Open Access DOI:10.23937/2378-3419/1410081

Bioactive Peptides from Legumes as Anticancer Therapeutic Agents

Gonzalez-Montoya Marcela, Cano-Sampedro Eden and Mora-Escobedo Rosalva

Article Type: Review Article | First Published: July 19, 2017

Food proteins are a source of nutraceutical and bioactive peptides that promote health and prevent diseases. Legume seed proteins have been widely studied to produce peptides (protein fragments) with a diversity of biological activities....

 Open Access DOI:10.23937/2469-5718/1510066

Medical Management of Males and Females in Return to Learn and Return to Play after Concussion: An Observational Study

Amy Hassen, Ariel Klingaman and Jennifer Reneker

Article Type: Research Article | First Published: July 21, 2017

This study aimed to 1) Describe differences in medical management between males and females after a concussion, and 2) Explore factors associated with the number of days to Return to Learn (RTL) and Return to Play (RTP). 111 subjects, aged 12-19 with sports-related concussion participated....

 Open Access DOI:10.23937/2469-5726/1510053

Algorithm for Treatment of Hip and Knee Osteonecrosis: Review and a Presentation of Three Example Cases

Kim-Orden Michael, Barrett Kody and Khatod Monti

Article Type: Case Series | First Published: July 19, 2017

Osteonecrosis (ON) of the hip and knee can be a source of severe morbidity for affected individuals. Although several risk factors and explanations for the pathogenesis of ON have been recognized, there exists little consensus in the literature as to the appropriate clinical management....

 Open Access DOI:10.23937/2469-5726/1510052

Rheumatoid Arthritis of the Craniovertebral Junction: Surgical Strategies, Current Approach and Proposal of a New Therapeutic Algorithm

Luis Eduardo Carelli Teixeira da Silva, Alderico Girao Campos de Barros and Marcelo Glauber da Silva Pereira

Article Type: Review Article | First Published: June 12, 2017

Rheumatoid Arthritis (RA) is a systemic inflammatory disease with an autoimmune feature and an etiology that is still unknown. It is characterized by a symmetrical peripheral polyarthritis that affects primarily the small joints of hands and feet, with several levels of extra-articular manifestation....

 Open Access DOI:10.23937/2572-3987.1510011

Prolonged Coagulopathy Following Rattlesnake Envenomation Responsive to Antivenom: A Case Report

Megan Z Roberts, Brian P McKinzie, Stuart M Leon, Stephen A Fann and Nicole M Bohm

Article Type: Case Report | First Published: July 19, 2017

Venom-specific immunoglobulin G fragments are used for the management of patients with North American crotalid envenomation. In this case, ongoing coagulopathy and clinically significant sequelae required a protracted course of antivenom therapy in a patient experiencing severe rattlesnake envenomation....

 Open Access DOI:10.23937/2378-3516/1410073

Pulmonary Complications of Sickle Cell Disease in the Pregnant Patient

Kevin G Lazo, Joanna B Eldredge, Anne Press and Bushra A Mina

Article Type: Review Article | First Published: July 14, 2017

Respiratory complaints are common symptoms in pregnancy, and it is important to delineate whether the causative factor is cardiac, pulmonary, or physiologic in origin. The pathophysiology of Sickle Cell Disease (SCD) can further complicate the differential diagnosis....

 Open Access DOI:10.23937/2378-3516/1410072

Impact of Adopting 2014 Guidance for Palivizumab Prophylaxis for Children Previously Considered at High Risk for Severe Respiratory Syncytial Virus Disease

Rachel D Quick, Kathryn Merkel, Don K Murphey, Marisol Fernandez and Sarmistha B Hauger

Article Type: Original Article | First Published: June 22, 2017

This is a report of pediatric patients hospitalized with Respiratory Syncytial Virus Infection (RSV) during the season prior to, and 2 seasons following the 2014 palivizumab prophylaxis guidance release. The primary aim was to determine the effect of the 2014 guidance on children no longer considered eligible for prophylaxis....

 Open Access DOI:10.23937/2378-3516/1410071

Crimean-Congo Hemorrhagic Fever: What Do We Know about Pulmonary Injury? A Compilation of Evidence

Francisco X Leon-Roman Ismael Carrillo-Martin, Gema Fernandez-Plana and Salvador Diaz-Lobato

Article Type: Case Report | First Published: June 12, 2017

Crimean-Congo Haemorrhagic Fever (CCHF) is a lethal vector-borne viral infection produced by a Nairo virus, a genus of the Bunyan viridae family. Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is a single-stranded RNA virus with three segments (large, medium, and small), two envelope proteins (Gn and Gc) and an RNA-dependent RNA polymerase....

 Open Access DOI:10.23937/2469-5718/1510065

The Long-Term Effects of Stand-up Paddle Boarding: A Case Study

Ben Schram, Wayne Hing and Mike Climstein

Article Type: Case Study | First Published: July 12, 2017

The association between inactivity and poor quality of life has been well documented. A major barrier to exercise is a perceived lack of time and lack of enjoyment of exercise modalities. Stand up Paddle Boarding (SUP) is an aquatic physical activity deemed easy to learn....

 Open Access DOI:10.23937/2469-5718/1510064

Land Based Resistance Training and Youth Swimming Performance

Marie Clare Grant and Mykolas Kavaliauskas

Article Type: Research Article | First Published: July 08, 2017

Resistance training has been shown to have both performance-enhancing and injury-reducing benefits in youth athletes. The benefits are somewhat overlooked by many swimming coaches, therefore the effects of a structured resistance training programme in highly trained youth swimmers was investigated....