ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library


Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2572-3308.1510035

Thrombocytopenia in a Patient with Severe Combined Immune Deficiency: An Unusual Cause

Farrukh Sheikh, Safiah Sumayli, Hasan Hakami, Agha M Rehan Khaliq, Sulaiman Al Gazlan, Hasan Alrayes, Ghuzayel Al-Dawsari, Riad El Fakih and Rand Arnaout

Article Type: Short Communication | First Published: September 22, 2018

We report the first case of severe intractable thrombocytopenia in a patient with adenosine deaminase deficiency, Severe Combined Immune Deficiency (SCID), necessitating hematopoietic stem cell transplant. This patient developed severe thrombocytopenia from polyethylene glycol adenosine deaminase and needed a hematopoietic stem cell transplant as an adolescent. She did well afterwards, overall. Al...

 Open Access DOI:10.23937/iaos-2017/1710003

Analysis of Principal Stress Projection in Femur with Total Hip Arthroplasty using CT-image Based Finite Element Method

Kosei Fukuoka and Mitsugu Todo

Article Type: Original Research | First Published: September 20, 2018

The research demonstrates a novel three-dimensional finite element analysis to analyze biomechanical changes in a femur with implant. The method uses principal stress projections to determine trabeculae trajectories in the femur. Visual comparisons of the projections of the femurs show areas of cortical and cancellous changes due to changes in tensile and compressive stresses, revealing areas of s...

 Open Access DOI:10.23937/iaos-2017/1710002

Transforming Growth Factor-Beta (TGF-B) Regulates Nerve Growth Factor and Cyclooxygenase-2 Expression in Subsynovial Connective Tissue in Patients with Carpal Tunnel Syndrome

Mitsufumi Nakawaki, Kentaro Uchida, Kenji Onuma, Koji Sukegawa, Toshihide Matsumoto, Gen Inoue, Hiroyuki Sekiguchi and Masashi Takaso

Article Type: Original Article | First Published: September 19, 2018

Carpal tunnel syndrome (CTS) is a common neuropathy encountered in orthopedics. It results from compression of the distal median nerve (MN) within the carpal tunnel. Characteristic complaints of CTS are numbness, paresthesia, and pain in the hand and fingers, often exacerbated at night. This characteristic MN compression results in various degrees of disability. In recent years, elucidation of the...

 Open Access DOI:10.23937/2469-5742/1510043

Pure Primary Small Cell Carcinoma of Urinary Bladder: An Extreme Rarity

Sanjay Kumar, Namita Bhutani, Sant Prakash Kataria and Rajeev Sen

Article Type: Case Report | First Published: September 19, 2018

Small cell carcinoma of the urinary bladder is an extremely rare tumor accounting for less than 1% of all cancers arising from the bladder. Since the tumor is very rare, pathogenesis is uncertain. The tumor shares similar histological features with the small cell carcinoma originating at the other sites in body. However, its similar clinical features like the conventional transitional cell carcino...

 Open Access DOI:10.23937/2474-3690/1510036

Nigerian Citrullus Lanatus Fruit and Seed Juice Reduces Cardiovascular Diseases Modifiable Risk Biomarkers in Normal Experimental Rats

Aminu Ibrahim, Hadiza Babaye, Murtala Ya'u, Kamaluddeen Babagana, Salisu Maiwada Abubakar, Jamila Mashi Ahmad and Abba Babandi

Article Type: RESEARCH ARTICLE | First Published: September 12, 2018

Dyslipidemia and imbalance of electrolytes are among the modifiable risk factors for cardiovascular diseases (CVDs) which cause morbidity and mortality in hypertensive patients. Consumption of fruits and their juices has been shown to be beneficial health wise by lowering risk of coronary artery/cardiovascular diseases, stroke and other degenerative diseases. The lowering effects and protective me...

 Open Access DOI:10.23937/2378-3648/1410037

Combination of Vitamin K2 and Phosphatidylcholine Inhibits Hepatocarcinogenesis via Mir-16 Regulating

Ruicheng Yan, Jianfei Luo, Fusheng Lin, Chao Hu, and Shiqiang Shen

Article Type: ORIGINAL RESEARCH | First Published: September 12, 2018

Vitamin K2 and phosphatidylcholine are two common drugs in clinical treatment. Studies carried out in the past several years demonstrated vitamin K2 and phosphatidylcholine could separately inhibit hepatocarcinogenesis. In this study, we sought to investigate the synergy of vitamin K2 and phosphatidylcholine and the potential mechanism. Multiple assays were performed to evaluate the effect of comb...

 Open Access DOI:10.23937/ijnd-2017/1710003

Amyotrophic Lateral Sclerosis (ALS) Linked to Intestinal Microbiota Dysbiosis & Systemic Microbial Infection in Human Patients: A Cross-Sectional Clinical Study

David A Steenblock, Taruna Ikrar, Andrew S San Antonio, Elfi Wardaningsih and Masoud J Azizi

Article Type: Research Article | First Published: September 12, 2018

Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's disease is a neurodegenerative and neuromuscular disorder characterized by a progressive death of motor neurons & motor paralysis that culminates in death, usually within 3-5 years of diagnosis from respiratory failure due to paralysis. Currently approved ALS therapies are not curative and fail to increase healthy lifespan. The worldwide prevalen...

 Open Access DOI:10.23937/2469-5696/1410032

Expression of Foxp3 and Rorc Genes in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation: Impact in the Development of Acute and Chronic Graft-Versus-Host Disease

Camila Marca de Veiga Cabral, Walter Moises Tobias Braga, Adriano de Moraes Arantes, Jose Salvador Rodrigues de Oliveira, Gisele Wally Braga Colleoni and Fabio Rodrigues Kerbauy

Article Type: ORIGINAL ARTICLE | First Published: September 07, 2018

The aim of this study is to characterize Treg (FOXP3) and Th17 (RORC)-related genes in patients who underwent hematopoietic cell transplantation (HCT) and correlate them with graft-versus-host disease (GVHD) onset and patients' outcome. Fifty-one patients undergoing allogeneic HCT from matched related donors (MRD) were studied. Samples were collected before HCT, at acute (aGVHD) or chronic GVHD (c...

 Open Access DOI:10.23937/2378-346X/1410093

Thorough Perioperative Laser Photocoagulation in Prevention of Neovascular Glaucoma after Vitrectomy for Diabetic Macular Edema

Yuka Aoyama-Araki, Fumiyuki Araki, Tomoyasu Shiraya and Satoshi Kato

Article Type: ORIGINAL RESEARCH | First Published: September 20, 2018

Neovascular glaucoma (NVG) is a severe complication that may follow pars plana vitrectomy (PPV) for diabetic macular edema (DME). The objective of this study was to evaluate the effectiveness of perioperative fluorescein angiography (FA) and targeted photocoagulation of the non-perfused area (NPA) in preventing the occurrence of postoperative NVG....

 Open Access DOI:10.23937/2378-346X/1410092

Giant Sebaceous Cell Carcinoma of Upper Eyelid - Case Report

Santosh Singh Patel, Reshu Malhotra, ML Garg, AK chandrakar and Dhanshree Kalway

Article Type: CASE REPORT | First Published: September 19, 2018

An eighty-year-old patient presented with right upper eyelid mass. Contrast enhanced computed tomography (CECT) showed large heterogeneously enhancing exophytic soft tissue density mass lesion with few hyperdense foci noted involving skin and subcutaneous tissue. An excisional biopsy was performed. A diagnosis of sebaceous cell carcinoma was confirmed on histopathology....

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Featured Articles

Uterine Rupture during Subsequent Pregnancy following Adenomyomectomy - Report of Five Cases and Proposal for Prevention

Masato Nishida, Yasuo Otsubo, Yuko Arai, Ryota Ichikawa, Yuzuru Kondo, Hiroya Itagaki and Miyako Sakanaka

DOI: 10.23937/2474-1353/1510070

Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy

Adam Bittermann, Shuguang Gao, Sabah Rezvani, Jun Li, Katie J Sikes, John Sandy, Vincent Wang, Simon Lee, George Holmes, Johnny Lin and Anna Plaas

DOI: 10.23937/2572-3243.1510049

Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin