Open Access DOI:10.23937/2378-3656/1410022
Effect of Cardiac Resynchronization Therapy on Left Ventricular Diastolic Function
Kammoun Ikram, Marrakchi Sonia, Jebri Faten and Kachboura Salem
Article Type: Research Article | First Published: March 23, 2015
Cardiac Resynchronization Therapy (CRT) improves systolic performance in Heart Failure (HF). However, the effects of CRT on Left Ventricular (LV) diastolic function were variable and not fully understood. The aim of this study was to determine the effects of cardiac resynchronization therapy on LV diastolic filing pattern and the relation between the diastolic filing pattern and the response to CRT....
Open Access DOI:10.23937/2469-5718/1510001
Electromyographic Cross-Spectral Analysis of Antagonist Muscle Coactivation
Travis W. Beck
Article Type: Research Article | First Published: March 20, 2015
The purpose of this study was two-fold: (1) to compare the responses for traditional EMG amplitude measures with those from the crossspectrum approach for assessing agonist-antagonist interaction, and (2) to examine changes in the agonist-antagonist interaction for the elbow flexors and extensors with increases in movement velocity. Eighteen healthy, college-aged subjects (mean ± SD age = 21.8 ± 2.7 yrs) volunteered to perform maximal, concentric isokinetic contractions of the dominant elbow fle...
Open Access DOI:10.23937/2469-5742/1510003
A Comparison of Prostatic Acinar Adenocarcinoma Gleason 3+4 versus 4+3 in Different Laboratory Practice Settings
Celia Maria Jesuino Bittencourt, Daniel Abensur Athanazio, Andreia Carvalho dos Santos, Erica Curvelo Dantas Senna, Tania Maria Correia Silva and Luiz Antonio Rodrigues de Freitas
Article Type: Research Article | First Published: March 20, 2015
Objective: To evaluate Gleason 7 tumors from radical prostatectomy specimens that were stratified by 3+4 and 4+3 status, focusing on the clinical and morphologic features. Methods and results: In the first series of 20 Gleason 7 tumors processed by total embedding, cases with 4+3 status were associated with a higher proliferation index. In a second series of 106 Gleason 7 tumors processed by partial embedding, 4+3 status was associated with higher preoperative serum prostate-specific antigen lev...
Open Access DOI:10.23937/2469-5734/1510004
Recurrent Osseous Choristoma Involving the Mandibular Buccal Vestibule: A Case Report
Curtis Gregoire, Clayton Davis, Martin Bullock and Thomas Steeves
Article Type: Case Report | First Published: March 19, 2015
This case report is the third ever reported of a recurrent intraoral osseous choristoma. The lesion had manifested twice in the left mandibular buccal vestibule of a 63-year-old Caucasian female. The patient was treated with wide local excision on both occasions. We believe that the lesions may have arisen as a result of previous trauma, although the exact etiology of the lesions is unknown. Interestingly, the recurrent lesion contained satellite nodules of bone, which suggests that the osseous ...
Open Access DOI:10.23937/2378-3397/1410019
The New Paradigm for the Treatment of Chronic Pancreatitis
Rainer W.G. Gruessner
Article Type: Opinion | First Published: March 10, 2015
Effective treatment of chronic pancreatitis remains one of the greatest surgical challenges to date. Th incidence of chronic pancreatitis ranges from 3 to 10 cases per 100,000 populations per year worldwide. In the United States alone, more than 50,000 hospitalizations per year are caused by this disease. Chronic pancreatitis is an inflammatory process, progressive and irreversible in nature that eventually leads to complete destruction of pancreatic parenchyma and ductal structures....
Open Access DOI:10.23937/2378-2951/1410023
Erythropoietin Treatment Improves Peak VO2 and Oxygen Uptake Efficiency Slope without Changing VE vs. VCO2 Slope in Anemic Patients
Ayumi Goda, Haruki Itoh, Yoshiko Ebi, Kumiko Kondo, Tomoko Maeda and Toshitsune Shimada
Article Type: Research Article | First Published: March 20, 2015
The aim of this study was to evaluate the improvement in hemodynamic, metabolic, and ventilatory response during exercise along with the improvement of anemia with EPO treatment in anemic hemodialysis patients. Methods: Thirty-seven hemodialysis patients with anemia (48.8 +/- 13.6 years) received EPO (1500 or 3000 unit, 3 times a week). Parameters measured prospectively before and after EPO treatment included hemoglobin, cardiac output by dye dilution method, echocardiography, and cardiopulmonar...
Open Access DOI:10.23937/2377-4630/2/1/1024
The Concentration for Loss of Consciousness by Propofol does not differ between Morning and Afternoon
Kumiko Tanabe, Shigemi Matsumoto, Mayumi Nakanishi and Hiroki Iida
Article Type: Short Communication | First Published: March 20, 2015
Background: Circadian rhythms influence the pharmacology and effects of anesthetic agents such as local anesthetics, general anesthetics, and muscle relaxants. However, the influences of the circadian rhythm on new anesthetics such as propofol are unknown. Results: Thirty-seven patients underwent induced anesthesia at 8:30. Twenty-eight patients were induced between 14:00 and 16:00.There was no significant difference between the two groups in the predicted blood concentration, the predicted effe...