Obesity is considered an increasing problem in the worldwide population, reaching epidemic proportions of about 400 million obese people in the world. The accumulation of adipose tissue leads to chronic oxidative stress, since its excess is associated with the development of inflammation, increasing the probability of developing comorbidities due to weight gain. This research aimed to evaluate the changes in inflammatory and antioxidants biomarkers after bariatric surgery in patients with morbid obesity. The study was executed with a population of 63 people with morbid obesity, composed of 77% of women and 23% of men, analyzing their food consumption, antioxidant level, oxidative stress, anthropometric and biochemical data. It was observed that after 6 months of surgical procedure, in addition to weight loss, there was a significant improvement in antioxidant biomarkers and oxidative stress.