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International Journal of

Blood Research and DisordersISSN: 2469-5696

Archive

 Open Access DOI:10.23937/2469-5696/1410087

Geographical Variation of Acute Promyelocytic Leukemia: A Single Center Study from Saudi Arabia

Assem Elghazaly

Article Type: Brief Report | Indexed Archive: Volume 9

There is no obvious underlying cause for de novo acute promyelocytic leukemia (APL). Recently two case studies showed that the virus torque teno mini (TTMV) has a role in the pathogenesis of APL/APL-like disease. Few studies reported seasonal or geographical clustering of the disease. As no local published research addressed the effect of these two factors on the incidence of the disease, we aimed to study the relationship between geographical and seasonal factors and the incidence of APL in the...

 Open Access DOI:10.23937/2469-5696/1410086

A Prospective, Observational Study to Assess Effect of DTT Treatment on ABO Isoagglutinin Titers in O Blood Group Donors

Shweta Ranjan, MBBS, Prashant Pandey, MD, Divya Setya, DNB and Supriya Kumari, MBBS

Article Type: Original Article | Indexed Archive: Volume 9

To determine actual concentration of clinically significant IgG antibodies, there is need to inactivate IgM antibodies. Aim of this study was to study effect of dithiothreitol (DTT) on ABO isoagglutinin titers performed by column agglutination technology (CAT) and conventional tube technique (CTT) and to compare results obtained by DTT treatment. This was a prospective, observational study conducted from October 2018 to March 2020. All consecutive O group donors were included. All samples were c...

 Open Access DOI:10.23937/2469-5696/1410085

A Prospective Observational Study to Compare Heat Inactivated ABO Isoagglutinin Titres Performed by CTT and CAT with Solid Phase Red Cell Adhesion (SPRCA) in O Blood Group Individuals

Shweta Ranjan, MBBS, Prashant Pandey, MD, Divya Setya, DNB and Supriya Kumari, MBBS

Article Type: Original Article | Indexed Archive: Volume 9

Measurement of actual concentration of IgG requires methods like heat inactivation (HI) of plasma. This study was aimed at comparing of heat treated ABO titers performed by conventional test tube technique (CTT) and column agglutination technique (CAT) with HA/SPRCA. This was a prospective, observational study conducted from October 2018 to March 2020. All consecutive O group donors who gave consent for participation were included. All samples were tested by CTT and CAT before and after HI (pCTT...

 Open Access DOI:10.23937/2469-5696/1410084

Iliopsoas Hematoma as Unusually Early Onset of Hemophilia A in a Young Infant

Coppo D, Rossi L, Raffaldi I, Aguzzi S, Castagno E, Ricca I and Bondone C

Article Type: Case Report | Indexed Archive: Volume 9

A 2-month-old infant was admitted for irritability and hypomobility of the left lower limb. Ultrasound revealed a deep hematoma of the iliopsoas muscle and coagulation tests showed increased activated partial thromboplastin time (aPTT). The finding of marked reduction of blood coagulation factor VIII (FVIII) led to the diagnosis of severe Hemophilia A. The infants were promptly put on i.v. factor VIII concentrates, resulting in rapid clinical improvement....

 Open Access DOI:10.23937/2469-5696/1410083

Magnetic Therapy of Anemia Caused by Inflammations

Manfred Fähnle

Article Type: Original Article | Indexed Archive: Volume 9

In my paper I describe the magnetic therapy of anemia caused by inflammations, and I explain the physical processes underlying this therapy. Anemia occurs when there are not enough healthy red blood cells to carry oxygen to the organs of the body. The patients suffering from anemia feel cold, tired and weak. The most common type of anemia is the iron deficiency anemia. Iron produces a substance in the red blood cells then enables them to carry oxygen (hemoglobin)....

 Open Access DOI:10.23937/2469-5696/1410082

Evaluation of Changes in Haemostatic Parameters in Pregnancy and Puerperium in Women attending Antenatal Clinic at Rivers State University Teaching Hospital, Nigeria

Echonwere-Uwikor, B.E, Moore-Igwe, BW, Chukuigwe-Igbere, O.E and Chuku, P.H

Article Type: Original Article | Indexed Archive: Volume 9

This was a cross-sectional study carried out in Rivers State University Teaching Hospital, Port Harcourt with the aim of determining the Changes in Haemostatic Parameters in Pregnancy and puerperium. A total of 500 age-matched apparently healthy women of reproductive age, which consisted of 200 (40%) pregnant women, 200 (40%) puerperium mothers and 100 (20%) non-pregnant women who served as controls were studied. Their ages ranged from 16 to 41 years (mean 27.4 ± 4.3 years)....

 Open Access DOI:10.23937/2469-5696/1410081

Current Trends in Classic Hairy Cell Leukaemia: Aetiology, Diagnosis and Therapy

Udoka Ogobuchi-Odo, MSc, Silas Anayo Ufelle, PhD and Ifeoma Uzoma Agbo, MSc

Article Type: Review Article | Indexed Archive: Volume 9

Hairy cell leukaemia (HCL) is a rare B-cell neoplasm characterized by pancytopenia, splenomegaly and presence of hairy leukaemic B-cells in the bone marrow. Its aetiology is not clear but occupational and environmental factors are possible risk factors....

 Open Access DOI:10.23937/2469-5696/1410080

Under Reported Potentials of Low Foetal Haemoglobin Concentration in Sickle Cell Disease

Yusuf Ishaya Dogonzo, Obinna Charles Ekoh and Thankgod Nnanna Enewor

Article Type: Original Article | Indexed Archive: Volume 9

The liver plays a significant role in the maintenance of health and survival of an individual. Any threat to this important organ is a threat to the existence of life. Hence its protection is vital to survival. Individuals with SCD are at high risk of suffering from liver failure due to events resulting from HbS polymerization....

 Open Access DOI:10.23937/2469-5696/1410079

Correlation between Coagulation Tests Parameter with Padua Prediction Score in Covid-19 Patients at General Hospital of Prof. Dr. R. D. Kandou Manado

Masengi SJR, Lasut P, Hendratta C, Rotty LWA and Haroen H

Article Type: Original Article | Indexed Archive: Volume 9

Coronavirus disease 2019 (COVID-19) was associated with hypercoagulability state, some changes in parameter of coagulation tests, and also cause venous thromboembolism (VTE), which can be predicted with Padua Prediction Score (PPS). In this study, we are going to seek correlation of PPS and some parameter of coagulation tests between mild and moderate - severe COVID-19 patients in isolation room for COVID-19 patients at General Hospital of Prof. dr. R. D. Kandou Manado....

 Open Access DOI:10.23937/2469-5696/1410078

Hemophagocytic Lymphohistiocytosis in A Post Covid-19 Patient with Mds: A Case Report

Ioannis Vasilopoulos, MD, Marina P Siakantaris, MD, PhD, Kalliope Zerzi, MD, Eliana A Konstantinou, MD, John V Asimakopoulos, MD, PhD, Anestis Karapaschalidis, MD, Fotios Panitsas, MD, MSc, Eleni Plata, MD, Maria K Angelopoulou, MD, Theodoros P Vassilakopoulos, MD, PhD and Panayiotis Tsaftaridis, MD, PhD

Article Type: Case Report | Indexed Archive: Volume 9

Primary or secondary hemophagocytic lymphohistiocytosis (HLH) is characterized by immune activation and lifethreatening cytopenias. Causative relationship between a number of pathogens, autoimmune diseases and even hematologic malignancies with secondary HLH (sHLH) have been reported....

Volume 9
Issue 2