Evaluation of Pathological Parameters of Two-Year Bladder Urothelial Carcinomas in Association with Literature
Mürüvvet Akçay Çelik, MD and Yeliz Kaşko Arıcı
Article Type: Research Article | First Published: April 21, 2022
In this study, it was aimed to evaluate the pathological parameters in cases with bladder urothelial carcinoma diagnosed in our department, and to investigate the relationship between the cases in the literature and age, gender correlation. In our Faculty of Medicine, Department of Pathology, 68 bladder biopsy cases diagnosed with urothelial carcinoma between 2018-2019 were included in the study. The pathology reports of the cases were evaluated retrospectively. According to the one-way chi-squa...
Lung Abscess as a Complication of SARS-CoV-2 Infection Associated with Mucormycosis in a Romanian Patient
Maria Sajin, Florina Almarii, MD, Iona Eliza Gaianu and George Simion
Article Type: Case Report | First Published: April 08, 2022
Formation of lung abscesses after Covid-19 is a newly emerging complication and superimposed mucormycosis infection is quite rare. We report the case of 62-years-old male who developed a lung abscess after being infected with SARS-COV-2. Because of the unresponsiveness to pharmacological treatment and ongoing lung damage, surgical approach was required. This is the case of a 62-years-old patient who was transferred to our hospital for the management of a non-resolving lung abscess. He was treate...
Criteria for Presumptive Diagnosis of IgD Multiple Myeloma
Gurmukh Singh, MD, PhD, MBA
Article Type: Research Article | First Published: March 25, 2022
IgD myelomas constitute about 1% of myelomas, have worse prognosis, have higher association with lambda light chains, and are associated with excess free involved light chains. Standard immunofixation protocols stain only for IgG, IgM and IgA heavy chains. Proper attribution of a monoclonal gammopathy as having a delta heavy chain requires additional testing that is not available in most clinical laboratories. Retrospective review of protein electrophoresis and other laboratory results showed ch...
Diffuse Intestinal Ganglioneuromatosis: A Case Report with Review of Literature
Hussein Kaouk, Josiane Mansour, Layla Abou Khana, Rosy Feghaly and Georges Aftimos
Article Type: Case Report | First Published: February 19, 2022
Intestinal ganglioneuromatosis is a rare neoplastic disease characterized by an important proliferation of Schwann cells, nerve fibers and ganglion cells in the intestinal wall. We present a case of 36-years-old male who presented with abdominal pain, constipation and vomiting of several days duration. On admission, intestinal occlusion was suspected and urgent laparotomy was done during which numerous nodules were found in the small bowel. Eventually, a segment of the bowel was resected and his...
High Expression of RAGE and HMGB1 in Lung Tissue of Decedents with COVID-19 and Diabetes
Yared Tekabe, Anjali Saqi, Geping Zhang, Monica Goldklang and Lynne L Johnson
Article Type: Original Research | First Published: February 17, 2022
Serum biomarker studies on patients with severe COVID-19 lung disease indicate that increased ligands for Receptor for Advanced Glycation End-products (RAGE) and diabetes are risk factors for severe acute respiratory distress syndrome (ARDS). To investigate in situ RAGE expression in coronavirus disease-19 (COVID-19) ARDS, we obtained lung tissue from autopsies performed on COVID-19 decedents with clinical ARDS and corresponding pathology showing diffuse alveolar damage (DAD) both with and witho...