conditions

Gedif Meseret Abebe

Article Type: Review Article | First Published: August 08, 2020

Cronobacter sakazakii is an opportunistic foodborne pathogen that causes diseases like meningitis, necrotizing enterocolitis, and bacteremia in immunocompromised, low weight individuals, neonates, infants, and elders. Cronobacter sakazakii has the ability to persist in extremely dried foods such as powdered infant formula (PIF). Infant food contamination by this bacterium is attributed to biofilm which are microbial communities attached to biotic or abiotic surfaces using a self-produced matrix ...

 Open Access DOI:10.23937/2469-5769/1510066

Hypoglycemia in Exclusively Breastfed High-Risk Neonates - A Hospital-Based Study

Parth Patel, Palash R Gogoi, Santanu Deb, Prasenjit Paul, Sabrina Yesmin, Lima Sangla Jamir and Pramod Paharia

Article Type: Original Research | First Published: July 16, 2020

Hypoglycemia is one of the commonest metabolic problems in contemporary neonatal medicine. In the majority of healthy neonates, the frequently observed low blood glucose concentrations are not related to any significant problem and merely reflect normal processes of metabolic adaptation to extrauterine life. However, when low blood glucose levels are prolonged or recurrent, they may result in acute systemic effects and may result in neurologic sequelae....

 Open Access DOI:10.23937/2469-5769/1510065

Cutis Laxa Syndrome

Chaima Rherib, Fatima Jabourik and Abdelali Bentahila

Article Type: Image Article | First Published: July 15, 2020

18-months-old girl, the child of related parents, with no particular pathological history, presented with respiratory disorders associated with the fever and cough. On The clinical examination, the child was febrile and had respiratory distress. The respiratory rate was 60/ min, heart rate 100/min, and blood pressure 100/70 mmHg, The weight and height were 10 kg (under 2DS) and 70 cm (normal for that age) respectively the facies was particularly suggestive of cutis laxa: An early senile appearan...

 Open Access DOI:10.23937/2469-5769/1510064

Prevalence of Femoral Head Ostenecrosis in Patients with Falciform Anemia: A Bibliographic Review in Pediatrics

Valeria Botelho, Ingridy Caroline Ferreira Silva, Paula Braga Daltro, Indiry Caroline Ferreira Silva, Rodrigo Jorge de Souza da Fonseca, Jane Mary de Medeiros Guimarães, Gildásio Daltro

Article Type: Review Article | First Published: June 25, 2020

An electronic search for studies developed in the last 20 years in the main databases was carried out: PUBMED, SCIELO, MEDLINE and BIREME using the descriptors: Femoral head osteonecrosis, sickle cell anemia, prevalence associated with Boolean operators: or and and. Studies published in English, pediatric age range between 0 and 18 years and studies available for access, were adopted as limits. At the end, 28 scientific articles were found. After reading the title and summary, only one study fit...

 Open Access DOI:10.23937/2469-5769/1510063

Socio-Demographic Factors Associated with Late Presentation and Outcome of Febrile Children Admitted in a Tertiary Facility in North-Western Nigeria: A Comparative Study

Khadijat Omeneke Isezuo, Ben Oloche Onankpa, Asmau Adamu, Fatima Bello Jiya, Maryam Amodu-Sanni, Bilkisu Ilah Garba, Olubusola Busayo Okwuolise and Edzu Usman Yunusa

Article Type: Original Article | First Published: June 11, 2020

Delay in seeking appropriate health care by caregivers is an important modifiable factor which contributes to childhood morbidity and mortality in developing countries. This study was carried out to assess the socio-demographic factors associated with late hospital presentation and outcome of acute febrile illnesses among children aged < 15 years in an emergency unit. Hospital based study in the Emergency Paediatric Unit of Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto....

 Open Access DOI:10.23937/2469-5769/1510062

The ACE2 Receptor in SARS-CoV-2 and HCoV-NL63: Potential Relationship with Kawasaki Disease in Children?

Ruth E Propper, PhD

Article Type: Letter to the Editor | First Published: May 29, 2020

Coronavirus disease 2019 (COVID-19), the illness caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is currently causing a global pandemic. Despite its easy transmissibility and oftentimes severe course in adults, children have been predominantly spared the worst of the disease, tending to suffer only mild illness. However, recently across multiple countries, there have been hundreds of anecdotal reports of Kawasaki, or Kawasaki-like disease, in children, potentially linked ...

 Open Access DOI:10.23937/2469-5769/1510061

Giant Thoracic Ganglioneuroma with Mass Effect: A Case Report

Adil ZEGMOUT, Hanane CHARAF, Abdelhalim BOUCAID, Youness AMCHICH, Hicham SOUHI, Hanane EL OUAZZANI, Ismail Abderrahmane RHORFI and Ahmed ABID

Article Type: Case Report | First Published: May 08, 2020

Thoracic ganglioneuromas are exceedingly rare. They arise from neural crest cells. These tumors are mostly asymptomatic, but massive tumors can present symptoms related to locoregional compression like dyspnea or scoliosis. We report a case of thoracic paravertebral giant ganglioneuroma in a 12-year-old child presenting as a large intrathoracic mass in the posterior mediastinum with intimate contact with the dorsal spine. That masse causes skeletal deformity and scoliosis. Scoliosis secondary to...

 Open Access DOI:10.23937/2469-5769/1510060

Impact of Low Grade Periventricular-Intraventricular Hemorrhage on Neurodevelopmental Outcome of Preterm Infants

Atef Alshafei, MRCPCH. MSc

Article Type: Review article | First Published: April 09, 2020

Improvement of neonatal intensive care in the modern era has greatly changed the demographic image with evolving new generation of extreme preterm survivors. And indeed, evolving new co-morbidities that influence the short and long-term outcomes of these infants. Periventricular-Intraventricular hemorrhage (PVH-IVH) is a significant health problem affecting the brain structures in a critical stage of development in preterm infants. Although the incidence has declined since the 80's of the last c...

 Open Access DOI:10.23937/2469-5769/1510059

Association between Sociodemographic Factors and Sleeping Patterns from Infancy to Four Years of Life in Saudi Community

Gigi Sam, Sarah Zinaf, Maha Hamoud and Noora Inad

Article Type: Original Article | First Published: February 13, 2020

Sleep is a prime factor of healthy development and has been associated with emotional, behavioural, and cognitive development. This study investigates sleep parameters and associated sociodemographic characteristics in a population-based online method in Saudi children from infancy to four years of life. A Brief Infant Sleep Questionnaire (BISQ) for sleep assessment was made available to participants through the web link in Arabic language and were filled by the mothers. The target population we...

 Open Access DOI:10.23937/2469-5769/1510058

Methotrexate Associated Toxicity: An Alarming Benign Entity

Cristiana F Martins, Bruno Loureiro, Catarina Magalhaes, Isabel Rodrigues, Monica Costeira, Ana Maia, Augusto Ferreira, Catia Sousa and Tereza Oliva

Article Type: Case Report | First Published: February 13, 2020

An 11-year-old girl with lymphoblastic lymphoma, who presented a history of leukoencephalopathy, which mimicked stroke one week after receiving high doses of intravenous methotrexate. The patient’s symptoms completely improved within two days without sequels. Ten days after a new administration of methotrexate presented right-side hemiparesis and dysarthria. Again, with full resolution. Brain magnetic resonance scan was indispensable for diagnosis. The patient was discharged home without neuro...

 Open Access DOI:10.23937/2469-5769/1510057

Quality of Prevention of Mother-To-Child Transmission of HIV Service at South Wollo Zone Governmental Hospitals, Amhara Region, Ethiopia, 2018

Debrnesh Goshiye, Girum Sebsebie and Sisay Gedamu

Article Type: Research Article | First Published: October 16, 2019

Prevention of Mother-to-Child Transmission service is expanded out in accelerated fashion throughout Ethiopia with all public hospitals and health centers. However, published studies on the services' provision in the country are generally limited. If at all, they did not comprehensively examine quality of the services. The aim of the study was to assess the quality of Prevention of Mother-to-Child Transmission service at governmental Hospitals of South Wollo Zone, Amhara Region, Ethiopia, 2018. ...

 Open Access DOI:10.23937/2469-5769/1510056

Intervention for Non-verbal and Minimally-Verbal Individuals with Autism: A Systematic Review

Lynn Kern Koegel, PhD, Katherine M Bryan, BA, Pumpki Su, MA, Mohini Vaidya and Stephen Camarata, PhD

Article Type: Review Article | First Published: September 27, 2019

Most children diagnosed with ASD will present with late onset verbal communication, and at least one third of these children will remain minimally or completely nonverbal throughout their lifespan, speaking few or no words. Challenges with verbal language can negatively affect many areas, including socialization, academics, independent living and employment. The objective of this paper was to systematically review interventions for the treatment of nonverbal and minimally verbal individuals with...

 Open Access DOI:10.23937/2469-5769/1510055

Signal Processing Technique for Identifying Pacifier Artifacts in Pediatric Sleep Lab Airflow Data

Padmini Selvaganesan, Michala Dauterman, Ajay Mahajan and Jyoti Krishna

Article Type: Research Article | First Published: September 16, 2019

For diagnosing sleep apnea, patients are required to stay overnight in a sleep lab, and various physiological signals are recorded using different sensors. The data collected during the study is often prone to artifacts due to various reasons and one such artifact in younger patients is due to the use of pacifiers which corrupts the signal from the sensors. One of the sensor signals which is corrupted frequently is the airflow signal. This airflow signal is obtained using a thermistor that is pl...

 Open Access DOI:10.23937/2469-5769/1510054

Use of the Electrical Stimulation Therapy in the Lower Esophageal Sphincter for the Treatment of Gastroesophageal Reflux Disease in Paediatric Patients, Two First Cases Reported

Rodrigo Hipolito Cifuentes, Rene Carmona Barba, Antonio Vega Valdes and Placido Espinosa Rosas

Article Type: Research Article | First Published: July 18, 2019

One female patient, on chronic acid-suppressive therapy who underwent successful laparoscopic implantation of the LES stimulation system, surgery time 1 hour, trans surgical endoscopy with absence of perforation, closure of pillars; measured by GERD daily symptom diaries the patient symptoms improved soon. Two weeks after the surgery, the patient reported better symptom control without the intake of PPI, and the absence of heartburn and regurgitation. One month follow-up with esophageal ph shows...

 Open Access DOI:10.23937/2469-5769/1510053

A Questionnaire Survey on Parent's Awareness Regarding Childhood Neurodevelopmental Disorder

Bishnu Prasad Mandal, Yao Yang and Jingyi Fan

Article Type: Research Article | First Published: April 24, 2019

Neurodevelopmental disorders (NDDs) are growing worldwide in both developed and developing countries. Parents are primary caregivers to recognize the signs and symptoms of children's behavior or mental -illness. This study is to obtain basic knowledge and awareness about NDDs in children in Nepali community. People in Nepali community have various religions and outdated belief. This study analyzes misconceptions and factors that influence the knowledge regarding NDDs among general populations, w...

 Open Access DOI:10.23937/2469-5769/1510052

Five Years Survival Trend and Outcome among HIV Infected Children Followed Up in the Pediatric Department in a Tertiary Hospital

Adedemy JD, Agbeille MF, Agossou J, Noudamadjo A, Kpanidja G, Aisso U, Chabi Biaou A, Lalya HF, Seydou L and Koumakpaï-Adeothy S

Article Type: Original Article | First Published: April 08, 2019

HIV infection still contributes significantly to high leatlity among infant and child. The aim of this work was to assess survival rate after five years of routine follow up among HIV 1-infected children in the pediatric ward of the Parakou Teaching Hospital. It was a descriptive cohort study with analytical purpose covering Five years from 2011 to 2016. It focused on 89 HIV 1-infected children. Kaplan-Meier method was used to estimate the survival probabilities. The survival trends were compare...

 Open Access DOI:10.23937/2469-5769/1510051

Baby Walker Use and Child Development


Article Type: ORIGINAL ARTICLE | First Published: March 06, 2019

The study was conducted in İstanbul University İstanbul Medical Faculty Social Pediatric Outpatient Clinic. Children aged 18-30 months who used BW for 30 minutes or more a day for at least 1 month constituted the user group (n = 100) and those who never used a BW were in the control group (n = 100). Information was obtained through the personal health record of the unit and by a face-to-face questionnaire applied to the families during their visits to the unit. The Ankara Development Screening...

 Open Access DOI:10.23937/2469-5769/1510050

Looking toward the Future: An Inquiry into the Acceptance of a Hypothetical Laboratory-based Screening Test for Autism Spectrum Disorder

Jane M DeLuca, PhD, RN, CPNP-PC, Sara M Sarasua, PhD, MSPH and Luigi Boccuto, MD

Article Type: ORIGINAL RESEARCH | First Published: February 23, 2019

Currently, a clinical diagnosis of autism spectrum disorder (ASD) is determined by behavioral/ observational evaluations performed on children ages 2-5 years. Research suggests that laboratory-based tests for screening or diagnosis of ASD may be available in the future. In this study, we examined attitudes towards the acceptance of a hypothetical laboratory-based screening test for children for ASD. For this study, a survey was developed to capture opinions about a hypothetical ASD laboratory te...

 Open Access DOI:10.23937/2469-5769/1510049

An Exploration of the Roles of Certified Child Life Specialists & Registered Play Therapists in the United States

Julie Lerwick, PhD, LPC, NCC, RPT

Article Type: Review Article | First Published: February 06, 2019

In the United States pediatric hospitals and healthcare organizations are becoming more familiar with the value of Child Life Specialists to partner with children and their families to offer information, preparation, and stress reduction interventions to ease the potential negative emotional impact of a healthcare experience. To that end, Child Life Specialists have a unique role, which is not often understood by other healthcare providers. Historically casually regarded as "the hospital play la...

 Open Access DOI:10.23937/2469-5769/1510047

D-Penicillamine in the Neonatal Period: Past (!), Present (!?) and Future (?!)

Lajos Lakatos

Article Type: Case Report | First Published: December 01, 2018

D-penicillamine (D-PA) was first recognized as a potential benefit for neonatal hyperbilirubinemia (NHBI) caused by hemolytic diseases of the newborn infant or immaturity of UDP-glucuronyltransferase enzyme. During a long-term follow up study there was a remarkedly low incidence of retrolental fibroplasia (RLF) in the infants treated with D-PA in their neonatal period. Then, all infants < 1500 g birthweight were treated with D-PA to prevent retinopathy of prematurity (ROP). This preventive inter...

 Open Access DOI:10.23937/2469-5769/1510046

Associations between Maturity Status and Dietary Intake in Austrian Adolescents

Clemens Drenowatz and Klaus Greier

Article Type: Research Article | First Published: November 19, 2018

Dietary intake plays an important role in the development and health of children and adolescents. Puberty is a particularly vulnerable period due to the increased nutrient demands associated with growth. This age range has also been associated with various changes in health behavior. While several studies have examined the influence of the social and built environment on dietary habits during adolescence, there remains limited research on the association between biological maturation and eating ...

 Open Access DOI:10.23937/2469-5769/1510045

Acute Necrotizing Encephalopathy in Children: A Case Report and Literature Review

Ping Yuan and Min Zhong

Article Type: Case Report | First Published: November 16, 2018

Acute necrotizing encephalopathy (ANE) is a rare clinical-imaging syndrome with unknown etiology, characterized by acute fulminant severe encephalopathy and brain damage with multifocal symmetry. ANE has no specific clinical symptoms and signs, similar to common encephalitis or encephalopathy symptoms. The characteristic brain imaging examination is diagnostically significant. To date, no specific treatment for ANE is available and the prognosis is poor. Here, we reported a typical case of ANE i...

 Open Access DOI:10.23937/2469-5769/1510044

Childhood Fever Knowledge and Management: A Case of Mothers with Children under Five Years

Reindolf Anokye, Rita Amihere, Patience Abbiaw, Enoch Acheampong, Naomi Gyamfi and Amy Budu-Ainooson

Article Type: Original Article | First Published: November 15, 2018

Most childhood ailments often present with fever which account for the most common reasons why parents seek medical care for their children; particularly, the under-five children. The study aimed to assess the mothers' knowledge of fever in their under-five children and how this is managed at home. This was a descriptive designed study that used a simple random sampling technique to select 100 participants who were mothers of under-five children who presented to the Kwahu Government Hospital, At...

 Open Access DOI:10.23937/2469-5769/1510043

A Novel ATP1A2 Mutation in Pediatric Hemiplegic Migraine

Christopher J Butler and Andrew Mallick

Article Type: Case Report | First Published: November 02, 2018

Migraine is a common pediatric disorder presenting with unilateral frontal headache. Hemiplegic migraine is a rare and clinically challenging subtype of migraine with aura. There are two different subtypes of hemiplegic migraines; they can occur as either sporadic or familial forms. Recently our understanding of the genetics underlying hemiplegic migraine has rapidly evolved. Familial hemiplegic migraine has been associated with pathogenic mutations in three independent genes. Migraine is a comm...

 Open Access DOI:10.23937/2469-5769/1510042

Birthweight and Gestational Age: Early Life Management Strategy to Population Health for Non-Communicable Diseases

Issa Al Salmi and Suad Hannawi

Article Type: Research Article | First Published: October 31, 2018

Non-communicable diseases (NCD) are rising throughout the globe over the last few decades. Developing countries bear the worse burden of these NCD. Similarly, low birthweight is increasing around the world where most of this prevalence commonly seen in the developing countries but as well in the well-developed countries where advancement of health care managed to increase the survival of the very low birthweight babies. In recent years, there has been great interest in the early development of t...

 Open Access DOI:10.23937/2469-5769/1510041

Hemophagocytic Lymphohistiocytosis Secondary to H1N1 Pneumonia: A Case Report

Manoj D, Vinayaka HS and Basavaraj GV

Article Type: Case Report | First Published: October 24, 2018

Hemophagocytic Lymphohistiocytosis (HLH) describes a clinical syndrome of hyperinflammation resulting in uncontrolled and ineffective immune response. It may be primary or secondary HLH. Primary HLH is better defined as "genetic" encompassing both the familial hemophagocytic lymphohistiocytosis (FHL) and also HLH occurring in association with Chediak-Higashi syndrome, Griscelli syndrome type 2 and X-linked lymphoproliferative disorder. FHL is inherited as an autosomal recessive manner. The incid...

 Open Access DOI:10.23937/2469-5769/1510040

Histopathological Fate in the Inguinal Hernia Sac in the Children

Mustafa Yasar Ozdamar

Article Type: Original Research | First Published: October 19, 2018

Obliteration of the processus vaginalis during the fetal growth begins with a transient decrease in sympathetic tonus and then ends with smooth muscle cells (SMCs) undergoing apoptosis. Otherwise, an inguinal hernia (IH) occurs due to the defective obliteration. Although the mechanism in the formation of an inguinal hernia has been elucidated by many investigations, it has not been investigated whether proliferation in the IH sac cells which would lead to the benign or malignant process. In this...

 Open Access DOI:10.23937/2469-5769/1510039

Pediatric Nature of Enteric Fever with Emerging Antibiogram: A Cross Sectional Study

Sameer Sarswat, Mithilesh Kumar and Raju Gupta

Article Type: Original Article | First Published: October 05, 2018

Typhoid fever is a life-threatening systemic infection occurring in developing countries like India. The presenting signs and symptoms of typhoid fever in children differ from adults. Some studies indicate reemergence of sensitivity of Salmonella with chloramphenicol. 164 children between 1-12 years of age with suspected enteric fever were enrolled in the study. Out of these, 73 patients were diagnosed as enteric fever and clinical features were compared among different age groups. Antibiotic se...

 Open Access DOI:10.23937/2469-5769/1510038

Impact of Double Volume Exchange Transfusion on Biochemical Parameters in Neonatal Hyperbilirubinemia

Mohd Ibrahim Wani, Mudasir Nazir, Roumissa Lone, Mohd Rafiq, Syed Wajid Ali and Bashir Ahmad Charoo

Article Type: Research Article | First Published: October 05, 2018

Almost 60% of normal healthy term babies and 80% of preterm babies develop visible jaundice in the first week of life. Although the outcome of the majority is benign, newborns with untreated severe hyperbilirubinemia can develop short and long-term sequelae of bilirubin encephalopathy. This study was designed to evaluate the impact of exchange transfusion on various biochemical parameters and to assess the need for routine calcium gluconate supplementation during the procedure....

 Open Access DOI:10.23937/2469-5769/1510037

Lifestyle, Diet and Body Mass Index in Offspring of Women with Pregestational and Gestational Diabetes

Nurah M Hammoud, Harold W de Valk, Lenie van Rossem, Geertje W Dalmeijer, Douwe H Biesma, Jan M Wit, Maarten Rijpert and Gerard HA Visser

Article Type: Research Article | First Published: October 05, 2018

Offspring from women with diabetes have an increased risk for childhood obesity, which may be related to the abnormal intrauterine environment, genetic imprinting or current diet and lifestyle. We analyzed whether diet and lifestyle differ between offspring from women with either type 1, type 2 or gestational diabetes. We collected completed questionnaires from parents of 51 offspring from women with type 1 diabetes (ODM1), 21 of women with type 2 diabetes (ODM2) and 87 of women with gestational...

 Open Access DOI:10.23937/2469-5769/1510036

Impact of Exclusive Breastfeeding on Digital Sucking in Children Attending the Children's Outpatient Department of University of Uyo Teaching Hospital, Uyo

Oloyede Iso Precious and Okpokowuruk Frances Sam

Article Type: RESEARCH ARTICLE | First Published: September 12, 2018

Sucking of the digits is the most common oral habit found in children. It is a form of non-nutritive sucking which appears to be influenced by various factors. When the habit becomes prolonged, it can lead to both dental and hand complications. Breastfeeding is one of the factors known to be protective against this habit in children. Therefore, the aim of this study was to find out the prevalence of digital sucking in our environment and the influence of breastfeeding/exclusive breast feeding in...

 Open Access DOI:10.23937/2469-5769/1510035

Congenital Cytomegalovirus Infection Presenting as Severe Conjugated Hyperbilirubinemia on First Day of Life

Aaradhana Singh and Ravi Sachan

Article Type: Case Report | First Published: July 12, 2018

Congenital Cytomegalovirus infection (CMV) has varied presentations ranging from asymptomatic to involvement of multiple organ systems like central nervous system, gastrointestinal, hepatic and hematopoietic. Jaundice is a manifestation of congenital CMV presenting as neonatal hepatitis or cholestasis jaundice. We report a case of severe conjugated hyperbilirubinemia presenting on the first day of life that was diagnosed as a case congenital CMV on further workup....

 Open Access DOI:10.23937/2469-5769/1510034

Oral Status of a Pediatric Patient with Merosine Negative Congenital Muscular Dystrophy

Livia Roberta Piedade De Oliveira, Ivete Pomarico Ribeiro De Souza and Carla Martins

Article Type: Case Report | First Published: June 22, 2018

Merosine Deficient Congenital Muscular Dystrophy (MDCMN) is a rare subtype of Muscular Dystrophy and it is defined as generalized hypotonic muscular syndrome. This case report aimed to describe the oral status of a six-year-old girl with MDCMN. The family's and child's chief complaint was bad breath. The child, who presented normal intelligence, had physical disability with mobility impairment and so, used wheelchair....

 Open Access DOI:10.23937/2469-5769/1510033

Decompressive Craniectomy in Pediatric Severe Head Trauma

Angel J Lacerda Gallardo, Daysi Abreu Perez, Miguel Mazorra Pazos, Gustavo P Valdivieso Caraguay, Gustavo M Obregon Criales and Paschal Edes Songoro

Article Type: Research Article | First Published: June 11, 2018

To evaluate in a general way the usefulness of early decompressive craniectomy in pediatric patients with severe traumatic brain injury, the time elapsed from the moment of trauma to the arrival at the neurotrauma center, Glasgow coma scale on admission and its possible association with discharge results and evaluate the results of the computerized tomography images on admission and sequential, as well as the behavior of intracranial pressure and cerebral perfusion pressure....

 Open Access DOI:10.23937/2469-5769/1510032

Serum 25(OH) Vitamin D Levels of Adolescent and Young Medical Students

Asli Derya Kardelen, Ismail Yildiz, Beyhan Omer and Fatma Oguz

Article Type: Research Article | First Published: May 30, 2018

Vitamin D has an important role in many parts of the body, it maintains serum calcium (Ca) and phosphorus (P) homeostasis and is necessary for the health of bones and muscles. It also has positive effects on the immune system. It has a protective effect against hypertension, cardiac disease, various cancers, type 1 diabetes, autoimmune and allergic diseases....

 Open Access DOI:10.23937/2469-5769/1510031

Ventilator-Associated Pneumonia Caused by Klebsiella Pneumoniae in Preterm Newborn Infants

Kushnareva МV, Markhulia Kh М, Keshishyan ES and Semenov AV

Article Type: Research Article | First Published: March 19, 2018

Severe pneumonia had 10 infants, moderate stage was among 4 infants, an acute stage was observed in 12 patients, and prolonged stage was in 2 infants. Severe form of the disease was presented by pronounced symptoms of infectious toxicosis, respiratory and cardiovascular insufficiency, physical changes from the lungs. Bronchopulmonary dysplasia was developed in two infants....

 Open Access DOI:10.23937/2469-5769/1510030

The Different Approaches of Single Lung Ventilation in Infants with Pulmonary Malformation

Costanza Tognon, Luisa Meneghini, Francesco Fascetti Leon and Piergiorgio Gamba

Article Type: Original Article | First Published: February 17, 2018

Since many years, feasibility and safety of thoracoscopic surgery in infants with pulmonary malformations has been confirmed. Nevertheless, infants present some problems caused by the anatomical and physiological peculiarities typical of the age and of the size of the structures. Several ways to overcome these difficulties have been proposed to assure efficacy and safety of mono-pulmonary ventilation. The knowledge of the infant's respiratory physiology is essential to prevent complications and ...

 Open Access DOI:10.23937/2469-5769/1510029

Impact of Early Childhood Developmental Intervention Programs: Cost-Benefit Analysis Using a Proposed Model

Aravindhan Veerapandiyan, Lama Charafeddine, Durriyah Sinno and Mohamad A Mikati

Article Type: Research Article | First Published: January 31, 2018

Early Childhood Developmental Interventions (ECDIs) were developed with the aim of improving overall functional outcome of children over and above what the home environment provides. Cost-Benefit Analysis (CBA) of ECDIs using a flexible and easy to apply model that can complement the more granular and highly desirable CBA studies that often may be too difficult or too expensive to perform....

 Open Access DOI:10.23937/2469-5769/1510028

Risk Factors for Hospital Readmission and Follow Up after NICU Discharge of Infants Born at Extremely Low Gestational Age in Metropolitan Melbourne

Tejas N Doctor, Efrant Harnaen, Bob Seith, Kenneth Tan and Simon Craig

Article Type: Original Article | First Published: December 04, 2017

Extremely preterm infants, < 28 week of gestational age, (ELGANs) continue to need high levels of health-care post-discharge from the NICU. We studied post-NICU hospital contacts of this highly vulnerable population and present data from infants treated in our health network....

 Open Access DOI:10.23937/2469-5769/1510027

Intravenous Clonidine: A Useful and Safety Sedation for Critically Ill Children

Carme Alejandre, David Vila, David Vila, Sergio Benito, Patricia Corniero, Monica Balaguer, Susana Segura, Francisco Jose Cambra and Iolanda Jordan

Article Type: Research Article | First Published: December 01, 2017

Critically ill children who are admitted to Pediatric Intensive Care Unit (PICU) often receive analgesia and sedation for pain, comfort and safety. Moreover the new objectives of sedation include maintenance of the functioning of the neuromuscular system early upon ventilatory support....

 Open Access DOI:10.23937/2469-5769/1510026

Association of Increased Maternal Plasma Homocysteine with the Adverse Birth Outcomes Following Prenatal Psychological Stress

Hui Li, Huiping Zhang, Qian Su, Dan yao, Shuya Shao, Ding Ding, Shaoli Wang and Zhongliang zhu

Article Type: Research Article | First Published: March 17, 2017

Disorders in the expression of plasma homocysteine are significantly related to psychological stress. There is also evidence that prenatal maternal psychological stress could lead to adverse birth outcomes. The present study aimed to determine whether disorders in the expression of plasma homocysteine would be associated with the adverse birth outcomes following prenatal psychological stress (PPS)....

 Open Access DOI:10.23937/2469-5769/1510025

Infantile Blount's Disease: Histopathological Changes in the Proximal Tibial Metaphysis. Comparison between Medial and Lateral Specimens

Freek Hollman, Pascal Vroemen, Lodewijk Van Rhijn, Dam Surtel, A Cremers, Paul Rompa, Prosper Moh and Heleen Staal

Article Type: Original Article | First Published: November 05, 2016

This study will present the histological findings of biopsies acquired from the medial and lateral part of the proximal tibia during the W/M serrated osteotomy in patients with infantile Blount's disease. It is hypothesized that the medial metaphyseal area of the proximal tibia will present a different ossification pattern compared with the lateral area....

 Open Access DOI:10.23937/2469-5769/1510024

Developing a Culturally Sensitive Training Program for Recognition of Hypoxic Ischemic Encephalopathy in Rural India

Atul Malhotra, Michael C Fahey, Suzanne L Miller, Graham Jenkin, JV Singh, Pawankumar Patil, Vishwajeet Kumar and Euan M Wallace

Article Type: Research Article | First Published: August 24, 2016

Background: Birth asphyxia is a major cause of neonatal deaths in the developing world. The management of an asphyxiated infant includes effective resuscitation at birth and treatment of subsequent hypoxic ischemic encephalopathy (HIE). HIE is frequently under recognized in this setting and this contributes to early infant mortality and morbidity. Methods: We present the evolution of a HIE recognition training program for rural India. The development of this program involved close community int...

 Open Access DOI:10.23937/2469-5769/1510023

A Valuable Tool to Determine Supraventricular Tachycardia in Children: Trans-Esophageal Electrophysiological Study

Seyma Kayal, Ilker Ertugrul, Vehbi Dogan, Senem Ozgur, Utku Arman Orun and Selmin Karademir

Article Type: Original Article | First Published: August 22, 2016

A total of 132 patients who underwent TEEPS at our institution were included. Demographic features and symptoms of patients were evaluated and the patients were divided into three groups to compare the inducibility of tachycardia: Symptom group was consisting of 91 patients who had symptoms of arrhythmias, Wolf Parkinson White group was consisting of 18 patients who had Wolf Parkinson White pattern on surface electrocardiogram, and Tachycardia group was consisting of 23 patients who had previous...

 Open Access DOI:10.23937/2469-5769/1510022

Endogenic Intoxication and Kidney

Yurieva Eleonora Alexandrovna, Vozdvizhenskaya Ekaterina Sergeevna, Kushnareva Maria Vasilievna and Novikova Natalia Nicolaevna

Article Type: Review Article | First Published: August 19, 2016

The following information about the endogenous intoxication in children (from 2 up to 17 y.o.) with nephrological diseases was presented. Endogenous intoxication as multisystemic pathological condition occurs as the result of action on the organism of toxic substances of endogenous or exogenous origin. It is characterized by the following: a) violation of the barrier function of the organism against toxins, b) violation of transport mechanisms of toxic substances to the organs of their transform...

 Open Access DOI:10.23937/2469-5769/1510021

Super Giant Coronary Aneurysm in an Algerian Boy with Kawasaki Disease

Houda Boudiaf, Manel Gherbi and Moussa Achir

Article Type: Case Report | First Published: July 22, 2016

The patient is a 5-year-old male with findings suggestive of Kawasaki disease. He was treated with intravenous gamma globulin (IVG) and oral aspirin. Because the fever persisted, he received additional IVG and intravenous methylprednisolone. Echocardiography showed diffuse dilatation of the right coronary artery (RCA; 13 mm) and proximal dilatation of the left main coronary artery (LMCA; 8 mm)....

 Open Access DOI:10.23937/2469-5769/1510020

Over-The-Counter Products and Food Allergy in Children

Luis Miguel Borrego, Magna Correia, Ines Mota and Mario Morais-Almeida

Article Type: Case Report | First Published: June 07, 2016

Over-the-counter medicines are available without prescription, allowing for convenience and facilitating self-care. We report a case of an adverse reaction to a pharmaceutical formula for gingival eruption in a child with milk allergy. The objective of this report is to alert health-care professionals regarding the potential threat of over-the-counter formulations to children with food allergy. Over-the-counter (OTC) medicines are available without prescription. As the number of OTC drugs rise, ...

 Open Access DOI:10.23937/2469-5769/1510019

Linear Growth Predicts Acute Post-Transplant Outcomes in Paediatric Liver Transplant Patients

Jillian S Owens, Michele Strom, Farsad Farassati, Krista Van Roestel, Kathryn Chambers, Penni Kean, Megan Carricato, Vicky L Ng, Yaron Avitzur and Glenda Courtney Martin

Article Type: Research Article | First Published: May 24, 2016

Minimal research has been conducted on the effect of nutritional status on acute post-transplant outcomes in pediatric liver transplant patients. The purpose of this study was to determine the effect of pre-transplant nutritional status (height, weight, albumin, hemoglobin, Vitamin A, Vitamin E, Vitamin D, mean corpuscular volume (MCV), calcium, magnesium and phosphorus) on acute post-transplant outcomes (length of hospital stay and infection rate)....

 Open Access DOI:10.23937/2469-5769/1510018

Initial Mental Health Evaluation of Internationally Adopted Youth: Goals and Timing Considerations

Rowena Ng, Jennifer Tang and Maria Kroupina

Article Type: Short Communication | First Published: May 16, 2016

Internationally adopted (IA) children are at a greater risk for emotional, behavioral and adaptation difficulties, relative to typically-developing youth due to the fact that many of them experience severe social-emotional deprivation and other adverse experiences preadoption. Importantly, a disproportionate number of IA children show insecure attachment with caregivers even post-adoption, which has been associated with later problems with affect and behavioral regulation. Notably, research has ...

 Open Access DOI:10.23937/2469-5769/1510017

Single Center Cohort Study about in vitro Effects of Adalimumab and Anakinra on the Cytokine Network in Patients with Oligoarticular and Systemic Juvenile Idiopathic Arthritis

M. Kirchner, B. Robinson, L. Strothmann, A. Sonnenschein and W. Mannhardt-Laakmann

Article Type: Research Article | First Published: March 28, 2016

The oligoarticular juvenile idiopathic arthritis (oJIA) refers to a heterogeneous group of chronic inflammatory joint diseases of childhood and adolescence of unknown aetiology. The oligoarticular subtype is described as a T helper cell-mediated inflammatory disorder, mainly due the large number of activated Th1 cells and the abundance of pro-inflammatory cytokines in the inflamed joint....

 Open Access DOI:10.23937/2469-5769/1510016

Dental Neglect Affecting Oral Health Status in India

Aditi Mathur, Anmol Mathur and Vikram Pal Aggarwal

Article Type: Original Article | First Published: March 26, 2016

The dental treatment is still a night mare for most of the people. Dental neglect have tight bond with dental caries. Dental caries has been called as scourge of modern civilization and is without doubt, one of the mankind's most prevalent chronic diseases. The concept of dental neglect may offer a viable linkage between dental health and the cultural, social and attitudinal factors. Australia's 1993 children's protection act defines neglect as "any serious omission or commission by a person whi...

 Open Access DOI:10.23937/2469-5769/1510015

Lessons Learned from Collecting Cost Data from Physicians for Economic Evaluations: Two Methods Compared

Maria Isabel Roldos and Vanessa Bustamante

Article Type: Case Study | First Published: March 18, 2016

Health care utilization databases rely on the vested commitment of patients and their families, but mainly from medical care personnel to provide information of diagnoses, procedures, and follow-up visits. Most developed countries produce health care utilization data from hospital and physician sources through large studies funded by federal research monies. In developing countries, these databases are scare....

 Open Access DOI:10.23937/2469-5769/1510014

Interrater and Intrarater Reliability Using Prechtl's Method of Qualitative Assessment of General Movements in Infants

Joanne S. Katz and Agnes Perenyi

Article Type: Original Research Article | First Published: January 15, 2016

Due to the recent advances in obstetrical and neonatal intensive care, an increasing number of preterm infants survive. The surviving infants have high risk for often multiple morbidities, repeated hospitalizations after discharge and adverse neurodevelopmental (ND) outcomes. Several studies suggest improvement in early neurodevelopment in some of the subgroups of preterm infants. Other authors report no improvement or unchanged ND outcomes, especially in very preterm infants....

 Open Access DOI:10.23937/2469-5769/1510013

A Clinical Comparison of Hospitalized Pediatric Patients with Influenza A(H1N1)Pdm09 Virus Infection of the Years 2009/10 and 2012/13

Lukas Schroder, Mark Born, Marcus Panning, Anna Maria Eis-Hubinger, Andreas Muller, Rainer Ganschow and Ingo Franke

Article Type: Original Article | First Published: December 31, 2015

The A(H1N1)pdm09 virus is a major pathogen causing acute respiratory diseases (ARD) in children worldwide, leading to high rates of ambulatory consultations and hospitalizations. The seasonal influenza of 2012/2013 in Germany was unusually severe, leading to higher numbers of hospitalization rates as compared with previous seasons. This trend was even notable in our tertiary care Children's Hospital at the University of Bonn, Germany....

 Open Access DOI:10.23937/2469-5769/1510012

Subacute Metacarpal Osteomyelitis in a Child

Hamdi Kaziz, Thabet Mouelhi, Walid Osman, Mohamed Amine Triki, Nader Naouar and Mohamed Laziz Ben Ayeche

Article Type: Case Report | First Published: December 26, 2015

Subacute osteomyelitis is a rare affection. Clinical presentation is often unclear and can lead to a delay in diagnosis. As a matter of fact, subactue metacarpal osteomyelitis is usually missed at the first time, so that some complications may occur like brachymetacarpia or loss of motion. We report a 10 year-old boy, with a subacute metaphyseal osteomyelitis of the second right metacarpal bone. The radiological features can mimic various benign or malignant bone tumours and non-pyogenic infecti...

 Open Access DOI:10.23937/2469-5769/1510011

Foundations of a Smart Toy Development for the Early Detection of Motoric Impairments at Childhood

Maria Luisa Martin-Ruiz, Miguel Angel Valero, Maria Linden, Susana Nunez-Nagy and Angeles Gutierrez Garcia

Article Type: Short Communication | First Published: November 11, 2015

The creation of adequate smart monitoring solutions at home can provide professionals with reliable information about the health status of a child. Furthermore, toys and playing are crucial for the overall development of a human being. Hence, the aim of this research is to improve the exactitude of traditional evaluation methods by embedding sensors into daily life toys that provide professionals with added value supplementary evidence enhanced by Decision Support Systems (DSS). It will be possi...

 Open Access DOI:10.23937/2469-5769/1510010

Characteristics of Pseudomonas aeruginosa Infection in a Tertiary Neonatal Unit

Efrant Harnaen, Tejas N Doctor and Atul Malhotra

Article Type: Case Series | First Published: October 19, 2015

It is a rare cause of neonatal blood stream infections in developed countries and most studies report its occurrence in the setting of an outbreak. We present data from a busy tertiary neonatal intensive care unit in Australia, over a 12-year period. During the study period, we found 6 cases of P. aeruginosa blood stream infection (0.5% of total positive blood culture episodes and 4.2% of total gram-negative culture episodes)....

 Open Access DOI:10.23937/2469-5769/1510009

Folic Acid and Iron Supplementation in Children with Insufficient Diets in a Developed Country, a Randomised Controlled Trial

E J van der Gaag, N Bolk-van Droffelaar, J van der Palen and R Baarsma

Article Type: Research Article | First Published: October 13, 2015

In developed countries, dietary intake of pre-schoolers is sometimes inadequate. Not because of insufficient provisions, but due to picky eating and behavioural feeding problems. Micronutrient deficiency could be a result, but is most of the time difficult to detect due to failing laboratory evaluations. Iron deficiency is the most common detected nutritional deficiency in children; other deficiencies may be present but are also hidden because they cannot always be found in routine evaluations. ...

 Open Access DOI:10.23937/2469-5769/1510008

Leptospirosis Prevalence and Associated Factors in School Children from Valle de Chalco-Solidaridad, State of Mexico

Joel Navarrete Espinosa, MC Beatriz Rivas Sanchez and Dra. Maria Luisa Soriano Rodriguez

Article Type: Research Article | First Published: October 12, 2015

Cross-sectional study in school children 8-12 years of age; Leptospira identification tests (IFI and Dark Field: Microbiology and Parasitology Department, FM-UNAM) were performed and risk factors were researched. Those positive to IFI (cutoff 1: 80) and dark field in blood and urine were considered positives. Prevalence, prevalence ratios, and multivariate analysis were estimated....

 Open Access DOI:10.23937/2469-5769/1510007

Clitoral Hair Tourniquet: A Case Report and Review of the Literature

Lindsey N Zimmerman and Amy J Wagner

Article Type: Case Report | First Published: October 10, 2015

Hair tourniquets are uncommon occurrences in children that can have devastating consequences. They tend to be found on fingers and toes, but have also been reported to involve the genitalia. We present a case of a hair tourniquet involving the clitoris of a child. A high index of suspicion is necessary in order to facilitate early diagnosis and treatment....

 Open Access DOI:10.23937/2469-5769/1510006

Treatment Approach in Teeth with Complicated Crown and Crown-Root Fracture: Three Case Reports

Mehmet Sinan Dogan, Izzet Yavuz, Osman Atas, Abdullah Emre Karaali, Fatih Demirci and Abdulsamet Tanik

Article Type: Case Series | First Published: October 09, 2015

Tooth injuries constitute an integral part of clinical dentistry. Complicated crown fracture and crown-root fracture are the most common injury in the permanent dentition. The success of treatment and prognosis of the traumatized tooth depends on accurate diagnosis and treatment procedures and materials....

 Open Access DOI:10.23937/2469-5769/1510005

Topic: Acute Kidney Injury in Children: 3-Year Data Review from Ghana

Sampson Antwi, Anima Sarfo, Abigail Amoah, Anna Serwaa Appia and Esther Obeng

Article Type: Research Article | First Published: September 14, 2015

Acute kidney injury (AKI) is a relatively common condition encountered in everyday paediatric practice. It remains a significant contributor to preventable deaths especially in resource constraint regions of the world largely due to lack of dialysis services. This 3-year data analysis (2010-2012) was undertaken to determine the aetiology and treatment/mortality outcomes of children with AKI presenting to a Teaching Hospital in Ghana. AKI was defined in this analysis by the RIFLE and KDIGO cri...

 Open Access DOI:10.23937/2469-5769/1510004

A New Outlook on Clinical Course of Juvenile Dermatomyositis - Experience of a Single Center

Krzysztof Orczyk, Joanna Swidrowska, Jerzy Stanczyk and Elzbieta Smolewska

Article Type: Research Article | First Published: April 08, 2015

Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in children. Diagnostic criteria by Bohan & Peter are originally formulated for adults. A wide range of differences in clinical course of dermatomyositis between adults and children has provoked to set a new look at the existing criteria....

 Open Access DOI:10.23937/2469-5769/1510003

Short Lingual Frenulum and Obstructive Sleep Apnea in Children

Yu-Shu Huang, Stacey Quo, J Andrew Berkowski and Christian Guilleminault

Article Type: Research Article | First Published: April 08, 2015

A retrospective study of prepubertal children referred for suspicion of obstructive sleep apnea, found 27 subjects with non-syndromic short lingual frenulum. The children had findings associated with enlarged adenotonsils and/or orofacial growth changes....

 Open Access DOI:10.23937/2469-5769/1510002

Six-Month Therapy with Metformin in Association with Nutritional and Life Style Changes Obesity in Children and Adolescents with Obesity

Maria Cristina Azcona-Sanjulian, Ana Catalan Lamban and Borja Lana Ruiz

Article Type: Original Article | First Published: March 13, 2015

Objective: To assess the effect of metformin on weight, BMI, body fat, and insulin sensitivity in obese children and adolescents. Methodology: The study was prospective, and included 21 patients with obesity (8 male, 13 female) with a mean age of 12.31 (3.87) years. Inclusion criteria were a fat mass percentage (FM%) of over 25% in males and over 30% in females, a BMI of greater than the 95th percentile, and a lack of response to nutritional and lifestyle changes over three months....

 Open Access DOI:10.23937/2469-5769/1510001

Multidetector Row Computed Tomography Evaluation in Pediatric Heart Diseases-Additional Information to Echocardiography and Conventional Cardiac Catherterization

Yasunobu Hayabuchi, Miho Sakata and Shoji Kagami

Article Type: Review Article | First Published: February 20, 2015

Multidetector-row computed tomography (MDCT) scanners are a widely available, accurate, and noninvasive technique for the diagnosis of pediatric cardiovascular disorders. A lots of articles published regarding the usefulness of MDCT mostly describe that it can be an alternative to the invasive catheterization and angiography. The unique diagnostic features of this imaging modality have been largely ignored or disregarded. We presented the pathological conditions that cannot be diagnosed by conve...


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ClinMed Journals Index Copernicus Values

Clinical Medical Image Library: 93.51

International Journal of Critical Care and Emergency Medicine: 92.83

International Journal of Sports and Exercise Medicine: 91.84

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Ophthalmology and Clinical Research: 90.80

International Archives of Urology and Complications: 90.73

Journal of Clinical Nephrology and Renal Care: 90.33

Journal of Family Medicine and Disease Prevention: 89.99

Journal of Clinical Gastroenterology and Treatment: 89.54

Journal of Dermatology Research and Therapy: 89.34

International Journal of Clinical Cardiology: 89.24

International Journal of Radiology and Imaging Technology: 88.88

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Blood Research and Disorders: 88.22

International Journal of Diabetes and Clinical Research: 87.97

New Issues


International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24



Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42



Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69



International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97



Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55