Kırmızıgül OA, Uslu MO, Filiz USLU (2018) Does the Autologue Fibrin Glue Enhance the Regeneration of Intrabony Defects in Aggressive Periodontitis?. Int J Oral Dent Health 4:060.


© 2018 Kırmızıgül OA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/2469-5734/1510060

Does the Autologue Fibrin Glue Enhance the Regeneration of Intrabony Defects in Aggressive Periodontitis?

Ömer Alperen Kırmızıgül1, Mustafa Özay Uslu1* and Filiz USLU2

1Department of Periodontology, Inonu University, Turkey

2Department of Orthodontics, Inonu University, Turkey



Aggressive periodontitis is a rapid periodontal destruction that develops in early and affects systemically healthy individuals. As in all periodontal diseases, the main purpose of aggressive periodontitis treatment is to enable the patient to maintain his function and aesthetics with her natural teeth in optimal health conditions. The most appropriate treatment for this purpose is periodontal regeneration methods. In this case report, regenerative treatment of intrabony defects with xenograft and autologue fibrin glue was presented.


A systemically healthy with a history of orthodontic treatment, 23-years-old female patient was referred to our clinic with complaints of infection and mobility in teeth. Localized aggressive periodontitis was diagnosed and intrabony defects were detected as a result of clinical and radiographic examinations. Multiple intrabony defects was detected. Intrabony defects in the mandibula and maxilla were planned to treat with xenograft and barrier membrane after initial periodontal therapy. The usage of xenograft, otogen fibrin glue and barrier membrane were planned to treat the intrabony defect of upper left central incisor tooth. The patient was prescribed antibiotics, anti-inflammatory drug and chlorhexidine gluconate after the operation and sutures were taken at postoperative 10th day. Clinical parameters such as average pocket depth, clinical attachment level, gingival recession and tooth mobility were recorded. Radiographs were taken at baseline, postoperative 3th and 6th month.


Postoperative healing of patient was uneventful. Pocket depth was reduced, and satisfactory bone gain was achieved after treatment.


As seen in this case, clinically successful results can be achieved by using bone grafts with autologue fibrin glue in the treatment of intrabony defects in aggressive periodontitis.