Open Access DOI:10.23937/2469-5734/1510021

Third Molar Transplantation: A Case Report

BENTO Gabriela, HADDAD Marcela Filie and Mariano Ronaldo Celio

Article Type: Case Report | First Published: November 25, 2015

Nowadays, implant-supported prostheses has been evidenced and shown to have excellent results. One of the reasons for dental treatments is to maintain natural healthy functional teeth throughout the lifespan. However, when this is not possible, dental autotransplantation can be an option. This method has some advantages when compared with other ways of oral rehabilitation such as avoiding jaw development changes, representing a conservative treatment. It could be called "biological prosthesis".....

 Open Access DOI:10.23937/2572-3243.1510007

Immune-mediated Mechanisms and Immunotherapy of Duchenne Muscular Dystrophy

Ruojie He and Cheng Zhang

Article Type: Review Article | First Published: March 01, 2016

The immune response is a critical mechanism for dystrophic muscle pathology and muscle wasting in Duchenne Muscular Dystrophy (DMD). The inflammatory processes are supposed to associate with activation of the innate immune response like macrophages infiltration, T cell-mediated immune response, generation of cytokines and chemokines and the aberrant activation of NF-kB signaling pathway, which contribute to severe muscle necrosis and fibrosis....

 Open Access DOI:10.23937/2572-3243.1510006

Use of CD-ROMS for Digital Image Viewing During New Pediatric Orthopaedic Consults - Do We Need a Standardized Viewer for Digital Imaging?

Czoch Wojciech, William Hennrikus, Alexander Kish and Douglas Armstrong

Article Type: Research Article | First Published: February 01, 2016

The purpose of this study is to perform a practice management evaluation of CD-ROM imaging. Thirty-three patients who presented with images on a CD-ROM before and 33 patients after the addition of DICOM software were compared. Data collected included; site of origin of the CD-ROM, time in minutes spent to access the images, number of computers tried until images were viewed, cases of failure to view the images, quality of the images on a Likert 1-5 scale, and the need to repeat images....

 Open Access DOI:10.23937/2469-5777/1510030

A Peculiar Case

Raoul van Vugt and Peters J

Article Type: Clinical Image | First Published: February 06, 2016

A 65-year-old male with a history of an oligodendroglioma (for which debulking surgery in 2012) was presented in our emergency department by ambulance paramedics after he had fallen in his kitchen. Initial examinations revealed an awake, hemodynamically normal patient with a knife penetrating the medial side of his face, just below the right eyeball. Looking at the depth and position of the knife, the assessment was that it was a sharp, pointed knife that went in with a lot of force....

 Open Access DOI:10.23937/2469-5777/1510029

18-Fluordesoxiglucose Positron Emission Tomography (PET) in Evaluating Neurological Prognosis after Cardiac Arrest Resulting from Hanging: A Case Report

Marco Ciapetti, Andrea Cecchi, Marco Mangini, Valentina Berti, Matteo Bartolini, Alberto Pupi and Adriano Peris

Article Type: Case Report | First Published: January 30, 2016

We report clinical and 18 - FDG PET features of a 58 years old woman found in cardiac arrest after an attempt of hanging. The patient was resuscitated and transferred to our Emergency Intensive Care Unit (ICU), where she was treated for 23 days and then she was discharged to a neuro rehabilitation long term care center with a Glasgow Coma Scale (GCS) of 6. A 18 F - FDG PET with semi quantitative glucose metabolism measurements was performed showing a global reduction in supra tentorial areas, in...

 Open Access DOI:10.23937/2469-5777/1510028

Radial Head Fractures Treated with Open Reduction and Internal Fixation

Moghaddam A, Raven TF, Kaghazian P, Studier-Fischer S, Swing T, Grutzner PA and Biglari B

Article Type: Research Article | First Published: January 21, 2016

Radial head fractures are responsible for 2 to 5% of adult fractures. Especially problematic is the treatment of dislocated and unstable fractures which often have a worst prognosis. The purpose of this study was to evaluate the results of open reduction and internal fixation (ORIF) in the treatment of radial head fractures....

 Open Access DOI:10.23937/2469-5777/1510027

Missed Spinal Lesions in Traumatized Patients

Ana M Cervan de la Haba, Miguel Rodriguez Solera J, Miguel S Hirschfeld Leon and Enrique Guerado Parra

Article Type: Case series | First Published: January 15, 2016

Overlooked spinal injuries and delayed diagnosis are still common in traumatized patients. The management of trauma patients is one of the most important challenges for the specialist in trauma. Proper training and early suspicion of this lesion are of overwhelming importance. The damage control orthopaedics, diagnosis and treatment algorithm applied to multitrauma patients reduces both morbidity and mortality in polytrauma patients due to missed lesions....

 Open Access DOI:10.23937/2378-3001/3/2/1042

MR-Guided Laser Interstitial Thermal Therapy for the Treatment of Medically Refractory Epilepsy

Shasha Wu, James X. Tao, Naoum P. Issa, Sandra Rose and Peter Warnke

Article Type: Review Article | First Published: March 02, 2016

Resective epilepsy surgery is highly effective in the treatment of medically refractory epilepsy. However, it involves an open craniotomy and carries the risks of permanent functional deficits and cosmetic concerns. Multiple minimally invasive surgical approaches have been attempted to destroy seizure foci with minimal damage to surrounding normal tissue. Here we review the currently available minimally invasive surgical approaches for epilepsy, with an emphasis on MR-guided laser interstitial t...

 Open Access DOI:10.23937/2378-3001/3/1/1041

A Critical View of Neurofeedback Experimental Designs: Sham and Control as Necessary Conditions

Marta Alino, Marien Gadea and Raul Espert

Article Type: Short Note | First Published: February 27, 2016

Neurofeedback (NF) emerged to employ neural feedback via EEG as an evolution of biofeedback in the 1960. Specifically, NF entails to learn to self-control the brain activity according to operant principles through a visual, auditory or even tactile representation of participant's brain activity as a feedback, with the aim of improving mental states, whether or not in clinical conditions....

 Open Access DOI:10.23937/2378-3001/3/1/1040

Introducing a Developed Model of Reversible Cardiac Arrest to Produce Global Brain Ischemia and Its Impact on Microtubule-Associated Protein Tau Phosphorylation at Ser396

Shohreh Majd, John H. Power, Simon A. Koblar and Hugh J. M. Grantham

Article Type: Original Article | First Published: February 26, 2016

Brain ischemia is a consequence of stroke and cardiac arrest (CA), leading to short and long-term neurological impact involving cognitive function as well as dementia. An accurate, simple and reproducible model of CA ischemia and reperfusion is valuable in assessing the response to ischemia and therapeutic interventions. In the current study the effectiveness of a reversible model of CA has been assessed through examining the brain response in expressing tau and hyperphosphorylated tau (p-tau) p...