Open Access DOI:10.23937/2378-3656/1410021
Ocular Lyme Disease Simulating Acute Posterior Multifocal Placoid Pigment Epitheliopathy
Mingwu Wang, Rahul N. Khurana, Jill J. Hopkins and Narsing A. Rao
Article Type: Case Report | First Published: March 12, 2015
A 27-year old man presented with ocular symptoms and signs of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) who was also confirmed to have acute Lyme Disease (LD) by serology. The patient was treated timely for systemic LD and the APMPPE-like ocular findings regressed. Possible mechanism linking APMPPE and LD was discussed in conjunction with acute syphilitic posterior placoid choroiditis, another spirochete infection....
Open Access DOI:10.23937/2378-346X/1410017
Congenital Retinal Macrovessel with Normal Visual Acuity: A Case Report
Harsimran K Bhatia, Shekhar Sharma and Laxminarayana P
Article Type: Case Report | First Published: March 12, 2015
Congenital retinal macrovessel is a large aberrant vessel discovered as an incidental finding. These aberrant vessels are mostly single, unilateral veins. CRMs do not affect vision unless there are associated foveolar cysts, foveal ectopic, pigmentary changes at fovea, macular haemorrhage, exudates, serous macular detachment or the macrovessel crosses the fovea. Thorough clinical evaluation and investigations are valuable in diagnosis and follow-up of such cases and aid in timely management of a...
Open Access DOI:10.23937/2378-3648/1410012
Analysis of the Methylation Pattern of SOX2 and OCT4 Genes in Astrocytomas
Wallax Augusto Silva Ferreira, Mariana Diniz Araujo, Nilson Praia Anselmo, Maria Lucia Harada and Barbara do Nascimento Borges
Article Type: Research Article | First Published: February 27, 2015
Astrocytoma is a common aggressive intracranial tumor and a formidable challenge in clinic. Association of the altered DNA methylation pattern of the promoter CpG islands has been found in many human tumors. OCT4 and SOX2 are essential transcription factors for embryonic development and play key roles in determining the fate of stem cells....
Open Access DOI:10.23937/2377-9004/1410026
The Evolution of Laparoscopy in the Management of the Ovarian Mass: Challenges Overcome, Challenges Remaining
Mohamad S Mahmoud
Article Type: Opinion | First Published: March 13, 2015
While laparotomy and ultrasound guided aspiration were still the common approaches for the management of ovarian cysts in the late 20th century, the introduction of laparoscopy in the surgical armatarium has begun changing this approach as early as the late 1960's. In his publication dated 1969, Dr Stepto from the royal college of obstetrics and gynecology describes his own techniques using laparoscopy to diagnose the type of the ovarian cyst by aspirating its content or by biopsy of the cysts i...
Open Access DOI:10.23937/2378-3516/1410015
Primary Mediastinal Goiter Resected via Cervical Approach
Benito Vargas-Abrego, Pablo Alvarez-Maldonado, Rosa M Alcazar-Lopez, Francisco C Lorente-Ludlow and Carlos Nunez-Perez Redondo
Article Type: Case Report | First Published: February 24, 2015
Primary mediastinal goiter is a rare entity. In most cases their finding is incidental. Excision is mandatory because of the risk of compression of vital structures within the chest. We report the case of a primary posterior mediastinal goiter that was resected through a cervical approach....
Open Access DOI:10.23937/2378-346X/1410016
Nasal Mucosa Graft and Lamellar Keratoplasty as Treatment in Recurrent Pterygium
Ricardo Romero, Ricardo Romero-Fontenlos, Almudena del Hierro, Alvaro Arbizu, Margarita Sanchez-Orgaz and Ana Romero
Article Type: Case Report | First Published: March 02, 2015
Aim: We propose the use of lamellar keratoplasty associated with nasal mucosal graft for the reconstruction of the ocular surface in multiple recurrent pterygium. Methods: Our patient had undergone four operations of nasal pterygium excision on the right eye, using different surgical procedures: simple excision, excision plus conjunctival autograft, removal plus amniotic membrane graft, excision plus mucosa oral graft plus mitomycin C....
Open Access DOI:10.23937/2377-4630/2/1/1022
Management of Anesthesia in A Patient with Myasthenia Gravis
Semih Baskan, Dilsen Ornek, Adem Guney, Fahri Acar, Ozlem Sacan and Mustafa Baydar
Article Type: Case Report | First Published: March 09, 2015
Purpose: This report describes the management of anesthesia in a patient with myasthenia gravis, undergoing thymectomy. Clinical features: The patient was a 22-yr-old female. Thoracic computed tomography revealed a thymoma and a right-side paratracheal lymph node 46x44mm in size. A thymectomy operation was required....