Open Access DOI:10.23937/2378-3419/1410174

Malignant Neural Sheath Tumors of the Head and Neck

Carlos Santiago Ruggeri, Gabriel Rondón Gonzalez, Ana Clara Ragoni and Inés Fagalde

Article Type: Research Article | First Published: August 19, 2022

Malignant neural sheath tumors located in the head and neck region are very rare. Surgical treatment if possible is the best option, trying to obtain wide resection margins free of tumor. To determine the incidence of malignant tumors of neural histology, in relation to nerve tumors originating in the head and neck and description of two clinical cases....

 Open Access DOI:10.23937/2378-3656/1410401

Perspectives in the Treatment of Crohn’s Disease by a Physician of Family Medicine: A Clinical Case Presentation

Luka Vučkič, Eva Zadravec, Igor Rakuša and Mateja Rakuša

Article Type: Case Report | First Published: August 19, 2022

Crohn’s disease is a rare disease with a chronic relapsing course. Usually begins at a young age influenced by environmental, genetic, and immunological factors. Patients mostly have only intestinal changes. In addition to the gut, other organs, such as skin, joints, liver, and kidneys can be affected. The type of treatment and choice of drugs depends on the type and severity of the disease....

 Open Access DOI:10.23937/2572-4193.1510128

Earmold Impression Material Foreign Body in the Middle Ear as a Hearing Aid Impression Complication: A Case Report

Hawa SK, MD, SK Azura, B. Audiology, Halimahtun SS, MS ORL-HNS, Noorizan Y, MS ORL-HNS and Khir MA, MS ORL-HNS

Article Type: Case Report | First Published: August 19, 2022

Hearing aid is an electronic device fitted to the ear and designed to amplify and deliver sound to the ear. Upon fitting a hearing aid, patients are required to make an earmold impression material for device fixation based on patient’s personal preference, the shape and texture of the ear. Complications while making an earmold for hearing aids are rare but during this process, the impression material can be accidentally entered in the middle ear through a perforation on the tympanic membrane.....

 Open Access DOI:10.23937/2474-3658/1510276

Toxicity and Antiplasmodial Assessments of Chromolaena odorata Leaf Extract on Plasmodium berghei-Infected Mice

Confidence Ogechi Nworgu, Kinsley Elele and Elias Adikwu

Article Type: Original Article | First Published: August 12, 2022

This study assessed the toxicity and antiplasmodial profile of the ethanolic leaf extract of Chromolaena odorata on Plasmodium berghei-infected mice. The extract was screen qualitatively and quantitatively for phytochemical constituents. Adult Swiss albino mice (20-23 g) of n = 5/group were inoculated with Plasmodium berghei intraperitoneally and were orally treated with the extract (250, 500 and 1000 mg/kg) and...

 Open Access DOI:10.23937/2572-4061.1510045

In vitro and in vivo Evaluation of the Toxicity Roots of Leptadenia hastata (PER) Decne. Cytotoxicity on Caco2 and HepG2 Cells, Acute and Sub-acute Toxicity on Wistar Rats

Fatoumata Bah, Pascale Marie Aimée Dozolme, Mama Sy Diallo, Ramadhan Nyandwi, Mohamadou Lamine Daffé, Aminata Touré, Absa Lam, Mathilde Cabral, MatarSeck, Serge Maria Moukha and Mamadou Fall

Article Type: Research Article | First Published: August 10, 2022

Nowadays, the use of medicinal plants, for treatment of several pathologies, continues to gain grounds throughout the world. Leptadenia hastata, like other medicinal plants, is used as therapeutic agent for several pathological conditions including diabetes mellitus, diarrhoea, and prostatitis, among other, however, limited data on its toxicity are available....

 Open Access DOI:10.23937/2474-3658/1510275

Re-Emergence of Monkeypox in Sierra Leone, a Challenge for Clinicians in a Developing Country, 2021: A Case Report

Paul Mansaray, Adel Hussein Elduma, Leonard Hakizimana, Kassim Kamara, Alden Henderson and Gebrekrstos Negash Gebru

Article Type: Case Report | First Published: August 11, 2022

Monkeypox is an emerging zoonotic disease with potentially serious illness with similar symptoms as smallpox but with the distinguishing symptom of lymphadenopathy. On March 9, 2021, health authorities in the Koinadugu District in Sierra Leone reported a suspected case of monkeypox. We investigated this case to confirm the diagnosis, and to identify the source of infection and risk factors, and institute control measures....

 Open Access DOI:10.23937/2378-3516/1410179

Laryngeal Foreign Body for 20 days without a Catastrophic Event

Ved Narang, Sambiagio Giovanni and Balaji Natarajan

Article Type: Case Report | First Published: August 22, 2022

We present successful management of an unusual foreign body (FB) case in the larynx for 20 days. A 45-year old man presented with complaints of hoarseness of voice and coughing up a few pieces of silver-colored flakes. He had unresolved dyspnoea and wheeze for three weeks and was managed as an asthmatic with partial resolution of symptoms....

 Open Access DOI:10.23937/2469-5750/1510115

Evaluation of A Novel Topical Formulation for The Treatment of Problematic Skin: Results of An Italian Clinical Study

Alice Casari, Rima Al Sibai, Michela Mediani, Monica Molinari and Walter Fiore

Article Type: Original Research | First Published: August 11, 2022

Problematic skin conditions such as atopic dermatitis, acne vulgaris, and psoriasis are directly linked to microbial imbalance or ‘dysbiosis’. Alterations of skin microbial communities along with other contributing factors, cause skin barrier dysfunction triggering immune and inflammatory responses....

 Open Access DOI:10.23937/2469-5750/1510114

Pseudoxanthoma Elasticum

Youssef Zemmez, Ihssane Hallab, Abir Boulhilat, Adil Elkhoyaali, Jaouad El azhari, Hasna Kerrouch, Rachid Frikh, Mohamed Boui and Naoufal Hjira

Article Type: Case Report | First Published: July 16, 2022

Pseudoxanthoma elasticum (PXE) is an inherited disease of elastic tissue primarily affecting the skin, eyes, and arteries. We report a clinical case to emphasize the need for early diagnosis and follow-up, a multidisciplinary approach and the management of complications. A 62-year-old patient consulted for wrinkled layers of papules typically “shagreen”. The skin lesions were disseminated throughout the body but predominated in the folds, abdomen and neck....

 Open Access DOI:10.23937/2378-3397/1410144

Analyzing Letters to the Editor Guidelines of Major Surgery Journals: A Brief Report

Morgan Garrett, Brayden Rucker, Max Bouvette and Matt Vassar

Article Type: Research Article | First Published: August 06, 2022

Peer review is the process by which an author’s work is subjected to critical evaluation by experts in the same field [1]. A survey performed in 2016 by the Publishing Research Consortium showed that 82% of researchers were in agreement that “without peer review, there is no control in scientific communication” [2]....