ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: November 21, 2020

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2469-5807/1510116

A New Grading for Clear Cell Renal Cell Carcinoma: Combined WHO/ISUP Grading System

Nazlı Sena Seker, Ozan Bozkurt, Güven Aslan, Elif Gokce Devecioglu and Emine Burçin Tuna

Article Type: Original Article | First Published: October 22, 2020

Several parameters have been proposed to predict prognosis in renal cell carcinomas. Although the tumor grade is an important prognostic data in the RCC, there is a low correlation between the observers. The aim of this study was to establish a new grading system based on the combination of different tumor grades in the tumor and the resulting data show the relationship with parameters that are prognostic significance. 185 cases of clear cell RCC treated between 2000 and 2013 were included in th...

 Open Access DOI:10.23937/2469-5807/1510115

Antiplasmodial Efficacy of Vernonia amygdalina in Albino Mice Infected with Plasmodium berghei

Olajide Joseph Afolabi and Jimoh Lateefat Oyewole

Article Type: Original Research | First Published: October 22, 2020

Malaria is one of the world’s most serious diseases caused by Plasmodium parasite. It remains the greatest cause of hospitalization and death among human parasitic infections. Over 40% of the world’s population is at risk of malaria and active clinical cases due to Plasmodium falciparium. The study entitled “Antiplasmodial efficacy of Vernonia amygdalina in mice infected with Plasmodium berghei” is aimed at investigating the antiplasmodial activity of the ethanolic leaf exytract of Verno...

 Open Access DOI:10.23937/2469-5807/1510113

A Study of Age-Wise Spectrum of Gastrointestinal Biopsies with Endoscopic Correlation a 5-Year Experience from a Tertiary Health Care Centre in North India

Bushra Siddiqui, Shahbaz Habib Faridi, Durre Shehwar, Saqib Ahmed and Mastakim Ahmed Mazumder

Article Type: Original Article | First Published: October 19, 2020

Endoscopic biopsy is a common procedure performed in the hospital for a variety of benign and malignant lesions of gastrointestinal tract. Endoscopy is incomplete without biopsy and histopathology is the gold standard for the diagnosis of endoscopically detected lesions. This study aims at analysing age-wise spectrum of gastrointestinal biopsies with their endoscopic correlation. A total of 556 endoscopic biopsy specimens from upper and lower gastrointestinal tract were studied retrospectively f...

 Open Access DOI:10.23937/2469-5734/1510120

Multiple Idiopathic External Apical Root Resorption: A Case Report

Mohanad Alsaedi, M Takriti and Ch Splieth

Article Type: Case Report | First Published: October 23, 2020

Idiopathic root resorption of the permanent dentition is a very rare condition which can be diagnosed during routine dental examinations. A 13-year-old German female was referred to the Unit of Pediatric Dentistry regarding fistulas of all her 1st permanent molars as the patient did not have any specific symptoms with regard to her teeth. All the first molars have been affected in a symmetrical pattern due to a massive idiopathic external root resorption. Clinically, the oral hygiene was very go...

 Open Access DOI:10.23937/2469-5734/1510118

Determinants of Dental Caries among Preschool Children in Dessie Town, 2019: A Case-Control Study

Moges Workneh Ayele and Muluken Amare

Article Type: Research Article | First Published: October 12, 2020

The burden of childhood caries in developing countries is continued to be a significant problem and negatively affects the growth of the child. Despite, dental caries is substantially distressing children, there was the paucity of study on associated factors of dental caries in pre-school children in the study situate. A total of 130 cases and 260 controls were integrated into the study. A systematic random sampling technique was used to select schools. Structured questionnaires were used to col...

 Open Access DOI:10.23937/2643-4059/1710022

A Scoping Review of the Association between Smartphone Use and Mental Health among College Students

Jeff Cain, EdD, MS, Jordan L Kelley, PharmD, BCPS and Daniel Malcom, PharmD

Article Type: Case Series | First Published: October 07, 2020

A scoping review of the literature reporting on smartphone use and parameters of mental health from January 2008 to February 2018 was performed for the purpose of summarizing and describing current research findings regarding the association of smartphone use with anxiety, depression, stress, and sleep of college students. The study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses for Protocols 2015 (PRISMA-P 2015) guidelines. Thirty-one articles met protocol crite...

 Open Access DOI:10.23937/2378-2951/1410203

Unexpected Coronary Angiographic Findings in a Patient with Wellens’ Sign

Morris M Kim, MD, Jonathan S Taylor, MD, Jenna S Anderson, MD and Ignatius G Zarraga, MD

Article Type: Case Report | First Published: October 23, 2020

The abnormal electrocardiogram findings of Wellens’ sign that occur in the context of unstable angina are typically associated with significant stenosis in the proximal left anterior descending (LAD) coronary artery. We report an unusual case of a patient who had unstable angina and Wellens’ sign, without significant LAD stenosis. An 81-year-old man with moderate to severe aortic stenosis, hypertension, mild left ventricular hypertrophy, hyperlipidemia, and history of tobacco use presented t...

 Open Access DOI:10.23937/2469-5831/1510030

Two-stage Adaptive Biomarker-Targeted Clinical Trial Design: Non-Parametric Bayesian and MLE Approaches

Huiding Chen, Ao Yuan and Ming T Tan

Article Type: Research Article | First Published: October 14, 2020

Biomarker targeted two-stage adaptive design is used increasingly in early-stage clinical trials in a variety of therapeutic areas including oncology, where the sample size of the trial is re-estimated based on the first stage data. In such trials often the sample size is moderate, and so incorporating prior information and using robust methods are desirable. In this article, to improve upon existing methods using parametric normal models, we propose a nonparametric Bayesian approach for designi...

 Open Access DOI:10.23937/2690-3172/1710009

Cognitive Behaviour Assessment in Chronic Non Specific Low Back Pain: A Narrative Review

Seema Saini, PhD, Devashish Tiwari, PhD, Paresh Golwala, Lata Parmar, PhD and Tushar J Palekar, PhD

Article Type: Research Article | First Published: October 15, 2020

Literature showed that patients with Chronic Low Back Pain (CLBP) have slowed speeds of information processing and working memory. Methods for assessment of cognition behaviour are decisive for the implementation Of Cognitive behavioural therapies. There remains a large component of the adherence process not assessed, while treating non specific chronic Low back Pain, and the known role for treatment appraisals and beliefs necessitating the pursuit of improved assessment methods. The purpose of ...

 Open Access DOI:10.23937/2469-5696/1410058

Coping with Bleeding Disorders

Tony Brown

Article Type: Case Report | First Published: October 14, 2020

Living with a bleeding disorder is something that very few live within the United States. In fact, hemophilia occurs in only approximately 1 in 5,000 live births. There are about 20,000 people with hemophilia A in the US. Hemophilia B is four times less common than hemophilia A. von Willebrand Disease is much more common than both hemophilia A & B which is believed to effect 1% of the population. Von Willebrand disease is estimated to affect 1 in 100 to 10,000 individuals. The 3 common bleeding ...

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