Open Access DOI:10.23937/2377-9004/1410088
Sacral Nerve Stimulation and Fecal Incontinence: Current Uses and Emerging Trends
Jennifer E Hrabe, Brooke Gurland and Tracy L Hull
Article Type: Short Review | First Published: May 21, 2016
Fecal incontinence (FI) is a socially devastating condition affecting both men and women. Patients often suffer in silence, as FI is frequently unreported. It is commonly seen in patients who also experience urinary incontinence (UI). Risk factors for FI include obstetrical trauma as well as increasing age. Until recently, treatment options were limited and consisted of medical therapy or surgical options with limited efficacy or high morbidity. Initially used for UI, sacral nerve stimulation ha...
Open Access DOI:10.23937/2377-9004/1410087
Isolated Rectal Laceration Following Normal Spontaneous Vaginal Delivery and Delayed Rectal Hemorrhage
Yuzuru Anzai
Article Type: Case Report | First Published: May 21, 2016
A 37-year-old Para 0 patient underwent an induction of labor due to chronic hypertension. She had a successful normal vaginal delivery but experienced acute cardiovascular collapse immediately following the delivery requiring massive transfusion. She also was found to have an isolated rectal laceration without laceration of anus or anal sphincter. After she was discharged home she presented to the emergency room with rectal hemorrhage 5 days after the initial repair requiring an additional two u...
Open Access DOI:10.23937/2377-9004/1410086
Dextroposition of the Heart Reflected Mosaic Fetal Trisomy 18
Mohamed A Satti, Frederico G Rocha, Erin Beaver and Jeffrey M Dicke
Article Type: Case Report | First Published: May 02, 2016
Anatomy scan of a 22 year old prima gravida at 19w4d showed a viable IUP with unilateral choroid plexus cyst and dextroposition of the heart without any other observed structural malformation. Amniocentesis revealed a normal male pattern for chromosomes 13, 18, 21, X and Y by fluorescence in situ hybridization (FISH). However, chromosomal microarray analysis (CMA) for circulating fetal DNA in maternal blood was consistent with mosaic Trisomy 18. The karyotype of cultured dividing cells confirmed...
Open Access DOI:10.23937/2469-567X/1510021
Comprehensive Programme to Prevent Cervical Cancer - the Case of Hungary
Dobrossy L, Oroszi B, Kovacs A and Budai A
Article Type: Case Report | First Published: April 30, 2016
The overall purpose of a comprehensive cervical cancer prevention programme is to coordinate HPV vaccination (primary prevention) and cervical screening (secondary prevention). Harmonization of the HPV vaccination and population screening is expected to reduce the burden of cervical cancer by reducing human papillomavirus (HPV) infections, and detecting cervical pre-cancer lesions and invasive cancer earlier, providing timely treatment. In 2015, 80% of 7th class schoolgirls between 12-13 years o...
Open Access DOI:10.23937/2469-570X/1410034
Bone Marrow Cells Repair and Regenerate Acute and Chronic Injured Liver without Primary Evidence of Neoplastic Changes
Prakash Baligar, Veena Kochat, Snehasish Mukherjee, Abinaya Sundari T, Vikash Kumar, Zaffar Equbal and Asok Mukhopadhyay
Article Type: Research Article | First Published: May 28, 2016
All major metabolic and synthesis functions of liver are significantly perturbed in case of critical injury. Though liver regenerates by itself following acute injury, this process is impaired in case of chronic injury. In both cases, unless liver is allowed to regenerate by proving appropriate support, either internally or externally, depending up on the extent of injury it ceases to function and transplantation remains the only available treatment option. ...
Open Access DOI:10.23937/2469-570X/1410032
Development of Better Treatments for Retinal Disease Using Stem Cell Therapies
Rachel Gater, Dan Nguyen, Alicia J El Haj and Ying Yang
Article Type: Short Review | First Published: May 28, 2016
The retina is a complex, light sensitive tissue layer on the inner surface of the eye, which functions to translate light stimuli into nerve impulses which travel to the brain via the optic nerve. Retinal diseases such as glaucoma, macular degeneration and retinitis pigmentosa can lead to significant vision problems and even blindness. Although there are some existing treatments for retinal disease, current treatments are invasive, need to be regularly repeated and do not have the capability of ...
Open Access DOI:10.23937/2469-5807/1510039
Japanese Crisis of HPV Vaccination
Masayuki Sekine, Risa Kudo, Sosuke Adachi, Manako Yamaguchi, Yutaka Ueda, Tomomi Takata, Akiko Morimoto, Yusuke Tanaka, Asami Yagi, Etsuko Miyagi and Takayuki Enomoto
Article Type: Review Article | First Published: May 30, 2016
Cervical cancer has been increasing in younger generation, especially in 20's and 30's, so it has been a serious problem that the disease leads to loss of fertility as an urgent issue in Japan. HPV vaccine was added to the national list of routine vaccinations for Japanese girls aged 12 to 16 years by law since April, 2013. Three months later, however, the Japanese Ministry of Health, Labour, and Welfare suspended recommendations for HPV vaccination after several reports of possible adverse even...
Open Access DOI:10.23937/2572-4215.1510008
An Innovative Technique for Refractory Plantar Fasciitis in Ipsilateral Complex Regional Pain Syndrome
Mihir M Patel, Sahvan M Patel, Sia S Patel and David I Steinberg
Article Type: Case Report | First Published: June 03, 2016
This is a case report of utilizing a technique to help a patient resolve refractory plantar fasciitis in the ipsilateral limb that she had a blunt force work place injury that led to complex regional pain syndrome Type I. Complex regional pain syndrome can be very difficult to treat. When a patient develops orthopedic pathology in the same area as the complex regional pain syndrome, the patient can have devastating outcomes. Additionally, many solutions to the orthopedic pathology can lead to in...