International Journal of

Medical Nano ResearchISSN: 2378-3664

Early Online

 Open Access DOI:10.23937/2378-3664.1410040

En Bloc Staining with Uranyl Acetate Zero (UA-Zero) for Transmission Electron Microscopy

Santhana Raj L, Fauzah Abd Ghani, Jing Siew Ting, Intan Shameha Abdul Razak and Nur Afrina Muhamad Hendri

Article Type: Electron Microscopy | First Published: 2023/12/15

Uranyl acetate (UA) is one of the heavy metals used to stain tissue in sample preparation for transmission electron microscopy (TEM). It gives excellent contrast to ultrastructure morphology. Unfortunately, UA is very toxic and has proven to be a carcinogen and radioactive reagent. Meanwhile, UA-Zero is a UA replacement with improved staining property has shown better for staining due to its safety profile and environmental-friendly properties....

 Open Access DOI:10.23937/2378-3664.1410039

Possible Effect of Nano Characterization of COVID-19 on Infection and Causing Disease

Wang Shenguo

Article Type: Original Article | First Published: February 23, 2023

In this article, based on analysis of chemical composition and morphology structure of the New Coronavirus Disease-19 (COVID-19), that the COVID-19 belongs a kind protein nanoparticle virus with spherical complex structure has been explained. So, the COVID-19 possesses characteristics of ultra-small size, large specific surface, both hydrophilicity and lipophilicity, that just as all of the nanoparticles. It leads to the COVID-19 producing fast spread speed, large spread range and strong infecti...

 Open Access DOI:10.23937/2378-3664.1410038

Study of Mesenchymal Stem Cell in Combination with Self-Assembled Functional Nanopeptide Gel to Promote Angiogenesis

Zhanao Liu, Ailing Tian, Xin Yi, Nianfeng Sun and Yong Di

Article Type: Research Article | First Published: January 15, 2023

To investigate the transplantation of a functionalized self-assembling nanopeptide hydrogel loaded with adipose-derived mesenchymal stem cells (AD-MSCs) into a rabbit hindlimb ischemia model and to evaluate its effect in promoting vascular regeneration in ischemic tissues. Functionalized self-assembling nanopeptide hydrogels were synthesized, and the physical and chemical properties of the hydrogels were observed by electron microscopy. Primary AD-MSCs were isolated, cultured, immunophenotyped, ...

 Open Access DOI:10.23937/2378-3664.1410037

Therapeutic Application of Nanomaterials in the Management of Health Care: ‘An Updated Review’

Pooja Mishra, Irum, Akhtar Hussain and Abu Baker

Article Type: Review Article | First Published: November 14, 2021

The provision of healthcare, which is a fundamental human right, has frequently been the subject of cutting-edge technology development. The availability of high-quality, timely, acceptable, and reasonably priced healthcare has greatly benefited from technological advancement. A new generation of nanostructures has emerged as a result of developments in nanoscience. They each have a distinct set of characteristics that contribute to their amazing uses....

 Open Access DOI:10.23937/2378-3664.1410036

Encapsulation of Alendronate in Chitosan based Polymeric Nanoparticles for Effective Management of Osteoporosis - Development to Release Kinetic Study

Sandhya Pathak, Satyendra Kumar Tripathi, Chandni Pachouri and Archna Pandey

Article Type: Research Article | First Published: January 31, 2022

Osteoporosis means "Porous bone” is a disease characterized by progressive bone thinning. The deterioration of bone tissue can lead to bone fragility and fracture, especially of the hip, spine, shoulder and wrist. Osteoporosis is characterized by decreasing bone mineral density (BMD). Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis in the US and many other countries including India. Alendronate (Aln) is a widely used anti-osteoporosis drug, exhibits str...

Volume 9
Issue 1