Open Access DOI:10.23937/2469-5831/1510002
Drug Treatment Comparison for Total Knee Replacement Surgery
Kevin Soderholm and Rhonda Magel
Article Type: Research Article | First Published: September 02, 2015
Data from over 2000 patients receiving knee replacement surgery was gathered from a hospital system in the Midwestern United States. The age group that each patient belonged to was noted, under age 65 or 65 years of age and older, as well as their gender. A variety of drugs in each of three drug categories was studied as to their association with total hospital cost, length of stay, prevalence of early readmissions and prevalence of blood transfusions. The drug categories included spinal blocks,...
Open Access DOI:10.23937/2378-346X/1410037
Coexisting Normal- Tension Glaucoma and Deficiencies of Folic Acid and Vitamin B6 (Pyridoxal)
Tetsuya Sugiyama
Article Type: Case Report | First Published: September 06, 2015
A 43-year-old man presented with bilateral visual field defect. Large disc cupping, retinal nerve fiber layer defect, and normal intraocular pressure were found in both eyes. Although the patient was prescribed an anti-glaucoma eye drop, the visual field defect deteriorated after two months of treatment. The patient was diagnosed with sensory, taste, and hearing impairments, as well as depression, caused by folic acid and vitamin B6 (pyridoxal) deficiencies at an internal medicine department. Th...
Open Access DOI:10.23937/2469-5769/1510005
Topic: Acute Kidney Injury in Children: 3-Year Data Review from Ghana
Sampson Antwi, Anima Sarfo, Abigail Amoah, Anna Serwaa Appia and Esther Obeng
Article Type: Research Article | First Published: September 14, 2015
Acute kidney injury (AKI) is a relatively common condition encountered in everyday paediatric practice. It remains a significant contributor to preventable deaths especially in resource constraint regions of the world largely due to lack of dialysis services.
This 3-year data analysis (2010-2012) was undertaken to determine the aetiology and treatment/mortality outcomes of children with AKI presenting to a Teaching Hospital in Ghana. AKI was defined in this analysis by the RIFLE and KDIGO cri...
Open Access DOI:10.23937/2469-584X/1510004
Hormonal Therapy for GI Angiodysplasia: Out of Hope After Failure of the Scope?
Ujjwal Kumar, Kevin Cowley and Frederick Weber
Article Type: Case Report | First Published: September 14, 2015
Angiodysplasia of the gastrointestinal (GI) tract can present both diagnostic and therapeutic challenges. Despite the recent advances in endoscopy, many patients continue to suffer from recurrent bleeding. We report a remarkable case of a multi-year history of transfusion-requiring obscure overt recurrent GI bleeding, refractory to multiple endoscopic therapies as well as both octreotide and thalidomide. Upon initiation of hormonal therapy, the patient's bleeding completely resolved, with comple...
Open Access DOI:10.23937/2469-584X/1510003
Effect of Biologics on the Outcomes of Inflammatory Bowel Disease: A Retrospective Study on a Large Pediatric Cohort
Hoda M. Malatyr, Bincy Abraham, Mina S. Emil, George D. Ferry and Elizabeth A. Garnett
Article Type: Research Article | First Published: September 11, 2015
The incidence of inflammatory bowel disease (IBD) in children has increased over the past 20 years and treatment with biologics is increasingly used.
Objective: We assessed the associations of biologics to IBD outcomes in children.
Methods: A retrospective investigation was conducted on a cohort of children with IBD between 1988/2008 who were enrolled in the Pediatric IBD registry. The diagnosis of IBD was based on clinical, radiological, endoscopic, and/or histological examinations. Clini...
Open Access DOI:10.23937/2378-3656/1410053
New Onset Nephropathy in a Patient with Psoriatic Skin and Joint Disease
Savvas Psarelis, Sophia Corsava, Kyriakos Polycarpou, Kyriakos Ioannou, Ioanna Zouvani and Elena Nikiphorou
Article Type: Case Report | First Published: September 05, 2015
We present the case of a 38-year-old male patientwho presented with new onset nephropathy on a background of psoriatic skin and joint disease. The pathogenesis and link between nephropathy with psoriatic disease is discussed, along with potential diagnostic and management challenges. This case highlights that nephropathy in psoriatic skin and joint disease can and does occur and high vigilance is necessary especially in patients taking potentially nephrotoxic drugs. The complexity of these cases...
Open Access DOI:10.23937/2378-3656/1410052
A Case of Psoriasis in an HIV Positive Male
Omar F Merchant and Wayne X Shandera
Article Type: Case Report | First Published: August 29, 2015
Patients with Human Immunodeficiency Virus (HIV) infection have an increased risk for several variants of psoriasis as well as being refractory to standard treatment regimens. While psoriasis does not affect HIV survival, quality of life may be significantly impaired and these considerations warrant special attention with management. We report a case of psoriasis in a 43-year-old Hispanic male with HIV infection, adequately managed with antiretroviral therapy. He presented with chronic and persi...
Open Access DOI:10.23937/2378-3656/1410051
Mycotic Aneurysm of Native Renal Artery: Case Report and Review of the Literature
Arru Luca, De Magistris Luigi, Arendt Charlie, Pillet Jeanchristophe, Azagra Juan Santiago, Goergen Martine and Pouthier Dominique
Article Type: Case Report | First Published: August 28, 2015
Introduction: Renal native artery is an uncommon localisation of mycotic aneurysm that involves most frequently the artery of renal transplant in immuno-suppressed patients. Septic embolization often occurs during endocarditis and direct infection could complicate endovascular procedures with device placing.
Case report: We herein describe the case of a leaking mycotic aneurysm of the native renal artery (MANRA) in a renal transplanted patient, successfully treated by open aneurysmectomy and ...
Open Access DOI:10.23937/2378-3656/1410050
General and Oral Aspects in Apert Syndrome: Report of a Case
Villarreal-Becerra Einer, Luis Sanchez-Soler, Angel Espias-Gomez, Leonard RH Jr, Julio Herrero-Payo and Eduardo Chimenos-Kustner
Article Type: Case Report | First Published: August 26, 2015
Background:The present paper describes the general and oral manifestations in a 32-year-old man previously diagnosed with Apert syndrome. Clinical examination revealed features of acrocephalosyndactyly. The patient was found to have a flattened occiput with frontal prominence, abnormal contour of head (brachycephaly), shallow and downward slanting orbits with bilateral proptosis, hypertelorism, retruded midface, and prognathic mandible.Dental anormalies were present in a patient....