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Rheumatic Diseases and TreatmentISSN: 2469-5726

Archive

 Open Access DOI:10.23937/2469-5726/1510040

MR Imaging of Degenerative Cartilage Lesions of the Knee Joint in Floor Layers and Graphic Designers

Soren Rytter, Birthe Lykke Thomsen, Birgitte Schutt Christensen and Lilli Kirkeskov

Article Type: Research Article | Indexed Archive: Volume 2

Kneeling work leads to an additional risk of developing knee osteoarthritis (OA). Previous studies have primarily been based on radiography, but radiography is limited by its inability to visualize articular cartilage, in which the earliest signs of OA occur. The objective of this explorative study, based on available data, was to examine the prevalence of magnetic resonance imaging (MRI)-detected knee cartilage lesions in male floor layers exposed to kneeling work, as compared to non-exposed ma...

 Open Access DOI:10.23937/2469-5726/1510039

Implementation of Evidence-Based Practice in Rheumatology: What Sociodemographic, Social Cognitive and Contextual Factors Influence Health Professionals' Use of Research in Practice?

Neher M, Stahl C, Festin K and Nilsen P

Article Type: Research Article | Indexed Archive: Volume 2

Research on the use of research in rheumatology practice is largely lacking. This study attempts to fill this knowledge gap by exploring the degree to which evidence-based practice (EBP) is implemented in clinical rheumatology practice and identifying individual and organizational factors that may potentially affect research use in the clinical environment....

 Open Access DOI:10.23937/2469-5726/1510038

Impact of the Addition of Ginger Extract and Copper Sulphate to Glucosamine Sulphate on Il-1Beta-Stimulated Chondrocytes

Francis Rousset, Laurent Grange, Minh Vu Chuong Nguyen, Clara Pinosa-Zezza, Philippe Gaudin, Thierry Conrozier, Francoise Morel and Bernard Lardy

Article Type: Research Article | Indexed Archive: Volume 2

This study provided experimental evidence that glucosamine sulfate decreases ADAMTS5 expression and apoptosis. In addition, ginger root and copper sulphate decreased pro-MMP1 expression by regulating NOX4 activity. Our data suggest the implication of Heme Oxygenase-1 in the molecular mechanisms....

 Open Access DOI:10.23937/2469-5726/1510037

Chronic Large Joint Synovitis in Systemic Lupus Erythematosus: Finding What You Look For

B Hodkinson, I Okpechi and SA Botha-Scheepers

Article Type: Case Report | Indexed Archive: Volume 2

A 30-year-Black African female was diagnosed with SLE when she presented with a Coombs positive haemolytic anaemia, lymphopenia, polyarthritis, oral ulcers and a malar rash. Her antinuclear antigen (ANA) was positive, she had hypocomplementaemia and she was HIV negative. She was commenced on oral corticosteroids (initially high dose 60 mg/day and later weaned to 15 mg daily), chloroquine sulphate and azathioprine. Her blood counts and SLE symptoms improved. Four months after diagnosis, she devel...

Volume 2
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