Open Access DOI:10.23937/2469-5718/1510262

Exercise Induced Changes in the Appearance of Circulating Microvesicles

Amit Bandyopadhyay and Nabanita Ghosh

Article Type: Review Article | First Published: 2024/02/05

Extracellular vesicles (EV) are small membrane bound vesicles which are capable of delivering biomolecules to neighbouring recipient cells or more distant cells, where they induce various signalling cascades and subsequently alter their metabolism. These EVs may include apoptotic bodies, microvesicles, and exosomes, which have emerged as important mediators of cell to cell communication in normal physiology and pathological status. ...

 Open Access DOI:10.23937/2378-3516/1410191

The Impact of Comorbidities and Obesity on the Severity of COVID-19 and Risk Factors for Mortality, A Prospective Study in Hospitalized Patients

Abdelbassat Ketfi, Rachida Yahiaoui-Sidi Said, Ghania Malki and Rama Touahri

Article Type: Research Article | First Published: 2024/02/04

The studies of the clinical and demographic characteristics of COVID-19 patients around the world have made it possible to observe a rich semiology, which implicated obesity as a factor in the severity of COVID-19 pneumonia, and can lead to intensive care or even death. Some biomarkers have been identified as risk factors for mortality. The aim of this study is to verify obesity and the risk factors for mortality of COVID-19 infection....

 Open Access DOI:10.23937/2378-3648/1410055

MTHFR Polymorphism in Congo Type 2 Diabetics: Prevalence of c.677CT and c.1298AC Mutations and Degenerative Complications

Ikia Monde VR, Boumba ALM, Alarcan H, Poaty H, Vourch P, Durebex C, Ondongo WF, Bouenizabila E, Mokondjimobe E, Andres C and Monabeka HG

Article Type: Research Article | First Published: 2024/02/03

Type 2 diabetes (T2DM) is a multifactorial disease with serious complications, particularly degenerative. Currently, several genes have been identified in its pathogenesis, including the 5,10-methylene tetrahydrofolate reductase (MTHFR) gene with an association of the c.677C>T and c.1298A>C variants. The aim of this study was first to investigate the frequency of these variants in Congolese subjects with T2DM and to compare them with healthy controls. Secondly, to establish a correlation between...

 Open Access DOI:10.23937/2474-3658/1510314

Tracking Covid-19 in England and Wales: Insights from Virus Watch - A Prospective Community Cohort Study

Wing Lam Erica Fong, Vincent Grigori Nguyen, Sarah Beale, Thomas E Byrne, Cyril Geismar, Ellen Fragaszy, Jana Kovar, Annalan M D Navaratnam, Alexei Yavlinsky, Ibrahim Abubakar, Andrew C Hayward and Robert W Aldridge

Article Type: Original Article | First Published: 2024/01/31

Virus Watch is a prospective community cohort study of COVID-19 of 28,527 households in England and Wales designed to estimate the incidence of PCR-confirmed COVID-19 in those with respiratory presentations and examine symptom profiles and transmission of COVID-19 in relation to population movement and behaviour. The Office for National Statistics (ONS) COVID-19 infection survey (CIS) was the largest regular survey of COVID-19 infections and antibodies in the UK and included 227,797 households.....

 Open Access DOI:10.23937/2572-4053.1510043

Carbon Dioxide Lingual Tonsil Reduction for Obstructive Sleep Apnea: A Feasibility Study

Andee Fontenot, BS, Stanley Yung Chuan Liu, MD, DDS and Karuna Dewan, MD, FACS

Article Type: Original Research | First Published: 2024/02/01

Obstructive sleep apnea (OSA) is characterized by frequent episodes of upper airway collapse during sleep. The lingual tonsil, when hypertrophic, can contribute to airway obstruction. The purpose of this study was to establish the utility and safety of the carbon dioxide (CO2) laser for tonsillar reduction in the management of OSA....

 Open Access DOI:10.23937/2643-4512/1710095

Personalized Therapy in Oncology: Melanoma as a Paradigm for Molecular-Targeted Treatment Approaches

Kevin B. Kim

Article Type: Review Article | First Published: 2024/01/25

Over recent decades, systemic cancer therapy has undergone significant transformations due to breakthroughs in understanding cancer biology, immunology, and genetics. Consequently, patients with advanced-stage cancers are experiencing unprecedented survival rates. Personalized cancer therapy aims to optimize clinical outcomes by tailoring drug therapies to individual patients based on their tumor genetics and/or epigenetics, thereby minimizing the toxicity associated with ineffective treatments....

 Open Access DOI:10.23937/2643-4091/1710018

Osteoblastoma of the Posterior Ilium, Complicated By Intractable Pain, Tachycardia, and Hypertension Requiring Hospital Admission after Outpatient, Percutaneous CT-Guided Biopsy

Taylor J Stone, MD, Madeline Reiker and Colin Anderson, MD

Article Type: Case Report | First Published: 2024/01/26

Osteoblastoma is a locally aggressive, osteogenic primary bone tumor primarily affecting the axial skeleton that is known to produce a local inflammatory response surrounding the tumor. This effect, known as the flare phenomenon, has been described primarily for its implications on imaging and diagnosis of osteoblastoma. The main aim of this report is to present an unusual case of osteoblastoma of the posterior ilium associated with unilateral sacroiliac joint ankylosis and chronic right-sided s...

 Open Access DOI:10.23937/2572-3235.1510119

Complete Manuscript Title: Podcasts in Interventional Radiology: Where do we Currently Stand?

Satya M N K Maripi and Konala Sunaina Reddy

Article Type: Original Research | First Published: 2024/01/26

The medium of podcasting has seen a monumental amount of growth within the past decade; this has also been in the case in the medical field. The podcast is for many a valuable tool for a range of individuals ranging from students, academics and even at an institutional level....

 Open Access DOI:10.23937/2572-3235.1510118

Magnetic Resonance Imaging Signal Intensity in the Characterization of Odontogenic Lesions: A Systematic Review

Luciana Munhoz, DDS, MS, Shunsuke Okada, DDS, PhD, Miki Hisatomi, DDS, PhD, Mariko Fujita, DDS, PhD, Yudai Shimizu, DDS, Yoshinobu Yanagi, DDS, Emiko Saito Arita, DDS, PhD and Jun-Ich Asaumi, DDS, MDSc

Article Type: Systematic Review | First Published: 2024/01/20

Databases were searched for original research studies up to August 2023. The following keywords were used: "magnetic resonance imaging" combined with "maxillofacial pathology," "oral pathology," "odontogenic tumors," "dental tissue neoplasms," and "odontogenic cysts," as well as the histologic denomination of benign odontogenic lesions according to the World Health Organization classification. No language restrictions were applied....

 Open Access DOI:10.23937/2643-4474/1710154

Recurrent Post-Traumatic Carotid-Cavernous Fistula after Endovascular Treatment

Dantas Mageste Ferreira, MD, MSc, Jéssica Aguilar da Silva, Vitor de Deus da Rocha Ribeiro Gonçalves, MD, Taianne Fiore Schumann, MD and Lano Sousa Moreira, MD

Article Type: Case Report | First Published: 2024/01/24

The High-Flow Type A Carotid-Cavernous Fistula (CCF) is the direct communication between the cavernous segment of the internal carotid artery (ICA) and the cavernous sinus. Its most frequent etiology is trauma, more commonly occurring in males. Clinically, it is characterized by the Dandy triad of hyperemia, exophthalmos, and ocular bruit. The described case involves a male patient who presented with a classic high-flow CCF, underwent coil embolization, showed a satisfactory response in the firs...