Bartonellosis or Cat Scratch Disease (CSD) is defined as an infectious, benign illness that in most cases results from the scratching, licking or biting of animals carrying the bacterium Bartonella henselae. This study aims at describing the epidemiological profile of serologically reactive samples between the years 2011 and December 2017 in Brazil. Official data from the requests for diagnostic tests registered in GAL (Gerenciador de Ambiente Laboratorial/Laboratory Environment Manager) in the Ministry of Health of Brazil were analyzed. The reactive samples were selected by their place of occurrence, date and demographic profile. The results showed that the Brazilian states with the highest incidence of reactive samples were respectively Rio de Janeiro 31.04% (149/480) and Minas Gerais 29.37% (141/480). The year with the highest number of reactive samples was 2017, with 47.29%, (227/480). Regarding the demographic indicators, the urban environment outstand itself with the highest number of incidents, 33.33% (160/480). It's noticed a balanced incidence among males 52.91%, (254/480) and females 47.08% (226/480). About race/color, most were white 18.54%, (89/480). The most incident age group was 0 to 10 years 40.00% (192/480). We point out in this study that although bartonellosis is a well-known disease, there is still a shortage of papers describing the distribution of the disease in Brazil, so it is necessary to carry out more investigative studies, in order to better clarify the epidemiological profile of the cases and thus to assist health services in the early diagnosis, treatment and decision-making.