Skin Manifestations and SARS-Cov-2 Infection: First the Egg or the Chicken?
Fabiana Tezza, MD, PhD, Giustina De Silvestro, MD, and Gino Gerosa, MD
Article Type: Case Report | First Published: June 27, 2020
In Europe the outbreak due to SARS-CoV-2 took place in Lombardia and Veneto regions which are located in northern Italy. As April 30th, in Italy there were a total of 205,463 SARS-CoV-2 positive cases, with 18,149 in-hospital patients and 27,967 COVID-19 related deaths. Patients with COVID-19 have a wide range of symptoms: Fever, dry cough and dyspnea being the most common; other symptoms can include myalgia or fatigue, runny nose, diarrhea and vomiting. Some patients might experience anosmia an...
Pemphigoid Gestationis: A Third-Trimester Multigravida with a Severe Disease
López Gutiérrez Andrea Fernanda, Gonzalez Saldaña Sandra, Mendez Flores Raul Gerardo, Gomez Cevallos Teresa Aranzazu and Salas Nuñez Lupita Nazaret
Article Type: Case Report | First Published: June 13, 2020
Pemphigoid gestationis is a rare autoimmune vesiculobullous disease that occurs during pregnancy or postpartum. It is caused by circulating IgG autoantibodies that target the extracellular non-collagenous domain of the hemidesmosomal protein BP180. Urticarial papules and plaques with posterior development of tense vesicles and bullae with an erythematous background are the hallmark of the disease. It affects both primigravidas and multigravidas and can occur in any trimester or postpartum but pr...
Manuka Honey and Pediatric Patients: A Review
Paola Martina Marra, DDS, MS, Rossella Santoro, MS, Giuseppe Diana, MS, Angelo Itro, MD, MS and Annalisa Itro, PhD
Article Type: Review Article | First Published: June 11, 2020
Manuka is a monofloral honey with New Zealand and Australian origins. It takes its name from the L. scoparium or tea-tree (manuka or tea tree) plant, whose flowers rich in pollen and nectar feed the bees during the production of honey. To be labeled as "New Zeland manuka honey", bees must use at least 70% of the pollen and nectar from manuka. This honey has nutritional properties similar to those of other types of honey even if, containing some active ingredients, it seems to inherit many phytot...
Hand Rejuvenation with CaHA Guided By Ultrasound
Article Type: Case Report | First Published: May 25, 2020
The effectiveness of the use of calcium hydroxyapatite for hand rejuvenation is well documented in the literature, but studies on anatomy are conflicting. The aim of the present study is to show the application of calcium hydroxyapatite in dorsal hand by distal proximal technique and concomitant visualization by USG 15 Mhz, combined to literatura to define, ensuring the injection safety in the correct plan....
Longstanding Eruptive Keratoacanthoma of the Neck Arising From a Tattoo
Misbah Yehya, DO, Arnaud Batchou, OMS and Thomas Simpson, MD
Article Type: Case Report | First Published: June 10, 2020
Keratoacanthoma (KA) is a cutaneous neoplasm arising from follicular hair cells on sun exposed regions of the skin, particularly the head and neck. Their pathology remains controversial thus distinguishing between KA and squamous cell carcinoma (SCC) has proven to be difficult over the years. Some expert pathologists consider KA a precursor to SCC, while others define it as a well-differentiated variant of SCC or an abortive malignancy with low potential of progression to a full invasive squamou...
Linear Iga Bullous Dermatosis in Crohn's Disease: A Case Report
Ruba Ibrahim, MD, Gil Armoni, MD, Georgina-Maria Sarika, MD and Vered Molho-Pessach, MD
Article Type: Case Report | First Published: May 20, 2020
Linear IgA bullous dermatosis (LABD) is a rare autoimmune, vesiculo-bullous skin disease. It has been previously reported in association with inflammatory bowel disease, particularly ulcerative colitis. We report a case of LABD in a patient suffering from Crohn's disease who received tumor necrosis factor-α inhibitor therapy and developed LABD several months later. Linear IgA bullous dermatosis (LABD) is a rare autoimmune, vesiculobullous skin disease, characterized by linear deposition of IgA ...
Bowen's Disease in the Thenar Eminence: A Case Report
Rafaela Pais Serras, Marta Duarte, Maria Manuel Mendes and Maria Manuel Mouzinho
Article Type: Case Report | First Published: May 01, 2020
Bowen's disease is a squamous cell carcinoma in situ that can degenerate into an invasive squamous cell carcinoma. Early diagnosis and treatment are crucial. There are several therapeutic options available but the most successful is surgical excision with a safety margin. We present a case report of an atypical Bowen's disease in an uncommon location, for which was performed surgical excision with 1 cm of safety margin and then the secondary defect was covered by a skin graft. No complications w...
Albumin, Important Therapy & When to Use It in Ten Patients (Adult & Child): Case Report
Nathasia and Sukmawati Tansil Tan
Article Type: Case Report | First Published: February 03, 2020
Toxic epidermal necrolysis (TEN) is a life-threatening drug reaction that requires immediate medical treatment. Mortality due to TEN cases is quite high until now and the main cause reported is multiple organ dysfunction syndrome. A 7-year-old child, was diagnosed TEN with 86% blistered skin, after receiving Metampiron. Given 20% albumin 50 ml from the first day treated until 20 days, also fluid resucitation, steroids, antibiotics, vitamin C, neurobion, paracetamol, antihistamines, oral hygiene,...
Comparative Study of the Online Over-The-Counter Hair Loss Products
Article Type: Original Article | First Published: January 04, 2020
There are tremendous amount of the overthe- counter (OTC) hair loss products available online and widely purchase all over the world by many consumers. We conducted this study to evaluate some popular and widely used OTC hair loss products that are introduced by famous online retailer websites. Most of hair loss products are natural products, vitamins, minerals, amino acids and proteins. The products found in the top sellers are different between the online retailers regarding their type, side, ...