Open Access DOI:10.23937/2378-3656/1410203
Urothelial Carcinoma with Intracranial Lesion: Metastasis or Abscess?
Tania Jain, Siddharth Gupta, Natasha Robinette, Dongping Shi and Ulka N Vaishampayan
Article Type: Case Report | First Published: February 21, 2018
Isolated central nervous system and dural metastasis from urothelial cancer are exceedingly rare. We describe 2 unique cases of intracranial lesions in patients with urothelial carcinoma-one with isolated brain and dural brain metastasis, and another with Nocardia brain abscess....
Open Access DOI:10.23937/2378-2951/1410110
Mass Regression after Aortic Valve Replacement in Aortic Stenosis: A Comparison between
Giordano Tasca, FrancescoTrinca, Beatrice Riva, Douglas Skouse, Elisabetta Lobiati, Caterina Chiara DeCarlini and Amando Gamba
Article Type: Research Article | First Published: April 11, 2018
Left ventricular (LV) hypertrophy is a form of adaptation to a chronic cardiac overload. In the setting of aortic stenosis (AS), LV hypertrophy develops to limit the increase of LV systolic wall stress. Aortic valve replacement (AVR), is expected to eliminate the LV burden, inducing regression of LV hypertrophy....
Open Access DOI:10.23937/cabjd-2017/1710003
Use of the LRINEC Score in Diabetic Patients
Timothy T Cheng, Joseph Carreau and Alexandra Schwartz
Article Type: Original Research Article | First Published: April 11, 2018
The LRINEC (laboratory risk indicators for necrotizing fasciitis) score was developed in 2004 to help distinguish necrotizing fasciitis from severe soft tissue infections. Some of the laboratory tests, however, may be elevated at baseline in diabetic patients....
Open Access DOI:10.23937/2572-4061.1510010
Recent Advances in Mercury Detection; Towards Enabling a Sensitive and Rapid Point-of-Check Measurement
Nurfatini Busairi and Amir Syahir
Article Type: Research Article | First Published: April 09, 2018
Heavy metals emission, in particular, mercury is ever increasing due to global urbanization and industrialization. Due to increasing number of health problems related to heavy metals contamination, monitoring it becomes a crucial task for authorities and environmentalists. Therefore, the development of a nanobiosensing technique that can detect mercury ions as low as 1 ppb for its limit of quantification is necessary to provide sufficient information to ensure a sustainable and healthy environme...
Open Access DOI:10.23937/2377-4630/1410062
Perioperative Cardiac Stent Thrombosis Versus Bleeding: A Clinical Dilemma in Trauma Patients
Nwokolo Omonele O and Wegner Robert C
Article Type: Case Report | First Published: April 05, 2018
Heart disease is prevalent in current patient population at an increasing level. Some of these patients have had interventions such as stent placements to improve quality of life and are started on antiplatelet therapy for a definite period of time or indefinitely based on their risk factors, comorbidities or type of stents placed. When these patients present to the hospital with major trauma, the surgical and anesthetic management threads a delicate line between protection of the stents and pre...
Open Access DOI:10.23937/ijor-2017/1710004
Clinical Results of Radiotherapy for Locally Advanced Stage III Pancreatic Cancer: A Single Institutional Experience
Yoshiomi Hatayama, Masahiko Aoki, Hideo Kawaguchi, Katsumi Hirose, Mariko Sato, Ichitaro Fujioka, Mitsuki Tanaka, Koji Ichise, Shuichi Ono and Yoshihiro Takai
Article Type: Original Article | First Published: March 31, 2018
Fifteen patients with locally advanced stage III pancreatic cancer underwent radiotherapy with or without concurrent chemotherapy between July 2006 and April 2014. We used 10 MV X-rays and multiple coplanar (two to four) fields. The number of fractions ranged between 20 and 28 with a fraction size of 1.8Gy. A total dose of 36-50.4Gy at the isocenter of the planning target volume (PTV) was administered to each patient. Fourteen patients received chemotherapy during radiotherapy. The cumulative su...
Open Access DOI:10.23937/2378-346X/1410084
The Effect of Prostaglandin Analogues on Central Corneal Thickness
Umut Duygu Uzunel
Article Type: Research Article | First Published: March 31, 2018
Prostaglandin (PG) analogues are being widely used to reduce Intraocular Pressure (IOP) in glaucoma patients. These drugs reduce IOP by stimulation of aqueous humor drainage primarily through the uveoscleral outflow pathway but significant effects on trabecular outflow facility also have been reported. The suggested mechanism of IOP reduction involves aqueous humor outflow enhancement through the uveoscleral pathway accompanied by collagen degradation in the ciliary body. This collagen degradati...
Open Access DOI:10.23937/iacph-2017/1710001
Human Physiology in Extreme Heat and Cold
Braian M Beker, Camila Cervellera, Antonella De Vito and Carlos G Musso
Article Type: Review Article | First Published: March 31, 2018
The interest in the human body physiological capacity to adapt to extreme heat and cold conditions has increased enormously in the last few decades because of global warming and the consequent changing temperatures. The human body has multiple thermoregulatory mechanisms to counter the external extreme temperatures whose main objective is to keep temperature homeostasis within normal values. As exposure time to these stressful conditions increases and the external temperature becomes even more e...