Paediatric systemic lupus erythematosus (pSLE) is an autoimmune disease with multiple manifestations resulting in inflammation & damage to several organs. We report a case of young boy presented to us with features of meningoencephalitis with multisystem involvement....

Herein is a case of systemic lupus erythematosus (SLE) who developed myasthenia gravis (MG) and presented with proximal muscle weakness and easy fatiguability. Although inflammatory polymyositis is a common cause of muscle weakness in SLE, MG is not frequently reported in SLE. The diagnosis was established by positive Antibodies to acetylcholine receptors, Electroneuromyography (ENMG). Her computed tomography (CT) scan of the chest showed nodular soft tissue in the anterior mediastinum. She was ...

The records of eighteen patients were analysed retrospectively. The median age of diagnosis of NPSLE was 33.5 years. The median duration of SLE at the time of the neuropsychiatric manifestations was 4.5 months. Thirty-three percent had NPSLE as the first presentation of SLE. The most frequent clinical presentation was acute confusional state (30.8%) followed by cerebrovascular disease (23.1%) and seizures (19.2%). Seven patients (38.9%) had more than one neuropsychiatric syndrome. The commonest ...

Calcium pyrophosphate deposition (CPPD) disease is caused by calcium pyrophosphate (CPP) crystal deposition in the fibrocartilage. It usually presents as monoarticular deposition but can deposit in multiple joints presenting as chronic polyarticular disease mimicking rheumatoid arthritis (RA), known as pseudo-rheumatoid arthritis, making it very challenging for the correct diagnosis. We are presenting a case of a 64-year-old female presented with chronic polyarticular disease refractory to disea...