Hearing Threshold Level among Adult Diabetics in South-Western Nigeria
Omoregie J Idugboe, Babatope A Kolawole and Ebidisemene L Totyen
Article Type: Research Article | First Published: November 03, 2018
Among the most common chronic disorders of modern time, diabetes mellitus remains unique because of its multifactorial ramifications. Apart from the well-described association between congenital deafness and maternally inherited type of diabetes mellitus, the relationship between type 2 diabetes and hearing loss has been the subject of debate since Jordao reported a case of hearing loss with incip...
Carotid Sinus Syndrome in a Patient with Symptomatic Abdominal Aortic Aneurysm - A Case Report
Ksenija Stevanovic, Ranko Trailovic, Biljana Kukic, Marko Dragas, Slobodan Cvetkovic and Lazar Davidovic
Article Type: Case Report | First Published: November 12, 2018
Carotid sinus syndrome (CSS) is defined as syncope with reproduction of symptoms during 10s of carotid sinus massage. The etiology of this condition is unknown, patients are usually symptomatic and present with episodes of syncope. Due to the associated marked sinus bradycardia, sinus arrest or severe hypotension, carotid sinus syndrome may be life-threatening. In patients without previous symptoms, CSS must be promptly recognized and treated, otherwise may lead to catastrophic consequences. If symptoms of CSS appear for the first time during urgent symptomatic abdominal aortic aneurysm surger...
Biologics for Osteoporosis: Where Do We Stand?
Tamer A Gheita and Hanan M Fathi
Article Type: Editorial | First Published: November 12, 2018
Osteoporosis is a common disease with wide prevalence, especially in seniors. Fractures induced by osteoporosis not only decrease the patient's quality of life, but also cause heavy financial burden to the society during medical treatment making this major metabolic bone disease a growing health-economic problem worldwide. Estimated annual costs for osteoporotic fractures are between $10 billion and $17 billion in the United States with a provisional estimation by year 2025 to rise up to $25.3. While in the European Union annual estimation costs is $30.9 billion. 70% of these costs in elderly ...
Pembrolizumab Monotherapy in Relapsed Hepatocellular Carcinoma Post Living Donor Liver Transplantation and Sorafenib
Fadi Nasr, Ahmad Al Ghoche, Saada Diab, Janah Maddah, Layal Mansour, Ali kassem and Abd El Karim Gheith
Article Type: Case Report | First Published: November 12, 2018
Despite of the high incidence of hepatocellular carcinoma (HCC), treatment strategies stays restrained. New treatment aspects remain a necessity to improve overall survival of patients. Here, we report for the first time a 2 years complete remission of hepatocellular carcinoma with pembrolizumab after failure of sorafenib and progression after liver transplantation. Immunotherapy became a field of interest in HCC for researchers and clinicians in order to establish new immunotherapy modalities that improve response to treatment of HCC. HCC accounts for more than 90% of all cases of primary liv...
Low Vision Aid for a Patient with the Optic Neuropathy Due to Neuro-Brucellosis
Fatih M Adibelli and Deniz Altinbay
Article Type: Case Report | First Published: November 10, 2018
Brucellosis is a multisystem infectious disease, which still endemic in Middle East, Mediterranean and South America. Bilateral optic neuritis secondary to the meningeal inflammation is very rare complication of brucellosis. Here we present a 13-year-old male patient with the ocular brucellosis who has optic neuropathy, concluded his treatment and low vision aid for the visual impairment. Brucello...
Cardiac Arrest from Life-Threatening Massive Pulmonary Emboli: A Rare Survival Post Thrombolysis
Gregory Taylor, David Piskorowski, Michael Barney and Haidar Al-Saadi
Article Type: Case Report | First Published: November 08, 2018
An acute pulmonary embolism (PE) is relatively common and sometimes fatal, especially if not recognized early and treated accordingly. We describe the case of life-threatening massive PE causing obstructive shock and cardiac arrest, where thrombolysis was successfully administered. The current consensus among the literature indicates that patients with hemodynamic instability secondary to an acute...
Tensor Voting Based Vascular Bifurcation Detection in CT Images of Lung
Ruifang Sun, Jingli Shi and Xuan Yang
Article Type: Research Article | First Published: November 08, 2018
The accurate detection of vascular bifurcations is not helpful for pulmonary vascular disease diagnosis, but vital in (Computed Tomography) CT image analysis and processing of lung. We propose a tensor voting based method for vascular bifurcation detection in CT image of lung, which a vessel enhancement method is firstly proceeding to initially extract vessel structure, on which we perform ball vo...
Neurologic and Renal Outcomes of Elective Proximal Aortic Repair and Current Cannulation Trends
Sahin Iscan and Bortecin Eygi
Article Type: Research Article | First Published: November 07, 2018
Cerebral protection is a big technical difficulty for aortic surgery. Increased use of antegrade cerebral perfusion (ACP) and deep hypotermic circulatory arrest in experienced hands made open surgery of the ascending aorta and aortic arch aneurysms more successful today. The increase in the variety of surgical equipment to provide unilateral and bilateral cerebral perfusion or monitorization, the effectiveness of the cerebral protection instantly decreased the risk of perioperative stroke or postoperative morbidity and mortality. Despite these improvements, there are many problems which affect...
Assessing Iodine Status in Frontline Healthcare
Ciara Wright and Heather Leeson
Article Type: Case Report | First Published: November 07, 2018
Iodine is essential for the synthesis of thyroid hormones and both hypothyroidism and iodine deficiency are prevalent worldwide. Assessing iodine status in the individual is difficult. Spot urine iodine measurement, while readily available, is not accurate. However, combining the clinical picture with a brief dietary history along with this simple measurement may give further insight into the likely iodine requirements of an individual. Supporting nutritional deficiency in subclinical hypothyroidism is proposed to be helpful in reducing possible requirements for pharmacological intervention in...