Review Timeline | CrossMark Policy | ClinMed Features
logo
International Journal of

Brain Disorders and TreatmentISSN: 2469-5866

Current Issue

 Open Access DOI:10.23937/2469-5866/1410045

Post-Traumatic Stress Disorder: Sleep Disturbances and Biomarkers

Jason Armstrong, Mary Jo Kurth, Joanne Watt, Peter Fitzgerald and Mark W. Ruddock

Article Type: Review Article | Indexed Archive: Volume 9

The neurobiological features of Post-Traumatic Stress Disorder (PTSD), a debilitating psychiatric condition triggered by exposure to traumatic events, are associated with enigmatic pathological mechanisms which are becoming clearer as the library of associated literature increases. This article considers the clinical features of PTSD, the neural circuitry at work, and some of the genetic and epigenetic factors contributing to PTSD risk. ...

 Open Access DOI:10.23937/2469-5866/1410040

Case Series: Chronic Pediatric Ischemic Stroke in Childs Successfully Treated with IAHF Procedure

Terawan A Putranto, Taruna Ikrar, Ardianto Pramono, Samuel Tandionugroho, Rachmanto HSA

Article Type: Case Report | Indexed Archive: Volume 7

Occlusion or rupture of cerebral blood vessel can cause a stroke. It can occur either on a child and adult even it unusual in children. Stroke in pediatric population is rare but it carries often long-term disability and mortality. We present two cases of pediatric stroke with metabolic disease as underlying disease. One of them admitted with weakness and clumsiness persisted of right hand and leg. The other one admitted with weakness in the left hand and leg. Both showed motor improvement and p...

 Open Access DOI:10.23937/2469-5866/1410039

Adults with Neurodevelopmental Disorders Continue to Receive Lower Quality Health Services: A Call for “Quality Improvement” Programs

Luz Fernandez, MD, Jon Becker, MD and Philip May, MD

Article Type: Commentary | Indexed Archive: Volume 7

Neurodevelopmental Disorders (also known as Intellectual and Developmental Disabilities-ID/DD) are associated with multiple-complex-health-conditions that, in contrast to children, are often not evaluated and/or managed properly as adults. The specialty of Developmental and Behavioral Pediatrics exists for children with ID/DD, but there is no equivalent specialty for the adults. Since Family Medicine has taken the lead in providing primary care for adults with ID/DD, we propose that Family Medic...

 Open Access DOI:10.23937/2469-5866/1410038

Long-Term Survival (23 Years) in a 26-Year-old Male after Antineoplaston Therapy for a Progressive, Diffuse Intrinsic Pontine Glioma: A Case Report

Stanislaw R. Burzynski, Gregory S. Burzynski, Tomasz Janicki and Samuel Beenken

Article Type: Case Report | Indexed Archive: Volume 7

Individuals suffering from diffuse intrinsic pontine glioma (DIPG) face a dismal prognosis with a median overall survival of approximately 11 months, and a 2-year survival rate of 10%. Long-term survival is very rare. To date, radiotherapy remains the standard of care at diagnosis, but offers a survival benefit of approximately 3 months. Chemotherapy has not shown to be effective. There is no Standard of Care for progressive DIPG after radiation therapy (RT). The purpose of this case report is t...

 Open Access DOI:10.23937/2469-5866/1410037

Effective Treatment of Dystonia with Deep Brain Stimulation and Tetrabenazine in Pantothenate Kinase-Associated Neurodegeneration: A Case Report

Isabel C Londoño, Luz Miriam Leiva and Hamilton Delgado Argote

Article Type: Case Report | Indexed Archive: Volume 7

Pantothenate kinase-associated neurodegeneration is a rare disease, difficult to diagnose and treat. It is characterized by a progressive extrapyramidal dysfunction with typical onset in the first two decades of life and by a set of clinical manifestations such as speech disturbance, focal or generalized dystonia, pigmentary retinopathy associated with mild cognitive impairment. 10-year-old male patient, who until this age was managed under a diagnosis of cerebral palsy sequelae with poor respon...

Volume 7
Issue 1