Open Access DOI:10.23937/2643-4563/1710054
Rare Breast Cancer: Primary Melanoma of Breast Parenchyma
Mohamed Moneer Abulfotooh Alsayed, MSc, MRCS, Amal Yousif Saleh Abdullah, Ashraf Ahmed Abdeltawab Ibrahim, Ghaidaa Naser Abdul Razak, Sana Tabish and Rana Al Abdulghani
Article Type: Case Report | First Published: 2023/10/14
Melanoma is a highly aggressive cancer that can be cutaneous (most common) or mucosal, affecting the skin or mucous membranes at any organ in the body. It can also be found in the eye (uveal). Breast melanoma is rare, and it can manifest in one of three forms: 1) Metastatic secondary to primary melanoma at another site, 2) Primary cutaneous melanoma arising at the breast skin, or 3) Primary non-cutaneous melanoma arising in the breast parenchyma itself. ...
Open Access DOI:10.23937/2643-4563/1710053
Liver Metastasis: Current Concepts in Management and Future Perspectives
Aditya Sharma, Ram Niwas Meena, Rahul Khanna and Seema Khanna
Article Type: Review Article | First Published: 2023/08/20
Liver metastasis can be defined as the seeding of a malignant tumour from other organs affected by cancer. About half of the patients with colorectal cancer develop liver metastases during the progressive course of the disease. Surgery is the only curative treatment for patients with metastatic liver disease, and the five-year survival rate after resection of all detectable liver metastases can be as high as 40%. Unfortunately, only 25% of patients with liver metastases are candidates for liver ...
Open Access DOI:10.23937/2643-4563/1710052
Dose Variation Profiles of Small Fields with a 10 MV Photon Beam
Caio Fernando Teixeira Portela and Arnaldo Prata Mourão
Article Type: Original Article | First Published: 2023/05/20
Radiotherapy is a treatment of carcinogenic tumors using ionising radiation and the improvement of radiotherapy techniques has been conducted to protection of healthy tissues. Recent implementations have employed static fields with small dimensions. The interests for this work were small fields, used in modern techniques such as Stereotactic Radiation Therapy (SRS) and Intensity Modulated Radiation Therapy (IMRT). These fields have special characteristics that refer to the non-establishment of t...
Open Access DOI:10.23937/2643-4563/1710032
Nivolumab Induced Acute Pancreatitis and Hyperbilirubinemia
Unnati Bhatia, MD, Suryansh Bajaj, MD, Darshan Gandhi, MD, Divyansh Bajaj, MD
Article Type: Case Report | First Published: December 05, 2021
Immune checkpoint inhibitors (ICIs) are a novel treatment modality that is quickly becoming the standard of care for the management of a multitude of neoplasms. While immunomodulation is a promising approach, it also carries a risk of immune-related adverse effects (irAEs). Nivolumab is an FDA-approved anti-programmed death-1 (anti-PD-1) checkpoint inhibitor. Nivolumab-induced, immune-related pancreatitis, and hyperbilirubinemia are rare but clinically significant examples of irAEs. Early recogn...
Open Access DOI:10.23937/2643-4563/1710031
Incidentally Found Thyroid Metastases in Head and Neck Squamous Cell Carcinoma - How to Manage It?
Gama R, Oliveira P, Teixeira M, Castro F and Condé A
Article Type: Original Article | First Published: September 10, 2021
The authors aim to review the available literature regarding incidentally found thyroid carcinoma during lymph node dissection for primary head and neck squamous cell carcinoma (SCC), in order to potentially support clinical decision about management of this unexpected entity. 2 clinical cases are described and a systematic review of the relevant literature on the subject is performed based on Pubmed® database. We reviewed a total of 102 cases. The primary SCCs sites were larynx, oral cavity, a...
