In this study, we evaluated the stability of three common housekeeping genes, GAPDH, beta-Actin, and 18S-rRNA, in human neuroblastoma SHSY-5Y cells exposed to varying levels of steroid hormones like progesterone (P4) and testosterone. Housekeeping genes serve as reliable internal controls, assumed to maintain consistent expression across diverse tissues and experimental conditions. Since steroid hormones act as ligand-activated transcription factors, directly impacting gene transcription, the id...

In critically ill patients, induced hypothermia or active temperature control to avoid fever are used for neuroprotection. The aim of this study was to determine the feasibility and performance of a novel temperature management system inpatients after cardiac arrest, with neurological fever or due to COVID-19 infection....