Open Access DOI:10.23937/2377-3634/1410019

Magnesium and Type 2 Diabetes: An Update

Mario Barbagallo and Ligia J. Dominguez

Article Type: Review Article | First Published: January 26, 2015

The link between magnesium (Mg) deficiency and type 2 diabetes mellitus is well known. Type 2 diabetes is frequently associated with both extracellular and intracellular Mg deficits. A chronic latent Mg deficit or an overt clinical hypomagnesaemia is common in subjects with type 2 diabetes, especially in those with poorly controlled glycemic profiles. Insulin and glucose are important regulators of Mg metabolism. Intracellular Mg plays a key role in regulating insulin action, insulin-mediated-gl...

 Open Access DOI:10.23937/2377-3634/1410018

Relationship between Type of Family and its Relationship to Metabolic Control in Patients with Type 2 Diabetes Mellitus

Ixba-Villegas Mario Alberto, Marquez-Gonzalez Horacio, Jimenez-Baez Maria Valeria and Cantellano-Garcia Diana Michelle

Article Type: Research Article | First Published: January 16, 2015

Objective: To estimate the association between familiar function and metabolic control in patients with T2DM treated in a DiabetIMSS module in a first-level medical unit in Cancun, Quintana Roo, Mexico. Methods: A cross-sectional, prospective and analytical study was conducted. In patients with T2DM and the target population included patients with T2DM who attended the module DiabetIMSS in Cancun, Quintana Roo. Included patients with T2DM between 20 and 80 years of age who received attention in ...

 Open Access DOI:10.23937/2469-570X/1410005

Comparative Characterization of Canine and Human Mesenchymal Stem Cells Derived from Bone Marrow

Bertolo A, Schlaefli P, Malonzo-Marty C, Baur M, Potzel T, Steffen F and Stoyanov J

Article Type: Research Article | First Published: January 19, 2015

Bone marrow is a major source of Mesenchymal Stem Cells (MSC), which are used in tissue engineering and other autologous stem cell therapies. Studies designed to use large canine models and translate the results to human practice must take into account the ex vivo and in vitro differences in the bone marrow samples. A set of morphological and physiological markers was used to compare MSC derived from canine and human bone marrow. Despite anticlotting treatment, frequent bone marrow clotting was ...

 Open Access DOI:10.23937/2469-570X/1410004

Murine CD133+CD49flow/+ Cells Derived from ESCs Differentiate into Insulin Producing Cells in vivo

Jesus Ciriza, Christa Caneda, Bryce McLelland and Jennifer O. Manilay

Article Type: Research Article | First Published: December 31, 2014

Pancreatic progenitors have been identified and isolated during embryonic development showing their potential to differentiate into insulin producing cells after transplantation. Subsequently, they have been proposed as an alternative to the treatment of Type I diabetes. However, fetal pancreata represent a limited donor supply and we proposed that ESC-derived pancreatic progenitors are another possible option....

 Open Access DOI:10.23937/2378-3516/1410012

New Treatment Strategies for Influenza

Luis del Carpio-Orantes

Article Type: Mini Review | First Published: January 28, 2015

After the pandemic influenza H1N1 2009, there are many lessons learned regarding the diagnosis and treatment of patients affected by this virus. However, there have also been a number of contingencies that have greater concern to the world population, mainly by new types as infectious outbreaks, as well as the report of virus mutations that confer resistance to common treatment widely used. For new outbreaks have resulted in a new calamity, after the A (H1N1) pdm09, mainly mentioned the influenz...

 Open Access DOI:10.23937/2378-3516/1410011

An Enlarging Airway Foreign Body

Vijay Hadda, Kavitha Venkatnarayan, Karan Madan, Anant Mohan and GC Khilnani

Article Type: Case Report | First Published: January 26, 2015

A 25-year-old female patient presented with dry coughs of 20 days duration and fever for four days. Examination of respiratory system revealed no significant abnormality. Chest radiograph was normal. CT scan of the thorax revealed endobronchial opacity in the right main bronchus suggestive of a foreign body. Patient retrospectively recollected history of betel nut aspiration just prior to onset of symptoms. Flexible bronchoscopy revealed a large sized blackish-brownish large foreign (betel nut) ...

 Open Access DOI:10.23937/2378-3001/2/1/1019

Recurrent Ischemic Strokes and Headaches Originating from Lambl's Excrescences: A Case-Report

Oana Dumitrascu and Evgeny Tsimerinov

Article Type: Case Report | First Published: January 31, 2015

Determining recurrent stroke etiology and subsequent therapeutic approaches is an important, but not always straightforward task. Lambl's Excrescences (LE) are cardiac valve strands that can be a source of recurrent cerebral ischemic events. We report the case of a 60 year old female that was seen in neurologic consultation for recurrent ischemic strokes. The patient developed migraine headache with complex auras at the age of 59. She reported three admissions for ischemic strokes in the past ye...

 Open Access DOI:10.23937/2378-346X/1410008

Macular Hole Formation Following Choroidal Neovascularization Treatment in A High Myopic Eye with Epiretinal Membrane

Yusaku Yoshida, Manabu Yamamoto, Takeya Kohno and Kunihiko Shiraki

Article Type: Case Report | First Published: January 21, 2015

Purpose: To report on the development of macular hole after treatment of choroidal neovascularization (CNV) in a patient with high myopia and epiretinal membrane (ERM). Methods: Retrospective single case report.Patients: A 60-year-old man presented with reduced vision in his right eye. On the initial examination, the right eye was high myopic with decimal best-corrected visual acuity (BCVA) of 0.3. Results: A subretinal grayish-white lesion was seen at the macula with hemorrhage, and optical coh...

 Open Access DOI:10.23937/2377-9004/1410020

Endoscopic Conservative Treatment for an Ureterovaginal Fistula Caused by Foreign Body

DeLeon E, Lankford D, Allman D, Phillibert D, Paolucci M, Gore S and Clare C

Article Type: Case Report | First Published: January 20, 2015

Foreign body placement in the vagina is a rare cause of ureterovaginal fistula. A fistula is often due to an unrecognized injury to the ureter, most commonly after gynecologic pelvic surgery, such as during hysterectomy for benign indications. This manuscript will discuss a case of a 34-year-old African American female who presents with a history of sexual assault and a one month history of urinary incontinence. Physical examination revealed clear liquid in the vaginal vault and a malodorous for...

 Open Access DOI:10.23937/2378-3672/1410004

Development of a Method for Detection of Shigatoxin-Producing Escherichia coli Belonging to Clinically Important Twelve O Serotypes Based on the Combination of PickPen-Assisted Immunomagnetic Separation and Loop-Mediated Isothermal Amplification

Ahmad Yaman Kayali, Oscar Escalante-Maldonado, Varaporn Vuddhakul, Kazuko Seto, Yoshitsugu Nakaguchi, and Mitsuaki Nishibuchi

Article Type: Original Article | First Published: January 22, 2015

Not only O157 Shigatoxin-producing Escherichia coli (STEC) but some of non-O157 STECs are attracting attentions as clinically important STEC and a possible food-borne spread of these pathogens is becoming a worldwide concern. In this study, we developed a sensitive, specific, and simple method to detect STECs of clinical significance in retail beef so that it can be used even in resource-limited countries. We designed and fie-tuned a protocol characterized by PickPen devise-assisted immunomagnet...