Open Access DOI:10.23937/2643-3885/1710091

A Prospective Study Evaluating Improved Quality of Life and Physical Function in Patients That Underwent Reconstructive Surgery for Charcot Neuroarthropathy Deformities

Jeffrey D Loveland, DPM, FACFAS, Bezawit Wodajo and John M Zanella, MS

Article Type: Original Article | First Published: July 07, 2025

Charcot neuroarthropathy can lead to severe deformity of the foot and ankle, which can adversely impact affected individuals. Surgical reconstruction may preserve the foot and ankle along with improved function, but it is uncertain if surgical success translates to patient perception of improved health-related quality of life. Patient-reported outcome measures are tools that collect information directly reported by patients regarding their perceptions of health, quality of life, or functional st...

 Open Access DOI:10.23937/2469-5793/1510164

Increasing Capacity for HIV Testing in Davao, Philippines: An Interdisciplinary Training Approach to Improve Equity in the HIV Care Continuum

Danielle A. Walker, Charlyn T. Gambe, Kristianna M. Altamirano, Maria Teresa C. Requillo, Sarah J. Templeton, Isabelle D. Unger, Isabella E. Smith, Angelina Rosalez, Dasha D. Alexander and April Ulloa

Article Type: Research Article | First Published: July 22, 2025

A community assessment was conducted and stakeholders were identified based on accessibility to services for women and natural integration within operations. Invitations to the training were extended to the groups identified. Participants included representatives from three universities, two nonprofit organizations, local clinics, two social work programs, a midwifery practice, three religious organizations, and local tribal leaders. The comprehensive HIV education, counseling, and testing train...

 Open Access DOI:10.23937/2572-4061.1510063

Epidemiological Study of Illicit Drugs Consumed in Côte d'Ivoire Trends Over Recent Years

Bahi Gnogbo Alexis, Meite Souleymane, Kouassi Serge K, N'Guessan Jean Luc A, Konan Jules K, Boyvin Lydie, Kipre Guede Bertin3, M'Boh Gervais M, Dosso Mireille and Djaman Joseph A

Article Type: Original Article | First Published: July 22, 2025

This study aims to establish an inventory of illicit drugs consumed in Côte d'Ivoire and to monitor consumption trends over recent years. Two levels of biological testing were used in this study: Nal von minden Drug-Screen® qualitative tests for screening and Roche Diagnostics THC II semi-quantitative tests for tetrahydrocannabinoid (TCH) quantification....

 Open Access DOI:10.23937/2474-3690/1510078

Evaluating the Sflt1 Mouse Model of Preeclampsia: Benefits and Limitations for Understanding Human Disease

David Aronoff M, Jean Wassenaar W and Meena Madhur

Article Type: Review Article | First Published: June 21, 2025

Preeclampsia (PE) remains a leading cause of maternal and neonatal morbidity and mortality globally. Among several experimental models developed to interrogate the pathogenesis of PE, the mouse model employing systemic infusion or transgenic overexpression of soluble fms-like tyrosine kinase-1 (sFlt1) has gained widespread use due to its capacity to induce cardinal features of the human disease. These include maternal hypertension, renal injury, endothelial dysfunction, placental abnormalities, ...

 Open Access DOI:10.23937/2572-4010.1510052

An Analysis of the Relationship between a Novel Weight Loss Contract, Weight Loss Protocols, and Actual Weight Loss

Jake Tran, Vince Ly, Yenice Zapata, Robert J Wong, Adla Tessier and Robert G Gish

Article Type: Original Article | First Published: June 20, 2025

In this study, we aim to determine the impact that compliance with weight loss protocols can have on weight management for patients after initial staging of metabolic dysfunction–associated steatohepatitis (MASH) and metabolic dysfunction-associated steatotic liver disease (MASLD)....

 Open Access DOI:10.23937/2469-5858/1510159

Gerontology: A Tool for Exploring Social Inequities in Health Across the Life Course

Juan Ramon Almejo Vargas and Irma Fabiola Diaz Garcia

Article Type: Original Article | First Published: June 16, 2022

Social inequalities in health accumulate throughout people's life trajectories and negatively impact the iraging. To this end, an instrument was developed to measure them. The method used was the design and validation of an instrument that initially consisted of 100 items. It underwent expert validation, reducing it to 77 items, and concluded with an exploratory factor analysis that resulted in 11 latent items to measure the phenomenon....

 Open Access DOI:10.23937/2469-5734/1510174

Prevention of Food-Related Gingival Abrasion with use of Denture Adhesive: Results from a Pilot Randomized Controlled Crossover Trial

Malgorzata Klukowska, Julie Grender, Jeffery Milleman and Kimberly Milleman

Article Type: Retrospective Observational Study | First Published: May 25, 2025

This was a 2-treatment, 2-period, examiner-blind, crossover, randomized, controlled pilot clinical trial involving 10 adults with a full maxillary and/ or mandibular denture opposed by natural or artificial dentition and a history of food particle infiltration. For each 3-day treatment period, participants were assigned to use an optimized calcium/zinc partial salt of polyvinyl methyl ether/maleic acid (Fixodent Professional) DA (applied in a continuous pattern) or no adhesive. Participants cons...

 Open Access DOI:10.23937/2469-5718/1510274

Spontaneous Pneumomediastinum in an Adolescent with Muscle Dysmorphia

Hafize H Kahya, Melis Pehlivanturk Kizilkan and Sinem Akgul

Article Type: Case Report | First Published: July 14, 2025

We report the case of a 16-year-old boy with muscle dysmorphia who presented to the emergency department with sudden-onset chest pain and was diagnosed with pneumomediastinum. Etiology was attributed to elevated intrathoracic pressure during strenuous weightlifting exercises, combined with dietary restrictions that may have weakened the alveolar walls....

 Open Access DOI:10.23937/2572-3235.1510135

Enhancing Pulmonary MRI Imaging through an Ann-Based Approach

Bouharati Imene and Bouharati Khaoula

Article Type: Original Research Article | First Published: June 26, 2025

Despite improvements in the morphological quality of lung images in recent years, using ultra-short echo time sequences, the low signal-to-noise ratio caused by the low proton density of lung tissue and cardiac and respiratory motions that cause artifacts have been the cause of limitations in magnetic resonance imaging (MRI). Spatial resolution and diagnostic quality are then reduced. This is mainly evident in emergency situations of pulmonary embolism or in chronic bronchopulmonary diseases....

 Open Access DOI:10.23937/2469-5734/1510173

Alveolar Ridge Preservation Using Clot and Dense Polytetrafluoroethylene Membrane (PTFE-d): A Novel Surgical Protocol and Clinical Case Report

Dusan Marinkovic, Francisca Collao, Consuelo Tello and Claudio Miranda

Article Type: Case Report | First Published: July 07, 2025

This study presents a biologically driven, minimally invasive protocol for alveolar ridge preservation (ARP) using autologous blood clot and dense polytetrafluoroethylene (PTFE-d) membranes. After tooth extraction, alveolar bone undergoes significant resorption, particularly in the first three months. The ARP/PTFE-d technique aims to stabilize the blood clot three-dimensionally, protect the healing socket from soft tissue invasion, and promote targeted osteogenesis through a biologically active ...