Glycosphopeptical and Specific Immunotherapy Effect in Allergic Rhinitis
Becerril-Bautista Baltazar, Jimenez-Uscanga Ruben Dario, Vargas-Camano Maria Eugenia, Cesar Daniel Alonso-Bello, Lozano-Patino Fernando, Sanchez-Leon Maria del Carmen, Juarez-Santiago Lucero and Maria Isabel Castrejon-Vazquez
Article Type: Original Article | First Published: October 17, 2018
Allergic rhinitis (AR) is an inflammatory disease mediated by immunoglobulin E (IgE) following exposure of the nasal mucosa to an allergen. Glycophosphopeptical (GFP) is a molecule composed of polysaccharides of fungal origin and proteins of vegetal origin, adsorbed in an inorganic phosphate-sulfate-calcium matrix, stimulates the innate immunity, during infectious processes. The objective of the study was to analyze the clinical response of specific immunotherapy (SIT) and the use of GFP in pati...
Thrombocytopenia in a Patient with Severe Combined Immune Deficiency: An Unusual Cause
Farrukh Sheikh, Safiah Sumayli, Hasan Hakami, Agha M Rehan Khaliq, Sulaiman Al Gazlan, Hasan Alrayes, Ghuzayel Al-Dawsari, Riad El Fakih and Rand Arnaout
Article Type: Short Communication | First Published: September 22, 2018
We report the first case of severe intractable thrombocytopenia in a patient with adenosine deaminase deficiency, Severe Combined Immune Deficiency (SCID), necessitating hematopoietic stem cell transplant. This patient developed severe thrombocytopenia from polyethylene glycol adenosine deaminase and needed a hematopoietic stem cell transplant as an adolescent. She did well afterwards, overall. Although rare, thrombocytopenia can result from polyethylene glycol adenosine deaminase. Hematopoietic...
Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome
Katharine J Foster, Jonathan Rodrigues, Julia Lee, Sara Powell, Roua Azmeh and Alan P Knutsen
Article Type: Research Article | First Published: August 18, 2018
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome (PFAPA) is characterized by periodic cyclical fever, cervical adenopathy, pharyngitis, and aphthous stomatitis. Administration of oral corticosteroids at the onset of fever is the current initial treatment. Tonsillectomy resolves PFAPA symptoms in 50-100% of patients....
A Case of SLE that Healed Completely after Ten Intradermal Injections with a Non-Specific Antigen Preparation
Article Type: Case Report | First Published: August 13, 2018
According to the traditional concept of the contemporary Immunology, neither autoimmune diseases nor allergic diseases can be cured completely. Nevertheless, a fortunate coincidence led the author to discover a novel concept that eliminations of the causes of these diseases are possible. In other words, combinations of pathogenic antibodies with responsible cells, namely, cytolytic T lymphocytes in cases of autoimmune diseases and mast cells in cases of allergic diseases, can be decomposed by re...
Importance of Allergic Hypersensitivity to Medications
Angel San Miguel-RodrIguez, Alicia Armentia, Sara MartIn-Armentia, Blanca MartIn-Armentia, Mª Carmen Lozano Estevan and Irene Iglesias Peinado
Article Type: Original Article | First Published: August 08, 2018
Allergic drug reactions (ADR) are the third most common reason for consultation in allergy services. Epidemiological data are imprecise. Globally, ADR affect 10-20% of hospitalized patients and up to 7% of outpatients. However, this might be an underestimate due to underreporting, or an overestimate due to unexplained reactions often being classified as "allergic". ...
Vitamin D Levels in Patients with Anaphylaxis with or without Asthma Compared to the General Population
Farrukh Sheikh, Agha M Rehan Khaliq, Qasim A Sheikh, Abdul Hadi Al Qahtani, Samia Al Hashim, Rand Arnaout and Rashid Amin
Article Type: Research Article | First Published: August 06, 2018
Vitamin D has immunomodulatory properties. Most of the evidence points towards a causal association between low vitamin D levels and the development of asthma and allergy but the results are not conclusive. We studied the vitamin D levels of patients with anaphylaxis and compared them to previously published vitamin D levels in the Saudi population....
Positive Effects of Acupuncture on Atopic Dermatitis
Rezan Akpinar and Saliha Karatay
Article Type: Literature Review | First Published: July 06, 2018
Atopic dermatitis, or allergic eczema, is a chronic inflammatory skin condition which is noncontagious and leads to itchy, dry skin lesions that can damage the intact skin barrier. Although the etiology is not known, it is widely believed that family history and allergies play a role. The incidence of atopic dermatitis is usually higher in early childhood, while other allergic conditions can develop later in life, such as allergic rhinitis and asthma. Atopic dermatitis is typically treated throu...