Open Access DOI:10.23937/2378-3656/1410438

Follicular Cholecystitis: A Case Report of Uncommon Morphological Spectrum of Gallbladder Lesions

Lili Ananta Saputra

Article Type: Case Report | First Published: 2023/11/20

A very uncommon subtype of chronic cholecystitis is follicular cholecystitis (FC). Hyperplastic lymphoid follicles and noticeable germinal centers are its defining features. About 2% of standard cholecystectomies involve it. A very uncommon form of chronic cholecystitis is follicular cholecystitis. At least three lymphoid follicles per cent of the gall bladder tissue and an inflammatory infiltrate that is almost entirely made up of dispersed, well-formed lymphoid follicles define it. ...

 Open Access DOI:10.23937/2469-5807/1510146

Acantholytic Squamous Cell Carcinoma Mimicking Angiosarcoma in the Oral Cavity - A Case Report and Literature Review

Rohit Parab, Laya Chadalawada, Shaina Machado and Manana Jikurashvili

Article Type: Case Report and Literature Review | First Published: 2023/11/18

Although angiosarcoma and squamous cell carcinoma represent completely different tumor entities their histologic features in some cases might be similar, especially in the head and neck region. Interestingly the clinical features might be also identical....

 Open Access DOI:10.23937/2572-4193.1510142

Multiple Myeloma Presenting as Parotid Mass Diagnosed by Fine Needle Aspiration Cytology: A Case Report

YC Spoorthy Rekha, Ramkumar Kurpad Ramachandra Rao, Kulbhushan Bali and Deepthy Das

Article Type: Case Report | First Published: 2023/11/17

Parotid region swellings are the most commonly encountered presentations in ENT OPDs, the causes of which range from inflammatory conditions to benign/malignant parotid tumors and at times can be a manifestation of an underlying systemic disease. Multiple myeloma is a rare type of blood cancer characterized by monoclonal proliferation of plasma cells and its presentation as a parotid region swelling is very rare....

 Open Access DOI:10.23937/2469-5718/1510259

The Effect of Short-Term Hyperbaric Treatment on Long COVID Symptoms: A Pilot Study

Quinn O'Malley, BA, Rami Mizher, BS and Martin J. O'Malley, MD

Article Type: Case Study | First Published: 2023/11/19

Long COVID has recently been recognized by the World Health Organization as a syndrome occurring two months after infection with Covid-19 with various physical, neurocognitive, and psychiatric symptoms that cannot be explained by another diagnosis. It is estimated that between six and twenty million patients in the United States alone are affected by this condition....

 Open Access DOI:10.23937/2643-4555/1710023

Different of Hypothalamic-Pituitary-Gonadal Axis in Male and Female

Iin Fadhilah Utami Tammasse and Fachrul Tamrin

Article Type: Review Article | First Published: November 17, 2023

Human sexual development starts early in fetal life and is completed in adulthood when the gonads have developed to their full reproductive potential. The HPG axis is a highly complex unit that influences fertility success in men and women [1]. The development, structure, and function of the HPG axis between males and females will be compared and differentiated below (Table 1)....

 Open Access DOI:10.23937/2643-4474/1710147

How Does 5-Aminolevulinic Acid Affect Histopathological Grading, Extent of Resection and Survival in High-Grade Glioma?

Vishnu A Suresh, MBChB

Article Type: Case Series | First Published: 2023/11/16

High-grade gliomas are aggressive brain tumours with a poor prognosis. The current goal of treatment is to achieve maximum safe surgical resection as this improves survival. However, the infiltrative nature of this cancer makes it difficult to delineate healthy from pathological tissue. Therefore, complete resection is rarely achieved and there is a high rate of tumour recurrence. Additionally, misdiagnosis is common and results from unrepresentative tissue sampling. This can lead to the initiat...

 Open Access DOI:10.23937/2469-567X/1510091

siRNA-Therapy for Hepatitis B Virus (HBV): A Novel Choice for HBV Treatment

Myra Sarfraz Iqbal

Article Type: Review Article | First Published: 2023/11/11

Hepatitis B virus (HBV) is a virus that may lead to chronic infection of the liver. Once infected, HBV may stay in the blood and liver for a lifetime. HBV is a non-retro virus that infects hepatocytes, with an underlying mechanism of converting its relaxed circular DNA (rcDNA), into closed circular DNA (cccDNA). The cccDNA then serves as a transcription template to transcribe viral RNAs utilizing the transcription factors meant for the host system's transcription....

 Open Access DOI:10.23937/2469-5696/1410093

Case Report and Literature Review on Patient with Sticky Platelet Syndrome and a Series of It's Complications

Lamadrid-Gámez Karina, Lopez-Zendejas Martin, Esesarte-Rodriguez Marisol, Herrera-Rojas Armando, Contreras-Cárdenas Javier, Meraz-Nieto Ivan Eduardo and Torres-García José Javier

Article Type: Case Report | First Published: 2023/11/11

We present the case of a half-blood Mexican male, 48-years-old, with a family and medical history of multiple thromboembolic events that are directly associated with the diagnosis of sticky platelet syndrome. This condition has presented diverse complications of procoagulant activity due to insufficient management therapy. Sticky platelet syndrome is an autosomal disorder that is associated with thromboembolisms....

 Open Access DOI:10.23937/2469-5696/1410092

Correlation of Manual Peripheral Blood Smear Examination with RBC Indices and Histograms Obtained from an Automated Hematological Analyzer in Anemic Patients at Jimma Medical Center, Southwest Ethiopia, 2022

Woyesa Beyene, Tilahun Yemane, Dereje Abebe, Mahder Girma, Fisum Abebe, Menberu Wubete and Edosa Tadasa

Article Type: Original Article | First Published: 2023/11/11

The manual peripheral blood smear examination is a comprehensive examination of the blood film to detect clinically significant abnormalities in leukocyte, erythrocyte, and platelet morphology. It is a time-consuming technique, but it is a more cost-effective and sensitive technique than an automated hematological analyzer. On the other hand, the automated hematology analyzer is faster, more objective, and reduces labor cost but cannot reveal the variety of abnormal cells. ...

 Open Access DOI:10.23937/2377-3634/1410174

Insulin Injection Abscesses caused by Bacteria of the Burkholderia cepacia Complex

Md Ejaz Alam, Mohammad Hayat Ahmad Bhat, Shoiab M Patto and Mohammad Afaan Bhat

Article Type: Case Report | First Published: 2023/11/04

Burkholderia cepacia complex (BCC) consists of more than 20 distinct gram-negative bacterial species. While commonly associated with cystic fibrosis (CF), BCC infections are not frequently reported in individuals with diabetes mellitus (DM). In this case report a 70-year-old female with multiple comorbidities, including Type 2 Diabetes Mellitus (DM), Chronic Kidney Disease (CKD), and Hypertension (HTN), who presented with a Burkholderia cepacia skin abscess at an insulin injection site on her an...