Open Access DOI:10.23937/2469-584X/1510063
Visceral Artery Pseudoaneurysm Rupture after Pancreaticoduodenectomy
Tolga Aliyazicioglu, Senol Carilli, Izzet Rozanes and Ali Sami Emre
Article Type: Case Report | First Published: December 31, 2018
Although mortality after pancreaticoduodenectomy (PD) in high volume centers is less than 5%, morbidity is still as high as 30 - 50%. Hemorrhage from ruptured pseudoaneurysm is a rapidly progressing and potentially fatal complication after PD.Visceral pseudoaneurysm after pancreatic surgery is well known by surgeons. Postpancreatectomy hemorrhage is a life threatening entity, and must be managed urgently. Here we report two cases, late massive bleeding after pancreaticoduodenectomy. First case i...
Open Access DOI:10.23937/2378-346X/1410107
Refraction Data Survey, Ensemble & Time Series Statistics during Adolescence
Peter R Greene, PhD, Otis S Brown, EE and Ronald M Berger, OD
Article Type: Original Research Article | First Published: April 20, 2019
The objective of this report is to quantify left eye to right eye refractive state differentials resulting from the accumulation of naturally occurring random fluctuations. Clinical SER data from adolescent emmetropic human subjects are measured and analyzed in terms of ensemble and time-series and fluctuations of the left eye , right eye , and left-right differential measurement, N = 20 subj. Results include random fluctuations for left and right eyes of human subjects age 11 to 23 years. Ensem...
Open Access DOI:10.23937/2572-4193.1510058
Congenital Cholesteatoma of Petrous Apex: A Case Report
Muhd Faiz Bin Zulkifli and Lokman Bin Saim
Article Type: Case Report | First Published: April 20, 2019
A 23-year-old female presented with progressive left sided facial asymmetry for 4 years and progressive hearing loss in the left ear for 2 years. She had normal left tympanic membrane and complete left lower motor neuron facial nerve palsy. High resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) temporal bone showed extensive bony destruction, petrous apex and soft tissue lesion. Patient then proceed with transmastoid translabyrinthine approach. Diagnosis of cholesteatoma...
Open Access DOI:10.23937/2469-5807/1510087
Cellular Desmoplastic or Anaplastic Supratentorial Ependymoma with Neuronal Differentiation in Probable Associated to RELA Fusion? Case Report
Martha Lilia Tena-Suck, Armando Ruiz-Trevino, Laura Chavez-Macias, Carlos Penafiel-Salgado and Carlos Sanchez-Garibay
Article Type: Case Report | First Published: April 20, 2019
Cellular Ependymoma is a term losing in the new WHO 2016 criteria, actually are classified as classical or anaplastic or associated to RELA fusion. We presented a rare case report of classical cellular ependymoma in supratentorial location, which presented a neuronal differentiation and desmoplasia in a young man of 29-yr-old, Immunohistochemistry tumor cells expressed Neu-N, Synaptophysin, SNE, α-synuclein, beta tubulin, ubiquitin, neurofilament, D2DR, and GFAP and vimentin. This rare tumor is...
Open Access DOI:10.23937/2378-3419/1410111
Importance of Time to Chemotherapy Initiation in Small Cell Lung Cancer
Gregory J Kubicek, Rachel Koehler, Matthew J Rossi, Christian Squillante, Alexander Hageboutros, Melvin Pratter, Stephen Akers and Polina Khrizman
Article Type: Original Article | First Published: April 20, 2019
Small cell lung cancer (SCLC) is an aggressive malignancy with a short median survival time. Because of the rapid growth rate there may be an advantage to emergently beginning chemotherapy as soon as SCLC diagnosis is made. All SCLC patients evaluated at Cooper University Hospital from January 2011 to September 2014 were reviewed. Multiple clinical factors were analyzed including timing between diagnosis and start of chemotherapy....
Open Access DOI:10.23937/2378-3656/1410264
Chronic Eosinophilic Pneumonia: A Pediatric Case
Irene Rutigliano, MD, Sara Gorgoglione, MD, Anna Pacilio, MD, Carmela De Meco, MD and Michele Carmine Sacco, MD
Article Type: Case Report | First Published: April 20, 2019
A 12-year-old nonsmoking asthmatic girl was admitted for general malaise and dry fatiguing cough. Diagnostic course reveled marked hypereosinophilia and chest radiography indicated multifocal and circumscribed bilateral pulmonary areas of consolidation. Bronchoscopy excluded the presence of neoplastic cells but marked hypereosinophilia was found in bronchoalveolar lavage. The increased number of eosinophils in blood and in bronchoalveolar lavage, the radiological findings were suggestive of Chro...
Open Access DOI:10.23937/2469-5734/1510086
Classification of the Methods of Local Anesthesia and Special Features of Vascular-Diffuse Injection
Petrikas AZ, Medvedev DV, Yakupova LA, Efimova OE, Chestnyh EV, Kulikova KV and Sazonova KA
Article Type: Review Article | First Published: April 19, 2019
The main feature of modern injection methods of dental anesthesia is in the local venous spreading of the anesthetic in the near-toothed spongy substance of the bone and dental pulp. The vascular mechanism is controlled by the epinephrine anesthetic solution and patient vegetal system. Spongy dental anesthesia is universal, highly effective, relatively safe, easy to implement and increasingly widespread. Classification proposed by us is the division of injection methods of anesthesia into tradit...
Open Access DOI:10.23937/iaos-2017/1710007
Open Fractures Treated in a Regional Trauma Centre in Nigeria: Presentation and Outcome - A Prospective Observational Study
Ibeanusi SEB and Obalum DC
Article Type: An Observational Study | First Published: April 19, 2019
Open fractures present a significant challenge to the patient and his family and the managing surgeons. Open fracture often results from high energy injuries such as road traffic crashes, gunshot injuries, falls from heights and high-speed sports. Open fractures are associated with life-threatening and limb threatening injuries and are often associated with complications such as infection, malunion, and non-union. Controversies abound in the pattern of presentation, management, and outcome of op...
Open Access DOI:10.23937/2469-5823/1510121
Iron Deficiency Anemia in Infants of Hatta Suburb-UAE
Dileep Kumar, Zahid Nabi Qureshi and Mouza Saif Albadwawi
Article Type: Original Article | First Published: April 19, 2019
Worldwide burden of ID estimated to be 43% globally in 2011 and about 70% in Central and West Africa and 7-9% of USA children ages 1-3 years have iron deficiency (ID). Countries in high caloric nutrition switch have a high prevalence of overweight and obesity, a moderate prevalence of undernutrition and micronutrient deficiencies. Infants and children must obtain 30% of their daily iron from their diet to provide the necessary iron for new muscle cells and RBCs....
Open Access DOI:10.23937/2378-3419/1410110
The Use of Carboranes in Cancer Drug Development
Emilia O Zargham, Christian A Mason and Mark W Lee Jr
Article Type: Review Article | First Published: April 18, 2019
Over the past decade, there has been a rising interest in the use of carboranes as a potential pharmacophoric moiety in the development of new drugs for the treatment of various types of cancer. The unique physical and chemical properties of carboranes make their use attractive in drug development. In several instances, the inclusion of carboranes into a drug structure has increased the agent's binding affinity, potency, or bioavailability. The purpose of this review is to highlight applications...