Open Access DOI:10.23937/2469-5807/1510163
Immunohistochemistry Does Not Improve Reliability of Diagnosis of Lymphovascular Space Invasion in Endometrial Cancer
Mazdak Momeni, Michael Chary, Ann Tran, Pouya Javadian, Vaagn Andikyan, Tamara Kalir and Konstantin Zakashansky
Article Type: Research Article | Indexed Archive: Volume 11
Lymphovascular space invasion (LVSI) predicts nodal involvement, progression-free survival, and overall survival in patients with endometrial cancer. Despite its importance, the current approach to determining LVSI relies on slide review, which has substantial variability across pathologists. This variability is clinically important because it may alter the recommendation for treatment with radiation. Our study investigates whether immunohistochemical counterstaining to mark the border of t...
Open Access DOI:10.23937/2469-5807/1510162
Spindle Cell Papillary Thyroid Carcinoma (SC-PTC): A Rare and Challenging Case in Thyroid Pathology
Mellouki Abderrahmane, Evrard Niyonkuru, Reda Chelly, Meriem Regragui, Mehdi Karkouri and Mohamed Mahtar
Article Type: CASE REPORT | Indexed Archive: Volume 11
Spindle cell PTC (SC-PTC) is an exceedingly rare PTC subtype believed to have a favorable prognosis. However, a clear and precise definition of SC-PTC is still lacking. Currently, spindle cells in SC-PTC are regarded as a form of metaplasia, wherein follicular carcinomatous cells transform into mesenchymal-like cells devoid of papillary nuclear features. We report the case of a 45-year-old woman diagnosed with spindle cell PTC. The patient presented cervical swelling that progressed gradually ov...
Open Access DOI:10.23937/2469-5807/1510161
Pulmonary Hyalinizing Granuloma: A Rare and Challenging Case
Mellouki Abderrahmane, Jalloul Imad, Mouadib Salah, Labied Mohamed, Karkouri Mehdi, Boubia Souhail and Ridai Mohammed
Article Type: Case Report | Indexed Archive: Volume 11
Hyalinizing Pulmonary Granuloma (HPG) is a rare pseudoneoplastic pulmonary lesion requiring histopathological diagnosis, often challenging for pathologists. We present the case of a 54-year-old woman with an incidental HPG diagnosis....