Open Access DOI:10.23937/2378-346X/1410030
Retinitis Pigmentosa: Disease Encumbrance in the Eurozone
Vaidya P and Vaidya A
Article Type: Research Article | First Published: July 28, 2015
Retinitis Pigmentosa (RP) is the most common hereditary progressive retinal degenerations and is fist cause of irreversible blindness in developed countries among persons under 70 years of age. It is characterised by progressive degeneration of the retinal photoreceptors. The objective of this review was to determine the burden of RP in the Eurozone....
Open Access DOI:10.23937/2378-346X/1410029
Treatment of a Pseudoxanthoma Elasticum Patient Initially Presented with Choroidal Neovascularisation Secondary to Angioid Streaks
Muhammed Sahin, Alparslan Sahin, Harun Yuksel, Umit Peker and Fatih Mehmet Turkcu
Article Type: Case Report | First Published: July 20, 2015
Pseudoxanthoma elasticum (PXE) is a rare, systemic disease with typical ophthalmological findings including angioid streaks (AS) (represent breaks in the Bruch's membrane). A serious and common complication of AS is the development of choroidal neovascularization (CNV), which can result in significant and irreversible vision loss. The introduction of intravitreal agents that inhibit vascular endothelial growth factor (VEGF) has improved outcomes in patients with CNV. In this paper we aimed to pr...
Open Access DOI:10.23937/2469-5718/1510014
Effect of Hypercapnic Severity on Plasma Ammonia Accumulation and Respiratory Exchange Ratio during Incremental Exercise
Takahide Kato, Takaaki Matsumoto, Atsuko Tsukanaka, Masataka Nakano, Ryo Ito, Masato Amano, Marc Cole and Stanley M Yamashiro
Article Type: Original Investigation | First Published: July 20, 2015
Blood lactate (La) and ammonia (Am) concentrations are widely accepted markers of metabolism not only in clinical studies but also during exercise. Elevations from normal resting levels of both are observed in exercise and associated with deleterious effects such as fatigue. A decrease in blood La concentration during exercise under hypercapnic conditions was previously reported, and La threshold (LT) was unchanged by hypercapnia....
Open Access DOI:10.23937/2378-346X/1410028
Acute Ophthalmic Artery Occlusion as Initial Manifestation of Acquired Immunodeficiency Syndrome
Gowtham Jonna, Matthew SJ Katz, David M Rubaltelli, David C Gritz and Peter L Gehlbach
Article Type: Case Report | First Published: July 20, 2015
Purpose: To report the first case of acute ophthalmic artery occlusion as initial manifestation of Acquired Immunodeficiency Syndrome (AIDS) in context of marked Human Immunodeficiency Virus-1 (HIV-1) viremia and otherwise negative work-up. Methods: Report of a 25 year-old previously healthy man who presented to a hospital-based tertiary care referral center with acute, monocular vision loss. Complete ophthalmologic examination, fluorescein angiography, and full systemic evaluation were performe...
Open Access DOI:10.23937/2469-5734/1510010
Immediate Implant Placement in the Infected Site with Presence of a Pre-Existing Cyst: Report of Two Cases
Binbin Yu, Chun Fan, Ximei Xiao, Jiajia Song, Chenglong Ji and Chunyang Zhang
Article Type: Case Report | First Published: July 24, 2015
This report showed that the placement of immediate implants in presence of a pre-existing infected cyst may not be necessarily contraindicated if appropriate clinical procedures like antibiotic administration, meticulous cleaning, and alveolar debridement are performed before implant surgical procedure. Immediate placement of implants for replacement of teeth with the pre-existing infected cysts is a predictable treatment and can be indicated for replacing teeth lost. This report regards the imm...
Open Access DOI:10.23937/2378-3516/1410023
Chronic Rhinosinusitis is Associated with Airflow Obstruction in Japanese Never-Smokers without Asthma
Keita Matsumoto, Tomotaka Kawayama, Takashi Kinoshita, Shuwa Minami, Kazuko Matsunaga, Masako Nagafuchi, Tomoaki Hoshino and Toru Rikimaru
Article Type: Original Article | First Published: July 22, 2015
Background: The relationship between chronic rhinosinusitis (CRS) and airflow obstruction is still unclear. This cross-sectional study was conducted to investigate whether CRS is an independent risk factor for airflow obstruction in never-smokers without asthma. Methods: One hundred fifty-eight subjects aged ≥ 40 yr without asthma were divided into 4 groups: 22 never-smokers with CRS, 27 smokers with CRS, 69 never-smokers without CRS, and 40 smokers without CRS. Subjects with airflow obstr...
Open Access DOI:10.23937/2572-3278.1510004
Differences in Dietary Components and Oxidative Stress Markers between Cervical Cancer Patients and Matched Controls
Gabriela Gutierrez-Salmean, Mayra Acosta, Fabiola Arellano, Karolina Alvarez Altamirano, Veronica Ruiz-Manon, Guillermo M Ceballos-Reyes and Vanessa Fuchs Tarlovsky
Article Type: Review Article | First Published: July 03, 2015
Cervical cancer is a leading cause of death among women in developing countries. Diet has been suggested to play an important role in the pathophysiology of malignant tumors as an imbalance between dietary antioxidant intake and free radical production-from the inflammatory state results in oxidative stress, which may contribute to both initiation and progression of carcinogenesis. The aims of the present study were to assess the difference regarding dietary intake and oxidative stress plasmatic...
Open Access DOI:10.23937/2378-3516/1410022
Management of a Refractory Malignant Pleural Effusion in a Patient with Small Cell Lung Cancer: A Case Report
Maria M Wilczynska and Helen E Davies
Article Type: Case Report | First Published: July 20, 2015
Malignant pleural effusion (MPE) is a common presenting feature of underlying malignancy and frequently results in debilitating symptoms. In chemosensitive malignancies, such as lymphoma, small cell lung or ovarian cancers, chemotherapy is often considered the fist line treatment, however if unsuccessful, pleural intervention to achieve fluid control is required. This may include therapeutic thoracentesis, chest drain insertion, thoracoscopy, chemical pleurodesis, and use of an ambulatory indwel...
Open Access DOI:10.23937/2378-3516/1410021
Reference Values of Pulmonary Function Tests for Rural Canadians
Chandima P Karunanayake, James A Dosman, Louise Hagel, Donna C Rennie, Joshua A Lawson, Punam Pahwa and Saskatchewan Rural Health Study Group
Article Type: Original Research Article | First Published: June 22, 2015
Background: Pulmonary function tests are used routinely to evaluate patients with respiratory diseases and those who are at risk of developing respiratory diseases. Lung function prediction equations are generally developed for urban populations and whether these differ on rural population is not well studied. There is limited information on prediction equations for rural populations. Objective: The purpose of the present study was to derive prediction equations for commonly used pulmonary funct...
Open Access DOI:10.23937/2377-9004/1410050
Diagnosis and Management of Embryonal Rhabdomyosarcoma in a Woman with Prolapsing Cervical Mass
Elizabeth V. Connor and Paul A. Disilvestro
Article Type: Case Report | First Published: July 10, 2015
Background: Cervical rhabdomyosarcoma is very rare, comprising less than 1% of cervical cancers in adult women. Less than 40 cases of cervical rhabdomyosarcoma have been reported in adult women in the last 50 years. Due to the rarity of this disease, management guidelines are non-existent. Case: We present a 36-year-old woman who presented with pelvic pain and a vaginal mass. The mass was excised, and pathology confirmed poorly differentiated embryonal type rhabdomyosarcoma....