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ClinMed International Library

For the past decade, ClinMed International Library has been at the forefront of publishing cutting-edge research in clinical medicine. Over the last 10 years, we have consistently provided a platform for publishing innovative findings and advancements in medical science.

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.


  Last Updated: April 25, 2024
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-346X/1410112

Proteasome and Autophagy Pathway in Corneal Epithelial Cells with Limbal Stem Cell Deficiency

Fawzia Bardag-Gorce, Michael Di Lorenzo, Robert Niihara, Sarah Sunada, Amanda Laporte, Kavita Narwani, Daileen Cortez, Jeremy Stark, Mynor Garcia, Alissa Diaz, Joan Oliva, Richard Hoft, and Yutaka Niihara

Article Type: Original Article | First Published: February 28, 2020

Immunofluorescent staining showed that both pathways were positive in normal corneal epithelium. However, while proteasome subunits were decreased in LSCD-CEC, autophagy biomarker MAPLC3B and ATG12-ATG5 complex were significantly increased in LSCD-CEC, compared to healthy CEC. These results indicate that LSCD-induced impairment of UPP may cause a compensatory stimulation of autophagy. However, despite autophagy up regulation, damaged and unwanted proteins, such as modified keratin K4 and K13 agg...

 Open Access DOI:10.23937/2572-4010.1510034

Is Revisional Bariatric Surgery Effective as Primary Surgery?

Hakan Seyit, MD and Halil Alis, Professor

Article Type: Research Article | First Published: February 29, 2020

The study included randomly selected 350 PS patients for control group and 35 RS patients for study group. Prospectively-collected patient data were retrospectively reviewed. To measure the efficacy of the procedure, we calculated the excess weight loss percentage (EWL%). Effective weight loss was accepted as more than 50%. The changes in the status of the comorbid diseases, complications (leakage, bleeding and stenosis), weight loss, % excessive weight loss (EWL) and mortality were recorded. To...

 Open Access DOI:10.23937/2572-3243.1510074

Does Emu Oil Have a Role in the Relief of Non-Specific Pain? A Systematic Review of Clinical Trials Involving Emu Oil

David Sherwood, DO, Benjamin Gill, DO, MBA and Derick Schirmer, MS

Article Type: Original Article | First Published: March 13, 2020

Given a previous review on emu oil from 2014, which concluded a lack of clinical trial evidence, these authors set out to summarize the literature with regard to emu oil use for non-specific pain management. Non-specific pain management was selected as Google Trend data suggest that emu oil may be commonly amongst the general population for the treatment of non-specific pain. Using PRISMA guidelines, three randomized, controlled trial studies were identified, which found either no statistically ...

 Open Access DOI:10.23937/2572-4037.1510045

Teaching Communication Skills in Children and Adolescents with Severe To Profound Neurodevelopmental Disorders through Aided-Alternative and Augmentative Strategies

Fabrizio Stasolla

Article Type: Editorial | First Published: March 14, 2020

Children and adolescents with severe to profound neurodevelopmental disorders (e.g., attention deficit hyperactivity disorders, autism, cerebral palsy, rare genetic syndromes) may have intellectual, motor, and sensorial delays. Additionally, they may experience communication difficulties and exhibit isolation, passivity, and withdrawal. Challenging behaviors (e.g., aggression, impulsivity, stereotypic movements, and tantrum behavior) may occur. Their clinical conditions may seriously hamper thei...

 Open Access DOI:10.23937/2469-5696/1410048

Effects of TSH on Erythrocyte Osmotic Fragility: Signaling Pathway

Evelyn Mendonca-Reis, Camila Cristina Guimaraes Nobre, Artur Paes-Chagas, Leandro Miranda-Alves and Clemilson Berto-Junior

Article Type: Original Article | First Published: March 09, 2020

TSH is a peptide hormone synthetized and secreted by pituitary with fundamental importance for thyroid function. TSH receptors are found in other tissue than thyroid playing diverse roles, including erythrocyte. Based on the fact that deformability is one of the most important features of a mature erythrocyte, we aimed to verify if TSH modulates erythrocytes volume and, if does, which signaling is involved in this modulation. Using hemolysis assay, we create a hemolysis curve of erythrocyte in p...

 Open Access DOI:10.23937/2378-3656/1410299

Successful Management of Hyperosmolar Hyperglycaemic State with Oral Hypoglycaemics in a Rural Setting - A Case Report

Jeremy Kay Hock Lee, Aaron Kwun Hang Ho and Lin Ho Wong

Article Type: Case Report | First Published: February 29, 2020

Hyperosmolar Hyperglycaemic State (HHS) is a diabetic emergency which requires prompt restoration of haemodynamic stability due to high early mortality. There is currently no study which recommends the use of oral hypoglycaemics to lower blood glucose levels, due to the high efficacy of parenteral Insulin. We report a case of our management of HHS using oral hypoglycaemics (Metformin and Gliclazide) due to the absence of parenteral Insulin in a rural setting, with remission of symptoms, stabiliz...

 Open Access DOI:10.23937/2469-567X/1510059

Molecular Detection of Human Papilloma Virus Type 16 among Conjunctival Intraepithelial Neoplasia Patients in Khartoum State, Sudan

Hala H Ahmed, Aya A Almtry, Isra M Aidrous, Sara M Ali, Mohamed H Arbab and Ali M Badri

Article Type: Research Article | First Published: February 29, 2020

Many factors like exposure to UV radiation, climatic conditions, genetic predisposition, immunological state and, more recently, the presence of HPV have been implicated in the genesis of some lesions of the conjunctiva, especially the carcinoma. The study was carried out to detect Human Papilloma Viruses HPV type 16 in conjunctival intraepithelial neoplasia patient in Khartoum state, Sudan during the period from March to July 2019. A total of 50 Formalin-fixed paraffin- embedded Samples were co...

 Open Access DOI:10.23937/2474-3658/1510113

A Plausible

Robert Jay Rowen, MD and Howard Robins, DPM

Article Type: Commentary | First Published: March 06, 2020

Many viruses require reduced sulfhydryl groups for cell fusion and entry. Corona viruses, including SARS-CoV-2 (the cause of the condition now named coronavirus disease 2019 or COVID-19), are rich in cysteine, which residues must be intact for viral activity. Sulfhydryl groups are vulnerable to oxidation. Ozone therapy, a very inexpensive and safe modality may safely exploit this critical vulnerability in many viruses, inclusive of SARS-CoV-2. Mainstream medicine has little in its arsenal for vi...

 Open Access DOI:10.23937/2474-3658/1510112

Deferring Antibiotic Prescribing in Nursing Home Residents with Asymptomatic Bacteriuria: A Pilot Educational Intervention

Emilie Kennedy, DNP, CRNP, FNP-C

Article Type: Clinical Research Article | First Published: March 04, 2020

Unnecessary antibiotic use in nursing home patients leads to negative outcomes including the emergence of multi-drug-resistant bacteria, adverse drug events, polypharmacy and higher health care costs. The purpose of this study was to develop and assess the effects of a pilot clinical staff educational intervention on best practices for the management of asymptomatic bacteriuria (ASB) in nursing home residents. A multi-faceted educational intervention program on ASB was provided to Emergency Depa...

 Open Access DOI:10.23937/2378-2951/1410165

Idiopathic Large Pericardial Effusion and Cardiac Tamponade in Children with Down Syndrome

Numra Aleem, MD, Amna Qasim, MD and Ashraf M Aly, MD, PhD

Article Type: Case Report | First Published: February 26, 2020

Pericardial effusions (PE) in patients with Down syndrome (Trisomy 21) have been associated with hypothyroidism, viral infections and malignancies (particularly leukemia). The PE is usually not large enough to cause cardiac tamponade. We report two cases of idiopathic large PE with one of them progressing to develop a cardiac tamponade that required an urgent pericardiocentesis. A 3-year-old female with Trisomy 21 was seen at cardiology clinic for follow up of a small secundum ASD. Patient has b...

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Partnered with ICI World of Journals. Check the Index Copernicus Values of ClinMed Journals

ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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New Issues

VOLUME 10

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 10
VOLUME 10

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 10
VOLUME 9

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 9
VOLUME 10

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 10
VOLUME 9

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 9

Featured Articles

Right Ventricular Mass: A Unique Approach to Tissue Diagnosis

Bistees George, MD, Marina Sharif, MD, Rishi Bolla, BS, Shaheen Muhammad, MD and Stephen Cook, MD

DOI: 10.23937/2378-2951/1410285



Cyclopia, A Rare Congenital Malformation: A Case Report in a Resource-Limited Setting in Sub-Saharan Africa

Therence N. Dingana, Carlson Sama, Nuh T. Zeh, Herbert Fonteh, Achuasah M. Tah-Atam and Gloria Ashuntantang

DOI: 10.23937/2378-3656/1410435



LigaSure for Management of Obstructed Hemivagina with Ipsilateral Renal Anomaly (OHVIRA) Syndrome

Haven Nicole Frazier, DO and Glendell de Guzman, MD

DOI: 10.23937/2377-9004/1410248


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Respiratory and Pulmonary Medicine Editor-in-chief: Prof. Shufeng Zhou

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin