International Journal of

Pathology and Clinical ResearchISSN: 2469-5807

Early Online

 Open Access DOI:10.23937/2469-5807/1510088

Proteinuria Level and Associated Changes in Glomerular Podocytes and Renal Tubular Epithelium

Maha M Arafah

Article Type: Original Research Article | First Published: April 29, 2019

The correlation between glomerular podocytes and renal tubular cells involved in handling of leaked proteins and the level of proteinuria was evaluated. Retrospective 22 cases of clinical proteinuria in patients with various glomerulopathies were retrieved and analyzed. Glomerulopathies in the concerned patients were pathologically diagnosed through light and electron microscopic examination of the submitted renal biopsies. Three cases with protein levels in urine within the acceptable normal ra...

 Open Access DOI:10.23937/2469-5807/1510087

Cellular Desmoplastic or Anaplastic Supratentorial Ependymoma with Neuronal Differentiation in Probable Associated to RELA Fusion? Case Report

Martha Lilia Tena-Suck, Armando Ruiz-Trevino, Laura Chavez-Macias, Carlos Penafiel-Salgado and Carlos Sanchez-Garibay

Article Type: Case Report | First Published: April 20, 2019

Cellular Ependymoma is a term losing in the new WHO 2016 criteria, actually are classified as classical or anaplastic or associated to RELA fusion. We presented a rare case report of classical cellular ependymoma in supratentorial location, which presented a neuronal differentiation and desmoplasia in a young man of 29-yr-old, Immunohistochemistry tumor cells expressed Neu-N, Synaptophysin, SNE, α-synuclein, beta tubulin, ubiquitin, neurofilament, D2DR, and GFAP and vimentin. This rare tumor is...

 Open Access DOI:10.23937/2469-5807/1510086

Predictive Value of Cerebrovascular Reserve in Patients with Carotid Artery Stenosis for Choosing Treatment Strategy

Аliev VA, Semenyutin VB and Panuntsev GK

Article Type: Review Article | First Published: April 08, 2019

The choice of treatment of carotid artery stenosis is firstly based on assessment of the degree of stenosis and embologeneity of the atherosclerotic plaque. But even in "good-risk" population it is still difficult to identify the patients who are particularly at high threat of stroke and would most benefit from carotid reconstruction. Along with common criteria numerous studies also focus on a prognostic role of a cerebrovascular reserve (CVR) and its state which allows to carry out more objecti...

 Open Access DOI:10.23937/2469-5807/1510085

Clinical and Genetics Findings in Mobius Syndrome: Role of Hoxa1 and Hoxb1 Mutations

Lineu Perrone Jr, Felipe Perozzo Daltoe, Luiz Carlos Areas Araujo, Fabio Daumas Nunes, Marina Helena Cury Gallottini and Andrea Mantesso

Article Type: Original Article | First Published: January 14, 2019

Mobius syndrome (MBS) is a rare congenital neurological disorder typically characterized by the absence or underdevelopment of the 6th and 7th cranial nerves, causing a loss of facial expression and strabismus. Other cranial nerves may be affected in addition to other structures such as the jaw, limbs, and anterior chest. While the primary cause of MBS has not yet been identified different hypotheses have been enumerated, including a possible genetic alteration. The Hoxb1 gene may be a good cand...

Volume 5
Issue 1