ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3648/1410019

Development of a Comprehensive NGS Workflow for the Analysis of Tumor BRCA1 and BRCA2 Mutations and Large Rearrangements

Zhengwei Dong, Hua Dong, Xiaorong Zhong, Zuxiang Peng, Xuehua Zhu, Yun Sun, Yunqin Chen, Changting Liu, Xiaolu Yin, Guanshan Zhu, Hong Zheng and Yi Gu

Article Type: Research Article | First Published: September 28, 2015

Patients with germ line or somatic BRCA1 and BRCA2 mutations are sensitive to PARP inhibitor treatment. However, current clinical testing of BRCA1/2 is limited to germ line mutations in blood samples. In the present study, we have developed and validated a work flow for BRCA1/2 mutation test in patient tumor samples, which can identify both germ line and somatic mutations. Our approach combined targeted capturing with the BRCA MASTR assay and consequent sequencing using Miseq, a benchtop next-generation sequencing (NGS) platform....

 Open Access DOI:10.23937/2378-3648/1410018

Enhanced Detection of Longer Insertions and Deletions in Clinical Exome Sequencing Improves Diagnostic Yield

Deepali N. Shinde, Jefferey Chen, Soren Fischbach, David J. Salvador, Kelly Farwell, Hsiao-Mei Lu and Sha Tang

Article Type: Research Article | First Published: September 17, 2015

Whole exome sequencing (WES) has been remarkably successful as both a diagnostic and novel gene discovery tool since its introduction to the clinical laboratory in 2011. Where traditional diagnostic methods have been uninformative in discovering the pathogenic etiology in patients, diagnostic exome sequencing (DES) has provided answers for roughly one-third of patients tested, thus contributing to the management of patients' overall healthcare. Single nucleotide variants are generally efficiently identified by DES in well-covered exonic regions....

 Open Access DOI:10.23937/2469-5793/1510016

Patient Health Literacy and Perception of Provider Communication: Is there a Link?

Erin Vaughn, Kristie Hadden and Benjamin Doolittle

Article Type: Research Article | First Published: October 21, 2015

Inadequate health literacy is a common problem that contributes to poor patient-provider communication. Health literacy screening and specific provider communication practices may be important in clinics where patients are at high risk for inadequate health literacy. This study assessed patients' health literacy and their perception of provider communication practices in a primary care residency program clinic serving an urban multi-ethnic population. A convenience sample of 324 patients in an urban-based primary care practice was surveyed for health literacy and their perception of physician ...

 Open Access DOI:10.23937/2469-5793/1510015

Safeguarding Public Health from Higher Education

Doug Dix

Article Type: Perspective | First Published: October 19, 2015

It is common to assume that colleges and universities provide service to the public. In the U.S., these institutions are granted tax-exemption on this assumption. In times long past, education, in itself, may have been a public service. But it isn't that anymore as the unintended consequences of progress degrade human habitat and social fabric. Education for progress could easily do more harm than good....

 Open Access DOI:10.23937/2469-5793/1510014

Getting them off the Path toward Chronic Disease: Understanding One NJ Community College Students' Food Choices and Eating Habits

Gustave Ado

Article Type: Review Article | First Published: October 15, 2015

Researchers has shown that dietary patterns of many college students predispose them to future health problems and the epidemic of overweight and obesity is prevalent among many students in the United States. Getting community college students off the path to diet related diseases such as type 2 diabetes, heart disease, stroke, some cancers and changing their lifestyle choices so they become generally more healthy requires that we understand how they eat, their levels of physical activity, as well as their daily caloric intake, and their interaction with foods....

 Open Access DOI:10.23937/2469-5793/1510013

Provider's Perspectives on Cultural Competence in Ethnically Diverse Primary Care Practices

Mary A Matteliano and Debra Street

Article Type: Research article | First Published: October 14, 2015

This study explores how frontline healthcare providers describe and understand the delivery of culturally competent care to underserved groups in three neighborhood primary health care practices. Data from fifty intensive interviews and observations at three field sites in a multi-year study are analyzed using grounded theory techniques. Findings show that providers used a range of deliberate strategies-from establishing provider/patient concordance, to finessing language issues, practicing cultural humility, being in the trenches and enacting patient advocacy-to bridge cultural gaps with thei...

 Open Access DOI:10.23937/2469-5793/1510012

The Availability of Ultrasound for Infants with Developmental Dysplasia of the Hip in Pennsylvania

Shane Lavin and William Hennrikus

Article Type: Original Research | First Published: October 13, 2015

Currently, The American Academy of Pediatrics (AAP) recommends that serial clinical examinations using the Ortolani and Barlow Technique be performed of the hips of all infants at birth and at well baby examinations until the child is of walking age-about 1 year of life. In addition, the AAP recommends hip imaging with ultrasound (U.S.) at six weeks of life for female infants born in the breech position despite a normal physical examination for hip instability. Lastly, the AAP recommends optional U.S. hip imaging at six weeks of age for boys born in the breech position or girls with a positive...

 Open Access DOI:10.23937/2572-4193.1510007

Nasal Glomangiopericytoma: Case Report and Clinicohistopathologic Overview

Sheldon P. Hersh and William H. Rodgers

Article Type: Case Report | First Published: September 25, 2015

Glomangiopericytoma, also known as sinonasal hemangiopericytoma, is a rare sinonasal neoplasm that commonly occurs during the sixth or seventh decade of life, often presenting with complaints of nasal congestion and epistaxis. Identified in less than 0.5% of all sinonasal tumors, this typically indolent lesion is a different tumor from the far more common and aggressive so-called soft tissue hemangiopericytoma that arises in varying sites throughout the body....

 Open Access DOI:10.23937/2572-4193.1510006

A Rare Clinical Presentation of a Somewhat Common Lesion

Steve Manzon, Malcolm Zola, Jared S Weiner, Rawle F Philbert, Kevin R. Torske, Donald B MacDougall, and Daniel Nadeau

Article Type: Case Report | First Published: September 18, 2015

Clinicians are often faced with diagnosing routine oral and maxillofacial pathology. Experience and training make such tasks relatively easy. Establishing differential diagnoses, and ruling out the most unlikely, usually will lead to an appropriate treatment plan. Occasionally, a pathologic presentation may significantly differ from the expected, and stump even an experienced clinician. It is imperative, when encountering an unknown or unusual lesion, to return to basics and approach the entity with the same systematic work-up approach we were trained to perform since entering residency traini...

 Open Access DOI:10.23937/2469-5777/1510011

Segmental Bone Muscle and Skin Cross Leg Flap for the Treatment of Posttraumatic Infected Segmental Bone Defect in a Child - A Case Report

Piotr Pedzisz, Ireneusz Babiak, Jakub Janowicz and Mateusz Kulig

Article Type: Case Report | First Published: September 21, 2015

A mangled limb in a pediatric patient produces therapeutic dilemma whether to amputate or salvage greater than in adult. We herein present a case of a 10 year old child with high energy injury to both lower limbs. The bone muscle and skin segment of the limb planned for amputation has been used as a 'spare part' for the contralateral shin defect in order to save at least one weight bearing limb. The cross leg flap has been successful. The patient walks without limp using PTB prosthesis....

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