High Anti-Acid Omeprazole Lightweight Capsule for Gastro-Enteric System Acid-Related Disorders Treatment
Longjian Geng, Lidong Han, Lulu Huang, Ziheng Wu, Zhenghong Wu and Xiaole Qi
Article Type: Research Article | First Published: September 26, 2019
Utilization of diverse anti-acid materials is necessary for the preparation of compound omeprazole capsules. However, to gain the satisfied anti-acid effect, use of large amount of anti-acids is always difficult to swallow. This study aimed to develop a lightweight compound omeprazole capsule which could achieve immediately drug releasing with high anti-acid ability in stomach. In this study, we successfully prepared OMZ-CD, which were characterized and compared with micronized OMZ. An improved ...
Efficacy and Safety of Direct Acting Antivirals (DAAs) in an Urban Clinical Setting
Olga M. Klibanov, Delina Meskel, Chris Gillette and Tagbo J Ekwonu
Article Type: Research Article | First Published: June 21, 2019
This retrospective cohort included patients who initiated on DAAs between May 2014 and May 2018. The primary endpoint was SVR12. Descriptive statistics were used to analyze the results. Bivariate associations between patients achieving treatment success and demographic and clinical variables were conducted using chi-square, Fisher's exact test, and independent samples t-test with a two-sided alpha value of 0.05....
Inflammatory Bowel Diseases (IBD) - Associated Spondyloarthropathy in the Biologic Era: A Case Series
Cristina Tocia, MD, Luana Alexandrescu, MD, Victoria Cristina Șuța, MD and Eugen Dumitru, MD
Article Type: Case Series | First Published: April 29, 2019
Articular manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases and are classified into axial spondyloarthritis (SpA) and peripheral SpA. EIM may occur before or after IBD diagnosis, being the proof that IBD is not only limited to gut. Here we present a case series of three patients with Crohn's disease and extraintestinal manifestations admitted to our hospital. Patients had in common young age, Crohn's disease with moderate or severe clinic and endosc...
Migrated Esophageal Stent Endoscopic Extraction through Gastrostomy Site in a Patient with Severe Esophageal Stricture
Claire M Shin and Steven B Clayton
Article Type: Case Report | First Published: April 18, 2019
A 36-year-old woman with a history of benign refractory esophageal stricture from gastroesophageal reflux disease was treated with anesophageal stent and a gastrostomy tube 2 months prior to presenting with acute dysphagia and odynophagia. Esophagram and upper endoscopy revealed esophageal stent migration into the stomach and a pinpoint stricture of the distal third of the esophagus, which made retrograde extraction unfeasible. The stent was successfully extracted through the pre-existing gastro...