Open Access DOI:10.23937/2378-3656/1410472
When Stones Speak: E. Coli Sepsis Leading to the Diagnosis of Hyperparathyroidism
Mandeep Kaur
Article Type: Clinical Case | Indexed Archive: Volume 12
We describe a 64-year-old woman with hypertension and gastroesophageal reflux disease who presented with fever, chills, and abdominal discomfort. Evaluation revealed an obstructive right-sided ureteral stone with sepsis due to Escherichia coli bacteremia. Urological intervention with cystoscopy and ureteral stent placement was performed. The case was further complicated by hypercalcemia secondary to primary hyperparathyroidism, likely contributing to recurrent nephrolithiasis, and sepsis-associa...
Open Access DOI:10.23937/2378-3656/1410471
Incidental Finding of Primary Ovarian Malignancy at Cesarean Section: A Case Report
Emily Ensley, Danielle Pischullaa, Ashley Barra, Scarlett Bloodworth, Katelyn Jo Light and Hector Chapa
Article Type: Case Report | Indexed Archive: Volume 12
The prognosis of cancer is highly dependent on its stage at diagnosis, with early diagnosis strongly correlating with better treatment outcomes. The incidence of discovering cancer during pregnancy has steadily increased over the years, with 1/2000 cases reported in the 1960s to 1/1000 cases currently reported.1 However, these diagnoses are primarily driven by patients experiencing symptoms that prompt their healthcare team to investigate the possibility of cancer. Incidental findings of cancer ...
Open Access DOI:10.23937/2378-3656/1410469
Thalassemia in the 21st Century: Challenges, and Solutions, a Review Article
Suad M. Jatal, Sawsan J. Harfouch and Rim M. Harfouch
Article Type: Case Report | Indexed Archive: Volume 12
Thalassemia is among the most common inherited hemoglobin disorders worldwide, caused by mutations that impair the production of alpha or beta globin chains, resulting in chronic hemolytic anemia and significant morbidity. Advances in supportive care, such as regular blood transfusions and iron chelation therapy, have dramatically improved survival, yet iron overload, cardiac failure, endocrine dysfunction, and infections remain major complications. This review summarizes the current understandi...
Open Access DOI:10.23937/2378-3656/1410466
Successful Mesenchymal Stem Cell Therapy in A Patient with Ciprofloxacin Sensitivity
Ramazan Ersoy, Ayberk Akat and Erdal Karaoz
Article Type: Case Report | Indexed Archive: Volume 12
Fluoroquinolones are frequently prescribed due to their wide range of antibacterial effects, ease of administration, and widespread availability. However, they are also the second most frequent antibiotics associated with drug allergies. Although it is effectiveness, the potential for causing severe allergic reactions may restrict the available treatment options. Mesenchymal stem cells have the potential to be used as therapeutic agents because of their ability to modulate the immune system and ...
Open Access DOI:10.23937/2378-3656/1410465
Antibiotic Stewardship to Combat Antimicrobial Resistance Menace: Present Updates, Challenges, and Future Directions
Mohan Bilikallahalli Sannathimmappa
Article Type: Review Article | Indexed Archive: Volume 12
The increasing trend in resistance to antimicrobial agents is a major threat to the management of infectious diseases. If nothing is done, we may return to a pre-antibiotic era where a minor infection is potentially fatal. Therefore, it is important to use antibiotics judiciously to prevent serious public health threats. To this day, many policies and guidelines have been laid out to define the ideal selection, the correct dosing, and the appropriate duration of antibiotic therapy....
