Clinical Medical

Reviews and Case ReportsISSN: 2378-3656

Early Online

 Open Access DOI:10.23937/2378-3656/1410258

An Unexpected Lower Urinary Tract Symptom of Multiple Sclerosis: Valsalva Induced Urge Incontinence

Murat Akgul, MD, CenkYazıici, MD, NildaTurgut, MD, Arzu Malak and Mehmet Fatih Sahin, MD

Article Type: CASE REPORT | First Published: February 28, 2019

A 46-years-old male with the history of multiple sclerosis applied to urology outpatient clinic with frequency, urgency, incontinence, and nocturia. Urodynamic evaluation presented Valsalva-induced urge incontinence, which was an unusual finding for an MS patient. Here we present an MS patient with the urodynamic finding of Valsalva-induced urge incontinence. Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system, mostly affecting the people between ...

 Open Access DOI:10.23937/2378-3656/1410257

Management of Non-Classic Congenital Adrenal Hyperplasia in Pregnant Woman - Non-Referral Center Experience- Case Report

Zoran Gluvic, Milena Lackovic, Vladimir Samardzic, Bojan Mitrovic, Violeta Mladenovic, Milan Obradovic, Danimir Jevremovic and Esma R Isenovic

Article Type: Case Report | First Published: February 22, 2019

Congenital adrenal hyperplasia (CAH) is a rare autosomal recessive disorder with mutations in genes involved in cortisol and aldosterone production. Based on overall 21-OHase activity, CAH is divided into classic (C-CAH) and non-classic (NC-CAH). Females who suffered from NC-CAH have had increased infertility rates and higher miscarriage susceptibility. The treatment of CAH in pregnancy is still debatable. We present 22 years old pregnant female (seventh week of gestation), who is currently unde...

 Open Access DOI:10.23937/2378-3656/1410256

High Focused Ultrasound in a Case of Previously Untreated Breast Cancer

Hans-Christian Kolberg, MD, PhD and Cornelia Kolberg-Liedtke, MD, PhD

Article Type: Case Report | First Published: February 20, 2019

High focused ultrasound is a non-invasive treatment used for destroying benign and potentially also malignant tumors. Recent data have suggested that the generation of large volumes of tumor debris by high focused ultrasound may initiate an adaptive antitumor immune response by the release of tumor antigens and damage associated molecular patterns. The patient, a 48-year-old woman who was diagnosed with hormone receptor positive HER2 negative breast cancer 17 months before presentation had repea...

 Open Access DOI:10.23937/2378-3656/1410255

Soluble ST2 - A Potential Biomarker of Rheumatic Heart Disease

Ramona Januska, MD, Alexander von Meyer, MD, Martin Fleck, MD and Andreas Luchner, MD

Article Type: Case Report | First Published: February 18, 2019

Soluble ST2 might be a sensitive marker of rheumatic (peri-)carditis before and during antirheumatic treatment. We describe a case of rheumatic heart disease with pericarditis and mild left ventricular dysfunction which was successfully treated by immunosuppression. An interesting pattern of activation of the cardiac marker ST2 was observed at detection and during treatment. It suggests ST2 as biomarker for diagnosis and monitoring of disease activity in rheumatic heart disease. Rheumatic disord...

 Open Access DOI:10.23937/2378-3656/1410254

Intensification of Weight Loss with the Ketogenic Diet during the Management of a Super Obese: Case Study

Jamile Nobrega Zeraik Abdalla, Livia Lugarinho Correa, Priscilla Gil, Silvia de Freitas, Ignacio Sajoux, German Guzman and Walmir Coutinho

Article Type: Case Report | First Published: January 12, 2019

Obesity is a chronic disease referred to as a world epidemic. Superobesus management is challenging and requires multidisciplinary follow-up. In this case report, the patient had an initial body mass index (BMI) of 110 kg/m² associated with comorbidities such as type 2 diabetes (T2DM). Initial clinical management was performed with changes in lifestyle, through hypocaloric and ketogenic diet, associated with several antiobesity drugs and the introduction of light physical activity. After a tota...

 Open Access DOI:10.23937/2378-3656/1410253

Juvenile Huntington' Disease: A Case of Paternal Transmission with an Uncommon CAG Expansion

Luciana de Andrade Agostinho, Luiz Felipe Vasconcellos, Victor Calil da Silveira, Thays Apolinario, Michele da Silva Gonçalves, Mariana Spitz and Carmen Lucia Antao Paiva

Article Type: Brief Report | First Published: January 04, 2019

We report a patient with paternally inherited JHD caused by a large (74 CAG) expansion. The patient was prescribed olanzapine 2.5 mg q.d., oxcarbazepine 300 mg bid and underwent botulinum toxin treatment, with partial improvement of aggressiveness and chorea and partial resolution of torticollis. The MRI revealed bilateral caudate and putamen atrophy. JHD is rarer than adulthood HD, with an average prevalence rate of 5%. UHDRS has limited efficacy in evaluating JHD patients independence and func...

 Open Access DOI:10.23937/2378-3656/1410252

Effects of Hematocrit on Cardiac Parameters for Shock Patients

Rabindra Nath Das and Youngjo Lee

Article Type: Short Research Article | First Published: January 04, 2019

The hematocrit known as erythrocyte volume fraction (EVF) or packed cell volume (PCV), is the volume percentage of red blood cells in blood. The present report examines the association between hematocrit (HCT) and anyone of seven cardiac parameters such as shock type (SHOCKT), heart rate (HR), mean arterial pressure (MAP), cardiac index (CI), systolic blood pressure (SBP), mean central venous pressure (MCVP), diastolic blood pressure (DBP) for shock patients. It is reported herein that that mean...

 Open Access DOI:10.23937/2378-3656/1410251

A Case Report of an Intestinal Helminth Infection of Human Hymenolepiasis in Rural Gambia

Usman N Ikumapayi, Chilel Sanyang and Dora IA Pereira

Article Type: Case Report | First Published: January 04, 2019

Hymenolepis nana, also called dwarf tapeworm infection, is an intestinal helminth not previously reported in The Gambia and only very rarely reported in West Africa. We report a case of H. nana infection in a 29-month old child living in a rural community of the north bank of the Upper River Region (URR) in The Gambia. The child presented with mild iron deficiency anaemia and granulocytosis but was otherwise mostly asymptomatic despite the moderate-intensity of infection....

 Open Access DOI:10.23937/2378-3656/1410250

A Case of Secondary Aortoduodenal Fistula Diagnosed by Esophagogastroduodenoscopy

Kyosuke Goda, Masanori Kawaguchi and Akiko Shiotani

Article Type: Case Report | First Published: January 03, 2019

A 64-year-old man underwent vascular graft surgery for an abdominal aortic aneurysm one year previously. Using esophagogastroduodenoscopy (EGD), he was definitively diagnosed as having an aortoenteric fistula (AEF) and underwent an urgent surgical procedure for treatment. Generally, the prognosis in cases of AEF after vascular graft operation remains poor, and the survival rate in cases of AEF that require surgery is low. We report this case of AEF because EGD played a significant role in its ea...

 Open Access DOI:10.23937/2378-3656/1410249

Case Report and Review of Literature: An Overlap Syndrome of Autoimmune Hepatitis and Systemic Lupus Erythematous

Charelle Salem, Elie Makhoul and Tony El Murr

Article Type: Case Report | First Published: January 03, 2019

Autoimmune Hepatitis (AIH) is a chronic necroinflammatory liver disease of unknown etiology associated with circulating autoantibodies and high serum globulin level. Systemic lupus erythematous (SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complex, affecting multiple organs including the liver, kidney, and CNS. AIH has been considered to occur infrequently in SLE. We report a 42-year-old female patient with an overlap syndro...

Volume 6
Issue 1