For decades, it has been a big challenge to directly and accurately measure an irregularly shaped area for a tumor volume evaluation of prostate cancer. All current methods are not ideal for different reasons. An objective, practical, accurate, and reliable method for measuring of prostate cancer volume is needed, in particular in modern precision medicine setting, pursuing accuracy and quality of health care.
By using this mathematical method, we were able to easily obtain the accurate tumor volume percentage, which has never been so objective, accurate, and practical before. The method can be easily applied using scanned H&E pathological slides - including surgical slides, fine needle aspirate (FNA) slides, and even digitally scanned pictures, particularly when there are separate areas of interest on one slide.