ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access

Aggressive Complete Hydatidiform Mole Coexistent With A Normal Fetus During Pregnancy: Is There A Correlation Between Outcome, and Serum HCG Levels? A Report on 2 Cases and Review of the Literature
Nathalie Renard, SWA Nij Bijvank, HH De Haan, J van Eyck, JWB de Groot, RHM Verheijen and AJ Kruse
Article Type: Case Series | First Published: June 01, 2016
wo cases of complete hydatidiform mole with coexisting fetus are described. In the first case, the mole of this twin pregnancy displayed an aggressive behavior with early maternal onset of severe pre-eclampsia and lung and liver metastases. The second patient opted for termination of pregnancy prior to a possible onset of complications. Existing literature on this topic is also reviewed, in particular on the role of serum hCG levels to predict a favourable fetal prognosis.

 PDF  Full Article  DOI:10.23937/2377-9004/1410089


 Open Access

Sacral Nerve Stimulation and Fecal Incontinence: Current Uses and Emerging Trends
Jennifer E Hrabe, Brooke Gurland and Tracy L Hull
Article Type: Short Review | First Published: May 21, 2016
Fecal incontinence (FI) is a socially devastating condition affecting both men and women. Patients often suffer in silence, as FI is frequently unreported. It is commonly seen in patients who also experience urinary incontinence (UI). Risk factors for FI include obstetrical trauma as well as increasing age. Until recently, treatment options were limited and consisted of medical therapy or surgical options with limited efficacy or high morbidity. Initially used for UI, sacral nerve stimulation has emerged as a successful treatment modality for FI.

 PDF  Full Article  DOI:10.23937/2377-9004/1410088


 Open Access

Isolated Rectal Laceration Following Normal Spontaneous Vaginal Delivery and Delayed Rectal Hemorrhage
Yuzuru Anzai
Article Type: Case Report | First Published: May 21, 2016
A 37-year-old Para 0 patient underwent an induction of labor due to chronic hypertension. She had a successful normal vaginal delivery but experienced acute cardiovascular collapse immediately following the delivery requiring massive transfusion. She also was found to have an isolated rectal laceration without laceration of anus or anal sphincter. After she was discharged home she presented to the emergency room with rectal hemorrhage 5 days after the initial repair requiring an additional two units of packed red blood cell transfusion. This case is presented for this rare complication of vaginal delivery.

 PDF  Full Article  DOI:10.23937/2377-9004/1410087


 Open Access

Dextroposition of the Heart Reflected Mosaic Fetal Trisomy 18
Mohamed A Satti, Frederico G Rocha, Erin Beaver and Jeffrey M Dicke
Article Type: Case Report | First Published: May 02, 2016
Anatomy scan of a 22 year old prima gravida at 19w4d showed a viable IUP with unilateral choroid plexus cyst and dextroposition of the heart without any other observed structural malformation. Amniocentesis revealed a normal male pattern for chromosomes 13, 18, 21, X and Y by fluorescence in situ hybridization (FISH). However, chromosomal microarray analysis (CMA) for circulating fetal DNA in maternal blood was consistent with mosaic Trisomy 18. The karyotype of cultured dividing cells confirmed 47, XY, +18/46, XY mosaicism.

 PDF  Full Article  DOI:10.23937/2377-9004/1410086


 Open Access

Successful Treatment of A Primary Cervical Diffuse Large B-Cell Lymphoma with Rituximab-CHOP Immunochemotherapy
Diaz-De La Noval B, Hernandez A, Zapardiel I, De-Santiago J and Diestro Tejeda
Article Type: Case Report | First Published: May 02, 2016
We describe a 46-year-old healthy woman with primary extranodal Non-Hodgkin's diffuse large B-cell lymphoma of the uterine cervix Ann Arbor stage IIEA IPI 1. She presented an acute renal failure and severe ureterohydronephrosis successfully treated with 6 courses of chemotherapy based on Rituximab plus Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) with no major side effects.

 PDF  Full Article  DOI:10.23937/2377-9004/1410085


 Open Access

Comprehensive Programme to Prevent Cervical Cancer - the Case of Hungary
Dobrossy L, Oroszi B, Kovacs A and Budai A
Article Type: Case Report | First Published: April 30, 2016
The overall purpose of a comprehensive cervical cancer prevention programme is to coordinate HPV vaccination (primary prevention) and cervical screening (secondary prevention). Harmonization of the HPV vaccination and population screening is expected to reduce the burden of cervical cancer by reducing human papillomavirus (HPV) infections, and detecting cervical pre-cancer lesions and invasive cancer earlier, providing timely treatment. In 2015, 80% of 7th class schoolgirls between 12-13 years of age received HPV vaccination in Hungary. Compliance with the offered screening needs to be increased.

 PDF  Full Article  DOI:10.23937/2469-567X/1510021


 Open Access

Bone Marrow Cells Repair and Regenerate Acute and Chronic Injured Liver without Primary Evidence of Neoplastic Changes
Prakash Baligar, Veena Kochat, Snehasish Mukherjee, Abinaya Sundari T, Vikash Kumar, Zaffar Equbal and Asok Mukhopadhyay
Article Type: Research Article | First Published: May 28, 2016
All major metabolic and synthesis functions of liver are significantly perturbed in case of critical injury. Though liver regenerates by itself following acute injury, this process is impaired in case of chronic injury. In both cases, unless liver is allowed to regenerate by proving appropriate support, either internally or externally, depending up on the extent of injury it ceases to function and transplantation remains the only available treatment option.

 PDF  Full Article  DOI:10.23937/2469-570X/1410034


 Open Access

Short-Course High-Dose Methylprednisolone Induces Differentiation and Apoptosis of Myeloid Leukemic Cells
Gonul Hicsonmez
Article Type: Short Review | First Published: May 28, 2016
Acute myeloblastic leukemia (AML) is characterized by the accumulation of immature myeloid cells, which lose their ability to differentiate into normal mature cells. The initial observations of the possibility of treatment with agents which induce terminal differentiation of myeloid leukemic cells were made by Leo Sachs and co-workers for more than 4 decades ago.

 PDF  Full Article  DOI:10.23937/2469-570X/1410033


 Open Access

Development of Better Treatments for Retinal Disease Using Stem Cell Therapies
Rachel Gater, Dan Nguyen, Alicia J El Haj and Ying Yang
Article Type: Short Review | First Published: May 28, 2016
The retina is a complex, light sensitive tissue layer on the inner surface of the eye, which functions to translate light stimuli into nerve impulses which travel to the brain via the optic nerve. Retinal diseases such as glaucoma, macular degeneration and retinitis pigmentosa can lead to significant vision problems and even blindness. Although there are some existing treatments for retinal disease, current treatments are invasive, need to be regularly repeated and do not have the capability of regenerating the damaged retinal architecture. The demand for more effective treatments for retinal disease is therefore high. Stem cell therapies and tissue engineering techniques for ocular disease have advanced significantly over recent years with promising results.

 PDF  Full Article  DOI:10.23937/2469-570X/1410032


 Open Access

Japanese Crisis of HPV Vaccination
Masayuki Sekine, Risa Kudo, Sosuke Adachi, Manako Yamaguchi, Yutaka Ueda, Tomomi Takata, Akiko Morimoto, Yusuke Tanaka, Asami Yagi, Etsuko Miyagi and Takayuki Enomoto
Article Type: Review Article | First Published: May 30, 2016
Cervical cancer has been increasing in younger generation, especially in 20's and 30's, so it has been a serious problem that the disease leads to loss of fertility as an urgent issue in Japan. HPV vaccine was added to the national list of routine vaccinations for Japanese girls aged 12 to 16 years by law since April, 2013. Three months later, however, the Japanese Ministry of Health, Labour, and Welfare suspended recommendations for HPV vaccination after several reports of possible adverse events.

 PDF  Full Article  DOI:10.23937/2469-5807/1510039


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