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Case Report Open Access

Case Report: Laryngocele- A Rare Cause of OSAS and Respiratory Distress

Shlomo Merchavy and Nadav Bartal
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: Laryngocele is rare condition in which dilation of the laryngeal saccule that extends upward the false vocal cord, is filled with air, and is in communicating with the laryngeal lumen1. It can presents as neck mass or as cystic lesion in the neck. Awareness regarding this rare entity can help the physician in making the correct diagnosis.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410028

Research Article Open Access

Outcomes of Moderate-Severe Community-Acquired Pneumonia in Patients with Diabetes Mellitus: Impact of Systemic Steroids and Time to First Dose of Appropriate Antibiotic Therapy

Mazen S. Bader, Kassem Abouchehade, Annie A. Brooks, Yanqing Yi
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: In patients with diabetes mellitus (DM), community-acquired pneumonia (CAP) is associated with significant morbidity and mortality. The primary objective of the study was to describe the clinical outcomes and risk factors for moderate-severe CAP in hospitalized patients with DM. Methods: We conducted a retrospective cohort study of 156 hospitalized patients with DM and moderate-severe CAP at two tertiary medical centers.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410027

Research Article Open Access

A Study to Determine the Level of Knowledge, Attitudes and Practices on the Cause, Treatment, Prevention and Control of ILI Infections

Philip M Muthoka, Dismas Ongore and Mary Kinoti
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: ILI infections are infections of the human respiratory tract. They are caused by various viruses including corona viruses, adeno-viruses, influenza virus types A, B and C, among others (CDC- US, 2005). When these infections are circulating within the community, patients with ILI infections who have both cough and fever within 48 hours of symptom onset are likely to have influenza (A or B) infections. In Kenya, these infections cause significant morbidity leading to a lot of lost time of productive work and school absenteeism for children.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410026

Case Report Open Access

Differentially Expressed Proteins in Response to Resuscitation of NonCulturable Cells of Mycobacterium tuberculosis H37Rv: Potential New Drug Targets

Ravi Kr. Gupta, Bhavnesh Kumar, Deepa Bisht, Kiran Katoch, Kalyan Mitra and Ranjana Srivastava
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: The major obstacle in TB eradication is attributed to the dormant state of the TB bacilli, Mycobacterium tuberculosis and is characterized by asymptomatic, non-culturability and antibiotic resistant state of disease. Conventional antibiotic therapy is only applicable to the active form of the disease. These non-replicating cells can resume the growth in immunosuppression state and cause the symptomatic disease.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410025

Original Article Open Access

Discharge Care Bundle for Patients with Acute Exacerbations of COPD: Benefit more likely to be seen beyond 30 Days

Shorofsky M, Lebel M, Sedeno M, Zhi Li P and Bourbeau J
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: Background: COPD is associated with significant morbidity, mortality, and hospital costs. The implementation of COPD 'discharge care bundles' has been proposed as having an impact on readmissions. We developed and implemented a discharge care bundle and the aim of this study was to evaluate its effects on utilization of hospital services in a real life setting. Methods: We conducted a retrospective chart review study from 2007-2013 to evaluate utilization of hospital services over three time periods (30, 90 days, and one year) post discharge care bundle implementation in two patient cohorts. The first cohort included patients who had utilized any hospital service in the previous year for respiratory complaints and the second included only those who had been admitted.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410024

Original Article Open Access

Chronic Rhinosinusitis is Associated with Airflow Obstruction in Japanese Never-Smokers without Asthma

Keita Matsumoto, Tomotaka Kawayama, Takashi Kinoshita, Shuwa Minami, Kazuko Matsunaga, Masako Nagafuchi, Tomoaki Hoshino and Toru Rikimaru
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: Background: The relationship between chronic rhinosinusitis (CRS) and airflow obstruction is still unclear. This cross-sectional study was conducted to investigate whether CRS is an independent risk factor for airflow obstruction in never-smokers without asthma. Methods: One hundred fifty-eight subjects aged ≥ 40 yr without asthma were divided into 4 groups: 22 never-smokers with CRS, 27 smokers with CRS, 69 never-smokers without CRS, and 40 smokers without CRS. Subjects with airflow obstruction were compared among the groups, and the correlation between CRS severity and airflow obstruction was investigated.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410023

Case Report Open Access

Management of a Refractory Malignant Pleural Effusion in a Patient with Small Cell Lung Cancer: A Case Report

Maria M Wilczynska and Helen E Davies
Int J Respir Pulm Med Volume 2, Issue 3

Abstract: Malignant pleural effusion (MPE) is a common presenting feature of underlying malignancy and frequently results in debilitating symptoms. In chemosensitive malignancies, such as lymphoma, small cell lung or ovarian cancers, chemotherapy is often considered the fist line treatment, however if unsuccessful, pleural intervention to achieve fluid control is required. This may include therapeutic thoracentesis, chest drain insertion, thoracoscopy, chemical pleurodesis, and use of an ambulatory indwelling pleural catheter (IPC) or a combination of the above procedures.

PDF   | Full Text   DOI: 10.23937/2378-3516/1410022

Volume 2
Issue 3