Open Access DOI:10.23937/2378-3656/1410237

Low Saturation Readings in a Patient with Congenital Methemoglobinemia Exposed to Patent Blue Dye: A Case Report

Claudia Jong Chie TIEN and Priscilla Hui Yi PHOON

Article Type: CASE REPORT | First Published: September 29, 2018

Pulse oximetry is widely used perioperatively to detect respiratory events. Abnormal haemoglobins such as methemoglobin can result in inaccurate readings. Here we present the clinical challenges of managing a patient with congenital methemoglobinemia who went for surgery involving injection of patent blue dye and subsequently had a prolonged duration of poor saturation readings post-operatively. Differentials include desaturation due to respiratory causes, worsening of methemoglobinemia and dela...

 Open Access DOI:10.23937/2378-3419/1410096

Effect of Surgery and Adjuvant Radiotherapy on Overall Survival for Non-Metastatic Adenoid Cystic Carcinoma of the Head and Neck: A SEER Population Analysis

John S Goodman, Howard R Sanders, Brian J Mitchell, Jeffrey D Bunn, Jason A Call, Robert K Fairbanks, Wayne T Lamoreaux, Aaron E Wagner, Ben J Peressini, Casey Strauss and Christopher M Lee

Article Type: Research Article | First Published: September 21, 2018

Adenoid cystic carcinoma (ACC) is an uncommon histology that develops from major and minor salivary gland tissue. ACC can originate from multiple different organs but is primarily associated with the salivary gland tissue in the head and neck. According to He S, et al., ACC follows an indolent clinical pattern with a tendency for perineural invasion and accounts for three to five percent of all head and neck cancers....

 Open Access DOI:10.23937/2469-5823/1510098

Perceptions of Turkish Nurses and Patients Regarding Individualized Care: A Comparison Study

Dilek Kucuk Alemdar and Yesim Yaman Aktas

Article Type: Original Research | First Published: September 20, 2018

Individualization of care signifies assessing each patient individually, considering patients' clinical characteristics, clinical situation, and personal life situation, and allowing them to have control over their own care decisions. The purpose of this study is to evaluate to what extent individualism is considered from the perspectives of both patients and nurses....

 Open Access DOI:10.23937/2469-5807/1510075

Chromatin Lipid Microdomains

Carmela Conte, Michela Codini and Elisabetta Albi

Article Type: Commentary | First Published: September 19, 2018

In nuclear membrane, the precise relation among these lipids is responsible for maintenance of normal fluidity in no stimulated cells. During rat liver regeneration, in which the cells are stimulated to proliferate, lipid composition and consequently fluidity of nuclear membranes modify, favoring an increase of mRNA transport that...

 Open Access DOI:10.23937/2469-567X/1510043

90-90-90, Epidemic Control and Ending AIDS: Global Situation and Recommendations

Reuben Granich, Somya Gupta and Brian Williams

Article Type: Review Article | First Published: September 17, 2018

Although human immunodeficiency virus (HIV) first came to our attention thirty-seven years ago, the acquired immunodeficiency syndrome (AIDS) which it causes is, without treatment, 100% fatal with devastating consequences for millions of people...

 Open Access DOI:10.23937/2469-5807/1510074

The Study of Ductal Carcinoma In Situ (DCIS) with Microinvasion Using Myoepithelial Markers

Sana Firdous, Anjaneyulu, Daphne Fonseca, Sudha Murthy, Sundaram Challa and CK Naidu

Article Type: Research Article | First Published: September 14, 2018

DCIS is a premalignant condition characterized by proliferation of neoplastic cells within the ducts with intact myoepithelial cell layer and when there is a breach in myoepithelial cell layer it indicates invasion and in both these condition treatment protocols and prognosis is different. Myoepithelial markers can be used to identify breach and hence invasion....

 Open Access DOI:10.23937/2469-5734/1510060

Does the Autologue Fibrin Glue Enhance the Regeneration of Intrabony Defects in Aggressive Periodontitis?

Omer Alperen Kirmizigul, Mustafa Ozay Uslu and Filiz USLU

Article Type: CASE REPORT | First Published: September 13, 2018

Aggressive periodontitis is a rapid periodontal destruction that develops in early and affects systemically healthy individuals. As in all periodontal diseases, the main purpose of aggressive periodontitis treatment is to enable the patient to maintain his function and aesthetics with her natural teeth in optimal health conditions. The most appropriate treatment for this purpose is periodontal regeneration methods. In this case report, regenerative treatment of intrabony defects with xenograft a...

 Open Access DOI:10.23937/2572-4193.1510048

Study of the Suture-Patch Device through the Tongue for Sleep Apnea using Fluid-Structure Interaction Modeling

Yang Liu, Yitung Chen, Woosoon Yim and Robert C Wang

Article Type: RESEARCH ARTICLE | First Published: September 24, 2018

The prevalence of obstructive sleep apnea (OSA) has been growing over the last few decades, but the treatment outcome differs from person to person. Interest in patient-specific modeling has increased substantially. The availability of detailed clinical data together with efficient numerical methods has now made the fluid-structure interaction modeling feasible. The current study uses 3-D two-way fluid-structure interaction to provide simulation results of the sleep apnea symptom in a female pat...

 Open Access DOI:10.23937/iaphcm-2017/1710010

A Test (Test_a)� for the Assessment of Headache

Alessandra De Rose and Roberto Verna

Article Type: Research Article | First Published: September 22, 2018

This report contains the main results of a quantitative research aimed at testing, through the administration of multiple-level questionnaires- patients (n = 2500) and physicians (n = 100), a simple tool for detecting the individual perception of recurrence and the severity of the symptom of headaches and how it is dealt with in terms of drug use and the use of appropriate reference health structures (general practitioner and headache centers). The ultimate goal of the project is to develop a to...

 Open Access DOI:10.23937/2572-3308.1510035

Thrombocytopenia in a Patient with Severe Combined Immune Deficiency: An Unusual Cause

Farrukh Sheikh, Safiah Sumayli, Hasan Hakami, Agha M Rehan Khaliq, Sulaiman Al Gazlan, Hasan Alrayes, Ghuzayel Al-Dawsari, Riad El Fakih and Rand Arnaout

Article Type: Short Communication | First Published: September 22, 2018

We report the first case of severe intractable thrombocytopenia in a patient with adenosine deaminase deficiency, Severe Combined Immune Deficiency (SCID), necessitating hematopoietic stem cell transplant. This patient developed severe thrombocytopenia from polyethylene glycol adenosine deaminase and needed a hematopoietic stem cell transplant as an adolescent. She did well afterwards, overall. Although rare, thrombocytopenia can result from polyethylene glycol adenosine deaminase. Hematopoietic...