Open Access DOI:10.23937/2377-3634/1410062

The Impact of Energy Drink Consumption on Vascular Endothelial Function

R Matthew Brothers

Article Type: Research Article | First Published: June 07, 2016

Vascular endothelial dysfunction contributes to a variety of cardiovascular and metabolic diseases. Despite anecdotal reports of adverse cardiovascular and hemodynamic effects of energy drink consumption there has been very little scientific research conducted on this important topic. Furthermore, the limited research available has not yielded consistent results. This study tested the hypothesis that consumption of a commercially available energy drink would have no effect on endothelial functio...

 Open Access DOI:10.23937/2377-3634/1410061

Ethanolic Extract of Bauhinia forficata: Metabolic Effects in Diabetic and Normoglycemic Rats

Liana de Oliveira Gomes, Francislaine Aparecida dos Reis Livero, Aline Maria Stolf, Carlos Eduardo Alves de Souza, Michele Pontes Werneck, Cristiane Vizioli de Castro Ghizoni, Maria Helena Verdan, Jose Ederaldo Queiroz Telles, Rosangela Locatelli Dittrich, Maria Elida Alves Stefanello, Jurandir Fernando Comar and Alexandra Acco

Article Type: Original Article | First Published: June 06, 2016

Diabetes is a group of metabolic diseases characterized by hyperglycemia and associated complications, such as dysfunction and failure of the eyes, kidneys, nerves, brain, heart, and blood vessels. Diabetes may result from defects in secretion and/or insulin action involving specific pathogenic processes, including destruction of pancreatic beta cells, insulin resistance, and insulin secretion disorders. The estimated prevalence of diabetes nowadays is about 150 million people worldwide, and thi...

 Open Access DOI:10.23937/2572-4193.1510021

Piriform Margin Augmentation as a Treatment for Persistent Nasal Valve Dysfunction: A Cadaveric Investigation and Report of Initial Clinical Results

Randolph B Capone, Michael M Kim and Dane J Genther

Article Type: Clinical Study | First Published: June 02, 2016

Background: Revision nasal valve reconstruction is one of the few treatment options available for patients with persistent nasal valve dysfunction after primary functional rhinoplasty. Revision nasal surgery is challenging, hampered by the presence of scar tissue, incorporated grafts, and the morbidity of obtaining additional autologous cartilage. Objective: In order to enhance nasal valve function while avoiding revision nasal surgery, a sublabial technique was developed to increase the project...

 Open Access DOI:10.23937/2469-5777/1510037

Bilateral Osteochondrosis of Medial Cuneiform and Tarsal Scaphoid: A Case Report

Ceccarelli F, Carolla A and Calderazzi F

Article Type: Case Report | First Published: May 27, 2016

Osteochondrosis has been found in most of the bones of the body. We report a rare case report of bilateral osteochondrosis of medial cuneiform and tarsal scaphoid. A five year-old white child with a completely benign medical history presented with bilateral foot pain. Radiographical studies showed a bilateral irregular outline and an increased density of medial cuneiforms and tarsal scaphoids. Physical activity restriction and medical therapy appear to be sufficient for pain relief. This "syndro...

 Open Access DOI:10.23937/2378-3001/3/4/1052

Endoscopic Biopsy using High-Dose Fluorescein Sodium for Malignant Brain Tumors

Takeshi Okuda, Mitsugu Fujita, Hiromasa Yoshioka, Takayuki Tasaki, Shuichi Izumoto and Amami Kato

Article Type: Case Report | First Published: July 01, 2016

The utility of endoscopic biopsy using high-dose fluorescein sodium in biopsy of malignant brain tumors was investigated. The subjects were 9 patients with malignant brain tumors (malignant lymphoma 5, glioblastoma 3, metastatic brain tumor 1). After making an incision in the dura mater, 20 mg/kg fluorescein sodium were administered intravenously. A transparent sheath was then inserted under neuronavigation guidance. To observe the tumor, an endoscopic biopsy was performed using normal white lig...

 Open Access DOI:10.23937/2378-3001/3/3/1051

Neurology and Cardiac Arrhythmias

Zhengqin Zhai, Min Tang and Shu Zhang

Article Type: Short Review | First Published: June 25, 2016

A host of studies on the cardiac innervation have found a complex link known as cardiac autonomic nervous system (CANS), connecting extracardiac nerves, intracardiac ganglia, and myocardial cells. Now it is well known that CANS plays a critical role in regulating the functions of the heart and its imbalance is regarded as one of the major causes of cardiac arrhythmias. With the development of medical technology and the advancement of ideas, several novel therapies of arrhythmias through modulati...

 Open Access DOI:10.23937/2378-3001/3/3/1050

Permanent Memory Deficits with Normal MRI Following Heat Stroke after Physical Activity and Sauna

Massimiliano Ruggeri and Priscilla Rosini

Article Type: Case Report | First Published: June 24, 2016

Heat stroke is the result of high heat stress and determines multi-organ dysfunction with predominant encephalopathy. Heat stroke only rarely leads to permanent neurologic deficits with a propensity to cerebellar dysfunction while memory disorders are very unusual. We report a unique case of a patient who suffered from a heat stroke after strenuous physical activity and sauna, resulting in persistent memory deficit with normal acute and follow-up normal MRI. Neuropsychological assessment suggest...

 Open Access DOI:10.23937/2377-9004/1410091

Clinical Observation of 84 Days Delayed Delivery of the Second Fetus in Twin Pregnancy

Julia E Dobrokhotova, Oleg V Makarov, Pavel V Kozlov and Pavel A Kuznetsov

Article Type: Case Report | First Published: July 04, 2016

Perinatal morbidity and mortality in preterm labor is significantly higher than in on-term delivery. The share of preterm infants accounts for approximately 70% of all cases of early neonatal mortality. One of the most important independent risk factors for preterm birth is multiple pregnancy. The risk of delivery before 30, 32 and 34 weeks in twin pregnancy is about 4%, 8% and 16%, respectively. In general, the frequency of preterm labor with twins is 6 times higher than in singleton pregnancie...

 Open Access DOI:10.23937/2377-9004/1410090

The Use of Advanced Reproductive Technologies while Breastfeeding: A Role for in Vitro Maturation

Catherine S Rose and Bruce I Rose

Article Type: Case Report | First Published: July 01, 2016

Breastfeeding provides significant health benefits for both the mother and child. There is a decreased risk of ovarian and breast cancer, the development of diabetes, and myocardial infarction for women who breastfed their child. The risk decreases even more significantly if the mother is exclusively breastfeeding without supplementation of formula and the longer the mom and baby choose to breastfeed. For the child, breastfeeding decreases the risk of childhood leukemia, childhood obesity, asthm...

 Open Access DOI:10.23937/2377-9004/1410089

Aggressive Complete Hydatidiform Mole Coexistent With A Normal Fetus During Pregnancy: Is There A Correlation Between Outcome, and Serum HCG Levels? A Report on 2 Cases and Review of the Literature

Nathalie Renard, SWA Nij Bijvank, HH De Haan, J van Eyck, JWB de Groot, RHM Verheijen and AJ Kruse

Article Type: Case Series | First Published: June 01, 2016

wo cases of complete hydatidiform mole with coexisting fetus are described. In the first case, the mole of this twin pregnancy displayed an aggressive behavior with early maternal onset of severe pre-eclampsia and lung and liver metastases. The second patient opted for termination of pregnancy prior to a possible onset of complications. Existing literature on this topic is also reviewed, in particular on the role of serum hCG levels to predict a favourable fetal prognosis....