Titanates and Titanate-Metal Compounds in Biological Contexts
Yen-Wei Chen, Jeanie L. Drury, Whasun Oh Chung, David T. Hobbs and John C. Wataha
Article Type: Review Article | First Published: June 13, 2015
Metal ions are notorious environmental contaminants, some causing toxicity at exquisitely low (ppm-level) concentrations. Yet, the redox properties of metal ions make them attractive candidates for bio-therapeutics. Titanates are insoluble particulate compounds of titanium and oxygen with crystalline surfaces that bind metal ions; these compounds offer a means to scavenge metal ions in environmental contexts or deliver them in therapeutic contexts while limiting systemic exposure and toxicity. In either application, the toxicological properties of titanates are crucial....
A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression of Cardiovascular Events in Salt-Sensitive Hypertension
Estela S Estape, Ivette Torres-Negron, Lorena Gonzalez and Manuel Martinez Maldonado
Article Type: Research Article | First Published: May 30, 2015
The Dahl salt-sensitive rat is a well-established model to study essential hypertension. We fist described a subgroup of these rats based on the unique response pattern in systolic blood pressure during the fist weeks of exposure to a high salt diet that included cataract formation. We classified this group as cataractprone Dahl salt-sensitive rat. We also were able to predict and prevent cataract formation in these rats. Further studies showed an inhibition of lens Na, K-ATPase activity which may be in part responsible for the cataract formation....
Oral Health Care to HIV-Infected Children
Gerardo Rivera Silva and Hector R Martinez Menchaca
Article Type: Commentary | First Published: June 25, 2015
The prevalence of oral lesions in human immunodeficiency virus (HIV)-infected children in developed countries is equivalent to 72%, meanwhile in developing countries it equates to 60%. For this reason health professionals should identify and treat the numerous oral manifestations in HIV-infected children. There are several oral lesions that could be present in HIV-infected children....
Lymphoma or Pseudolymphoma, that is the Question
Yasar Albushra Ahmed and Mohamed Fatani
Article Type: Case report | First Published: June 23, 2015
Drug-induced pseudolymphoma syndrome refers to a benign, drug induced lymphocytic infiltrate in the skin that mimics malignant lymphoma histologically, clinically, or both. At times, exposure to medication may result in cutaneous inflammatory patterns that resemble lymphoma. These pseudolymphomatous drug eruptions may resemble either T-cell or B-cell lymphomas....
Giant Cell Arteritis of the Lower Limb Presenting as Peripheral Arterial Disease and Mantle Cell Lymphoma Two Years Later
Sophia Corsava, Savvas Psarelis and Elena Nikiphorou
Article Type: Letter to Editor | First Published: June 09, 2015
A 55-year-old man with a two-year history of peripheral arterial disease (PAD) was urgently referred to rheumatology via the vascular clinic. He was scheduled for a balloon-angioplasty due to bilateral aortoiliac and femoro-popliteal disease and occlusion of the iliac arteries. His past medical history included stent revascularisation of the left external iliac artery, endarterectomy of both right common superficial and deep femoral arteries and a polytetrafluroethylene patch (PTFE) graft....
The Barthel Index: Italian Translation, Adaptation and Validation
Galeoto G, Lauta A, Palumbo A, Castiglia SF, Mollica R, Santilli V and Sacchetti ML
Article Type: Research Article | First Published: June 19, 2015
The Barthel Index (BI) is widely used to measure disability also in Italy, although a validated and culturally adapted Italian version of BI has not been produced yet. This article describes the translation and cultural adaptation into Italian of the original 10-item version of BI, and reports the procedures for testing its validity and reliability. The cultural adaptation and validation process was based on data from a cohort of disabled patients from two different Rehabilitation Centers in Rome, Italy....
The Contribution of Susceptibility-weighted Imaging (SWI) in Occult Cerebral Vascular Malformations in Pediatric Patients
Neslin Sahin, Aynur Solak and Liya Alkılıc
Article Type: Case Report | First Published: May 26, 2015
Occult cerebral vascular malformations (CVM) include cerebral cavernous malformations (CCM), developmental venous anomalies, and cerebral capillary telangiectasias (CCT). Conventional magnetic resonance imaging (MRI) has low sensitivity in visualizing these angiographically invisible low-flow vascular lesions. Susceptibility weighted imaging (SWI), a novel high spatial resolution gradient echo MRI sequence with both phase and magnitude information, is exquisitely sensitive to blood products and small venous structures....
Right Sided Approach for a Pacemaker Insertion in the presence of Persistent Left Sided Superior Vena Cava: A Pacing Challenge
Edupuganti Mohan Mallikarjuna Rao, Hakan Paydak and Jawahar Mehta
Article Type: Case Report | First Published: May 25, 2015
Persistent Left sided superior vena cava is a rare congenital anomaly that can complicate a variety of cardiac procedures. We present a patient where a persistent superior vena cava was encountered unexpectedly during routine pacemaker insertion. The condition was diagnosed on the table and greatly lengthened the operating time. Given the situation and an absence of a pre procedure diagnosis the surgeon had to be innovative and invent approaches to navigate the complex anatomy on the spot....
Symptomatic Cervical Perineural (Tarlov) Cyst: A Case Report
Zibis H. Aristeidis, Fyllos C. Apostolos and Arvanitis L Dimitris
Article Type: Case Report | First Published: May 23, 2015
Introduction: Perineural cysts, also known as Tarlov cysts, are benign cerebrospinal fluid-filled cysts of the spinal cord. They were first described by IM Tarlov in 1938. Case presentation: We describe a Tarlov cyst located in the cervical spine, a location quite rare in literature. The patient is a 44-year-old woman who presented with a 3-week history of radicular symptoms of the right C6 root. A perineural cyst was identified at the C5-6 level after Magnetic Resonance Imaging of the cervical spine....