Open Access DOI:10.23937/2469-5769/1510030

The Different Approaches of Single Lung Ventilation in Infants with Pulmonary Malformation

Costanza Tognon, Luisa Meneghini, Francesco Fascetti Leon and Piergiorgio Gamba

Article Type: Original Article | First Published: February 17, 2018

Since many years, feasibility and safety of thoracoscopic surgery in infants with pulmonary malformations has been confirmed. Nevertheless, infants present some problems caused by the anatomical and physiological peculiarities typical of the age and of the size of the structures. Several ways to overcome these difficulties have been proposed to assure efficacy and safety of mono-pulmonary ventilation. The knowledge of the infant's respiratory physiology is essential to prevent complications and ...

 Open Access DOI:10.23937/2378-3397/1410062

Maxium Sutureless Closed Haemorrhoidectomy for Symptomatic Haemorrhoids Grades III and IV: An Observational Cross-sectional Study

Jawad Kadhim S Al-Dhahiry

Article Type: Research Article | First Published: February 07, 2018

A symptomatic haemorrhoidal disease is one of the most common anorectal diseases. Haemorrhoids grades I and II can be medically treated but haemorrhoids grades III and IV are surgically treated. Although Conventional Haemorrhoidectomy Techniques (CH) are commonly used but they are associated with some major complications. Many novel techniques have been introduced to overcome these complications such as Maxium Haemorrhoidectomy (MH)....

 Open Access DOI:10.23937/ijnd-2017/1710002

Apolipoprotein E Fragmentation within Lewy Bodies of the Human Parkinson's Disease Brain

Troy T Rohn and Jacob M Mack

Article Type: Research Article | First Published: February 23, 2018

Although harboring the Apolipoprotein E4 (APOE4) allele is a well-known risk factor in Alzheimer's disease (AD), whether a similar risk holds true for Parkinson's disease (PD) is currently not known. To investigate whether apoE pathology is present in PD, an immunohistochemical study was undertaken with fixed, human PD brain sections from the substantia nigra utilizing a recently characterized antibody that detects an amino-terminal fragment of apoE. This antibody, termed the apoE cleavage fragm...

 Open Access DOI:10.23937/2469-5823/1510089

Eating Difficulties in Newly-Onset Stroke Patients: A Qualitative Inquiry of Nurses' Perceptions of the Situation

Wai Sze Mavis LAI, Lisa Pau Le LOW and Ka Yin Kayla WONG

Article Type: Research Article | First Published: February 12, 2018

Eating difficulties are one of the challenges experienced by stroke survivors. It is necessary to examine eating difficulties from a broader perspective and not only focus on swallowing. As nurses play a vital role in ensuring good nutrition, greater attention should be given to explore this phenomenon. This paper reports a study to explore nurses' perceptions of caring for newly-onset acute stroke patients with eating difficulties. Twelve registered nurses from two medical wards of an acute hos...

 Open Access DOI:10.23937/iamm-2017/1710001

Potential of Supercritical Solvent Impregnation for Development of Materials with Antibacterial Properties

Irena Zizovic

Article Type: Review Article | First Published: November 20, 2017

Supercritical solvent impregnation is a modern technique which exploits the unique transport properties and qualities of supercritical fluids such as low viscosity, high diffusion coefficients, densities as in a liquid state and zero surface tension, for the fabrication of novel materials. The mentioned properties allow deep penetration of supercritical fluid with a dissolved bioactive substance into a solid matrix enabling even distribution of the active substance through the whole volume of th...

 Open Access DOI:10.23937/ijcb-2017/1710001

New Therapeutic Perspectives for the Cognitive Deficit in Alzheimer's Disease: Pharmacological Modulation of Ca2+/cAMP Signaling Interaction

Afonso Caricati Neto and Leandro Bueno Bergantin

Article Type: Review Article | First Published: November 18, 2017

Due to the involvement of the imbalance of Ca2+ homeostasis in neuronal cells in the pathogenesis of several neurodegenerative disorders such as Alzheimer's Disease (AD), the use of drugs to prevent or attenuate this imbalance emerged as a new therapeutic perspective for this disease. Then, our recent discovery of the involvement of the interaction between intracellular signaling pathways mediated by Ca2+ and cAMP (Ca2+/cAMP signaling interaction) in the neurotransmission and neuroprotection, an...

 Open Access DOI:10.23937/2474-3682/1510082

Infiltrating Squamous Cell Carcinoma of the Penis

Mohamed El Amraoui, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Image Article | First Published: February 21, 2018

Infiltrating squamous cell carcinoma (SCC) of the penis is a rare tumor of easy diagnosis. The poor prognosis of this cancer justifies a rigorous oncological management which is often mutilating and badly accepted in our context. We present a case in an elderly man....

 Open Access DOI:10.23937/2474-3682/1510081

When a Psoriasis Shows Its Claws!!!

Mohamed El Amraoui, Naoufal Hjira and Mohammed Boui

Article Type: Image Article | First Published: February 21, 2018

Secondary amyloidosis (AA) is a real complication of chronic inflammatory diseases, including chronic inflammatory rheumatism. It is associated with a reserved prognosis justifying the use of all available therapies for the control of inflammation, the sole guarantor of a more favorable evolution. However, it rarely complicates the inflammatory dermatosis including psoriasis and remains far from the minds of young practitioners, hence the interest of recalling, through this clinical case, to wat...

 Open Access DOI:10.23937/2474-3682/1510080

Pseudoxanthoma Elasticum: Beyond the Skin

Mohamed El Amraoui, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Image Article | First Published: February 21, 2018

The pseudoxanthoma elasticum (PXE) is a metabolic genetic disorder affecting connective tissue characterized by calcification and fragmentation of elastic fibers, which essentially affects the skin, the eyes and the cardiovascular system. We presented a typical example of a pseudoelastic xanthoma in a patient followed in ophthalmology and cardiology and it was the dermatological lesions that had helped to correct the diagnosis....

 Open Access DOI:10.23937/2469-5777/1510058

Improved Outcomes after Surgical Stabilization of Rib Fractures in Patients with Polytrauma and Associated Chest Wall Fractures

Maria Alfaro, Ruby Skinner and Andrea Pakula

Article Type: Original Article | First Published: February 17, 2018

Non-operative management of rib fractures can lead to significant morbidity such as chronic pain, and dyspnea. Up to 40% may also fail to return to work. Over the last decade rib fixation has made resurgence and there are emerging data supporting early fixation in patients that fail aggressive pain control even in non-flail segments. We describe our early experience with early rib fixation in a small cohort of patients with severe chest wall injury....