Case Report Open Access

Endobronchial Lipoma in a Never-Smoker

Li Wang, Meenakshi Bansal and Guang-Qian Xiao
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: Endobronchial lipomas, usually found in the obese and in smokers, can cause patients significant distress with chronic cough, chest pain, dyspnea, and increased infection risk. Here we present a case of a 61 year-old obese, never-smoker gentleman who initially presented with chronic productive cough, hemoptysis, chills and night sweats; and was later found to have a right upper lobe lung parenchymal lesion. Biopsy demonstrated a picture consistent with obstructive endobronchial lipoma.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410036

Editorial Open Access

Important Considerations for Providers Regarding the Use of Electronic Cigarettes

Lucinda England, Joseph G. Lisko and R. Steven Pappas
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: The use of electronic nicotine delivery systems such as electronic cigarettes has increased considerably in recent years among youth and adults. While the majority of adult electronic cigarette users are current conventional cigarette smokers, an increasing number of adolescents who have not previously smoked are using use electronic cigarettes. Despite these trends, many health care providers report feeling uninformed about the health risks associated with the use of these products. For example, in a study of 615 Minnesota physicians and nurse practitioners caring for adolescent patients, Pepper and colleagues found that most respondents reported having low levels of knowledge and comfort discussing electronic cigarettes with patients, and nearly all expressed the wish to learn more.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410035

Case Report Open Access

An Unusual Case of Left-Sided Massive Biliothorax

Maria Jose Soler-Sempere, Nuria Vicente-Ibarra and Laura Heredia-Oliva
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: Biliothorax and pleurobiliary fistula are rare complications secondary to biliary tree diseases. We report the case of a patient with left massive pleural effusion secondary to biliothorax without fistula or ascites. To our knowledge, this is the first case to be described with left side biliothorax.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410034

Research Article Open Access

Distinct Sex-Specific Gene Expression Changes in the Placenta in Association with Childhood Allergy

Astrud R Tuck,Luke E Grzeskowiak, Annette Osei-Kumah, Zarqa Saif, Suzanne M Edwards, Andrew Tai, Susan L Prescott, MeriTulic, Richard Saffery and Vicki L Clifton
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: The prevalence of allergic disease has risen significantly during recent years. A major component of the susceptibility to allergic disease is determined in prenatal life, when the placenta plays a central role in fetal growth and development. In this study, we aimed to identify the patterns of gene expression in the placenta that may program early immune function to increase susceptibility to allergy.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410033

Case Report Open Access

Iatrogenic Tracheal Rupture - The Role of a Thoracic Surgeon

Nikolaos Panagiotopoulos, Mohamed. A Gulamhussein, Davide Patrini, Rajeev Shukla, Martin Lees, Martin Hayward, Shyamsunder Kolvekar and David Lawrence
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: Iatrogenic tracheal rupture following intubation is a rare, but potentially lethal complication. Usually patients present with the classical symptoms of mediastinal subcutaneous emphysema and respiratory distress. However, the timing or the onset of these symptoms is quite variable and differs between patients.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410032

Review Article Open Access

Genetics and its Associated Pathways of Pulmonary Arterial Hypertension

Rui Fan, Daniel Penny and Yuxin Fan
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: Pulmonary arterial hypertension (PAH) is a devastating disease with significantly reduced survival. To date, no tested therapies have demonstrated an ability to reverse or cure the disease. The etiology of PAH is heterogeneous and incompletely understood. Genetics plays an important role in idiopathic and heritable PAH. Many germline gene mutations have been described as promoters of PAH and include mutations in the gene coding BMPR2, which has been identified in at least 50% of familial and 10-40% of sporadic cases.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410031

Case Report Open Access

A Pain in the Neck: A Pott's Disease Case Study

Caitlin Naureckas, Jonathan Movson and E Jane Carter
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: A 21-year-old Guatemalan male presented with six months of headaches and neck pain. MRI of the cervical spine demonstrated multiple inflammatory processes, both within the paraspinal soft tissue as well as within the bone itself, including the appearance of total destruction of C1. Microbiologic confirmation of Mycobacterium tuberculosis was made by fine needle aspiration. The patient was treated medically with appropriate anti-tuberculosis therapy coupled with aggressive pain control and careful neurological follow-up.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410030

Original Research Article Open Access

Respiratory Symptoms and Lung Function among Danish Construction Workers. A Cross-Sectional Study

Dorte Jessing Agerby Hanskov, Charlotte Brauer, Nina Breinegaard and Lilli Kirkeskov
Int J Respir Pulm Med Volume 2, Issue 4

Abstract: This study investigated whether Danish construction workers had an increased prevalence of chronic obstructive pulmonary disease (COPD) or affected lung function and if the prevalence differed between types of jobs within construction.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410029

Volume 2
Issue 4